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5461
Correlations of inflammatory processes caused by cerebral stroke with the outcome of the disease
Published 2023-10-01“…Elevated inflammatory markers and other prognostic factors are directly associated with higher rates of in-hospital complications such as pneumonia, urinary tract infection, and unfavorable stroke outcomes. …”
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5462
Exploring Inflammatory Changes in the Peripheral Blood of Type 2 Diabetes Mellitus in China
Published 2025-02-01“…This study aimed to thoroughly investigate the fluctuation of inflammatory markers in the peripheral blood of patients with T2DM, which are rarely reported.Methods: Peripheral blood samples from patients with T2DM and healthy individuals, as well as their clinical information, were collected at the Second Affiliated Hospital of Soochow University. …”
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5463
sCD40L Is Increased and Associated with the Risk of Gestational Diabetes Mellitus in Pregnant Women with Isolated TPOAb Positivity
Published 2022-01-01“…Soluble CD40 ligand (sCD40L) and soluble interleukin-2 receptor (sCD25) are abnormally expressed in autoimmune diseases and are reliable markers of inflammation. The purpose of this study was to evaluate sCD40L and sCD25 in early pregnancy and investigate their correlation with GDM and TPOAb. …”
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5464
Status of the Multidrug Resistance-1 Gene of Plasmodium falciparum in Four Malaria Epidemiological Strata, Two Decades after the Abolition of Chloroquine as First-Line Treatment fo...
Published 2023-01-01“…Four hundred P. falciparum monoinfected samples, 100 per study area, were amplified by nested PCR, and allele-specific restriction analysis of Pfmdr1 gene molecular markers was performed. Fragments were analyzed using a 3% ethidium bromide-stained agarose gel. …”
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5465
Pituitary adenoma: literature review and association with TAS2R16 (rs978739, rs1357949) gene polymorphisms
Published 2023-10-01“…Considering the influence of environmental factors and genetic alterations that affect the occurrence of PA, new genetic markers can be searched to detect this disease. One of the risk factors contributing to the development of PA and its aggressiveness is alcohol consumption. …”
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5466
Combination therapy of low-dose radiotherapy and immunotherapy in advanced metastatic nasopharyngeal carcinoma: a case report and literature review
Published 2025-01-01“…Conclusion The combination of chemotherapy and LDRT with aspirin and human granulocyte macrophage colony-stimulating factor improved the disease state of advanced NPC cancer, effectively reducing the level of tumor markers, enhanced the immune function without significant adverse reactions.…”
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5467
Dysregulation of Metabolic Peptides Precedes Hyperinsulinemia and Inflammation Following Exposure to Rotenone in Rats
Published 2025-01-01“…The potential implications of these findings are vast, given that monitoring these markers in the blood could not only provide a crucial tool for assessing the extent of exposure and its relevance to obesity and inflammation but could also open new avenues for future research and potential therapeutic strategies.…”
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5468
Decreased Gray Matter Volume in the Frontal Cortex of Migraine Patients with Associated Functional Connectivity Alterations: A VBM and rs-FC Study
Published 2022-01-01“…However, the pathophysiology and imaging markers specific for migraine pathologies are not well understood. …”
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5469
The problem of conservation of gene pools of domesticated animals
Published 2017-07-01“…Within breeds of the same species or within one species it is possible to spot the ancient or the most estranged from the “protogene pool” groups of animals and, thus, to use these data in the breeding strategy aimed at the preservation of animal forms close to the ancestral form. Using various DNA markers, methods of genomic and genetic breeding in nature conservation and genetic selection of domesticated species provides an opportunity to obtain data on the genetic potential (value, originality) of the breed, which is important for scientific justification of its preservation.…”
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5470
Endothelial injury is one of the risk factors for the progression of vascular calcification in patients receiving maintenance dialysis
Published 2025-12-01“…We also detected the markers of endothelial injury [E-selectin and soluble intercellular adhesion molecule-1 (sICAM-1)]. …”
