On the pursuit of reproducibility: the importance of large sample sizes in psychoimmunology by Manivel Rengasamy, Daniel Moriarity, Rebecca Price

“…Abstract Peripheral inflammatory markers (PIMs), such as C-reactive protein (CRP) or white blood cell count (WBC), have been associated with depression severity in meta-analyses and large cohort studies. …”
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Rapid Characterization and Action Mechanism of the Antidiabetic Effect of Diospyros lotus L Using UHPLC-Q-Exactive Orbitrap MS and Network Pharmacology by Shihan Qin, Mingjuan Liu, Sunv Tang, E. Shuai, Ziming Wang, Kaiquan Yu, Wei Cai

“…Second, a network pharmacology study, including target gene prediction and functional enrichment, was applied to screen the main quality markers of Diospyros lotus L and explore its potential mechanism for the treatment of diabetes. …”
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Occurrence, Risk Factors, and Outcomes of Pulmonary Barotrauma in Critically Ill COVID-19 Patients: A Retrospective Cohort Study by Hasan M. Al-Dorzi, Haifa Almujaydia, Reema Nazer, Yara Alhusaini, Aminah Alhamdan, Ajyad Al Jawad

“…Chronic comorbidities and inflammatory markers were similar in both patient groups. Barotrauma occurred in 4/132 patients (3.0%) who received noninvasive ventilation without intubation, and in 43/280 patients (15.4%) who received invasive mechanical ventilation. …”
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Modulation of Inflammatory Reactions by Low-Dose Ionizing Radiation: Cytokine Release of Murine Endothelial Cells Is Dependent on Culture Conditions by Sabine Schröder, Stephan Kriesen, Daniel Paape, Guido Hildebrandt, Katrin Manda

“…After LD-RT, a screening of numerous inflammatory markers was determined by multiplex assay, followed by detailed analyses of four cytokines (KC, MCP-1, RANTES, and G-CSF). …”
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Evaluation of Platelet Parameters in Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma in a Background of Oral Submucous Fibrosis by Packiaraj Selvajothi Ranjitham, Subramanian Kuzhali, Muthu Ponnuswamy Sumathy, Santiago Gnandeepam

“…Context: The role of platelet parameters as markers of inflammation in various diseases is now in limelight. …”
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Tackling somatic DNA contamination in sperm epigenetic studies by Anamika Kumari, Anamika Kumari, Rajender Singh, Rajender Singh

“…Apart from incorporating simple quality checks, such as microscopic examination and somatic cell lysis buffer (SCLB) treatment, we compared the Infinium Human Methylation 450K BeadChip data for sperm and blood samples to identify the CpG sites that were highly methylated in blood samples in comparison to sperm, but were unrelated to infertility.Results and discussionThe comparison of Infinium Human Methylation 450K BeadChip data for sperm and blood samples identified 9564 CpG sites that can be used as markers for analyzing somatic DNA contamination. We have put together a comprehensive plan including evaluation under a microscope, SCLB treatment, inclusion of CpG biomarkers for sample quality evaluation, and applying a 15% cut off at the time of data analysis to completely eliminate the influence of somatic DNA contamination in sperm epigenetic studies. …”
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The Potential Diagnostic Value of Immune-Related Genes in Interstitial Fibrosis and Tubular Atrophy after Kidney Transplantation by Bin Yang, Dike Shi, Yahong Chen, Yi Zhu

“…The aim of this study was to reveal new diagnostic markers of IF/TA based on bioinformatics analysis. …”
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Diagnostic value of cerebrospinal fluid levels of D-lactate, tumour necrosis factor-alpha and interleukin-6, -8, and -17 in suspected nosocomial meningitis by Sibel Yorulmaz Goktas, Arzu Yılmaztepe Oral, Emel Yılmaz, Emin Halis Akalın, Furkan Guvenc, Guven Ozkaya, Hasan Kocaeli, Seref Dogan, Selcuk Yılmazlar, Haluk Barbaros Oral

“…Conclusion: Our study findings suggest that IL-6, IL-8 and D-lactate levels could be diagnostic markers for nosocomial meningitis.…”
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Pyroptosis-Related Signature Predicts the Progression of Ulcerative Colitis and Colitis-Associated Colorectal Cancer as well as the Anti-TNF Therapeutic Response by Yumei Ning, Kun Lin, Jun Fang, Xiaojia Chen, Xinyi Hu, Lan Liu, Qiu Zhao, Haizhou Wang, Fan Wang

“…These findings can improve our understanding of PRGs in UC and provide new markers for predicting the occurrence of active UC or CAC and the treatment of UC.…”
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Tissue-specific resistance and susceptibility to the tomato brown rugose fruit virus (ToBRFV) conferred by Solanum pennellii loci by Edan Rochsar, Shai Torgeman, Kfir Bandel, Amnon Koren, Chen Klap, Aviv Dombrovsky, Dani Zamir

