Alfa-Fetoprotein-Producing Female Primary Urethral Adenocarcinoma with Neuroendocrine Differentiation by Takao Natsuyama, Yozo Mitsui, Masato Uetani, Shigeyuki Ohta, Masafumi Inoue, Koichiro Akakura

“…Enhanced computed tomography showed an approximately 3.0×5.0-cm mass around the proximal urethra and bladder neck. Of examined tumor markers, serum AFP was elevated (48.3 ng/mL), while others including carcinoembryonic antigen were within a normal range. …”
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Deep cryptic diversity in the Craugastor podiciferus Species Group (Anura: Craugastoridae) of Isthmian Central America revealed by mitochondrial and nuclear data by Erick Arias, Andrew J. Crawford, Andreas Hertz, Gabriela Parra Olea

“…We performed exhaustive sampling throughout the geographic distribution of the group to evaluate the phylogenetic relationships and biogeographic history of all named species based on two mitochondrial markers and nuclear ddRAD loci. We also implemented various species delimitation methods to test for the presence of unconfirmed candidate species within the group. …”
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Role of Endothelial Nitric Oxide Synthase in Diabetic Nephropathy: Lessons from Diabetic eNOS Knockout Mice by Takamune Takahashi, Raymond C. Harris

“…The animal models that recapitulate human DN undoubtedly facilitate our understanding of this disease and promote the development of new diagnostic markers and therapeutic interventions. Based on the clinical evidence showing the association of eNOS dysfunction with advanced DN, we and others have created diabetic mice that lack eNOS expression and shown that eNOS-deficient diabetic mice exhibit advanced nephropathic changes with distinct features of progressive DN, including pronounced albuminuria, nodular glomerulosclerosis, mesangiolysis, and arteriolar hyalinosis. …”
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Optimizing Bone Health in Duchenne Muscular Dystrophy by Jason L. Buckner, Sasigarn A. Bowden, John D. Mahan

“…Diagnostic studies, including biochemical markers of bone turnover and bone mineral density by dual energy X-ray absorptiometry (DXA), as well as spinal imaging using densitometric lateral spinal imaging, and treatment to optimize bone health in patients with DMD are discussed. …”
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Pituranthos chloranthus Oil as an Antioxidant-Based Adjuvant Therapy against Cisplatin-Induced Nephrotoxicity by Aida Lahmar, Zaineb Dhaouefi, Rihab Khlifi, Fairouz Sioud, Leila Chekir- Ghedira

“…PC also restored the alterations in oxidative stress markers and proinflammatory cytokine IFN-γ level. …”
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Inflammatory and Oxidative Stress Responses to High-Carbohydrate and High-Fat Meals in Healthy Humans by S. Gregersen, D. Samocha-Bonet, L. K. Heilbronn, L. V. Campbell

“…We speculate that the observed increases in postprandial IL6, without increases in any other markers of inflammation, may indicate a normal IL6 response to enhance glucose uptake, similar to its role postexercise.…”
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Characterization and discrimination of fermented sweet melon juice by different microbial strains via GC-IMS-based volatile profiling and chemometrics by Zhaoling Wang, Si Mi, Xianghong Wang, Kemin Mao, Yuwei Liu, Jie Gao, Yaxin Sang

“…A total of 15 volatiles with both variable importance in projection value > 1 and P < 0.05 were determined as potential markers for the discrimination of fermented sweet melon juice. …”
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Primary Hepatic Lymphoma: A Challenging Diagnosis by D. Myoteri, D. Dellaportas, E. Arkoumani, A. Marinis, A. Zizi-Sermpetzoglou

“…Initial evaluation revealed mildly elevated liver function tests and normal tumor markers, while imaging with an abdominal CT-scan showed multiple hypodense nodules in both liver lobes. …”
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Molecular and Biochemical Characterization of the Greek Pepper ( Capsicum annuum ) Cultivars ‘Florinis’ and ‘Karatzova’ by Niki Mougiou, Foteini Trikka, Sofia Michailidou, Mariana Pantoura, Anagnostis Argiriou

“…In that aspect, genetic profiles of ‘Florinis’, a ‘Florinis’-type and ‘Karatzova’ peppers, were studied using Inter Simple Sequence Repeats (ISSR) molecular markers and an automated fragment detection system. …”
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Effect of fermented bee pollen on metabolic syndrome in high-fat diet-induced mice by Sha Yan, Kai Wang, Xiaoying Wang, Aiqun Ou, Feiran Wang, Liming Wu, Xiaofeng Xue

“…After YB intervention in mice for 16 weeks, the effect on alleviating MetS was evaluated based on MetS serum parameters, hepatic oxidant status markers and gut microbial populations. The results of animal experiment showed that YB intervention attenuated MetS. …”
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High Neutrophil-to-Lymphocyte Ratio Predicts Cardiovascular Mortality in Chronic Hemodialysis Patients by Han Li, Xiangxue Lu, Ruifang Xiong, Shixiang Wang

