Reversal of acetaminophen-generated oxidative stress and concomitant hepatotoxicity by a phytopharmaceutical product by Afolabi C. Akinmoladun, Kehinde O. Oguntunde, Lawrence O. Owolabi, Omotayo B. Ilesanmi, Joan O. Ogundele, M.Tolulope Olaleye, Afolabi A. Akindahunsi

“…Administration of Trévo™ remarkably ameliorated acetaminophen-induced histopathological alterations and changes in serum and tissue biochemical markers. The protective effect of Trévo™ (4.5 mL/kg) was at par with that of Silymarin (25 mg/kg). …”
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Molecular Features and Methylation Status in Early Onset (≤40 Years) Colorectal Cancer: A Population Based, Case-Control Study by Giulia Magnani, Daniela Furlan, Nora Sahnane, Luca Reggiani Bonetti, Federica Domati, Monica Pedroni

“…Hypermethylation of ESR1, GATA5, and WT1 genes suggests possible markers in the earlier diagnosis of colorectal tumorigenesis.…”
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A Preferable Approach for the Quality Control of Xiaoer Chiqiao Qingre Granules Based on the Combination of Chromatographic Fingerprints and Chemometrics by Tong Xu, Xiaoqi Li, Mengmeng Huang, Qi Wang, Chao Li, Gang Tian, Yan Chen

“…Six main active ingredients (geniposide, paeoniflorin, forsythin, forsythoside A, baicalin, and wogonoside) were selected as chemical markers for simultaneous quantitative analysis, while the results indicated that the content of other five ingredients except forsythoside A presented comparatively stable. …”
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Restoration of a Critical Mandibular Bone Defect Using Human Alveolar Bone-Derived Stem Cells and Porous Nano-HA/Collagen/PLA Scaffold by Xing Wang, Helin Xing, Guilan Zhang, Xia Wu, Xuan Zou, Lin Feng, Dongsheng Wang, Meng Li, Jing Zhao, Jianwei Du, Yan Lv, Lingling E, Hongchen Liu

“…Real-time PCR and electrochemiluminescence immunoassays demonstrated that osteogenic markers were upregulated by osteogenic preinduction. …”
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Clonal Heterogeneity in the Neuronal and Glial Differentiation of Dental Pulp Stem/Progenitor Cells by Fraser I. Young, Vsevolod Telezhkin, Sarah J. Youde, Martin S. Langley, Maria Stack, Paul J. Kemp, Rachel J. Waddington, Alastair J. Sloan, Bing Song

“…Together, these results demonstrate that appropriate markers may be used to provide an early indication of the suitability of a cell population for purposes where differentiation into a specific lineage may be beneficial and highlight that further understanding of heterogeneity within mixed cellular populations is required.…”
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Evaluation of Tissue Homogenization to Support the Generation of GMP-Compliant Mesenchymal Stromal Cells from the Umbilical Cord by Ryan J. Emnett, Aparna Kaul, Aleksandar Babic, Vicki Geiler, Donna Regan, Gilad Gross, Salem Akel

“…Interestingly, there was no difference in the expression of mesenchymal markers and trilineage differentiation potential of cells generated using either method. …”
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The Serum S100B Level as a Biomarker of Enteroglial Activation in Patients with Ulcerative Colitis by Asuman Celikbilek, Mehmet Celikbilek, Seda Sabah, Nermin Tanık, Elif Borekci, Serkan Dogan, Yavuz Akin, Suleyman Baldane, Kemal Deniz, Neziha Yilmaz, Omer Ozbakir, Mehmet Yucesoy

“…This study investigated whether enteroglial markers, including S100B protein and glial fibrillary acidic protein (GFAP), can serve as noninvasive indicators of EGC activation and disease activity in UC patients. …”
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HPV Infection in Esophageal Squamous Cell Carcinoma and Its Relationship to the Prognosis of Patients in Northern China by Fangli Cao, Hui Han, Fang Zhang, Baozhong Wang, Wei Ma, Yanwen Wang, Guiming Sun, Miao Shi, Yubo Ren, Yufeng Cheng

“…The 5-year overall survival (OS) and progression-free survival were calculated in relation to these markers and the Cox proportional hazards model was used to determine the hazard ratio (HR) of variables in univariate and multivariate analysis. …”
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Supplementation with Korean Red Ginseng Improves Current Perception Threshold in Korean Type 2 Diabetes Patients: A Randomized, Double-Blind, Placebo-Controlled Trial by Kahui Park, YuSik Kim, Junghye Kim, Shinae Kang, Jong Suk Park, Chul Woo Ahn, Ji Sun Nam

“…Secondary outcomes were altered fasting plasma glucose, HbA1c, and various metabolic and inflammatory markers at week 24. Results. Sixty-one patients completed the study. …”
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Changes in Serum Levels of Bone Morphogenic Protein 4 and Inflammatory Cytokines after Bariatric Surgery in Severely Obese Korean Patients with Type 2 Diabetes by Mee Kyoung Kim, Eun-Hee Jang, Oak-Kee Hong, Hyun-Ji Chun, Soon-Jib Yoo, Ki-Hyun Baek, Wook Kim, Eung Kook Kim, Ki-Ho Song, Hyuk-Sang Kwon

