A Network Pharmacology Study and Experimental Validation to Identify the Potential Mechanism of Heparan Sulfate on Alzheimer’s Disease-Related Neuroinflammation by Dong-Uk Kim, Bitna Kweon, Jinyoung Oh, Yebin Lim, Gyeongran Noh, Jihyun Yu, Hyang-Rin Kang, Tackmin Kwon, Kwang youll Lee, Gi-Sang Bae

“…Results: We performed functional enrichment analysis of common genes between HS target genes and AD-NI gene sets and obtained items such as the “Cytokine-Mediated Signaling Pathway”, “Positive Regulation Of MAPK Cascade”, and “MAPK signaling pathway”. To confirm the predicted results, the anti-inflammatory effect of HS was investigated using lipopolysaccharide (LPS)-stimulated BV2 microglia cells. …”
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Relative Navigation in LEO by Carrier-Phase Differential GPS with Intersatellite Ranging Augmentation by Alfredo Renga, Michele Grassi, Urbano Tancredi

“…In this paper, an augmented CDGPS navigation filter is proposed for the formation of two satellites characterized by a short, varying baseline, relevant to next generation Synthetic Aperture Radar missions. Specifically, a cascade-combination of dynamic and kinematic filters which processes double-differenced code and carrier measurements on two frequencies, as well as local inter-satellite ranging measurements, is used to get centimeter-level baseline estimates. …”
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Angiotensin Converting Enzyme 2, Angiotensin-(1-7), and Receptor Mas Axis in the Kidney by Sergio Veloso Brant Pinheiro, Ana Cristina Simões e Silva

“…In this regard, Angiotensin- (Ang-) (1-7) was recognized as a biologically active product of the RAS cascade with a specific receptor, the G-protein-coupled receptor Mas, and that is mainly formed by the action of the angiotensin-converting enzyme (ACE) homolog enzyme, ACE2, which converts Ang II into Ang-(1-7). …”
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An Over-Actuated Hexacopter Tilt-Rotor UAV Prototype for Agriculture of Precision: Modeling and Control by Gabriel Oliveira Pimentel, Murillo Ferreira dos Santos, José Lima, Paolo Mercorelli, Fernanda Mara Fernandes

“…The employed control architecture consists of cascaded proportional (P)-proportional, integral and derivative (PID) controllers using the successive loop closure (SLC) method on the five controlled degrees of freedom (DoFs). …”
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Integrated estimation of parameters of radio transmitter power amplifier with automatic mode adjustment by two-frequency test signal by P. V. Sak

“…Method is proposed for calculation of energy gain and efficiency factor (efficiency) when applying automatic control of supply voltage of output cascades of shortwave transmitters intended for modulation with speech signals. …”
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24-Epibrassinolide, a Phytosterol from the Brassinosteroid Family, Protects Dopaminergic Cells against MPP+-Induced Oxidative Stress and Apoptosis by Julie Carange, Fanny Longpré, Benoit Daoust, Maria-Grazia Martinoli

“…Brassinosteroids (BRs) are phytosterols recognized to promote stress tolerance of vegetables via modulation of the antioxidative enzyme cascade. However, their antioxidative effects on mammalian neuronal cells have never been examined so far. …”
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Biocatalytic enantioselective formation and ring-opening of oxetanes by Xia Hua, Yuan-Fei Wang, Xiao Jin, Hong-Yin Yu, Hui-Hui Wang, Yong-Zheng Chen, Nan-Wei Wan

“…Additionally, both the enantioselective oxetane formation and ring-opening processes are proven scalable for large-scale transformations at high substrate concentrations, and can be integrated efficiently in a one-pot, one-catalyst cascade system. This work expands the enzymatic toolbox for non-natural reactions and will promote further exploration of the catalytic repertoire of halohydrin dehalogenases in synthetic and pharmaceutical chemistry.…”
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Modulated Model Predictive Speed Controller for PMSM Drives Employing Voltage-Based Cost Function by Ahmed Aboelhassan, Shuo Wang, Giampaolo Buticchi, Vasyl Varvolik, Michael Galea, Serhiy Bozhko

“…Various electrical drive systems have widely implemented the classical cascaded field-oriented control (FOC) topology, including speed loop, current loop, and modulation. …”
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The interplay of carbon and nitrogen distribution: Prospects for improved crop yields by Oluwaseun Olayemi Aluko, Zhixin Liu, Xuwu Sun

“…This review summarises our current understanding of C and N transport mechanisms, explores and compares different physiological and molecular approaches involved in the C–N distribution cascade, including cotton and other plant species. …”
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A joint learning method for low-light facial expression recognition by Yuanlun Xie, Jie Ou, Bihan Wen, Zitong Yu, Wenhong Tian

