Placental Growth Factor, Soluble fms-Like Tyrosine Kinase 1, Soluble Endoglin, IL-6, and IL-16 as Biomarkers in Preeclampsia by Carmen Rădulescu, Anca Bacârea, Adina Huțanu, Rozalia Gabor, Minodora Dobreanu

“…We compared the serum levels of soluble markers analysed in preeclamptic women and controls during the second and third trimesters of pregnancy and we found that the best predictor for PE was PlGF with a sensitivity of 100% at a concentration threshold of 120.16 pg/mL, a diagnosis accuracy of 70.8%, and AUC of 0.684 (p=0.005). …”
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Risk Factors and Symptoms of Meibomian Gland Loss in a Healthy Population by Anna Machalińska, Aleksandra Zakrzewska, Krzysztof Safranow, Barbara Wiszniewska, Bogusław Machaliński

“…The aim of this study was to investigate the relationships between MGL and ocular symptoms, several systemic conditions, and key markers of ocular surface health. Methods. We included into the study 91 healthy volunteers between the ages of 20 and 77 years. …”
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Ziziphus jujube promotes fertility and pregnancy outcomes in Rat model of uterine adhesions by Fereshteh Asgharzadeh, Fereshteh Asgharzadeh, Mahsa Attarian, Majid Khazaei, Majid Khazaei, Abdulridha Mohammed Al-Asady, Abdulridha Mohammed Al-Asady, Abdulridha Mohammed Al-Asady, Saeide Mansoori, Hamideh Naimi, Moein Eskandari, Azar Khorrami, Seyedeh Elnaz Nazari, Akram Aminian, Marjaneh Farazastanian, Elaheh Eshtad, Amir Avan, Amir Avan, Mikhail Ryzhikov, Malihe Hasanzadeh, Seyed Mahdi Hassanian, Seyed Mahdi Hassanian

“…Fibrotic changes were examined through histological Trichrome staining and analysis of pro-fibrotic factors.ResultsTreatment with Z. jujube resulted in a significant reduction in uterine tissue fibrosis, as evidenced by histological evaluation and reduced expression of fibrotic markers. The intervention demonstrated positive outcomes in embryonic development, pregnancy rates, and pregnancy outcomes. …”
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Relationships between Cognitive Function and Odor Identification, Balance Capability, and Muscle Strength in Middle-Aged Persons with and without Type 2 Diabetes by Manabu Midorikawa, Hiroaki Suzuki, Yasuhiro Suzuki, Kazuyoshi Yamauchi, Hiroyuki Sato, Kiyotaka Nemoto, Yoko Sugano, Hitoshi Iwasaki, Motohiro Sekiya, Shigeru Yatoh, Naoya Yahagi, Yasushi Hada, Tetsuaki Arai, Hitoshi Shimano

“…Odor identification, balance capability, and knee extension strength were potential markers for cognitive decline in middle-aged persons with T2D.…”
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Neutropenic Sepsis in the ICU: Outcome Predictors in a Two-Phase Model and Microbiology Findings by Jan M. Kruse, Thomas Jenning, Sibylle Rademacher, Renate Arnold, Clemens A. Schmitt, Achim Jörres, Philipp Enghard, Michael Oppert

“…All 12.352 patients admitted between 2006 and 2011 to the medical ICUs of our tertiary university center were screened for neutropenia; out of 558 patients identified, 102 fulfilled the inclusion criteria and were analyzed. Severity markers and outcome predictors were assessed. Results. …”
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Mn-doped ZnO thin films as a platform for reagentless uric acid biosensor by Bilasini Devi Naorem, Jatinder Pal Singh, Babita Sharma, Satyam Garg, Athira C, Hashima Sherin, Mahima Momaliya, Muskan, Shubhi Sahu, Arijit Chowdhuri, Mallika Verma, Monika Tomar, Neha Batra

