Evaluation of the immunological functions of placental alkaline phosphatase in vivo using ALPP transgenic mice by Tse-Ching Chen, Kwai-Fong Ng, Ning Chen, Yi-Ling Pan, Chun-An Cheng, Hsiao-Chun Wu, Yi-Jen Hsueh, Nien-Yi Chiang, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin

“…Alkaline phosphatase (ALP) is a ubiquitously expressed dephosphorylating enzyme and its level in blood is widely used as a diagnosis marker of liver damage or bone disorders in human patients. …”
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Predictors of plasma HDL-C concentrations in the Coronary Artery Risk Development in Young Adults (CARDIA) study by James M. Shikany, John R. Bassler, Jared P. Reis, Pamela J. Schreiner, David T. Redden, John T. Wilkins, Cora E. Lewis

“…HDL-C is an established risk marker for coronary heart disease. We investigated sociodemographic, lifestyle, anthropometric/physiologic, and other predictors of HDL-C over 30 years of follow-up in the Coronary Artery Risk Development in Young Adults (CARDIA) study, a multicenter, longitudinal cohort with a baseline exam in 1985-86 and follow-up exams at least every five years through 2016. …”
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A sensitivity analysis of methodological variables associated with microbiome measurements by Samuel P. Forry, Stephanie L. Servetas, Jennifer N. Dootz, Monique E. Hunter, Jason G. Kralj, James J. Filliben, Scott A. Jackson

“…This report details a full factorial exploration of 48 experimental protocols by systematically varying microbiome sample, iterations of material production, laboratory personnel, DNA extraction kit, marker gene selection, and reference databases. Quantification of the biases associated with each parameter revealed similar magnitudes of variation arising from real biological differences and from varied analysis procedures. …”
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Cerebrospinal Fluid BACE1 Activity and Brain Amyloid Load in Alzheimer's Disease by Timo Grimmer, Panagiotis Alexopoulos, Amalia Tsolakidou, Liang-Hao Guo, Gjermund Henriksen, Behrooz H. Yousefi, Hans Förstl, Christian Sorg, Alexander Kurz, Alexander Drzezga, Robert Perneczky

“…Associations were found in areas close to the brain ventricles, which may have important implications for the use of BACE1 in CSF as a marker for AD pathology and for antiamyloid treatment monitoring.…”
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Effect of Mesenchymal Stem Cells and Platelet-Rich Plasma on the Bone Healing of Ovariectomized Rats by Bo Wei, Chengshuo Huang, Mingyan Zhao, Peng Li, Xiang Gao, Junchao Kong, Yanru Niu, Rui Huang, Juanhua Quan, Jinsong Wei, Jiaqi Chu

“…Moreover, expression levels of osteogenesis-specific marker genes including RUNX2, OSX, and OPN were significantly upregulated in rats treated with PRP and BMSCs compared to those of other groups. …”
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The Effect of Age on Clinical and Laboratory Parameters in Reproductive Age Women with Endometrial Polyps by Aytekin Tokmak, Ebru Ersoy, Ali Özgür Ersoy, Esra Yaşar Çelik, Ali İrfan Güzel, Mustafa Uğur

“…Fasting plasma glucose, basal FSH (follicle stimulating hormone) and estradiol (E2) levels were higher in study group than control group (p<0.05). Mean tumor marker levels were similar in both groups. Complete blood count values, smoking status, presence of PCOS, and number and size of polyps did not differ significantly between the two groups. …”
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Clerodendrum volubile Ethanol Leaf Extract: A Potential Antidote to Doxorubicin-Induced Cardiotoxicity in Rats by Olufunke Esan Olorundare, Adejuwon Adewale Adeneye, Akinyele Olubiyi Akinsola, Daniel Ayodele Sanni, Mamoru Koketsu, Hasan Mukhtar

“…Thus, cardioprotective potential and mechanism(s) of CVE in DOX-induced cardiotoxicity were investigated using cardiac and oxidative stress markers and histopathological endpoints. 50–400 mg/kg/day CVE in 5% DMSO in distilled water were investigated in Wistar rats intraperitoneally injected with 2.5 mg/kg DOX on alternate days for 14 days, using serum troponin I and LDH, complete lipid profile, cardiac tissue oxidative stress marker assays, and histopathological examination of DOX-treated cardiac tissue. …”
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Metatranscriptomes-based sequence similarity networks uncover genetic signatures within parasitic freshwater microbial eukaryotes by Arthur Monjot, Jérémy Rousseau, Lucie Bittner, Cécile Lepère

“…Conclusions Although no universal marker for parasitism was identified, candidate genes can be proposed at a fine taxonomic scale. …”
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655Val and 1170Pro ERBB2 SNPs in Familial Breast Cancer Risk and BRCA1 Alterations by Stefania Tommasi, Vita Fedele, Rosanna Lacalamita, Michele Bruno, Francesco Schittulli, David Ginzinger, Gery Scott, Serenella Eppenberger-Castori, Daniele Calistri, Silvia Casadei, Ian Seymour, Salvatore Longo, Gianluigi Giannelli, Brunella Pilato, Giovanni Simone, Christopher C. Benz, Angelo Paradiso

