A prospective study to evaluate the clinical specificity of the cobas® MPX test kit for screening for HIV RNA, HCV RNA, and HBV DNA in blood donation samples using the cobas® 6800... by Lei Zhou, Lin Wang, Xiaofang Gong, Xiaochun Liu, Yaxuan Zou, Yingying Wang, Jinfeng Zeng, Liang Zang

“…Results: Cobas® MPX demonstrated 100.00 % overall percent agreement (95 % CI, 99.22 %-100.00 %) for IDT and 99.89 % (95 % CI, 99.82 %-99.95 %) for PP6. Kappa coefficients were 1.0 for IDT and 0.76 for PP6. …”
Get full text

Isolation and function of a human endothelial cell C1q receptor by M. R. Daha, L. Dunn, R. van den Berg, Y. Muizert-de Lange, A. Gerritsen, L. A. van Es

“…During isolation, C1qR was detected by its capacity to inhibit the lysis of EAC1q in C1q-deficient serum. …”
Get full text

The paediatric liver transplant experience in Johannesburg, South Africa: A broad overview and update by K Kinandu, A Beeton, M Beretta, S Berkenfeld, L Brannigan, R Britz, D Demopoulos, L Doedens, M Duncan, P Gaylard, C Hajinicolaou, W Lowman, H Maher, T De Maayer, V Mudau, S Rambarran, M Reynders, F van der Schyff, B Ströbele, S Tager, E Wessels, J Fabian, J Loveland

“…Since then, significant progress has been made in capacity-building the unit, improving outcomes and enhancing service delivery. …”
Get full text

Comparison of Two Automated Urine Analyzers (URiSCAN Super + YD Diagnostics and Sysmex UC-3500–UF-5000 Urine Chemistry Analyzer) with Routine Microscopy by Durre Aden, Poonam Khambra, Sunil Ranga, Yasir Alvi

“…The results of urine examination consisting of cells, formed elements, and microorganisms were compared between both the automated urine analyzers and microscopy, and the degree of concordance was calculated utilizing Cohen’s kappa (κ) analysis to see the concordance between all three values. …”
Get full text

Stochastic population models to identify optimal and cost‐effective harvest strategies for feral pig eradication by Peter W. Hamnett, Frédérik Saltré, Brad Page, Myall Tarran, Matt Korcz, Kate Fielder, Lindell Andrews, Corey J. A. Bradshaw

“…We developed a stochastic Leslie matrix with compensatory density feedback on survival to project population trajectories from an initial population (N0) of 250 female pigs with an estimated island‐wide carrying capacity (K) of 2500 over 3 and 10 years for populations subjected to an annual harvest of 35%–95%. …”
Get full text

Effects of cold-pressed wheat germ oil and Bacillus subtilis on growth performance, digestibility, immune status, intestinal microbial enumeration, and gene expression of broilers... by Abdel-Moneim Eid Abdel-Moneim, Safaa A.M. Ali, M.G. Sallam, Ahmed M. Elbaz, Noura M. Mesalam, Zangabel S. Mohamed, AbdelRahman Y Abdelhady, Bing Yang, Mohamed Farouk Elsadek

“…This study provides evidence that supplementing heat-stressed broiler diets with a mixture of WGO and B. subtilis enhances antioxidant capacity, immune response, growth performance, and gut integrity via modulating the microbial community and regulating gene expression.…”
Get full text

Classificação da nasalidade de fala de indivíduos com fissura labiopalatina com escalas ordinais distintas by Gisele Fonseca do Carmo, Jeniffer de Cássia Rillo Dutka, Flora Taube Manicardi, Beatriz Campanine Geremias, Maria Inês Pegoraro-Krook, Viviane Cristina de Castro Marino

“…O índice de coeficiente Kappa mostrou concordância intra-avaliador mais favorável para a escala reduzida. …”
Get full text

Mesenchymal stromal cells promote the formation of lung cancer organoids via Kindlin-2 by Zhilin Sui, Xianxian Wu, Jiaxin Wang, ShihJye Tan, Chao Zhao, Zhentao Yu, Chuanyue Wu, Xiaoxiao Wang, Ling Guo