“…Serum levels of BMP-4 and various inflammatory markers, including high-sensitivity C-reactive protein (hsCRP), free fatty acids (FFAs), and plasminogen activator inhibitor- (PAI-) 1, were measured before and 12 months after RYGB. …”
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Inhibition of G9a Histone Methyltransferase Converts Bone Marrow Mesenchymal Stem Cells to Cardiac Competent Progenitors by Jinpu Yang, Keerat Kaur, Li Lin Ong, Carol A. Eisenberg, Leonard M. Eisenberg

“…Inhibition of G9a histone methyltransferase by gene specific knockdown or BIX01294 treatment was sufficient to induce expression of precardiac markers Mesp1 and brachyury in bone marrow cells. …”
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Association between Sleep Disruption and Levels of Lipids in Caucasians with Type 2 Diabetes by Wan Aizad Wan Mahmood, Mohd Shazli Draman Yusoff, Lucy Ann Behan, Andrea Di Perna, Tommy Kyaw Tun, John McDermott, Seamus Sreenan

“…In this Caucasian T2DM population, PQ is associated with adverse cardiovascular risk markers, and long and short sleep disruptions have an independent negative impact on lipids. …”
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Anti-TNF-Mediated Modulation of Prohepcidin Improves Iron Availability in Inflammatory Bowel Disease, in an IL-6-Mediated Fashion by Flaminia Cavallaro, Lorena Duca, Laura Francesca Pisani, Roberta Rigolini, Luisa Spina, Gian Eugenio Tontini, Nadia Munizio, Elena Costa, Maria Domenica Cappellini, Maurizio Vecchi, Luca Pastorelli

“…Prohepcidin, erythropoietin, erythroferrone, C reactive protein, interleukin-6, iron markers, and haemoglobin levels were measured and clinical activity indexes were evaluated. …”
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Genomic and algorithm-based predictive risk assessment models for benzene exposure by Minyun Jiang, Minyun Jiang, Na Cai, Na Cai, Juan Hu, Lei Han, Lei Han, Fanwei Xu, Baoli Zhu, Baoli Zhu, Baoli Zhu, Baoli Zhu, Boshen Wang

“…Validation confirmed substantial changes in NFKB1 and PTX3 following exposure, with PTX3 emerging as paramount, suggesting its utility as a diagnostic biomarker for benzene damage.ConclusionRisk assessment models, informed by oxidative stress markers, successfully discriminated between benzene-injured patients and controls.…”
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Multimodal neural correlates of childhood psychopathology by Jessica Royer, Valeria Kebets, Camille Piguet, Jianzhong Chen, Leon Qi Rong Ooi, Matthias Kirschner, Vanessa Siffredi, Bratislav Misic, BT Thomas Yeo, Boris C Bernhardt

“…Our findings help in better understanding biological mechanisms underpinning dimensions of psychopathology, and could provide brain-based vulnerability markers.…”
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The Chromatin Pattern of Cell Nuclei Is of Prognostic Value for Renal Cell Carcinomas by Christine François, Myriam Remmelink, Michel Petein, Roland van Velthoven, André Danguy, Eric Wespes, Isabelle Salmon, Robert Kiss, Christine Decaestecker

“…The actual prognostic values of this set of cytometric variables was compared (by means of discriminant statistical analysis) to conventional diagnostic and/or prognostic markers including histopathological grades, tumour invasion levels and the presence or absence of metastases. …”
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Follicular Thyroid Carcinoma Metastatic to the Kidney: Report of a Case with Cytohistologic Correlation by Vikas Nath, Mithra Baliga, Jack Lewin, Frederico Souza, Israh Akhtar

“…The differential diagnoses of renal metastasis of FTC include the encapsulated follicular variant of papillary thyroid carcinoma (PTC), which possesses some of the nuclear features seen in conventional PTC but may occasionally be indistinguishable from FTC in cytologic preparations, and renal lesions such as benign thyroidization of the kidney and thyroid-like follicular carcinoma of the kidney, which mimic FTC in histologic appearance but do not stain with thyroid markers.…”
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Mesenchymal Progenitors Derived from Different Locations in Long Bones Display Diverse Characteristics by Weiguang Lu, Bo Gao, Jing Fan, Pengzhen Cheng, Yaqian Hu, Qiang Jie, Zhuojing Luo, Liu Yang

“…The three groups exhibited similar cellular morphologies and expressed the typical surface markers associated with mesenchymal stem cells. Interestingly, after cell proliferation assays and bidirectional differentiation analysis, periosteal mesenchymal progenitors showed a higher proliferative ability and adipogenic differentiation potential. …”
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Cathepsin C Is Involved in Macrophage M1 Polarization via p38/MAPK Pathway in Sudden Cardiac Death by Jialin Dai, Jiangjin Liu, Qiong Zhang, Yang An, Bing Xia, Changwu Wan, Yuanyuan Zhang, Yanni Yu, Jie Wang

“…This study was aimed at identifying molecular markers associated with the pathogenesis of sudden cardiac death (SCD). …”
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Decrease in Circulating Dendritic Cell Precursors in Patients with Peripheral Artery Disease by Daniel Kretzschmar, Ilonka Rohm, Sebastian Schäller, Stefan Betge, Rudin Pistulli, Yevgeniya Atiskova, Hans-R. Figulla, Atilla Yilmaz

“…In patients with PAD, a significant decrease in mDCPs, pDCPs, and tDCPs was observed. In immunostaining, markers indicative for mDCs (CD209: 16 versus 8 cells/0.1 mm2, P=0.02; CD83: 19 versus 5 cells/0.1 mm2, P=0.03) were significantly elevated in femoralis plaques compared to control vessels. …”
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