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  1. 4701

    Anlotinib Inhibits Cisplatin Resistance in Non-Small-Cell Lung Cancer Cells by Inhibiting MCL-1 Expression via MET/STAT3/Akt Pathway by Lile Wang, Lu Xu, Shuhua Han, Xiaoli Zhu

    Published 2024-01-01
    “…Protein expression levels of MET, MCL-1, and STAT3/Akt pathway-related markers were examined using western blot analysis. …”
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    Article
  2. 4702

    Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer’s Disease Mutations by Alejandro Soto-Ospina, Pedronel Araque Marín, Gabriel de Jesús Bedoya, Andrés Villegas Lanau

    Published 2021-01-01
    “…Alzheimer’s disease manifests itself in brain tissue by neuronal death, due to aggregation of β-amyloid, produced by senile plaques, and hyperphosphorylation of the tau protein, which produces neurofibrillary tangles. One of the genetic markers of the disease is the gene that translates the presenilin-2 protein, which has mutations that favor the appearance of the disease and has no reported crystallographic structure. …”
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    Article
  3. 4703

    Efficacy of melatonin treatment in a cystic fibrosis mouse model of airway infection by Kristen R. Schaefer, Sara Rogers, Zachary Faber, Thomas J. Kelley

    Published 2025-01-01
    “…Melatonin-treated mice exhibited improved bacterial clearance, reduced inflammatory markers. Mice treated in drinking water for 1 week had improved bacterial clearance but no improvement in inflammation. …”
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    Article
  4. 4704

    The Metabolomic Characterization of Different Types of Coronary Atherosclerotic Heart Disease in Male by Yuxuan Fan, Xianglan Quan, Shengquan Liu, Le Yue, Jizong Jiang, Zhiqing Fan

    Published 2022-01-01
    “…Compared with the stable coronary artery disease group, 15 specific metabolite markers were found in the acute coronary syndrome group. …”
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    Article
  5. 4705

    The individual strategies of Internet users’ media activity by O. A. Grimov, V. A. Belkina

    Published 2023-02-01
    “…The interaction of the individual and media ecosystem is analyzed with the help of a system of incoming and outcoming activity markers. The incoming activity is understood by the authors as a total of institutional and environmental factors of media activity practices realization, the outcoming one is understood as the characteristic of individual’s personal activity in realizing media practices. …”
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  6. 4706

    Derivation of Pluripotent Cells from Mouse SSCs Seems to Be Age Dependent by Hossein Azizi, Sabine Conrad, Ursula Hinz, Behrouz Asgari, Daniel Nanus, Heike Peterziel, Akbar Hajizadeh Moghaddam, Hossein Baharvand, Thomas Skutella

    Published 2016-01-01
    “…The generated ESC-like cells were similar to ESCs and express pluripotency markers. In vitro they differentiate into all three germ lineages; they form complex teratomas after transplantation in SCID mice and produce chimeric mice.…”
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  7. 4707

    NGF-TrkA Axis Enhances PDGF-C-Mediated Angiogenesis in Osteosarcoma via miR-29b-3p Suppression: A Potential Therapeutic Strategy Using Larotrectinib by Sheng-Mou Hou, Ching-Yuan Cheng, Wei-Li Chen, En-Ming Chang, Chih-Yang Lin

    Published 2025-01-01
    “…Analysis of GEO (GSE16088) data identified five angiogenesis markers significantly upregulated in OS tissues. In vitro experiments demonstrated that NGF enhanced HUVEC tube formation by upregulating platelet-derived growth factor C (PDGF-C) expression and suppressing microRNA-29b-3p (miR-29b-3p). …”
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  8. 4708

    Intermittent Fasting Protects Against the Progression from Acute Kidney Injury to Chronic Kidney Disease by Yoonjoo Jang, Young Suk Kim, Seo Rin Kim, Dong Won Lee, Soo Bong Lee, Il Young Kim

    Published 2025-01-01
    “…IF also reduced levels of TGF-β1, phosphorylated NF-κB p65, inflammatory cytokines, and F4/80-positive macrophages, along with markers of oxidative stress. These findings highlight IF’s ability to mitigate fibrosis and EMT through reductions in inflammation and oxidative stress during AKI-to-CKD progression. …”
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  9. 4709

    White Mold: A Global Threat to Crops and Key Strategies for Its Sustainable Management by Md. Motaher Hossain, Farjana Sultana, Md. Tanbir Rubayet, Sabia Khan, Mahabuba Mostafa, Nusrat Jahan Mishu, Md. Abdullah Al Sabbir, Nabela Akter, Ahmad Kabir, Mohammad Golam Mostofa

    Published 2024-12-01
    “…Each stage of infection triggers a cascade of molecular and physiological events that underpin defense responses against <i>S. sclerotiorum</i>. Molecular markers can help rapid diagnosis of this disease in plants. …”
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  10. 4710
  11. 4711
  12. 4712

