Betaine enhances SCAPs chondrogenic differentiation and promotes cartilage repair in TMJOA through WDR81 by Meiyue Wang, Zejie Wu, Xiaoyu Zheng, Yishu Huang, Yizhou Jin, Jiaxin Song, Wanzhen Lei, Hua Liu, Riyue Yu, Haoqing Yang, Runtao Gao

“…The chondrogenic differentiation potential was assessed using Alcian Blue staining, Sirius Red staining and the main chondrogenic markers. In vivo cartilage regeneration effects were evaluated by the rat TMJOA model. …”
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Isoniazid and Rifampicin Produce Hepatic Fibrosis through an Oxidative Stress-Dependent Mechanism by Ayan Biswas, Suman Santra, Debasree Bishnu, Gopal Krishna Dhali, Abhijit Chowdhury, Amal Santra

“…Progressive increase in markers of hepatic stellate cell (HSC) activation associated with changes in matrix turnover was observed between 12 and 24 weeks of INH-RMP treatment along with the elevation of liver collagen content and significant periportal fibrosis. …”
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Albuminuria Is Associated with Left Ventricular Hypertrophy in Patients with Early Diabetic Kidney Disease by Nan Wu, Weiwei Zhao, Kuanping Ye, Yintao Li, Min He, Bin Lu, Renming Hu

“…Left ventricular hypertrophy (LVH) and albuminuria are both markers for cardiovascular diseases (CVDs) in patients with type 2 diabetes mellitus (T2DM). …”
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The Effects of Vitamin D on Gentamicin-Induced Acute Kidney Injury in Experimental Rat Model by Ender Hur, Alev Garip, Asuman Camyar, Sibel Ilgun, Melih Ozisik, Sena Tuna, Murat Olukman, Zehra Narli Ozdemir, Eser Yildirim Sozmen, Sait Sen, Fehmi Akcicek, Soner Duman

“…Blood urea and creatinine levels and urine tubular injury markers were measured. Renal histology was semiquantitatively assessed. …”
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Desmoplastic Small Round Cell Tumor of Stomach by Ahmed Abu-Zaid, Ayman Azzam, Asma AlNajjar, Hussa Al-Hussaini, Tarek Amin

“…Histopathological examination revealed coexpression of mesenchymal, epithelial, and neural markers. The characteristic chromosomal translocation (t(11; 22)(p13; q12)) was demonstrated on fluorescence in situ hybridization (FISH) technique. …”
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Induced hepatocyte-like cells derived from adipose-derived stem cells alleviates liver injury in mice infected with Echinococcus Multilocularis by Hui Liu, Xiaojuan Bi, Ning Yang, Xue Zhang, Bingbing Fang, Nuerbaiti Kusuman, Wenmei Ma, Jing Li, Jin Chu, Li Sun, Liang Li, Guodong Lü, Renyong Lin

“…The expression of hepatocyte lineage markers was assessed and iHEPs function was evaluated by Periodic acid-Schiff staining. iHEPs were intravenously transplanted into mice infected with Echinococcus multilocularis. …”
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Prolonged Cardiopulmonary Bypass Time-Induced Endothelial Dysfunction via Glypican-1 Shedding, Inflammation, and Matrix Metalloproteinase 9 in Patients Undergoing Cardiac Surgery by Shiyi Li, Katherine V. Nordick, Iván Murrieta-Álvarez, Randall P. Kirby, Rishav Bhattacharya, Ismael Garcia, Camila Hochman-Mendez, Todd K. Rosengart, Kenneth K. Liao, Nandan K. Mondal

“…However, after the end of the CPB, all three markers showed significant elevation in the prolonged CPB group compared to the normal CPB group. …”
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Oncogenic PIK3CA corrupts growth factor signaling specificity by Ralitsa R Madsen, Alix Le Marois, Oliwia N Mruk, Margaritis Voliotis, Shaozhen Yin, Jahangir Sufi, Xiao Qin, Salome J Zhao, Julia Gorczynska, Daniele Morelli, Lindsay Davidson, Erik Sahai, Viktor I Korolchuk, Christopher J Tape, Bart Vanhaesebroeck

