-
6221
Effects of a liquefied petroleum gas stove and fuel intervention on head circumference and length at birth: A multi-country household air pollution intervention network (HAPIN) tri...
Published 2025-01-01“…Background: Air pollution may impair child growth and cognitive development, with potential markers including birth length and head circumference. …”
Get full text
Article -
6222
Effects of Carbonate Alkalinity on Antioxidants, Immunity and Intestinal Flora of <i>Penaeus vannamei</i>
Published 2024-12-01“…The activity of antioxidant enzymes was determined by enzyme markers, and then the intestinal microorganisms of <i>Penaeus vannamei</i> were analyzed by high-throughput sequencing technology. …”
Get full text
Article -
6223
N-acetylcysteine increased the growth performance of Leuciscus waleckii by improving mitochondrial function, enhancing antioxidant and anti-inflammatory, and inhibiting apoptosis i...
Published 2025-03-01“…NAC supplementation upregulates the mRNA expression of Claudin-3, Claudin-f, ZO-1, and Occludin-a and reduces intestinal permeability-related markers, thereby maintaining intestinal physical barrier function. …”
Get full text
Article -
6224
Sex differences in epigenetic ageing for older people living with HIVResearch in context
Published 2025-03-01“…We found epigenetic age acceleration associated with plasma proteomic markers involved in inflammation, senescence, immune regulation, kidney function, and tissue homoeostasis (p < 0.0001). …”
Get full text
Article -
6225
Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy
Published 2021-02-01“…The therapeutic use of these Nb-Fc fusion proteins was evaluated, either as monotherapy or as combination therapy with anti-programmed cell death protein-1 (anti-PD-1), in both the LLC-OVA and MC38 mouse models.Results We were able to discern two ti-Treg populations, one of which is characterized by the unique expression of Ccr8 in conjunction with Treg activation markers. Ccr8 is also expressed by dysfunctional CD4+ and CD8+ T cells, but the CCR8 protein was only prominent on the highly activated and strongly T-cell suppressive ti-Treg subpopulation of mouse and human tumors, with no major CCR8-positivity found on peripheral Tregs. …”
Get full text
Article -
6226
Unraveling the immunological landscape and gut microbiome in sepsis: a comprehensive approach to diagnosis and prognosisResearch in context
Published 2025-03-01“…In addition, T cell phenotypes within adaptive immunity are correlated with sepsis severity and may serve as reliable prognostic markers. Funding: This project was supported by the National Key R&D Program of China (2023YFC2307600, 2021YFA1301000), Shanghai Municipal Science and Technology Major Project (2023SHZDZX02, 2017SHZDZX01), Shanghai Municipal Technology Standards Project (23DZ2202600).…”
Get full text
Article -
6227
Immunomodulatory Effects of Combination Therapy with Bushen Formula plus Entecavir for Chronic Hepatitis B Patients
Published 2019-01-01“…Biochemical assessment, viral load quantitation, and HBV markers were tested. Chinese medicine symptom complex score was evaluated and recorded as well. …”
Get full text
Article -
6228
The Potential Proallergenic Activity of Tranzschelia pruni-spinosae and Phragmidium rubi-idaei in vitro Studies
Published 2025-01-01“…Immunofluorescence techniques were employed to assess cell integrity markers.Results: Extracts from T. pruni-spinosae and P. rubi-idaei significantly stimulated the production of proinflammatory cytokines IL-1β and GM-CSF in both cell lines, all of which are associated with the development of allergic responses. …”
Get full text
Article -
6229
Serum hsa-miR-22-3p, hsa-miR-885-5p, Lipase-to-Amylase Ratio, C-Reactive Protein, CA19-9, and Neutrophil-to-Lymphocyte Ratio as Prognostic Factors in Advanced Pancreatic Ductal Ade...
