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4981
Modulation of Biomaterial‐Associated Fibrosis by Means of Combined Physicochemical Material Properties
Published 2025-01-01“…Normal human dermal fibroblasts (NHDFs) are screened for cell density, area, and myofibroblast markers α‐smooth muscle actin (α‐SMA) and Collagen type I (COL1) after 24 h and 7 days of culture, with or without transforming growth factor‐beta (TGF‐β). …”
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4982
Parchment Glutamine Index (PQI): A novel method to estimate glutamine deamidation levels in parchment collagen obtained from low-quality MALDI-TOF data
Published 2023-01-01“…After pre-processing raw spectra, we used weighted least-squares linear regression to estimate Q deamidation levels from the convoluted isotopic envelope for seven collagen-peptide markers. Finally, we employed a linear mixed effect model to predict the overall deamidation level of a parchment sample termed Parchment Glutamine Index (PQI). …”
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4983
MXene−Graphene Oxide Heterostructured Films for Enhanced Metasurface Plasmonic Biosensing in Continuous Glucose Monitoring
Published 2025-01-01“…Abstract Non‐invasive biosensors have attracted attention for their potential to obtain continuous, real‐time physiological information through measurements of biochemical markers, such as one of the most important—glucose, in biological fluids. …”
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4984
Traumatic Brain Injury Promotes Neurogenesis and Oligodendrogenesis in Subcortical Brain Regions of Mice
Published 2025-01-01“…To assess cellular proliferation and differentiation, we administered 5-ethinyl-2′-deoxyuridine (EdU) and determined the number and identity of dividing cells 2 h later using markers of neuronal precursors and astro-, micro-, and oligodendroglia. …”
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4985
Kidney Injury Molecule 1 (KIM-1) as an Early Predictor for Acute Kidney Injury in Post-Cardiopulmonary Bypass (CPB) in Open Heart Surgery Patients
Published 2019-01-01“…Although serum creatinine is still the gold standard for diagnosis of acute kidney injury searching for other new markers is mandatory. Urinary kidney injury molecule 1 can be used as simple noninvasive and specific biomarker for early diagnosis of acute kidney injury.…”
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4986
IgG4-Related Disease without Overexpression of IgG4: Pathogenesis Implications
Published 2012-01-01“…This case indicated that, to clarify the pathogenesis of IgG4-related disease, current cases should repeat specimen evaluations over the course of IgG4-related disease to define diagnostic markers.…”
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4987
The Blockade of IL6 Counterparts the Osmolar Stress-Induced Apoptosis in Human Conjunctival Epithelial Cells
Published 2016-01-01“…Western blot was conducted to measure the abundance of apoptotic markers and IL6 related downstream signaling pathway. …”
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4988
Real-world clinical multi-omics analyses reveal bifurcation of ER-independent and ER-dependent drug resistance to CDK4/6 inhibitors
Published 2025-01-01“…The ER independent subgroup, growing from 5% pre-treatment to 21% post-progression, is characterized by down-regulated estrogen signaling and enrichment of resistance markers including TP53 mutations, CCNE1 over-expression and Her2/Basal subtypes. …”
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4989
Potential Extensions of the US FRAX Algorithm
Published 2012-01-01“…At baseline, femoral neck (FN) bone density was assessed, as were the clinical risk factors included in FRAX, along with additional fracture risk factors such as bone turnover markers and fall history. Fracture ascertainment through periodic interviews and comprehensive medical record review was performed over 10 years of followup. …”
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4990
Exploring aneuploidies in two-center isolated bovine embryonic stem cell lines: Implications for cultured meat production
Published 2025-06-01“…These cells maintained core pluripotency markers (POU5F1, SOX2, SALL4, NANOG) and demonstrated the ability to differentiate into the three germ layers, indicating their potential for sustainable food applications. …”
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4991
Jingui Shenqi Wan alleviates bone loss induced by primary osteoporosis by inhibiting osteoblast pyroptosis
Published 2025-02-01“…Immunohistochemistry (IHC) was then utilized to evaluate the expression of osteogenic markers, including Osterix (OSX), Runx2, and Osteopontin (OPN). …”
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4992
Effect of Glycyrrhiza glabra L. on Broiler Growth Performance, Slaughter and Carcass Characteristics, Blood biochemistry, and Hematological Parameters: A Systematic Review
Published 2025-01-01“…Licorice supplementation affected blood biochemistry, showing varied impacts on markers like glucose, cho-lesterol, and triglycerides. …”
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4993
A Systematic Review of the Epidemiology, Immunopathogenesis, Diagnosis, and Treatment of Pleural TB in HIV- Infected Patients
Published 2012-01-01“…Adenosine deaminase and interferon gamma are good markers of pleural TB disease even in HIV-infected patients. …”
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4994
The morphofunctional and biochemical characteristics of opisthorchiasis-associated cholangiocarcinoma in a Syrian hamster model
Published 2015-12-01“…Thus, this model can be used to test anticancer drugs, to study the mechanisms of cholangiocarcinogenesis and to search for molecular markers for early diagnosis of bile duct cancer.…”
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4995
Labeling tumor-associated extracellular vesicles with antibody-DNA conjugates for quantitative analysis
Published 2025-01-01“…Antibody-DNA conjugates were used to recognize the epithelial cell adhesion molecule (EpCAM) antigen on the TAE surface and quantify the antigen using qPCR for cancer analysis.DiscussionThis method proposed a new quantitative detection approach for TAEs, which aim to identify specific EV-associated markers for diagnostic or therapeutic, this method could inspire a new idea for tumor diagnosis and detection of other diseases.…”
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4996
Clinicopathologic Significance of HIF-1α, CXCR4, and VEGF Expression in Colon Cancer
Published 2010-01-01“…Therefore, the disease-free survival of all patients after curative resection can be considered in association with all three markers expression.…”
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4997
The Effect of Cyclooxygenase Inhibition on Tendon-Bone Healing in an In Vitro Coculture Model
Published 2015-01-01“…Nonselective COX inhibition and the specific inhibition of COX-2 led to region-specific reductions in markers of calcification and cell viability. We suggest further in vitro and in vivo studies examining the biologic and biomechanical effects of selective and nonselective COX inhibition.…”
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4998
Human Adipose-Derived Mesenchymal Stem Cells Cryopreservation and Thawing Decrease α4-Integrin Expression
Published 2016-01-01“…The immunophenotypic markers expression was largely preserved, and their multipotency was maintained. …”
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4999
A variant W chromosome in Centromochlus heckelii (Siluriformes, Auchenipteridae) and the role of repeated DNA in its heteromorphism
Published 2025-01-01“…The 5S rDNA sites were found in two chromosome pairs, distinguishing this population from other Centromochlinae species and further supporting it as one of the most efficient cytotaxonomic markers within the subfamily.…”
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5000
Fecal microbiota transplantation alleviates radiation enteritis by modulating gut microbiota and metabolite profiles
Published 2025-02-01“…The results demonstrated that FMT, particularly in the M-FMT group, effectively alleviated RE by reducing DAI scores, histological damage, and inflammatory markers while enhancing enzyme activity, superoxide dismutase (SOD) levels, and intestinal absorption. …”
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