“…This features live-cell imaging of PI3K/AKT activity reporters and multiplexed CyTOF measurements of PI3K/AKT and RAS/ERK signaling markers over time. Using this framework, we found that the PIK3CA H1047R oncogene was not a simple, constitutive activator of the pathway as often presented. …”
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Infection and HLA-G Molecules in Nasal Polyposis by Roberta Rizzo, Nicola Malagutti, Daria Bortolotti, Valentina Gentili, Antonella Rotola, Enrico Fainardi, Teresa Pezzolo, Claudia Aimoni, Stefano Pelucchi, Dario Di Luca, Antonio Pastore

“…These data highlight new aspects of polyposis aetiopathogenesis and suggest HPV-11 and HLA-G/IL-10 presence as prognostic markers in the follow-up of SNP-WoAD.…”
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iNOS-Produced Nitric Oxide from Cancer Cells as an Intermediate of Stemness Regulation by PARP-1 in Colorectal Cancer by María del Moral-Martinez, Paula Sánchez-Uceta, Ruben Clemente-Gonzalez, Sara Moreno-SanJuan, Jose D. Puentes-Pardo, Huda Khaldy, David Lopez-Perez, Javier Arnedo, Jorge Casado, Luis Martínez-Heredia, Angel Carazo, Josefa León

“…In CRC patients, iNOS expression correlated with the differentiation grade, and with a high expression of CSC markers, although only in wild-type p53 tumors, as previously found for PARP-1. …”
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Increased Expression of VEGF and CD31 in Postradiation Rectal Tissue: Implications for Radiation Proctitis by G. Karamanolis, I. Delladetsima, V. Kouloulias, K. Papaxoinis, I. Panayiotides, D. Haldeopoulos, K. Triantafyllou, N. Kelekis, S. D. Ladas

“…To investigate the expression of vascular endothelial growth factor (VEGF) and CD31 as angiogenetic markers in postradiation rectal tissue. Methods. Rectal mucosa biopsies from 11 patients who underwent irradiation for prostate cancer were examined immunohistochemically for the expression of VEGF and CD31 at three time settings—before, at the completion of, and 6 months after radiotherapy. …”
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Resistance of barley cultivars approved for use in Russia to harmful organisms and toxic aluminum ions by R. A. Abdullaev, B. A. Batasheva, N. V. Alpatieva, M. A. Chumakov, E. E. Radchenko, O. N. Kovaleva, O. V. Yakovleva

“…Barley cultivars distinguished for powdery mildew resistance were analyzed using molecular markers. In the laboratory, barley was screened for greenbug resistance. …”
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Behavior of Olive Genotypes Against Quick Decline Syndrome (QDS) Caused by <i>Xylella fastidiosa</i> subsp. <i>pauca</i> in Apulia by Mariangela Carlucci, Michele Antonio Savoia, Pompea Gabriella Lucchese, Valentina Fanelli, Isabella Mascio, Francesco Luigi Aurelio, Monica Marilena Miazzi, Andrea Pacifico, Cinzia Montemurro, Franco Nigro

“…These genotypes, which survived in heavily infected areas, showed varied responses to <i>Xfp</i>; some maintained low symptom severity with minimal bacterial presence (high or undetectable Cq values), while others exhibited increased bacterial loads yet remained asymptomatic or showed limited canopy desiccation. SSR markers were used to investigate the genetic relationships among these genotypes and other widespread Mediterranean cultivars, showing genetic similarity with the resistant ones such as the Albanian Kalinjot and the Greek Leucocarpa, as well as with local Apulian cultivars, highlighting the potential of local and Mediterranean olive germplasm for <i>Xfp</i> resistance. …”
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Impact of Cardiac Computed Tomographic Angiography Findings on Planning of Cancer Therapy in Patients with Concomitant Structural Heart Disease by Iyad N. Daher, Jose Banchs, Syed Wamique Yusuf, Elie Mouhayar, Jean-Bernard Durand, Gregory Gladish