“…The fabricated biosensor exhibits excellent performance in terms of sensitivity (40 µAmM-1cm-2), selectivity with <5 % deviation found in presence of other known markers present in human sera, and shelf life >12 weeks, enabling precise and sensitive uric acid detection. …”
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The Reproducibility of Indoor Air Pollution (IAP) Measurement: A Test Case for the Measurement of Key Air Pollutants from the Pan Frying of Fish Samples by Ki-Hyun Kim, Yong-Hyun Kim, Bo-Won Kim, Jeong-Hyeon Ahn, Min-Suk Bae, Richard J. C. Brown

“…A total of 11 experiments were carried out to measure a list of key variables commonly used to represent indoor air pollution (IAP) indicators such as particulate matter (PM: PM1, PM2.5, PM10, and TSP) and a set of individual volatile organic compounds (VOCs) with some odor markers. The cooking activity conducted as part of our experiments was successful to consistently generate significant pollution levels (mean PM10: 7110 μg m−3 and mean total VOC (TVOC): 1400 μg m−3, resp.). …”
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An Immunocompetent HIV-Negative Elderly Patient with Low-Grade Fever, Generalized Lymphadenopathy, Splenomegaly, and Acute Phase Response: Do Not Forget Castleman Disease by Kalliopi Azariadis, Maria Ioannou, Kalliopi Zachou, George N. Dalekos

“…Laboratory findings showed anemia and increased markers of inflammation including hyperferritinemia and polyclonal hyperglobulinemia. …”
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Mechanical Ventilation and the Titer of Antibodies as Risk Factors for the Development of Transfusion-Related Lung Injury by A. P. J. Vlaar, M. T. Kuipers, J. J. Hofstra, E. K. Wolthuis, C. W. Wieland, J. J. T. H. Roelofs, L. Boon, M. J. Schultz, R. Lutter, N. P. Juffermans

“…MV with high tidal volumes resulted in increased levels of all markers of lung injury compared to animals ventilated with low tidal MV. …”
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Profiling the Secretome of Glioblastoma Cells Under Histone Deacetylase Inhibition Using Mass Spectrometry by Aline Menezes, Yara Martins, Fábio Nogueira, Denise De Abreu Pereira, Katia Carneiro

“…In contrast, key angiogenesis markers such as VEGF and ECM proteins like fibronectin and integrins did not display significant changes. …”
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The gut microbiota predicts and time-restricted feeding delays experimental colitis by Hannah K. Ruple, Eva Haasis, Anna Bettenburg, Carina Maier, Carolin Fritz, Laura Schüle, Sarah Löcker, Yvonne Soltow, Lynn Schintgen, Nina S. Schmidt, Celine Schneider, Axel Lorentz, W. Florian Fricke

“…TRF delayed colitis onset reduced the expression of inflammatory markers and increased the expression of clock genes in the intestine, and increased gut microbiota rhythmicity in IL-10-/- mice. …”
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The Secretome of Bone Marrow and Wharton Jelly Derived Mesenchymal Stem Cells Induces Differentiation and Neurite Outgrowth in SH-SY5Y Cells by Ana O. Pires, Andreia Neves-Carvalho, Nuno Sousa, António J. Salgado

“…Finally, neurite lengths assessment and quantitative real-time reverse-transcription polymerase chain reaction (RT-PCR) analysis demonstrated that CM from BMSCs and HUCPVCs differently induced neurite outgrowth and mRNA levels of neuronal markers exhibited by SH-SY5Y cells. Overall, our results show that the secretome of both BMSCs and HUCPVCs was capable of supporting SH-SY5Y cells survival and promoting their differentiation towards a neuronal phenotype.…”
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Revealing study and breeding implications for production traits and tail characteristics in Simmental cattle by GWAS by Jie Wang, Na Shen, Kaisen Zhao, Jiayu Liao, Genglong Jiang, Jianghai Xiao, Xianbo Jia, Wenqiang Sun, Songjia Lai

