Synergistic Effects of Dantrolene and Nimodipine on the Phenylephrine-Induced Contraction and ACh-Induced Relaxation in Aortic Rings from Diabetic Rats by Maria J. Crespo, Marie Roman, Jonathan Matias, Myrna Morales, Hector Torres, Jose Quidgley

“…The oxidative stress markers malondialdehyde (MDA) and 4-hydroxyalkenal (4-HAE) were also evaluated in the presence and absence of dantrolene and nimodipine. …”
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Impact of Temporomandibular Joint Pain in Rheumatoid Arthritis by Neveen Ahmed, Hamid Masoud Mustafa, Anca Irinel Catrina, Per Alstergren

“…The systemic inflammatory activity was estimated by the disease activity score 28 (DAS28), blood levels of inflammatory markers and number of painful musculoskeletal regions. …”
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Evaluation of the Selenotranscriptome Expression in Two Hepatocellular Carcinoma Cell Lines by Stefano Guariniello, Giovanni Di Bernardo, Giovanni Colonna, Marcella Cammarota, Giuseppe Castello, Susan Costantini

“…Hence, it needs to identify always new putative markers to improve its diagnosis and prognosis. Since the selenium is able to fight the oxidative damage which is one of the major origins of cell damage as well as cancer, we have recently focused our attention on selenoprotein family and their involvement in HCC. …”
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Metabolomics Approach for Discrimination and Quality Control of Natural and Commercial Fallopia multiflora Products in Vietnam by Nguyen Thi Thoa, Nguyen Hai Dang, Do Hoang Giang, Nguyen Thi Thu Minh, Nguyen Tien Dat

“…Multivariate statistical methods such as hierarchical clustering analysis and principal component analysis were utilized to compare and discriminate six natural and twelve commercial samples. 2,3,4′,5-Tetrahydroxystilbene 2-O-β-D-glucopyranoside (THSG) (1), emodin (4), and the new compound 6-hydroxymusizin 8-O-α-D-apiofuranosyl-(1⟶6)-β-D-glucopyranoside (5) could be considered as important markers for classification of F. multiflora. Furthermore, seven phenolics were quantified that the variation in the contents of selected metabolites revealed the differences in the quality of natural and commercial samples. …”
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HIF1α-Induced Glycolysis Metabolism Is Essential to the Activation of Inflammatory Macrophages by Ting Wang, Huiying Liu, Guan Lian, Song-Yang Zhang, Xian Wang, Changtao Jiang

“…RT-PCR results revealed that HIF1α overexpression macrophage had a hyperinflammatory state characterized by the upregulation of M1 markers. Cellular bioenergetics analysis showed lower cellular oxygen consumption rates in the Lysm HIF1α lsl mice. …”
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Protective Action of Antioxidants on Hepatic Damage Induced by Griseofulvin by M. del C. Martinez, S. G. Afonso, A. M. Buzaleh, A. Batlle

“…The aim was to evaluate the possible protective effect of different antioxidant compounds: trolox (Tx), ascorbic acid (Asc), the combination Tx and Asc, melatonin (Mel), and the polyphenols: ellagic acid, quercetin, chlorogenic acid, caffeic acid, gallic acid, and ferulic acid on liver damage and oxidative stress markers in a mouse model of EPP. Coadministration of Gris with Tx, Asc, and its combination, or Mel mainly affected heme biosynthetic pathway, resulting in a decrease in ALA-S activity which was increased by Gris, while the tested polyphenols exerted a protective effect on oxidative stress, decreasing lipid peroxidation and the activity of some antioxidant enzymes. …”
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The Dysexecutive Syndrome Associated with Ischaemic Vascular Disease and Related Subcortical Neuropathology: A Boston Process Approach by Melissa Lamar, Cate C. Price, Tania Giovannetti, Rod Swenson, David J. Libon

“…This review will outline the subtle markers underlying this prefrontal dysfunction, i.e., the dysexecutive phenotype, associated with ischaemic vascular disease and relate it to fundamental impairments of gating subserved by basal ganglia-thalamic pathways within and across various dementia syndromes.…”
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Effect of Lower Extremity Bypass Surgery on Inflammatory Reaction and Endothelial Dysfunction in Type 2 Diabetic Patients by Pei-Hsuan Tsai, Jun-Jen Liu, Szu-Yuan Chou, Yao-Chung Chang, Sung-Ling Yeh

“…This study investigated the alteration of inflammatory and endothelium dysfunction markers before and after LEBS in DM patients. Twenty one type 2 DM patients with LEBS were included. …”
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Self-Renewal Signalling in Presenescent Tetraploid IMR90 Cells by Anda Huna, Kristine Salmina, Elina Jascenko, Gunars Duburs, Inna Inashkina, Jekaterina Erenpreisa

“…At the presenescence stage, a small (2–7%) proportion of cells overcome the 4n-G1 checkpoint, simultaneously inducing self-renewal (NANOG-positivity), the DNA damage response (DDR; γ-H2AX-positive foci), and senescence (p16inka4a- and p21CIP1-positivity) signalling, some cells reach octoploid DNA content and divide. All of these markers initially appear and partially colocalise in the perinucleolar compartment. …”
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Quantitative Analysis of Six Phenolic Acids in Artemisia capillaris (Yinchen) by HPLC-DAD and Their Transformation Pathways in Decoction Preparation Process by Fang Tian, Qun-Jia Ruan, Ying Zhang, Hui Cao, Zhi-Guo Ma, Gai-Lian Zhou, Meng-Hua Wu