    New insights into Notch signaling as a crucial pathway of pancreatic cancer stem cell behavior by chrysin-polylactic acid-based nanocomposite by Eman M. Ragab, Doaa M. El Gamal, Fares F. El-najjar, Hager A. Elkomy, Mahmoud A. Ragab, Mariam A. Elantary, Omar M. Basyouni, Sherif M. Moustafa, Shimaa A. EL-Naggar, Abeer S. Elsherbiny

    Published 2025-02-01
    “…These cells are typically identified by the expression of specific cell surface markers. A population of pancreatic cancer stem cells with aberrantly active developmental signaling pathways has been identified in recent studies of human pancreatic tumors. …”
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    Article
  13. 4713

    Estimation and identification of parameters in a lumpedcerebrovascular model by Scott R. Pope, Laura M. Ellwein, Cheryl L. Zapata, Vera Novak, C. T. Kelley, Mette S. Olufsen

    Published 2008-11-01
    “…Thus, the method discussedin this study provides a new methodology to extract clinical markers thatcannot easily be assessed noninvasively.…”
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  14. 4714

    Exploring the Anti-Osteoporotic Effects of <i>n</i>-Hexane Fraction from <i>Cotoneaster wilsonii</i> Nakai: Activation of Runx2 and Osteoblast Differentiation In Vivo by Soyeon Hong, Hee Ju Lee, Da Seul Jung, Saruul Erdenebileg, Hoseong Hwang, Hak Cheol Kwon, Jaeyoung Kwon, Gyhye Yoo

    Published 2025-01-01
    “…Biochemical assays and histological analyses focused on the signaling activation of osteoblast differentiation and osteogenic markers, such as ALP, collagen, and osterix. The CWH significantly activated TGF-β and Wnt signaling, enhancing osteoblast differentiation and bone matrix formation. …”
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  15. 4715

    Protective Effect of Baccharis trimera Extract on Acute Hepatic Injury in a Model of Inflammation Induced by Acetaminophen by Bruno da Cruz Pádua, Joamyr Victor Rossoni Júnior, Cíntia Lopes de Brito Magalhães, Míriam Martins Chaves, Marcelo Eustáquio Silva, Maria Lucia Pedrosa, Gustavo Henrique Bianco de Souza, Geraldo Célio Brandão, Ivanildes Vasconcelos Rodrigues, Wanderson Geraldo Lima, Daniela Caldeira Costa

    Published 2014-01-01
    “…The present study attempted to investigate the protective effect of B. trimera against APAP-induced hepatic damage in rats. The liver-function markers ALT and AST, biomarkers of oxidative stress, antioxidant parameters, and histopathological changes were examined. …”
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  16. 4716

    Structural brain basis of latent factors of executive functions in childhood by Yongjing Li, Keertana Ganesan, Claire R. Smid, Abigail Thompson, Roser Cañigueral, Jessica Royer, Boris Bernhardt, Nikolaus Steinbeis

    Published 2025-01-01
    “…Here, in a sample of 141 children aged 6–13 years, we administered a battery of 9 executive function tasks, derived latent factors of inhibition, working memory, and shifting and examined their associations with markers of brain structure (whole-brain cortical thickness). …”
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  17. 4717

    Protective Role of Platelets in Myocardial Infarction and Ischemia/Reperfusion Injury by Kornela Hałucha, Alina Rak-Pasikowska, Iwona Bil-Lula

    Published 2021-01-01
    “…Additionally, the use of platelet-derived microparticles as possible markers of MI, with and without comorbidities, and their role in cardioprotection are discussed. …”
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  18. 4718

    Adrenal Hemangioma: A Case of Retroperitoneal Tumor by Genta Iwamoto, Kota Shimokihara, Takashi Kawahara, Daiji Takamoto, Masahiro Yao, Jun-ichi Teranishi, Masako Otani, Hiroji Uemura

    Published 2018-01-01
    “…Magnetic resonance imaging (MRI) and positron-emission tomography (PET)-CT were unable to confirm or deny malignancy, and tumor markers, including CEA and CA19-9, showed slight elevation. …”
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  19. 4719

    Assessment of urine CCL2 as a potential diagnostic biomarker for acute kidney injury and septic acute kidney injury in intensive care unit patients by Yuan Peng, Qin Wang, Fang Jin, Tao Tao, Qihong Qin

    Published 2024-12-01
    “…In this study, we investigated the potential of plasma and urine CCL2 levels as diagnostic markers for AKI and SAKI in 216 ICU patients. Our findings revealed significant differences in plasma (p < 0.01) and urine CCL2 (p < 0.0001) levels between AKI and non-AKI patients in the ICU. …”
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  20. 4720

    Prenatal Detection of Silver–Russell Syndrome: A First Trimester Suspicion and Diagnostic Approach by Slavyana Galeva, Giuliana Diglio, Boris Stoilov, Ekaterina Uchikova, Lucian Pop

    Published 2025-01-01
    “…The first-trimester biochemical markers, including PAPP-A and β-hCG, were within the normal range. …”
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