Chitooligosaccharides suppress airway inflammation, fibrosis, and mucus hypersecretion in a house dust mite-induced allergy model by Yun-Ho Kim, Chan-Ho Park, Ju Myung Kim, Yeo Cho Yoon

“…In the HDM-induced allergic respiratory model, COS suppressed the infiltration of inflammatory cells around the airways and inhibited the mRNA expression of Th1 immune cytokines in lung tissues, while also reducing the expression of nuclear factor kappa B (NF-κB)-related proteins. Furthermore, the results confirmed the suppression of the levels of immunoglobulin E (IgE) in the blood secreted by mast cells activated by HDM, which led to a reduction in allergic mucus hypersecretion and airway sclerosis.ConclusionIn summary, COS are thought to improve airway resistance by alleviating inflammatory allergic respiratory diseases caused by HDM and are regarded as substances that regulate the balance of the Th1 and Th2 immune systems in epithelial cells affected by mucus hypersecretion.…”
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Diseño de una propuesta educativa en educación física para fomentar andar al colegio en adolescentes by Romina Gisele Saucedo-Araujo, Francisco Javier Huertas-Delgado, Javier Molina-García, Amador Jesús Lara-Sánchez, Palma Chillón, Josef Mitas, Manuel Herrador-Colmenero

“…Conclusiones: Estudiantes y profesores percibieron la propuesta educativa y la aplicación Mystic School como innovadoras y capaces de mejorar las lecciones de educación física. …”
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Effects of Long-Term Dietary Administration of Kale ( Brassica oleracea L. var. acephala DC) Leaves on the Antioxidant Status and Blood Biochemical Markers in Rats by Katarzyna Papierska, Ewa Ignatowicz, Jadwiga Jodynis-Liebert, Małgorzata Kujawska, Róża Biegańska-Marecik

“…Antioxidant potential in serum was measured and expressed as Trolox equivalents antioxidant capacity (TEAC). The kale leaf phytochemicals, i.e., glucosinolates, phenolic acids and flavonols, were quantified. …”
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Newly identified c-di-GMP pathway putative EAL domain gene STM0343 regulates stress resistance and virulence in Salmonella enterica serovar Typhimurium by Kaifeng Chen, Lili Li, Nanwei Wang, Zhouping Zhou, Peng Pan, Chenggang Xu, Dage Sun, Jiayi Li, Changzhi Dai, Dai Kuang, Ming Liao, Jianmin Zhang

“…Mechanistic studies revealed that the adhesion and invasion capacities of 269ΔSTM0343ΔCsgB decreased by 29.41% and 68.58%, respectively, compared to 269ΔSTM0343. …”
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HDST 技术应用于卵巢癌新辅助化疗中的效果分析 by 饶群仙, 韦苑, 林少丹, 彭永排, 林荣春, 何远桥, 林仲秋, 陈青松

“…HDST    结果与临床疗效间一致性较好（Kappa=1.000，P<0.05），灵敏度、特异度和正确指数为100%；患者Fagotti 评分变化和HDST 有效率间存在显著正相关（rs=0.678，P<0.05），而CA125、HE4 总下降率和HDST 有效率间无相关（P>0.05）。…”
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Exploring Disparities in Gill Physiological Responses to NaHCO₃-Induced Habitat Stress in Triploid and Diploid Crucian Carp (<i>Carassius auratus</i>): A Comprehensive I... by Shicheng Han, Lin Han, Fangying Yuan, Wenzhi Liu, Jing Wang, Xiaofeng Jin, Yanchun Sun

“…Diploid crucian carp exhibit superior antioxidant and immune capacities compared to triploid counterparts, while also displaying reduced inflammatory responses in vivo. …”
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Development and validation of a novel artificial intelligence algorithm for precise prediction the postoperative prognosis of esophageal squamous cell carcinoma by Zichen Wang, Zhihan Xiao, Tongyu Zhang, Meiyou Lu, Hai Li, Jing Cao, Jianan Zheng, Yichan Zhou, Juncheng Dai, Cheng Wang, Liang Chen, Jing Xu