“…In conclusion, this study provides a chemical basis for quality control of Yinchen decoction, and the changes of selected markers in decoction could give us some novel perspectives to study the relationship between substances and drug efficacy.…”
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EEG as a neural measure of hypoxia-related impairment by Stephanie R. Otto, Stephanie R. Otto, Cammi K. Borden, Cammi K. Borden, Daniel G. McHail, Kara J. Blacker

“…Collectively, these studies have accumulated support for a variety of candidate neural markers of hypoxia impairment spanning sensory and cognitive domains. …”
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MtCro: multi-task deep learning framework improves multi-trait genomic prediction of crops by Dian Chao, Hao Wang, Fengqiang Wan, Shen Yan, Wei Fang, Yang Yang

“…Abstract Genomic Selection (GS) predicts traits using genome-wide markers, speeding up genetic progress and enhancing breeding efficiency. …”
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Placental, Matrilineal, and Epigenetic Mechanisms Promoting Environmentally Adaptive Development of the Mammalian Brain by Kevin D. Broad, Eridan Rocha-Ferreira, Mariya Hristova

“…Placentation also hands ultimate control of genomic imprinting and intergenerational epigenetic information transfer to the matriline as epigenetic markers undergo erasure and reprogramming in the developing oocyte. …”
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Comparative mitogenome analysis of two ectomycorrhizal fungi (Paxillus) reveals gene rearrangement, intron dynamics, and phylogeny of basidiomycetes by Qiang Li, Yuanhang Ren, Dabing Xiang, Xiaodong Shi, Jianglin Zhao, Lianxin Peng, Gang Zhao

“…Phylogenetic analysis of the combined mitochondrial gene set gave identical and well-supported tree topologies, indicating that mitochondrial genes were reliable molecular markers for analyzing the phylogenetic relationships of Basidiomycota. …”
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Comparison of Modified Chandler, Roller Pump, and Ball Valve Circulation Models for In Vitro Testing in High Blood Flow Conditions: Application in Thrombogenicity Testing of Differ... by Wim van Oeveren, Ignace F. Tielliu, Jurgen de Hart

“…Binding of fibrin and platelets was higer on PET, inflammatory markers were lowest on Dyneema Purity UHMWPE. We concluded that the Hemobile minimally affects blood and could be adjusted to high blood flows, simulating arterial shear stress. …”
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Neuroprotection and Functional Recovery Associated with Decreased Microglial Activation Following Selective Activation of mGluR2/3 Receptors in a Rodent Model of Parkinson's Diseas... by Hugh Chan, Helen Paur, Anthony C. Vernon, Virginia Zabarsky, Krishna P. Datla, Martin J. Croucher, David T. Dexter

“…Interestingly, these beneficial effects were associated with a decrease in microglial markers in the SNc, which may suggest an antiinflammatory action of this drug.…”
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Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma by Ana Almazán-Moga, Patricia Zarzosa, Isaac Vidal, Carla Molist, Irina Giralt, Natalia Navarro, Aroa Soriano, Miguel F. Segura, Arantza Alfranca, Javier Garcia-Castro, José Sánchez de Toledo, Josep Roma, Soledad Gallego

“…Given the lack of suitable markers to identify this subpopulation in aRMS, we used cancer stem cell-enriched supracellular structures (spheres and holoclones) to study this subpopulation. …”
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Karyotype uniformity in populations of the endemic Hemiancistrus fuliginosus (Loricariidae: Hypostomini) collected in the upper and middle Uruguai River by Jocicléia Thums Konerat, Vanessa Bueno, Ana Luiza de Brito Portela-Castro, Isabel Cristina Martins-Santos, Vladimir Pavan Margarido

“…Chromosomal data were important markers to fill gaps and to contribute to morphological and molecular proposals in allocating H. fuliginosus. …”
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Evaluation of Physical Symptoms in Patients on Peritoneal Dialysis by Ana Elizabeth Figueiredo, Cate Goodlad, Michelle Clemenger, San San Haddoub, Jacqueline McGrory, Kim Pryde, Emma Tonkins, Nora Hisole, Edwina Anne Brown

“…Symptoms remain stable over time and do not appear to relate to dialysis parameter markers.…”
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Protective Role of Black Tea Extract against Nonalcoholic Steatohepatitis-Induced Skeletal Dysfunction by Subhra Karmakar, Sangita Majumdar, Anasuya Maiti, Monalisa Choudhury, Aniruddha Ghosh, Asankur S. Das, Chandan Mitra

“…Several urinary (calcium, phosphate, creatinine, and calcium-to-creatinine ratio) serum (alkaline phosphatase and serum tartrate-resistant acid phosphatase), and molecular markers of bone turnover (receptor activator of NF-κB ligand (RANKL), osteoprotegerin (OPG), and estrogen) were tested. …”
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