“…Then, we design a joint loss to train the LLENet with FER network in a cascade manner, so that the FER network can guide the LLENet to gradually perceive and restore discriminative features which are useful for FER during the training process. …”
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Progress in mid-infrared optoelectronics for high-speed free-space data throughput by Frédéric Grillot, Thomas Poletti, Salvatore Pes

“…In addition, mid-infrared wavelengths benefit from reduced atmospheric scattering and signal distortion, making them much more reliable for free-space optical communications. Quantum cascade devices such as lasers, modulators, and detectors operating in the MWIR and LWIR ranges are seen as high-potential candidates for data transmission under poor weather conditions or in degraded environments. …”
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Advancements in Antioxidant-Based Therapeutics for Spinal Cord Injury: A Critical Review of Strategies and Combination Approaches by Yang-Jin Shen, Yin-Cheng Huang, Yi-Chuan Cheng

“…Spinal cord injury (SCI) initiates a cascade of secondary damage driven by oxidative stress, characterized by the excessive production of reactive oxygen species and other reactive molecules, which exacerbate cellular and tissue damage through the activation of deleterious signaling pathways. …”
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Rosiglitazone Induces Mitochondrial Biogenesis in Differentiated Murine 3T3-L1 and C3H/10T1/2 Adipocytes by James X. Rong, Jean-Louis D. Klein, Yang Qiu, Mi Xie, Jennifer H. Johnson, K. Michelle Waters, Vivian Zhang, Jennifer A. Kashatus, Katja S. Remlinger, Nan Bing, Renae M. Crosby, Tymissha K. Jackson, Sam M. Witherspoon, John T. Moore, Terence E. Ryan, Sue D. Neill, Jay C. Strum

“…The timing of the increases was consistent with the cascade of organelle biogenesis, that is, initiated by induction of transcription factor(s), followed by increases in the biosynthesis machinery, and then by increases in functional components. …”
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Anti-Inflammatory Effects of Epoxyeicosatrienoic Acids by Scott J. Thomson, Ara Askari, David Bishop-Bailey

“…The mechanisms by which EETs mediate their effects are largely unknown but may include direct binding to peroxisome proliferator-activated receptors (PPARs), G-protein coupled receptors (GPCRs), or transient receptor potential (TRP) channels, which initiate anti-inflammatory signalling cascades.…”
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Siah2 antagonism of Pard3/JamC modulates Ntn1-Dcc signaling to regulate cerebellar granule neuron germinal zone exit by Christophe Laumonnerie, Maleelo Shamambo, Daniel R. Stabley, Tommy L. Lewis, Niraj Trivedi, Danielle Howell, David J. Solecki

“…Abstract Exiting a germinal zone (GZ) initiates a cascade of events that promote neuronal maturation and circuit assembly. …”
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Iron triggers TvPI4P5K proteostasis and Arf-mediated cell membrane trafficking to regulate PIP2 signaling crucial for multiple pathogenic activities of the parasitic protozoan Tric... by Kuan-Yi Wu, Yen-Ju Chen, Shu-Fan Lin, Hong-Ming Hsu

“…These findings highlight that TvArf220-mediated PIP2-calcium signaling cascade regulates actin cytoskeleton and cytopathogenicity of T. vaginalis. …”
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Determination of a normal orogenic palaeo-geothermal gradient with clay mineral and organic matter indices: a review by Rafael Ferreiro Mählmann, Meinert Rahn, Sébastien Potel, Lan Nguyen-Thanh, Rainer Petschick

“…In the eastern Helvetic Alps and Northern Calcareous Alps similar correlations were found with slightly different slopes. …”
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Turbine Airfoil Leading Edge Film Cooling Bibliography: 1972–1998 by D. M. Kercher

“…Substantial progress has been made in understanding the complex nature of leading edge film cooling from airfoil cascades, simulated airfoil leading edges and environment. …”
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LANCL1 as the Key Immune Marker in Neuropathic Pain by Yu Shi, XueFei Zhang, Qian Fang, Hongrui Zhan, Xianglong Wang, Xiyan Huang, Tao Fan, Wei Liu, Wen Wu

“…In this study, we found that LANCL1 may be a protective factor for NeuP, and the miR-6325/LANCL1 axis may be involved in the occurrence and development of NeuP. Cascade reactions including mast cells, macrophages, and T cells may be an important reason for the aggravation of nerve damage.…”
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Control of Cross Talk between Angiogenesis and Inflammation by Mesenchymal Stem Cells for the Treatment of Ocular Surface Diseases by Fei Li, Shao-zhen Zhao

“…However, it facilitates inflammatory cell filtration and inflammation cascade that disrupt the immune and angiogenesis privilege of the avascular cornea, resulting in ocular surface diseases and even vision loss. …”
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