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5041
Trace amine-associated receptors (TAARs)2-9 knockout mice exhibit reduced wakefulness and disrupted REM sleep
Published 2025-01-01“…IntroductionThis study aimed to investigate the role of TAAR2-9 in sleep/wake regulation, given TAAR1's known involvement in modulating neurotransmitter release and sleep patterns.MethodsMale TAAR2-9 knockout (KO) and wild-type (WT) mice were compared using baseline sleep/wake patterns, responses to sleep deprivation, effects of TAAR1 agonists, and dopaminergic markers. EEG recordings and tyrosine hydroxylase immunohistochemistry were used for analysis.ResultsKO mice exhibited lower delta and theta power and higher gamma power, with fragmented sleep characterized by 16% more NREM sleep during the dark phase and 23% more REM sleep during the light phase compared to WT mice. …”
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5042
Clonal Populations of Amniotic Cells by Dilution and Direct Plating: Evidence for Hidden Diversity
Published 2012-01-01“…The differentiation potential of amniotic cells proved to be uncoupled from expression of definitive cell surface or cytoplasmic markers for stromal and epithelial cells. Evidence for diversity among stromal and epithelial cells in amniotic fluid bears on interpretations applied to molecular and functional tests of amniotic cell populations.…”
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5043
Generalisation of EEG-Based Pain Biomarker Classification for Predicting Central Neuropathic Pain in Subacute Spinal Cord Injury
Published 2025-01-01“…<b>Background:</b> The objective was to test the generalisability of electroencephalography (EEG) markers of future pain using two independent datasets. …”
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5044
Systemic Factors Related to Intraocular Levels of Interleukin-6 and Vascular Endothelial Growth Factor in Diabetic Retinopathy
Published 2019-01-01“…One day before PPV, patient characteristics were recorded and a number of systemic markers were amassed, including fasting and postprandial glucose, homeostasis model assessment- (HOMA-) IR, HOMA-beta, C-peptide, insulin, total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, apolipoprotein- (Apo-) A, Apo-B, and lipoprotein A (Lp-A). …”
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5045
Differences in Lower Extremity Kinematics Between High School Cross-Country and Young Adult Recreational Runners
Published 2021-02-01“… # Methods Twenty-five high school cross-country runners (13 women, 12 men) and 25 young adult recreational runners (12 women, 13 men) consented to participate in this study. Reflective markers were placed on each lower extremity over multiple anatomical landmarks. …”
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5046
Rice breeding for higher crop productivity (a review)
Published 2024-05-01“…The hybrid is classified as “super rice”.Modern breeding programs are aimed at producing cultivars of “Green Super Rice” using pedigree methods and backcrossing for introgression of target genes through DNA markers, QTL mapping, pyramiding, and recurrent selection.Russian breeders have traditionally produced rice cultivars adapted to local conditions, with a growing season of no more than 125 days. …”
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5047
Assessment of Haematological Parameters in Drug-Resistant TB
Published 2023-03-01“…This means that these haematological markers can be used to assess a patient's diagnosis, prognosis, and treatment outcome. …”
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5048
Translating the Brazilian Dietary Guidelines into clinical practice: innovative strategies for healthcare professionals
Published 2025-02-01“…The Protocols operationalize the assessment of individuals’ dietary patterns using the Food Consumption Markers Questionnaire and support the delivery of personalized and priority recommendations through a stepwise flowchart. …”
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5049
Higher Concentrations of BCAAs and 3-HIB Are Associated with Insulin Resistance in the Transition from Gestational Diabetes to Type 2 Diabetes
Published 2018-01-01“…In addition to well-known clinical risk factors, BCAAs and 3-hydroxyisobyturate are potential markers to be evaluated as predictors of metabolic risk after pregnancy complicated by GDM.…”
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5050
CD4+T and CD8+T Cells in Uterus Exhibit Both Selective Dysfunction and Residency Signatures
Published 2024-01-01“…It showed that most of CD4+T cells and CD8+T cells in murine uterus and human endometrium were tissue resident memory T cells which highly expressed tissue residence markers CD69 and/or CD103. In addition, both CD4+T cells and CD8+T cells in uterus highly expressed inhibitory molecular PD-1 and cytokine IFN-γ. …”
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5051
Single-cell RNA sequencing reveals tumor heterogeneity in small cell neuroendocrine cervical carcinoma
Published 2025-02-01“…Based on immunohistochemical staining of malignant subtyping markers, a cohort of 66 SCNECC patients from our hospital were divided into five subtypes. …”
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5052
The Relationship between a New Biomarker of Vagal Neuroimmunomodulation and Survival in Two Fatal Cancers
Published 2018-01-01“…We retroactively derived markers of vagal nerve activity indexed by heart rate variability (HRV), specifically the root mean square of successive differences (RMSSD), from patients’ electrocardiograms near diagnosis. …”
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5053
Alterations in Mesenteric Lymph Node T Cell Phenotype and Cytokine Secretion are Associated with Changes in Thymocyte Phenotype after LP-BM5 Retrovirus Infection
Published 2005-01-01“…Simultaneous analysis of surface markers and cytokine secretion was done in an attempt to understand whether the deregulation of IFN-Υ secretion could be ascribed to a defined cell phenotype, concluding that all T cell subsets studied increased IFN-Υ secretion after retrovirus infection. …”
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5054
Spherical harmonics texture extraction for versatile analysis of biological objects.
Published 2025-01-01“…Additionally, we use a similar pipeline on 2D cell migration data to extract the polarization direction and quantify the alignment of fluorescent markers to the migration direction. We implemented the Spherical Texture method as a plugin in ilastik to provide a parameter-free and data-agnostic application to any segmented 3D or 2D dataset. …”
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5055
A synchronous occurrence of breast cancer and pleural mesothelioma: a case report
Published 2025-01-01“…A computed tomography scan revealed pleural thickening, and a pleural biopsy confirmed the diagnosis of malignant pleural mesothelioma, with positive results for the diagnostic markers WT1 and D240. Conclusion This case represents a rare occurrence of synchronous breast cancer and pleural mesothelioma in a 40-year-old female, and is the first case reported in Khyber Pakhtunkhwa, Pakistan. …”
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5056
Oct4 Gene Expression in Primary Colorectal Cancer Promotes Liver Metastasis
Published 2019-01-01“…Oct4-EGFP-positive cells highly expressed stem cell-associated markers and had self-renewal and differentiation abilities. …”
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5057
Sacral Space of Ethnic Buryatia: The Cult of Healing Springs
Published 2024-09-01“…Ethnic Buryatia’s sacral map comprises a variety of spatial elements, such as border markers of settlements, places for economic pursuits, burial grounds, and those of hierophanies. …”
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5058
Dietary Antioxidant Capacity Indices are Negatively Correlated to LDL-Oxidation in Adults
Published 2023-01-01“…Results of this study showed that DTAC and PI were inversely associated with ox-LDL as markers of lipid peroxidation. But no correlations were seen between MDA and dietary antioxidant indices.…”
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5059
Stunting as a Risk Factor of Soil-Transmitted Helminthiasis in Children: A Literature Review
Published 2022-01-01“…Increased inflammatory markers and intestinal microbiota dysbiosis might have increased the intensity of STH infection in stunted children that caused impairment in the immune system. …”
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5060
Authoritarianism vs Democracy as a Key Contradiction in Approaching the Study of Political Leadership
Published 2024-12-01“…In most scientific publications, especially by foreign authors, these concepts are interpreted not so much substantively as ideologically, turning into markers of commitment to conservative or liberal narratives. …”
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