“…A total of 80 patients underwent CCTA during the study period for the following indications (not mutually exclusive): cardiomyopathy of unknown etiology in 33 pts (41.3%), chest pain in 32 (40.0%), abnormal stress test in 16 (20.0%), abnormal cardiac markers in 8 (10.0%), suspected cardiac mass or thrombus in 7 (8.8%). …”
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TRAF1 Gene Polymorphism Correlates with the Titre of Gp210 Antibody in Patients with Primary Biliary Cirrhosis by Agnieszka Kempinska-Podhorodecka, Zakera Shums, Michał Wasilewicz, Ewa Wunsch, Malgorzata Milkiewicz, Dimitrios P. Bogdanos, Gary L. Norman, Piotr Milkiewicz

“…The association of TRAF1 polymorphisms with clinical features and autoantibody markers was also analyzed. Methods. We studied 179 PBC patients and 300 controls. …”
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The Levels of Tumor Necrosis Factor-Alpha and Interleukin-6 in Patients with Isolated Coronary Artery Ectasia by Mustafa Aydin, Ishak Ozel Tekin, Sait Mesut Dogan, Nesligul Yildirim, Mehmet Arasli, Muhammet Rasit Sayin, Ziyaettin Aktop

“…Tumor necrosis factor-alpha (TNF-𝛼) and interleukin-6 (IL-6) are among the sensitive markers of systemic inflammation. The aim of this study was to evaluate the plasma levels of the cytokines; TNF-𝛼 and IL-6 in CAE patients. …”
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Neuron-Specific Fluorescence Reporter-Based Live Cell Tracing for Transdifferentiation of Mesenchymal Stem Cells into Neurons by Chemical Compound by Do Won Hwang, Hyun Woo Kwon, Jaeho Jang, Hee Jung Jung, Kwang Rok Kim, Dong Soo Lee

“…Two days after NHPDQC treatment, MSCs showed neuron-like phenotype with neurite outgrowth and high expression of neuron-specific markers in more than 95% cells. The fluorescence signals increased in the cytoplasm of pTα1-DsRed2-transfected MSCs after NHPDQC treatment. …”
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Potential value of novel multiparametric MRI radiomics for preoperative prediction of microsatellite instability and Ki-67 expression in endometrial cancer by Zhichao Wang, Yan Hu, Jun Cai, Jinyuan Xie, Chao Li, Xiandong Wu, Jingjing Li, Haifeng Luo, Chuchu He

“…The hybrid radiomics model (HMRadSum) was developed by extracting quantitative imaging features and deep learning features from multiparametric MRI using emerging attention mechanism. Tumor markers were subsequently predicted utilizing an XGBoost classifier. …”
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Rheopheresis in treatment of idiopathic sensorineural sudden hearing loss by Milan Kostal, Jakub Drsata, Milan Bláha, Miriam Lánská, Viktor Chrobok

“…Older age (p = 0.003), presence of vertigo (p = 0.006) and more profound initial hearing loss (p < 0.001) were identified as negative prognostic markers. Conclusion Rheopheresis can be used as a potentially effective and safe salvage therapy for patients with cortico-refractory SISHL.…”
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Rapamycin Improves Palmitate-Induced ER Stress/NF κ B Pathways Associated with Stimulating Autophagy in Adipocytes by Jiajing Yin, Liping Gu, Yufan Wang, Nengguang Fan, Yuhang Ma, Yongde Peng

“…Inhibiting autophagy with chloroquine (CQ) exacerbated these ER stress markers, indicating the role of autophagy in ameliorating ER stress. …”
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