“…In addition, the top-ranking CTG HENMT1 encodes 2’-O-methyltransferase of piRNAs that was confirmed positively correlated with the proliferation capacity of ESCC cells. Then we systematically screen piRNAs associated with esophageal carcinoma based on GWAS, eQTL-piRNA, and i2OM databases, and successfully discovered 8 piRNAs potentially regulated by HENMT1. …”
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UHPLC-QTOF-MS/MS profiling, molecular networking, and molecular docking analysis of Gliricidia sepium (Jacq.) Kunth. ex. Walp. stem ethanolic extract and its gastroprotective effec... by Aya A. Wafaey, Seham S. El-Hawary, Osama G. Mohamed, Sahar S. Abdelrahman, Alaa M. Ali, Ahmed A. El-Rashedy, Mohamed F. Abdelhameed, Farid N. Kirollos

“…Additionally, it enhanced superoxide dismutase and inhibitor of nuclear factor kappa B alpha levels, while lowering the expression of inducible nitric oxide synthase. …”
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Gedunin Mitigates <i>Cutibacterium acnes</i>-Induced Skin Inflammation by Inhibiting the NF-κB Pathway by Ju Kyoung Sim, Ye Ji Heo, Jin Hak Shin, Seon Sook Kim, Su Ryeon Seo

“…Mechanistic studies focused on the nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathways, along with the NOD-like receptor pyrin domain-containing 3 (NLRP3) inflammasome. …”
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Comparative Analysis of Meat Quality and Hindgut Microbiota of Cultured and Wild Bighead Carp (<i>Hypophthalmichthys nobilis</i>, Richardson 1845) from the Yangtze River Area by Abdullateef Mukhtar Muhammad, Chang Yang, Bo Liu, Cunxin Sun, Linghong Miao, Xiaochuan Zheng, Liangkun Pan, Dong Xia, Qun-Lan Zhou

“…The results showed that wild bighead carp muscle had significantly higher total saturated fatty acid (∑SFA) and total ω − 3 polyunsaturated fatty acid (∑n − 3 PUFA) content and water-holding capacity and lower lipid, histidine, and total ω − 6 polyunsaturated fatty acid (∑n − 6 PUFA) content than cultured bighead carp, while the muscle texture was not significantly different between the two groups, with the exception of the resilience. …”
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TiO₂ Nanosphere/MoSe₂ Nanosheet-Based Heterojunction Gas Sensor for High-Sensitivity Sulfur Dioxide Detection by Lanjuan Zhou, Chang Niu, Tian Wang, Hao Zhang, Gongao Jiao, Dongzhi Zhang

“…The experimental results suggest that the enhanced SO₂ adsorption capacity of the TiO₂/MoSe₂ composite can be attributed to the formation of an n-n heterojunction and the unique microstructural features of TiO₂/MoSe₂. …”
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A Novel Stacked Model for Classification of Vocal Cord Paralysis Over Imbalanced Vocal Data by K. Jayashree Hegde, K. Manjula Shenoy, K. Devaraja

“…In addition, the proposed model&#x2019;s robustness and trustworthiness are proven by the False Discovery Rate of 0.07142, Cohen Kappa of 0.82105, Mathew&#x2019;s Correlation coefficient (MCC) of 0.83452, and F1-score 0.91005. …”
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FSTL1 aggravates high glucose-induced oxidative stress and transdifferentiation in HK-2 cells by Baoyuan Zhang, Hang Geng, Kai Zhao, Moussa Omorou, Shuang Liu, Zhihui Ye, Fanting Zhang, Haiyan Luan, Xuesong Zhang