“…However, certain lung cancer cells derived from patients exhibit limited capacity to generate organoids due to inter-tumor or intra-tumor variability. …”
Get full text

Effect of ticagrelor combined with metoprolol extended-release tablets on cardiac function and clinical prognosis in elderly patients with acute coronary syndrome after percutaneou... by Lili Wang, Linlin Gao, Qin Chen, Li Chen, Hui Xu, Ling Sun, Youbin Hu

“…Both groups experienced enhanced exercise capacity, as evidenced by longer exercise duration (ED) and improved 6-min walking test (6MWT) results, with the OG showing superior gains (P < 0.05). …”
Get full text

Effects of dietary Spirulina platensis supplementation on growth performance, whole body composition, antioxidant activity, histological alterations, and resistance to Vibrio parah... by Ragaa A. Ahmed, Samyah D. Jastaniah, Bothaina A. Alaidaroos, Manal E. Shafi, Ehab El-Haroun, Yasmin M. Abd El-Aziz, Ola Hasan Abd El Megeed, Mada M. AL-Qurashi, Safia M.A. Bahshwan, Mohammad Bodrul Munir, Zulhisyam Abdul Kari, Roshmon Thomas Mathew, Moaheda E.H. Eissa, El-Sayed Hemdan Eissa, Amal Elfeky

“…Overall, the present study highlights the potential impact of S. platensis in shrimp diet by showing significant improvements in growth, antioxidant capacity, histological changes and resistance to against V. parahaemolyticus Thus, S. platensis can be recommended as a beneficial feed supplement for the shrimp industry.…”
Get full text

A comparative study evaluating three line immunoassays available for serodiagnosis of equine Lyme borreliosis: Detection of Borrelia burgdorferi sensu lato-specific antibodies in s... by Cornelia V Broeckl, Stephanie Hiereth, Reinhard K Straubinger

“…They are presented as inter-rater agreement and statistic reliability, represented by the Fleiss' kappa coefficient. Agreement scores ranged from poor to moderate depending on group and time-point of blood sample collection. …”
Get full text

Evaluation of Clavulanic Acid Adsorption in MgAl-Layered Double Hydroxides: Kinetic, Equilibrium and Thermodynamic Studies by Marcus Bruno Soares Forte, Élen Cristina Luna Elias, Heloise O. Pastore, Francisco Maugeri Filho, Maria Isabel Rodrigues

“…The experimental isotherm data were well fitted by a linear equilibrium model with the corresponding adsorption constants being K = 0.404, 0.602, 0.849 and 1.083 ℓ/g at 16.5, 19.0, 21.5 and 24.0 °C, respectively, showing an increased adsorption capacity at higher temperatures. Thermodynamic evaluation of the process allowed the Gibbs' free energy (ΔG 0 ), the standard enthalpy change (ΔH 0 ) and the standard entropy change (ΔS 0 ) to be estimated as follows: ΔG 0 = 2.100, 1.301, 0.503 and −0.295 kJ/mol at 16.5, 19.0, 21.5 and 24.0 °C, respectively; ΔH 0 = 94.602 kJ/mol; and ΔS 0 = 0.319 kJ/(mol K), respectively. …”
Get full text

SVM directed machine learning classifier for human action recognition network by Dharmanna Lamani, Pramod Kumar, A Bhagyalakshmi, J. Maria Shanthi, Lakshmana Phaneendra Maguluri, Mohammad Arif, C Dhanamjayulu, Sathish Kumar. K, Baseem Khan

“…The use of traditional machine learning classifiers is done in order to further improve the discriminative capacity of the features that have been learned. To be more specific, we use the latent representations that are stored in HARNet’s fully connected layer and use them as our deep learnt features. …”
Get full text

Addressing evidence needs during health crises in the province of Quebec (Canada): a proposed action plan for rapid evidence synthesis by Quan Nha Hong, Esther McSween-Cadieux, Maxime Guillette, Luiza Maria Manceau, Jingjing Li, Vera Granikov, Marie-Pascale Pomey, Marie-Pierre Gagnon, Saliha Ziam, Christian Dagenais, Pierre Dagenais, Alain Lesage, Thomas G. Poder, Martin Drapeau, Valéry Ridde, Julie Lane