Published 2025-01-01“…The selected miRNAs and LAR were not confirmed as reliable prognostic markers in PC.…”
Get full text
Article -
6230
Poly (ADP-ribose) (PAR) levels in Peripheral Blood Mononuclear Cells (PBMC) during peri-implantation and early pregnancy in buffalo cows
Published 2023-11-01“…Since its involvement in the blastocyst implantation has been hypothesized and considered the importance of markers for predicting pregnancy success, with this study, we wanted to evaluate dynamic changes in PAR levels during peri-implantation and early pregnancy in peripheral blood mononuclear cells (PBMCs) in buffalo species. …”
Get full text
Article -
6231
Cocktail of Ropivacaine, Morphine, and Diprospan Reduces Pain and Prolongs Analgesic Effects after Total Knee Arthroplasty: A Prospective Randomized Controlled Trial
Published 2024-01-01“…The primary outcomes were the levels of inflammatory markers C-reactive protein (CRP) and interleukin-6 (IL-6), pain visual analog scale (VAS) scores, opioid consumption, range of motion (ROM), functional tests, and sleeping quality. …”
Get full text
Article -
6232
-
6233
Exploring the clinical value of procalcitonin, c-reactive protein, white blood cell count, and neutrophil-to-lymphocyte ratio in the early diagnosis of bloodstream infections in ch...
Published 2025-01-01“…Abstract Backgroud In the diagnosis of bloodstream infections (BSI) in children, compared to the gold standard of blood culture, markers in the blood offer advantages such as rapid results and cost-effectiveness. …”
Get full text
Article -
6234
Monocyte STAT1 phosphorylation and treatment response of JAK inhibitors in chronic nonbacterial osteomyelitis
Published 2025-01-01“…The early diagnosis and management are challenging due to the lack of reliable diagnostic markers and the occasional intractable cases despite conventional anti-inflammatory treatments. …”
Get full text
Article -
6235
α-Methyl-Tryptophan Inhibits SLC6A14 Expression and Exhibits Immunomodulatory Effects in Crohn’s Disease
Published 2025-01-01“…The α-MT treatment group also exhibited reduced levels of cytokines involved in T cell differentiation (IFN-γ and TNF-α) and the expression of immune cell surface markers CXCR-3 and LAG-3. Flow cytometry analysis revealed a significant increase in the infiltration of CD4+ and CD8+ T cells in the DSS-treated group compared to the control group. …”
Get full text
Article -
6236
Effects of biologic therapy on novel indices of lung inhomogeneity in patients with severe type-2 high asthma
Published 2025-02-01“…Here, we assessed changes in lung inhomogeneity in patients with type-2 high asthma treated with biological therapy and explored the relationship between inhomogeneity measures and conventional asthma disease markers.Methods This was an observational study of 91 severe type-2 high asthma patients recruited from a tertiary asthma clinic, of whom 67 subsequently started anti-IL5 or anti-IL5R biologics. …”
Get full text
Article -
6237
Are we serologically prepared against an avian influenza pandemic and could seasonal flu vaccines help us?
Published 2025-02-01“…Importantly, HPAI H5N1 viruses with genetic markers of adaptation to mammals have been detected. …”
Get full text
Article -
6238
Potential diagnostic tools for intensive care unit acquired weakness: A systematic review
Published 2025-06-01“…In the included studies, the gold standard for intensive care unit-acquired weakness diagnosis include the Medical Research Council score, muscle biopsy and electrophysiologic testing, potential diagnostic tools include the manual muscle test, electrophysiologic testing, imaging, serum inflammatory markers, neuromuscular ultrasound, and other parameters. …”
Get full text
Article -
6239
The effects of altitude training on hormonal response in professional cyclists
Published 2025-01-01“…Discussion/Conclusion In summary, this study was the first to monitor hormonal markers over 7 weeks before, during, and after a 3-week altitude training camp in a large cohort of professional cyclists. …”
Get full text
Article -
6240
Prevalence and factors associated with potential clinically significant drug-drug interactions in patients with cardiovascular diseases at hospital admission
Published 2024-12-01“…The most common interventions regarding identified DDIs included exclusion one of the drugs, dose adjustment, increased monitoring of signs of bleeding, cardiac disorders, hypoglycemia, CNS depression and rhabdomyolysis, blood pressure, markers of renal function and electrolyte status. …”
Get full text
Article