A Unique “Composite” PTLD with Diffuse Large B-Cell and T/Anaplastic Large Cell Lymphoma Components Occurring 17 Years after Transplant by Kristin La Fortune, Dahua Zhang, Gordana Raca, Erik A. Ranheim

“…The other component showed anaplastic morphology, expressed some but not all T-cell markers, failed to express most B-cell markers except for PAX5, and was diffusely EBV positive. …”
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Predictive biomarkers of performance under stress: a two-phase study protocol to develop a wearable monitoring system by Cassandra Pattinson, Graham Kerr, Simon S Smith, Chamindie Punyadeera, Ian Stewart, Kerrie Mengersen, Karen A Sullivan, Jonathan M Flintoff, Sarah Ahamed, Shahnewaz Ali, Angus Bagley, Daniel Broszczak, Blair Crewther, Louis de Waal, Shannon L Edmed, Tharindu Fernando, Clinton Fookes, Francesca D Frentiu, Andrew P Hunt, Ottmar V Lipp, Ben McMaster, Luke Ney, Senn L Oon, Ajay Pandey, Parth Pandit, Jonathan M Peake, Muthukuttige Madusha Nuwanthi Perera, Virginie Perlo, Luke Schmidt, Kirsten Spann, Danielle Young, Tony J Parker

“…Biomarkers will be identified from molecular markers in biological samples (eg, blood, saliva, sweat and stool), physiological measures and psychological assessments to predict cognitive and physical performance under stress. …”
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Factors Influencing Oxidative Imbalance in Pulmonary Fibrosis: An Immunohistochemical Study by Simona Inghilleri, Patrizia Morbini, Ilaria Campo, Michele Zorzetto, Tiberio Oggionni, Ernesto Pozzi, Maurizio Luisetti

“…Reactive oxygen species (ROS) and markers of oxidative stress play a pivotal role in human IPF pathology, possibly through induction of epithelial-mesenchymal transition (EMT). …”
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The Initial Months of Antiretroviral Therapy and Its Influence on AGEs, HMGB1, and sRAGE Levels in Asymptomatic HIV-Infected Individuals by Karen Ingrid Tasca, Juliana Trindade Caleffi, Camila Renata Correa, Mariana Gatto, Caio Cavassan de Camargo, Monica Bannwart Mendes, Marjorie de Assis Golim, Mara Biasin, Lenice do Rosário de Souza

“…Because of the current ever-earlier recommendations to start cART and its prolonged use, these and other markers should be investigated in order to monitor and postpone the appearance of non-AIDS comorbidities in PLWHA.…”
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Characteristics of the Endoderm: Embryonic and Extraembryonic in Mouse by Mary Familari

“…In addition, a list of the current markers used to identify these lineages in vivo and in vitro is presented.…”
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Nonalcoholic Steatohepatitis in Nondiabetic Obese Patients by Idilio Zamin, Angelo Alves de Mattos, Cláudio Galeano Zettler

“…BACKGROUND: Nonalcoholic steatohepatitis (NASH) is a major disorder in patients with persistent changes in aminotransferase activity who test negative for viral markers and autoantibodies. Although NASH has been correlated with obesity, no study has been carried out exclusively with nondiabetic obese patients.…”
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Pan-tumor analysis to investigate the obesity paradox in immune checkpoint blockade by Evan J Lipson, Ludmila Danilova, Elizabeth M Jaffee, Won Jin Ho, Mark Yarchoan, Yasser Ged, Jean Hoffman-Censits, Jennifer Durham, Sanjay Bansal, Chester Kao, Rajat Mohindra, Stephanie L Alden, Tanguy Y Seiwert, Soren Charmsaz, Howard L Li, Kabeer Munjal, Hua-Ling Tsai, Alexei Hernandez, Erin M Coyne, Rachel Garonce-Hediger, Laura Tang, Marina Baretti, Kathryn Howe, G Scott Chandler, Madelena Brancati, Aanika Warner, Ervin Griffin, Mari Nakazawa, Chris Thoburn, Jennifer Gizzi, Nicole E Gross, Elsa Hallab, Sarah S Shin, Aditi Guha

“…Obese patients demonstrated lower levels of T effector cells with reduced expression of cytotoxicity markers and higher expression of exhaustion markers at baseline and on-treatment.Conclusions Obese and non-obese patients with cancer have divergent immunological responses to ICIs. …”
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Multiomics unravels the complexity of male obesity: a prospective observational study by Georgios E. Papadakis, Lucie Favre, Yassine Zouaghi, Nathalie Vionnet, Nicolas J. Niederländer, Michela Adamo, James S. Acierno, Dassine Berdous, Alexia Boizot, Jenny Meylan, Julijana Ivanisevic, Emmanuelle Paccou, Hector Gallart-Ayala, Tim Reyns, Elise Van Caeneghem, Bruno Lapauw, Jérôme Pasquier, Yasser Aleman, Styliani Mantziari, Olivier Salamin, Raul Nicoli, Tiia Kuuranne, Tom Fiers, Patric Hagmann, Federico Santoni, Andrea Messina, Nelly Pitteloud

“…In this study, we aimed to discover markers of the severity of metabolic impairment in men with obesity via a multiomics approach. …”
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Correlation and diagnostic significance of CD4 T cell subsets and NLRP3 inflammasome in ulcerative colitis: the role of the NLRP3/T-bet/GATA3 axis by Yingnan Hu, Jingyi Tang, Dian Yu, Shuo Su, Jintao Fang, Linying Xia, Wenjun Xu, Weihan Zhu, Ninping Song, Fengyong Wang, Dechang Diao, Wei Zhang