“…We then analyzed proliferation, oxidative stress, transdifferentiation, cell migration, and the nuclear factor kappa-B (NF-κB) signaling pathway potentially involved in FSTL1 effects. …”
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Initial use of supplementary oxygen for trauma patients: a systematic review by Trine Grodum Eskesen, Josefine Stokholm Baekgaard, Jacob Steinmetz, Lars S Rasmussen

“…Two independent reviewers screened and identified studies and extracted data from included studies.Results 6142 citations were screened with an inter-rater reliability (Cohen’s kappa) of 0.88. One interventional trial of intubated trauma patients was included. 68 trauma patients were randomised to receive an FiO2 of 0.80 (intervention group) or 0.50 (control group) during mechanical ventilation (first 6 hours). …”
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Time-series forest age estimation in Xinjiang based on forest disturbance and recovery detection by Lili Zhai, Mei Zan, Mao Ye, Jia Zhou, Cong Xue, Shunfa Yang, Yuntong Liu

“…The age of a forest serves as a critical indicator of both its carbon stock and its capacity for carbon volume within forest ecosystems. …”
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Strain-specific effect of Streptococcus thermophilus consumption on host physiology by Peng Yu, Yang Jiang, Yuqi Pan, Min Guo, Bo Yang, Xiaoming Liu, Jianxin Zhao, Hao Zhang, Wei Chen

“…Comparative genomic analysis revealed that the four S. thermophilus strains belonged to different branches in the phylogenetic tree, and DYNDL13-4 and DQHXNQ38M61 had more genes involved in carbohydrate metabolism, amino acid metabolism, membrane transport, and signal transduction, which may confer the capacity of nutrient utilization and gastrointestinal adaptation of the strains and be associated with their strong regulation in host. …”
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AI-assisted diagnosis of vulvovaginal candidiasis using cascaded neural networks by Zhongxiao Wang, Ruliang Wang, Haichun Guo, Qiannan Zhao, Huijun Ren, Jumin Niu, Ying Wang, Wei Wu, Bingbing Liang, Xin Yi, Xiaolei Zhang, Shiqi Xu, Xianling Dong, Liqun Wang, Qinping Liao

“…The consistency rates and Cohen’s kappa coefficients between experts’ interpretations of microscopic digital images and microscopic examination under eyepiece exceeded 93% and 0.83 for the three different morphologic states of yeast. …”
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Identification and Validation of the Pyroptosis-Related Hub Gene Signature and the Associated Regulation Axis in Diabetic Keratopathy by Yi Cui, Li Wang, Wentao Liang, Li Huang, Shuting Zhuang, Hong Shi, Nuo Xu, Jianzhang Hu

“…Gene Set Enrichment Analysis highlighted significant enrichment of the NOD-like receptor, Toll-like receptor, and NF-kappa B signaling pathways. Intersection of DEGs and pyroptosis-related datasets showed 33 differentially expressed pyroptosis-related genes (DEPRGs) associated with pathways such as IL-17, NOD-like receptor, TNF, and Toll-like receptor signaling. …”
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Lactococcus lactis D4 Decreases NF-κB and α-SMA in Rat Models of Obstructive Jaundice by Avit Suchitra, Alvarino Alvarino, Eryati Darwin, Harnavi Harun, Muhammad Iqbal Rivai, Ade Sukma

“…Some inflammatory mediators like nuclear factor kappa B (NF-κB), alpha-smooth muscle actin (α-SMA), and interleukin-6 (IL-6) are important in this process. …”
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On the substrate turnover rate of NBCe1 and AE1 SLC4 transporters: structure-function considerations by Alexander Pushkin, Liyo Kao, Hristina R. Zhekova, Rustam Azimov, Natalia Abuladze, Xuesi M. Shao, D. Peter Tieleman, Ira Kurtz, Ira Kurtz

“…Knowledge of a transporter’s TOR allows comparison of the transport capacity of various transporters at the molecular level as well as the total transport per cell and whole organ levels. …”
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