“…Results The BILs were inoculated and genotyped for 5000 single primer enrichment technology (SPET) markers and phenotyped for virus presence, using ELISA, and for visual symptoms in the terminal shoot, axillary shoots, and fruits. …”
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Semaphorin3B Promotes Proliferation and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in a High-Glucose Microenvironment by Quan Xing, Jingyi Feng, Xiaolei Zhang

“…Furthermore, HG inhibited osteogenic differentiation in BMSCs by decreasing the expression of bone formation markers, alkaline phosphatase (ALP) activity, and mineralization. …”
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Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx protein. by Qian Qiu, Zihan He, Jing Liu, Huijun Xu, Jinyu Wang, Nannan Liu, Ning Kang, Shaokun Pan, Weien Yu, Zixiang Gao, Shimei Zhang, Yang Yang, Qiang Deng, Youhua Xie, Jiming Zhang, Zhongliang Shen

“…In chronic hepatitis B (CHB) patients, immune active phase (IA) is associated with higher intrahepatic expression of MSX1, DNAJA4 and CRYAB, and lower serum HBV markers compared to immune tolerant (IT) phase. Finally, HBV infection is significantly suppressed by MSX1 overexpression in both NTCP-overexpressing cell and humanized liver mouse models. …”
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Evaluation of Fetuses Diagnosed with Megacystis During Prenatal Period by Kemal Sarsmaz, Busra Kanyildiz, Gokcen Orgul, Gokhan Karakoc, Hasan Eroglu, Dilek Sahin, Aykan Yucel

“…The data were analyzed in terms of diagnostic methods, fetal interventions (vesicosynthesis (VS), vesicoamniotic shunt (VAS)), potential prognostic markers and short/long-term prognostic results. Results: A total of 15 megacystis patients were detected. …”
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Tolerability of Capsaicinoids from Capsicum Extract in a Beadlet Form: A Pilot Study by Jayant Deshpande, Shankaranarayanan Jeyakodi, Vijaya Juturu

“…Tolerability assessments and safety blood markers showed no significant changes from baseline. …”
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Pan-cancer analysis and single-cell analysis identifies the CENPN as a biomarker for survival prognosis and immunotherapy by Nie Zhang, Zhuoying He, Xuejin Qin, Ke Han, Zhengchun Zhu, Fei Zhong

“…It is also correlated with genetic markers of immunomodulators in various cancers. Conclusions Overall, CENPN expression is closely related to cancers and has the potential to act as a cancer biomarker.…”
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Changes in Serum Iron, Total Iron Binding Capacity and Transferrin Saturation Percent in Sudanese Females Newly Diagnosed with Breast Cancer at Khartoum Oncology Hospital: A case-... by Rufaida Mustafa Ahmed Mustafa, Nazik Elmalaika Obaid Seid Ahmed Husain

“…Serum iron and transferrin saturation percent may be helpful as biochemical risk markers for breast cancer and TIBC may act as a predictor of disease grade.…”
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A rare neurosurgical emergency: case report of spontaneous lumbar subdural empyema by Svetozar Stanković, Milan Lepić, Ivan Bogićević, Jadranka Stanković, Goran Pavlicević

“…Laboratory tests showed elevated inflammatory markers. Contrast-enhanced magnetic resonance imaging (MRI) revealed lumbar SDE at the L3-L5 levels. …”
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Epithelial-Mesenchymal Transition Phenotype, Metformin, and Survival for Colorectal Cancer Patients with Diabetes Mellitus II by Yaodu Wang, Zhiyang Wu, Likuan Hu

“…We aimed to explore the association between metformin treatment and epithelial-mesenchymal transition (EMT) phenotype and further appraise the prognostic values of metformin and EMT markers E-cadherin and vimentin for colorectal cancer (CRC) in clinical practice. …”
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Canine Mammary Tumors as a Potential Model for Human Breast Cancer in Comparative Oncology by Amirhossein Razavirad, Sanaz Rismanchi, Pejman Mortazavi, Ahad Muhammadnejad

“…In total, 64 canine mammary tumors were selected to study the most common markers, which are applicable for human breast cancer treatment, including estrogen and progesterone receptors (ER and PR), human epidermal growth factor (HER2/neu), Ki67, and cyclooxygenase 2 (Cox2). …”
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Randomised trial of coconut oil, olive oil or butter on blood lipids and other cardiovascular risk factors in healthy men and women by Stephen J Sharp, Kay-Tee Khaw, Robert Luben, Nita G Forouhi, Leila Finikarides, Islam Afzal, Marleen Lentjes

“…The effects of different dietary fats on lipid profiles, metabolic markers and health outcomes may vary not just according to the general classification of their main component fatty acids as saturated or unsaturated but possibly according to different profiles in individual fatty acids, processing methods as well as the foods in which they are consumed or dietary patterns. …”
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