“…One of these, Ile655Val, introduces a structural change in the transmembrane region of ERBB2 and has been the focus of debate over its potential role as a susceptibility marker for breast cancer risk. Another SNP, Ala1170Pro, introduces a structural change in the carboxyl-terminal regulatory domain of the protein, but its clinical and biological importance remains undefined. …”
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Construction of prokaryotic system for expression of porcine circovirus type 2 ORF-2 gene fragment by A. G. Galeeva, A. R. Akhunova, K. V. Usoltsev, N. I. Khammadov, M. A. Efimova

“…The transformants were selected based on the marker gene of ampicillin resistance on a selective medium. …”
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Significantly Elevated Serum Lipase in Pregnancy with Nausea and Vomiting: Acute Pancreatitis or Hyperemesis Gravidarum? by Amanda Johnson, Bethany Cluskey, Nina Hooshvar, Daphne Tice, Courtney Devin, Elaine Kao, Suhalia Nawabi, Steven Jones, Lihua Zhang, Chi Dola

“…Although significantly elevated lipase level in pregnant patients with nausea and vomiting is a concern for acute pancreatitis, these two cases of significantly elevated serum lipase without other clinical findings of pancreatitis led to this report that serum lipase could be quite elevated in hyperemesis gravidarum and that it might not be an accurate biochemical marker for acute pancreatitis. Imaging studies are thus necessary to establish the diagnosis of acute pancreatitis.…”
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Predictive value of systemic immune inflammation index combined with coagulation index in traumatic coagulopathy in patients with severe trauma by Chen Wang, Yongyong Huang, Shiyun Liao, Jiming Song

“…The systemic immune inflammation index (SII), a composite marker of inflammation and immune response, alongside conventional coagulation indices, may hold promise in predicting TIC. …”
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Association between P2X7 Receptor Polymorphisms and Bone Status in Mice by Susanne Syberg, Peter Schwarz, Solveig Petersen, Thomas H. Steinberg, Jens-Erik Beck Jensen, Jenni Teilmann, Niklas Rye Jørgensen

“…The strains were compared by means of dual energy X-ray absorptiometry (DXA), bone markers, and three-point bending. Cultured osteoclasts were used in the ATP-induced pore formation assay. …”
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Particle-bound PAHs and Chemical Composition, Sources and Health Risk of PM2.5 in a Highly Industrialized Area by Elizabeth Vega, Diego López-Veneroni, Omar Ramírez, Judith C. Chow, John G. Watson

“…The derived factors were associated with sources based on marker species resulting in heavy-oil combustion (22% of variance), vehicle engine exhaust (13–19% of variance), fugitive dust (18% of variance), biomass burning (9–13% of variance), secondary aerosols (14% of variance), and industrial emissions (6–10% of variance). …”
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Decrease in HBsAg After TAF Switching from Entecavir During Long-Term Treatment of Chronic Hepatitis B Virus Infection by Kazuto Tajiri, Yuka Hayashi, Aiko Murayama, Nozomu Muraishi, Masami Minemura, Ichiro Yasuda

“…The most significant factor associated with achieving HBsAg < 100 IU/mL was the Fib-4 index, a marker of liver fibrosis, at the time of switching. …”
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Elevated Plasma Level of 8-Hydroxy-2′-deoxyguanosine Is Associated with Primary Open-Angle Glaucoma by Altaf A. Kondkar, Taif A. Azad, Tahira Sultan, Essam A. Osman, Faisal A. Almobarak, Saleh A. Al-Obeidan

“…To determine the association between plasma 8-hydroxy-2′-deoxyguanosine (8-OHdG) levels, a marker for oxidative DNA damage, and patients with primary open-angle glaucoma (POAG) or its clinical phenotypes. …”
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A Real-Time Human Pose Measurement System for Human-In-The-Loop Dynamic Simulators by Nicola Giulietti, Davide Todesca, Marco Carnevale, Hermes Giberti

“…This study presents a vision-based, marker-less measurement system for real-time 3D human pose estimation. …”
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Effects of Prognostic Nutrition Index, Neutrophil/Lymphocyte Ratio, and C-reactive Protein/Albumin Ratio on Prognosis Undergoing Open Heart Surgery by Anil Kilinc, Nilay Tas, Melih Urkmez, Ebru Canakci, Ilker Coskun, Merve Elif Demirhan

“…The other variables showed no significant effects on intensive care duration, total hospitalization, and 30-day mortality rates. Conclusion: PNI, a marker of inflammatory and immune processes, may be a beneficial variable for estimating postoperative prognosis among patients undergoing open heart surgery.…”
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Caudal vena cava isolation using ablation index‐guided radiofrequency catheter ablation (CARTO™ 3) to treat sustained atrial tachycardia in horses by Eva Buschmann, Glenn Van Steenkiste, Ingrid Vernemmen, Marie Demeyere, Stijn Schauvliege, Annelies Decloedt, Gunther vanLoon

“…Caudal vena cava isolation guided by the ablation index, a lesion quality marker incorporating power, duration and contact force, might improve outcome. …”
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Effect Of Exercise Therapy on Lipid Profile and Oxidative Stress Indicators in Patients with Type 2 Diabetes by Madeeha Jadoon, Shazia Zeb, Sajid Razaq, Munazza Khan, Muhammad Shoaib, Sara Mariyum

“…Additionally, oxidative stress indicators improved: Apropos to this, serum MDA, a marker of oxidative stress, significantly reduced (p = 0. 012). …”
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