Fibrocyte enrichment and myofibroblastic adaptation causes nucleus pulposus fibrosis and associates with disc degeneration severity by Yi Sun, Yan Peng, Zezhuo Su, Kyle, K. H. So, Qiuji Lu, Maojiang Lyu, Jianwei Zuo, Yongcan Huang, Zhiping Guan, Kenneth M. C. Cheung, Zhaomin Zheng, Xintao Zhang, Victor Y. L. Leung

“…We found that disc degeneration severity is associated with an enrichment of fibrocyte phenotype, characterized by CD45 and collagen I dual positivity, and expression of myofibroblast marker α-smooth muscle actin. Refined clustering and classification distinguished the fibrocyte-like populations as subtypes in the NP cells - and immunocytes-clusters, expressing disc degeneration markers HTRA1 and ANGPTL4 and genes related to response to TGF-β. …”
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Ginsenoside Rg1 Regulates SIRT1 to Ameliorate Sepsis-Induced Lung Inflammation and Injury via Inhibiting Endoplasmic Reticulum Stress and Inflammation by Qian-Lu Wang, Lei Yang, Yue Peng, Min Gao, Ming-Shi Yang, Wei Xing, Xian-Zhong Xiao

“…Western blotting was used to examine the activation of inflammatory pathways and ER stress marker proteins in both cells and mouse lung tissues. …”
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Estimation of cytoprotective effect of bismuth tripotassium dicitrate on gastric mucosa at <i>H. pylori</i> eradication and long-term drug intake by A. V. Kononov, S. I. Mozgovoi, L. B. Rybkina, S. S. Bunova, A. G. Shimanskaya

“…Borders of a generative zone were determined by the presence of myofibroblasts surrounding glandular epithelium which were identified immunohistochemically, using smooth-muscle actin as a marker. Cells with damaged DNA were revealed by immunehistochemical detection of Р53 protein.Results. …”
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Measurement and Analysis of Gait Pattern during Stair Walk for Improvement of Robotic Locomotion Rehabilitation System by Sang-Eun Park, Ye-Ji Ho, Min Ho Chun, Jaesoon Choi, Youngjin Moon

“…The measured marker data were converted into joint kinematic data by using an algorithm that included resampling and normalization. …”
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DNA metabarcoding of benthic algae and associated eukaryotes from Lake Baikal in the face of rapid environmental changes by Yu. S. Bukin, L. S. Kravtsova, T. E. Peretolchina, A. P. Fedotov, A. E. Tupikin, M. R. Kabilov, D. Yu. Sherbakov, E. V. Mincheva

“…About 15 thousand reads of the 18S rRNA marker were obtained by applying NGS (next-generation sequencing). …”
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Assessment of hypoxia status in a rat chronic liver disease model using IVIM and T1 mapping by Wenlu Dong, Longyang Xiao, Ziwei Luo, Haiyang Yu, Lili Wang, Yuanxiang Gao, Zhiming Li

“…Liver specimens were subjected to immunohistochemical staining for the exogenous hypoxia marker pimonidazole and the endogenous hypoxia marker HIF-1α and scored semi-quantitatively. …”
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Systemic immune-inflammation index: Unveiling the diagnostic potential in ulcerative colitis through a comprehensive systematic review and meta-analysis by Anas Elgenidy, Omar Alomari, Tasbih Emad, Sara K. Kamal, Islam E. Al Ghanam, Aya Sherif, Mohammed Al-mahdi Al-kurdi, Abdallah A. Helal, Yusof Mohamed Omar, Mohamed Rafiek Ramadan

“…Conclusion: Our meta-analysis reveals that the SII holds significant promise as a non-invasive marker for assessing the activity and severity of UC. …”
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Tumor Necrosis Factor Receptor Superfamily, Member 1B Haplotypes Increase or Decrease the Risk of Inflammatory Bowel Diseases in a New Zealand Caucasian Population by Lynnette R. Ferguson, Dug Yeo Han, Claudia Huebner, Ivonne Petermann, Murray L. Barclay, Richard B. Gearry, Alan McCulloch, Pieter S. Demmers

“…We conclude that carrying a 3-marker haplotype in the TNSFRSF1B gene may increase (e.g., haplotype of GGC was 2.9-fold more in the CD or UCpatients) or decrease (e.g., TGT was 0.47-fold less in UC patients) the risk of IBD in a New Zealand Caucasian population.…”
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Diversity and Conservation Status of Large Mammals in Ghamot National Park, Azad Jammu and Kashmir, Pakistan by Muhammad Jahangeer, Siddique Muhammad, Muhammad Shakeel, Mir Muhammad Saleem, Ali Usman, Hussain Abid

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A Novel Oxidative Stress Mediator in Acute Appendicitis: Thiol/Disulphide Homeostasis by Sefa Ozyazici, Faruk Karateke, Umit Turan, Adnan Kuvvetli, Huseyin Kilavuz, Burak Karakaya, Pınar Ozaltun, Murat Alısık, Ozcan Erel

“…To investigate the role of a novel oxidative stress marker, thiol/disulphide homeostasis, in patients diagnosed with acute appendicitis (AA). …”
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The Carcinoma–Stromal Ratio of Colon Carcinoma Is an Independent Factor for Survival Compared to Lymph Node Status and Tumor Stage by Wilma E. Mesker, Jan M. C. Junggeburt, Karoly Szuhai, Pieter de Heer, Hans Morreau, Hans J. Tanke, Rob A. E. M. Tollenaar