“…Interestingly, candidate genes IL1RAP, AQP9, ITPR2, and PKD2 were also associated with metabolic inflammation in cattle tails. These genetic markers offer valuable insights into the traits of Simmental cattle, facilitating the development of molecular breeding strategies to enhance production value and provide references for breeding programs.…”
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Blood-based biomarkers in mild behavioral impairment: an updated overview by Efthalia Angelopoulou, Xenia Androni, Chiara Villa, Alexandros Hatzimanolis, Nikolaos Scarmeas, Sokratis Papageorgiou

“…In this context, MBI has been associated with lower plasma Aβ42/Αβ40 ratio, higher plasma phosphorylated tau at threonine 181 (p-tau181), increased neurofilament light chain (NfL) levels, as well as disturbances in metabolic markers, including homocysteine, insulin and ferritin, suggesting a multifaceted neurobiological basis for this syndrome. …”
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Protein Kinase Cα Modulates Estrogen-Receptor-Dependent Transcription and Proliferation in Endometrial Cancer Cells by Alicia M. Thorne, Twila A. Jackson, Van C. Willis, Andrew P. Bradford

“…PKCα-dependent pathways may provide much needed prognostic markers of aggressive disease and novel therapeutic targets in ER positive tumors.…”
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2,4-Thiazolidinedione Treatment Improves the Innate Immune Response in Dairy Goats with Induced Subclinical Mastitis by Fernanda Rosa, Johan S. Osorio, Erminio Trevisi, Francisco Yanqui-Rivera, Charles T. Estill, Massimo Bionaz

“…TZD treatment did not affect milk fat but had positive effect on milk somatic cells count, blood nonesterified fatty acids, inflammatory markers, and liver function. TZD significantly increased myeloperoxidase but did not affect leukocytes phagocytosis or insulin. …”
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Migration, Proliferation, and Differentiation of Cord Blood Mesenchymal Stromal Cells Treated with Histone Deacetylase Inhibitor Valproic Acid by Leah A. Marquez-Curtis, Yuanyuan Qiu, April Xu, Anna Janowska-Wieczorek

“…We found that in MSC, VPA increased (i) the gene and total protein expression of CXCR4 and CXCR7 and primed migration towards a low gradient of SDF-1, (ii) the gene expression of MMP-2 and secretion and activation of proMMP-2, (iii) the proliferation and gene expression of pluripotency markers SOX2 and Oct-4, and exposure to lower concentrations of VPA (≤5 mM) had no effect on their differentiation to osteocytes and chondrocytes. …”
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Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use by J. M. J. Van den Bergh, E. L. J. M. Smits, M. Versteven, H. De Reu, Z. N. Berneman, V. F. I. Van Tendeloo, E. Lion

“…In this study, we demonstrate that upon electroporation with both IL-15 and IL-15Rα-encoding messenger RNA, mature DC become highly positive for surface IL-15, without influencing the expression of prototypic mature DC markers and with preservation of their cytokine-producing capacity and their migratory profile. …”
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L-theanine modulates tissue cortisol levels in zebrafish after single stress by Vinícius Luís da Silva, Mariana Spanamberg Mayer, Andriele dos Reis Severo, Andressa Leal Zambra, Joanna Moraes De Almeida, Laura Moura Sestari, Mariana Migliorini Parisi, Ana Cristina Vendrametto Varrone Giacomini, Murilo Sander De Abreu, Josiane Woutheres Bortolotto, Gabriela Bonfanti-Azzolin

“…Thus, this study investigates the effect of L-theanine on the response to acute stress, evaluated by tissue cortisol level, oxidative status markers, and behavioral parameters, in zebrafish. …”
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A Natural Flavonoid Glucoside, Icariin, Regulates Th17 and Alleviates Rheumatoid Arthritis in a Murine Model by Liqun Chi, Wenyuan Gao, Xiangrong Shu, Xin Lu

“…Icariin inhibits the expression of various osteoclastogenic markers, such as β3 integrin, cathepsin K, and MMP9 in vitro. …”
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