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5181
Interplay between oxidative stress, neuroinflammatory cytokines and melatonin in Alzheimer's disease: Insights from cerebrospinal fluid analysis
Published 2025-01-01“…CSF levels of Aβ, T-tau and P-tau were assayed, and patients were further classified according to threshold CSF levels of the three markers protein following the criteria of NIA-AA. …”
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5182
Prolonged impacts of sodium glucose cotransporter-2 inhibitors on metabolic dysfunction-associated steatotic liver disease in type 2 diabetes: a retrospective analysis through magn...
Published 2024-08-01“…The beneficial effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors in people with type 2 diabetes (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD) have been suggested in several reports based on serological markers, imaging data, and histopathology associated with steatotic liver disease. …”
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5183
Sex differences in the murine HPA axis after acute and repeated restraint stress
Published 2025-12-01“…After acute stress, female mice showed increased corticosterone secretion and changes in molecular markers suggesting increased HPA axis feedback sensitivity. …”
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5184
From micro to macro, nanotechnology demystifies acute pancreatitis: a new generation of treatment options emerges
Published 2025-01-01“…In particular, the changes in inflammatory markers and therapeutic outcomes following the administration of nanomaterials are examined. …”
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5185
Effects of ultra-processed foods on the liver: insights from gut microbiome and metabolomics studies in rats
Published 2025-01-01“…Some serum biochemical indices, inflammatory factors, oxidative stress markers, hematoxylin–eosin (HE) staining of the liver, 16S ribosomal RNA (rRNA) and Liquid chromatography-mass spectrometry (LC–MS) of rat feces were detected.ResultsThe UPF diet-induced simple steatosis of the liver in rats without affecting the levels of IL-6, GSH, MDA, and SOD. …”
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5186
Impaired Lymphocyte Profile in Schistosomiasis Patients with Periportal Fibrosis
Published 2013-01-01“…Peripheral blood mononuclear cells were obtained by the Ficcol-hypaque gradient and the frequency of T cells expressing the surface markers CD28, CD69, CD25, and CTLA-4 was determined by flow cytometry. …”
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5187
Immunofluorescence for Detection of TOR Kinase Activity In Situ in Photosynthetic Organisms
Published 2024-12-01“…In addition, different ultrastructural cell markers can also be used, such as for nucleus and cell wall detection, allowing a detailed analysis of cell morphology. …”
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5188
Safety evaluation of ethanol extract from Artocarpus altilis leaves as a herbal medicine candidate: Studies in acute and subchronic toxicity
Published 2025-02-01“…Mortality, variations in body weight, hematological and biochemical markers, organ index, and the histology of vital organs were all used to study toxic symptoms. …”
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5189
Skin Autofluorescence Relates to Soluble Receptor for Advanced Glycation End-Products and Albuminuria in Diabetes Mellitus
Published 2013-01-01“…The aim of this study was to compare skin autofluorescence caused by advanced glycation end-products (AGEs) with biochemical markers of endothelial dysfunction and soluble receptor for AGEs (sRAGE) in patients with diabetes. …”
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5190
Standardization of Tragopogon graminifolius DC. Extract Based on Phenolic Compounds and Antioxidant Activity
Published 2014-01-01“…Generally, phenolic compounds are one of the major constituents of TG and could be used as markers for standardization of dosage forms prepared from this plant. …”
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5191
Continuous Genetic Assessment of the Impact of Hatchery Releases on Larimichthys crocea Stocks in China
Published 2025-04-01“…In this study, we analyzed hatchery-released stocks (HRS), and wild-captured stocks in the semi-closed Sansha Bay (SBS, northern Fujian) and in the open waters of southern Fujian (SFS) over four consecutive years (2020–2023) using microsatellite markers. Our results reveal the significant genetic differentiation and distinct contribution rates between SBS and SFS, highlighting the region-specific impacts of restocking. …”
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5192
Association of Maternal Age to Development and Progression of Retinopathy of Prematurity in Infants of Gestational Age under 33 Weeks
Published 2014-01-01“…To find predictive and indicative markers of risk for development of retinopathy of prematurity (ROP) and its progression to the stage requiring laser treatment, in premature infants whose gestational age (GA) was under 33 weeks. …”
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5193
Therapeutic Effect and Location of GFP-Labeled Placental Mesenchymal Stem Cells on Hepatic Fibrosis in Rats
Published 2017-01-01“…The expression levels of fibrotic markers, transforming growth factor β1 (TGF-β1) and α-smooth muscle actin (α-SMA), were assessed using real-time polymerase chain reaction. …”
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5194
The Expression Level of mRNA, Protein, and DNA Methylation Status of FOSL2 of Uyghur in XinJiang in Type 2 Diabetes
Published 2016-01-01“…Methylation of CpG sites was found to inversely correlate with expression of other markers. Conclusions. Results show that a correlation between mRNA, protein, and DNA methylation of FOSL2 gene exists among T2DM patients from Uyghur. …”
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5195
The impact of genetic polymorphisms of IL28B gene on the efficacy of antiviral therapy of the chronic hepatitis C by using the standard Interferon-<i>α</i>
Published 2013-03-01“…The analysis of the efficacy of the treatment was conducted on the basis of the assessment of the normalization of the biochemical cytolysis markers during and after the treatment as well as the availability of the rapid, early and stable virology response.Results. …”
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5196
Diagnostic and prognostic values of tsRNAs in lung cancer: a meta-analysis
Published 2025-01-01“…Diagnostic odds ratios (DORs) and areas under the receiver operating characteristic curve (AUCs) were used to evaluate the potential of tsRNAs as diagnostic markers for LC. Furthermore, hazard ratios (HRs) and 95% confidence intervals (95% CIs) were used to analyze association of tsRNAs with LC prognosis. …”
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5197
Proteomic profiling identifies upregulation of aurora kinases causing resistance to taxane-type chemotherapy in triple negative breast cancer
Published 2025-01-01“…In summary, we revealed that Aurora Kinases upregulation after treatment with chemotherapy could confer chemotherapy resistance to TNBC cells, and AURKB could serve as preselection markers for stratifying patients’ response to neoadjuvant chemotherapy.…”
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5198
18F-Fluorothymidine-Pet Imaging of Glioblastoma Multiforme: Effects of Radiation Therapy on Radiotracer Uptake and Molecular Biomarker Patterns
Published 2013-01-01“…Patterns of tumor PET imaging were then compared to immunohistochemistry and immunofluorescence for markers of proliferation (Ki-67), DNA damage and repair (γH2AX), hypoxia (HIF-1α), and angiogenesis (VEGF). …”
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5199
Overall Survival of Elderly Patients Having Surgery for Colorectal Cancer Is Comparable to Younger Patients: Results from a South Asian Population
Published 2017-01-01“…Demographics, tumour characteristics, and serological markers were considered as independent factors. Multivariable analysis was done using the Cox proportional hazard model. …”
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5200
Atlantic mackerel population structure does not support genetically distinct spawning components [version 2; peer review: 1 approved, 2 approved with reservations]
Published 2025-01-01“…Methods Here, the genome of S. scombrus was sequenced and annotated, as an increasing number of population genetic studies have proven the relevance of reference genomes to investigate genomic markers/regions potentially linked to differences at finer scale. …”
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