“…Here we investigated the association between NLR and cardiovascular risk markers, including increased pulse pressure (PP), left ventricular mass index (LVMI) and intima-media thickness (IMT), and mortality in HD patients. …”
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Hepatic Differentiation of Murine Disease-Specific Induced Pluripotent Stem Cells Allows Disease Modelling In Vitro by Reto Eggenschwiler, Komal Loya, Malte Sgodda, Francoise André, Tobias Cantz

“…RT-PCR and immunofluorescence analyses demonstrated the expression of endogenous pluripotency markers. Hepatic precursor cells could be derived from these disease-specific iPSCs applying an in vitro differentiation protocol and could be visualized after transduction of a lentiviral albumin-GFP reporter construct. …”
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Ecotype-Level Genetic Biodiversity of Five Italian Traditional Crops by Francesco Guarino, Stefano Castiglione, Giovanni Improta, Maria Triassi, Angela Cicatelli

“…In particular, we analysed five ecotypes of maize, two of garlic, four of onion, one of escarole, and two of courgette by means of simple sequence repeat (SSR) markers in order to evaluate their level of genetic biodiversity. …”
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Esophageal adenocarcinoma: risk factors and modern screening strategy by I. V. Mayev, D. N. Andreyev, Yu. A. Kucheryavy, M. P. Scheglanova

“…Male gender, Caucasian race, obesity and metabolic syndrome, tobacco smoking, and series of genetic markers are considered to be significant EAC risk factors. …”
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Kidney damage associated with COVID-19: from the acute to the chronic phase by Yannick Mayamba Nlandu, Elliot Koranteng Tannor, Titilope Adetoun Bamikefa, Jean-Robert Rissassi Makulo

“…This review discusses the evidence for renal histological markers of chronicity in COVID-19 patients and triggers of low-grade inflammation that may explain the decline in kidney function in the post-COVID-19 period.…”
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Interferon-γ production in response to the cytotoxic T lymphocyte epitope within an antigen incorporated in simian virus 40 virus-like particles by Takeharu Watanabe, Masayuki Hayashi, Masaaki Arai, Sho Matsushita, Hiroshi Handa, Masaaki Kawano

“…In a previous study, we showed that administration of antigen-incorporated virus-like particles (VLPs) derived from simian virus 40 (SV40) induces production of cytotoxic T lymphocytes (CTL), as well as antibodies against the incorporated antigen(s), without the need for an adjuvant; however, it remains unclear how immune cells recognize and respond to the SV40 capsid because SV40 VLPs did not upregulate expression of maturation markers on dendritic cells. In this study, administration of chicken ovalbumin (OVA) incorporated within SV40 VLPs induced interferon (IFN)-γ production in response to the OVA CTL epitope. …”
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Whole-Exome Sequencing Identifies One De Novo Variant in the FGD6 Gene in a Thai Family with Autism Spectrum Disorder by Chuphong Thongnak, Areerat Hnoonual, Duangkamol Tangviriyapaiboon, Suchaya Silvilairat, Apichaya Puangpetch, Ekawat Pasomsub, Wasun Chantratita, Pornprot Limprasert, Chonlaphat Sukasem

“…Genetic testing such as microarray or sequencing was widely used to identify autism markers, but they are unsuccessful in several cases. …”
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Effect of lactose-free milk powder on lactose intolerance symptoms and nutritional status of pet dogs by Y. Wang, H. Lou, A.M. Turpeinen, L. Liu, F. Xue

“…Lactose intolerance was assessed by faecal composition and pH, water and lactose contents. Biochemical markers for nutritional status were analysed. Feeding intolerance and lactose in faecal samples were observed in dogs fed the standard cow and goat milk powder, but not for the lactose-free milk powder or control groups. …”
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Progression of an Invasive ACTH Pituitary Macroadenoma with Cushing’s Disease to Pituitary Carcinoma by Clarissa Groberio Borba, Rafael Loch Batista, Nina Rosa de Castro Musolino, Vanielle Carvalho Machado, Ana Elisa Evangelista Alcantara, Gilberto Ochman da Silva, Valter Angelo Sperling Cescato, Malebranche Berardo Carneiro da Cunha Neto

“…The difficulty of defining markers for the diagnosis of carcinoma, before metastasis diagnosis, in order to change the management of the disease, is a challenge.…”
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Metabolic reprogramming of glucose: the metabolic basis for the occurrence and development of hepatocellular carcinoma by Kai Wang, Xiaodan Li, Shuwei Guo, Junsheng Chen, Yandong Lv, Zhiqiang Guo, Hongzhou Liu

“…It is characterized by high malignancy, insidious onset, and a lack of specific early diagnostic and therapeutic markers, posing a serious threat to human health. …”
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