“…Now that the pandemic is over, it is time to put in place actions to improve the capacity of systems to meet knowledge needs in a situation of crisis. …”
Get full text

Ecological impacts of single-axis photovoltaic solar energy with periodic mowing on microclimate and vegetation by Yudi Li, Yudi Li, Alona Armstrong, Alona Armstrong, Christopher Simmons, Noah Z. Krasner, Noah Z. Krasner, Rebecca R. Hernandez, Rebecca R. Hernandez, Rebecca R. Hernandez, Rebecca R. Hernandez

“…With the global market for tracking systems projected to increase annually by 32% in capacity by 2050, understanding their ecological impacts, including those from their operation and management (O&M), is critical but understudied. …”
Get full text

Collecting perspectives on project prioritisation process in the EU co-funded multinational partnership for the assessment of risks from chemicals (PARC) through focus group discus... by Katya Manuella Permana, Maria Tannous, Hanna Mouaziz, Pascal Sanders, Nathalie Bonvallot, Christophe Rousselle

“…Abstract Introduction The European Partnership for the Assessment of Risks from Chemicals (PARC) is a 7-year multinational partnership aimed at consolidating and strengthening European Union’s (EU) research and innovation capacity for chemical risk assessment (RA) to protect human health and the environment. …”
Get full text

Non-lytic spread of poliovirus requires the nonstructural protein 3CD by David Aponte-Diaz, Jayden M. Harris, Tongjia Ella Kang, Victoria Korboukh, Mohamad S. Sotoudegan, Jennifer L. Gray, Neela H. Yennawar, Ibrahim M. Moustafa, Andrew Macadam, Craig E. Cameron

“…ABSTRACT Non-enveloped viruses like poliovirus (PV) have evolved the capacity to spread by non-lytic mechanisms. For PV, this mechanism exploits the host secretory autophagy pathway. …”
Get full text

NLRP3 inflammasome-modulated angiogenic function of EPC via PI3K/ Akt/mTOR pathway in diabetic myocardial infarction by Jia-Peng Li, Shu Qiu, Guang-Jie Tai, Yi-Ming Liu, Wei Wei, Meng-Meng Fu, Pan-Qi Fang, Joseph Nicolao Otieno, Tungalag Battulga, Xiao-Xue Li, Ming Xu

“…However, in the HFD/STZ-induced diabetic mice model combined with myocardial infarction, Nlrp3 knockout EPC significantly restored angiogenic capacity. Mechanically, CEBPB regulated the transcriptional level of Nlrp3 as a transcription factor in EPC. …”
Get full text

The concept of bio-economic mulching in droughty tropical agroecosystems and its trans-season effects on soil hydro-thermal regime and okra performance by Benedict Odinaka Okorie, Justina O. Obi, Geraldine U. Chioke, Sunday E. Obalum, Chinaza J. Onah, Adaobi L. Nnadi, Charles A. Igwe, Martin E. Obi

“…Soil thermal conductivity (0.78to 4.88 W m–1 K–1), thermal diffusivity (3.95 × 10–7 to 35.97 × 10–7 m2 s–1), and heat flux (15.00 to 85.56 W m–2) generally decreased as q increased with BEM application rate particularly during the PRS; the reverse prevailed for volumetric heat capacity (1.33 × 106 to 2.25 × 106 J m–3 K–1). Okra plant height differed (BEM-6 > BEM-4 > BEM-2/BEM-0) in the PRS, but BEM-6 and BEM-4 gave the tallest and shortest plants, respectively in the CRS. …”
Get full text

Semi-standardized evaluation of extraprostatic extension and seminal vesicle invasion with [18F]PSMA-1007 PET/CT: a comparison to MRI using histopathology as reference by Erland Hvittfeldt, Fredrik Hedeer, Erik Thimansson, Kevin Sandeman, David Minarik, Jacob Ingvar, Anders Bjartell, Elin Trägårdh

“…The intraclass correlation coefficient for the PET LCC measurement was 0.68, the kappa values for the visual Likert scales for PET were 0.53 for EPE and 0.63 for SVI. …”
Get full text