“…We have evaluated, for the primary tumor, if the carcinoma-percentage (CP), as a derivative from the carcinoma-stromal ratio, can be applied as a candidate marker to identify patients for adjuvant therapy. …”
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Predicting bursal-side supraspinatus tendon tears with the acromioclavicular angle by Nadhaporn Saengpetch, Jaturong Bamrungchaowkasem, Niyata Chitrapazt, Pinkawas Kongmalai

“…Conclusion: The AC angle, particularly when measured on MRI, may serve as a valuable diagnostic marker for identifying isolated bursal-side supraspinatus tendon tears. …”
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Effects of Lemon Beverage Containing Citric Acid with Calcium Supplementation on Bone Metabolism and Mineral Density in Postmenopausal Women: Double-Blind 11-Month Intervention Stu... by Hiromi Ikeda, Tadayuki Iida, Masanori Hiramitsu, Takashi Inoue, Satomi Aoi, Miho Kanazashi, Fumiko Ishizaki, Toshihide Harada

“…The LECA group also showed significant decreases in concentrations of tartrate-resistant acid phosphatase 5b (TRACP-5b), a bone resorption marker, and bone alkaline phosphatase (BAP) as compared to the other groups, as well as a significant decrease in concentration of osteocalcin (OC), a bone formation marker, as compared to the LE group. …”
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Apoptosis antagonizing transcription factor expression and its validation as a potential diagnostic and prognostic biomarker in oral squamous cell carcinoma by Ainiwaerjiang Abudourousuli, Zumulaiti Aierken, Hasiyati Mamuti, Tuxunayi Yimamu, Chengli Da

“…High AATF levels serve as an independent marker of poor OS and DSS. These findings support AATF as a valuable prognostic biomarker and a potential therapeutic target in OSCC, warranting further investigation.…”
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Combination of rapamycin and adipose-derived mesenchymal stromal cells enhances therapeutic potential for osteoarthritis by Damien Veret, Gautier Tejedor, Esther Perez, Alison Chomette, Maylis Farno, Rosanna Ferreira-Lopez, Louis Dagneaux, Yves-Marie Pers, Christian Jorgsensen, Claire Gondeau, Jean-Marc Brondello

“…Results In OA chondrocytes, rapamycin reduced the senescence marker p15INK4B and the fibrosis marker COL1A1 without affecting the expression of the master chondrogenic markers SOX9 and COL2. …”
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B Cell Activation, Differentiation, and Their Potential Molecular Mechanisms in Osteoarthritic Synovial Tissue by Lu P, Li Y, Yang S, Yao H, Tu B, Ning R

“…Specifically, the proportion of activated CD86+ B cells and the differentiation marker HLA-DR+ increased with disease severity, whereas the proportion of the differentiation marker IgM decreased. …”
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Mesenchymal Stem/Stromal Cells Derived from Induced Pluripotent Stem Cells Support CD34pos Hematopoietic Stem Cell Propagation and Suppress Inflammatory Reaction by Mohsen Moslem, Irina Eberle, Iuliia Weber, Reinhard Henschler, Tobias Cantz

“…In direct comparison to BM-MSCs our iPSC-MSCs exhibited a similar surface marker expression profile but shorter doubling times without reaching senescence within 20 passages. …”
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Gum Arabic (Acacia Senegal) Augmented Total Antioxidant Capacity and Reduced C-Reactive Protein among Haemodialysis Patients in Phase II Trial by Nour Elkhair Ali, Lamis AbdelGadir Kaddam, Suad Yousif Alkarib, Babikir Gabir Kaballo, Sami Ahmed Khalid, Abdalazim Higawee, Alaa AbdElhabib, Alaa AlaaAldeen, Aled O. Phillips, Amal Mahmoud Saeed

“…Total antioxidant capacity (TAC) and oxidative stress marker malondialdehyde (MDA) levels were measured before and after GA intake. …”
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Molecular Identification of Mycobacterium Species of Public Health and Veterinary Importance from Cattle in the South State of México by Adrian Zaragoza Bastida, Nallely Rivero Pérez, Benjamín Valladares Carranza, Keila Isaac-Olivé, Pablo Moreno Pérez, Horacio Sandoval Trujillo, Ninfa Ramírez Durán

“…Thirteen strains isolated from nasal exudates amplified the 100 bp molecular marker and were identified as M. neoaurum (six strains), M. parafortuitum (four strains), M. moriokaense (two strains), and M. confluentis (one strain). …”
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High Dimensionality Reduction and Immune Phenotyping of Natural Killer and Invariant Natural Killer Cells in Latent Tuberculosis-Diabetes Comorbidity by Gokul Raj Kathamuthu, Nathella Pavan Kumar, Kadar Moideen, Pradeep A. Menon, Subash Babu

“…However, the role of NK and iNKT cells expressing cytokines, cytotoxic, and immune markers in latent tuberculosis (LTB), diabetes mellitus (DM), or preDM (PDM) and nonDM (NDM) comorbidities is not known. …”
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