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5471
Efficacy and Safety of Bicyclol Treatment for Non-Alcoholic Fatty Liver Disease: Results of a Cohort Study
Published 2018-09-01“…Bicyclol therapy in NAFLD is accompanied by positive dynamics of inflammation activity markers, insulin resistance and lipid spectrum, which suggests a positive dynamics of the stages of liver fibrosis and steatosis.…”
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5472
The feasibility of using liver function indices and FibroScan in combination to predict the occurrence of anti-tuberculosis drug-induced liver injury in Patients with liver disease
Published 2025-01-01“…Results: Patients who developed DILI showed significantly higher levels of ALT, AST, total bilirubin, GGT, and LSM, with strong positive correlations between these markers and DILI occurrence. Logistic regression analysis revealed elevated ALT, AST, TBIL, and GGT were strongly associated with an increased likelihood of DILI. …”
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5473
Older People's Perceptions of Well-Being
Published 2025-01-01“…In the semantic group “emotions” in the structure of ideas about well-being in elderly people, emotions of greater intensity prevail over emotions of lesser intensity. Markers of negative emotions in the structure of ideas about well-being are absent.…”
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5474
Laminin-5 γ2 Chain Expression Correlates with Unfavorable Prognosis in Colon Carcinomas
Published 2001-01-01“…As there is considerable need for reliable invasion and prognostic markers we evaluated the correlation of laminin-5 γ2 chain expression with clinicopathologic parameters and patient survival in 93 primary colon carcinomas. …”
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5475
Progenitor Hematopoietic Cells Implantation Improves Functional Capacity of End Stage Coronary Artery Disease Patients with Advanced Heart Failure
Published 2016-01-01“…Flow cytometry and cell surface markers were used to characterize PHC. The PHC were delivered retrogradely via sinus coronarius. …”
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5476
Hepatic Stellate Cell-Derived Microvesicles Prevent Hepatocytes from Injury Induced by APAP/H2O2
Published 2016-01-01“…Results showed that (1) HSC-MVs derived from LX-2 and HST-T6 were positive to CD90 and annexin V surface markers; (2) HSC-MVs dose-dependently improved the viability of hepatocytes in both injury models; (3) HSC-MVs dose-dependently inhibited the APAP/H2O2 induced hepatocytes apoptosis and activated caspase-3 expression and leakage of LDH, ALT, and AST. …”
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5477
<i>Bacillus anthracis</i> strain differentiation based on SNP and VNTR loci
Published 2022-10-01“…Modern methods of molecular biology make it possible to detect a number of genetic markers suitable for indicating and differentiating the strains of B. anthracis, including the loci arranged as variable number tandem repeats (VNTRs) and SNPs, one nucleotide-sized differences in the DNA sequence of the loci being compared. …”
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5478
Spatial genetic characterization of the red fox (Vulpes vulpes) in the area between the Alps and the Central Dinaric Mountains
Published 2024-11-01“…In this study, we used a set of microsatellite markers for the comparative genetic analysis of red fox populations from two countries. …”
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5479
Biotin's protective effects against nicotine withdrawal-induced anxiety and depression: Mechanistic insights into serotonin, inflammation, BDNF, and oxidative stress in male rats
Published 2025-06-01“…We also performed biochemical analyses to measure serotonin levels, monoamine oxidase A activity, brain neurotrophic factor concentration, and markers of oxidative stress. Results: The results demonstrated that nicotine withdrawal intensifies behavioral symptoms of anxiety and depression by disrupting serotonin metabolism, triggering inflammatory responses, and upsetting the balance of oxidative stress. …”
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5480
Comprehensive analysis of publications concerning combinations of immunotherapy and targeted therapies for hepatocellular carcinoma: a bibliometric study
Published 2025-02-01“…Early research primarily focused on angiogenesis, dendritic cells, and expression markers, while recent trends have shifted towards phase III trials, adverse reactions, and checkpoint inhibitors, underscoring the field’s dynamic progression.ConclusionFuture research will expand on the pathological mechanisms underlying these therapies and novel interventions and combination strategies. …”
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