“…Results UC patients displayed increased Th1 (T-bet, TNF-α), Th2 (GATA3, IL-6), and Th17 (RORγt, IL-17, IL-22, IL-23) markers versus controls. Additionally, Th1 and Th2 cytokines (IL-2 and IL-4) were significantly elevated in severe UC, while Treg markers (FOXP3, IL-10, TGF-β1) were elevated only in mild-to-moderate UC. …”
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Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection by Amanda R. Loehr, Dennis M. Timmerman, Michelle Liu, Ad J. M. Gillis, Melia Matthews, Jordana C. Bloom, Peter K. Nicholls, David C. Page, Andrew D. Miller, Leendert H. J. Looijenga, Robert S. Weiss

“…Current TGCT diagnostics include conventional serum protein markers, but these lack the sensitivity and specificity to serve as accurate markers across all TGCT subtypes. …”
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Alterations of Bone Metabolism in Patients with Diabetes Mellitus by Sain S. Safarova

“…Bone mineral density (BMD) [by dual energy X-ray absorptiometry (DXA)] and serum markers of bone remodeling [aminoterminal propeptide of procollagen type I (P1NP) and c-terminal telopeptide of type I collagen (CTX)], parathyrin, and 25(OH)D were measured in all 235 patients. …”
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Adalimumab (TNFα Inhibitor) Therapy Exacerbates IgA Glomerulonephritis Acute Renal Injury and Induces Lupus Autoantibodies in a Psoriasis Patient by S. S. Wei, R. Sinniah

“…We report a patient with extensive psoriasis presenting with renal failure and seropositive lupus markers without classical lupus nephritis after 18 months treatment with adalimumab. …”
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Clinical Presentation of Preeclampsia and the Diagnostic Value of Proteins and Their Methylation Products as Biomarkers in Pregnant Women with Preeclampsia and Their Newborns by Maria Portelli, Byron Baron

“…For these reasons the search for noninvasive, blood-borne, or urinary biochemical markers that could be used for the screening, presymptomatic diagnosis, and prediction of the development of PE is of great urgency. …”
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Évolution du système alimentaire haut-alpin by Aurélie Rousselot-Pailley

“…This are besides these peculiarities, claimed as markers of local identity, which make the object of a transmission between generations and between social groups. …”
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Effects on Metabolic Health after a 1-Year-Lifestyle Intervention in Overweight and Obese Children: A Randomized Controlled Trial by Maria Waling, Catharina Bäcklund, Torbjörn Lind, Christel Larsson

“…To evaluate the effect of a family-based intervention on anthropometric and metabolic markers in overweight and obese children. Methods. …”
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Human Liver Cells Expressing Albumin and Mesenchymal Characteristics Give Rise to Insulin-Producing Cells by Irit Meivar-Levy, Tamar Sapir, Dana Berneman, Tal Weissbach, Sylvie Polak-Charcon, Philippe Ravassard, Andreas G. Tzakis, Eytan Mor, Camillo Ricordi, Sarah Ferber

“…However, using a lineage-tracing approach, we demonstrate that insulin-producing cells are primarily generated in cells enriched for adult hepatic markers that coexpress both albumin and mesenchymal markers. …”
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Activins and Follistatin in Chronic Hepatitis C and Its Treatment with Pegylated-Interferon-α Based Therapy by Bassem Refaat, Ahmed Mohamed Ashshi, Adel Galal El-Shemi, Esam Azhar

“…Pegylated-interferon-α based therapy for the treatment of chronic hepatitis C (CHC) is considered suboptimal as not all patients respond to the treatment and it is associated with several side effects that could lead to dose reduction and/or termination of therapy. The currently used markers to monitor the response to treatment are based on viral kinetics and their performance in the prediction of treatment outcome is moderate and does not combine accuracy and their values have several limitations. …”
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Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis by Livia Melo Villar, Cristianne Sousa Bezerra, Helena Medina Cruz, Moyra Machado Portilho, Geane Lopes Flores

“…The main objective of this review is to give an insight about the usefulness of oral fluid and DBS for detecting HBV markers. Several groups have evaluated the detection of HBsAg, anti-HBc, and anti-HBs markers in oral fluid and DBS samples demonstrating 13 to 100% of sensitivity and specificity according different groups, sample collectors, and diagnosis assays. …”
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Inflammatory Mechanisms Associated with Skeletal Muscle Sequelae after Stroke: Role of Physical Exercise by Hélio José Coelho Junior, Bruno Bavaresco Gambassi, Tiego Aparecido Diniz, Isabela Maia da Cruz Fernandes, Érico Chagas Caperuto, Marco Carlos Uchida, Fabio Santos Lira, Bruno Rodrigues

“…Inflammatory markers are increased systematically and locally (e.g., skeletal muscle) in stroke patients. …”
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An Escin-loaded Glutaraldehyde-Albumin nanoparticle system for enhancing anticancer activity on lung cancer A549 cells by Murugan Alwarkurichi Munusamy, Muruganantham Bharathi, Abdurahman Hajinur Hirad, Abdullah A. Alarfaj, Samer Hasan Hussein-Al-Ali, Shobana Sampath, Ali Kudumba

“…The expression of apoptotic proteins and oxidative markers increased, while antiapoptotic protein and antioxidant levels were reduced in the albumin-Escin NPs-treated A549 cells. …”
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