Knockdown of RFC4 inhibits cell proliferation of oral squamous cell carcinoma in vitro and in vivo by Pengyue You, Di Wang, Zheng Liu, Shuzhen Guan, Ning Xiao, Haotian Chen, Xin Zhang, Lichuan Wu, Guizhen Wang, Haitao Dong

“…Overall, the present study reveals that RFC4 may play a pivotal role in OSCC tumorigenesis and could serve as a potential predictive marker for the efficacy of immunotherapy.…”
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Preferential Expression of B7-H6 in Glioma Stem-Like Cells Enhances Tumor Cell Proliferation via the c-Myc/RNMT Axis by Hanqing Chen, Yundi Guo, Jing Sun, Jun Dong, Qinghua Bao, Xueguang Zhang, Fengqing Fu

“…Here, we show that B7-H6 expression is abnormally upregulated in glioma tissue and that B7-H6 is coexpressed with stem cell marker Sox2. Intriguingly, B7-H6 was rarely detected on the surface of glioma cell lines but was abundantly expressed in glioma stem-like cells (GSLCs) that were derived from the glioma cell lines in vitro. …”
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Predicting the Development of Gastric Neoplasms in a Healthcare Cohort by Combining Helicobacter pylori Antibodies and Serum Pepsinogen: A 5-Year Longitudinal Study by Min-Sun Kwak, Goh Eun Chung, Su Jin Chung, Seung Joo Kang, Jong In Yang, Joo Sung Kim

“…We evaluated whether the combination of serum HP antibody and pepsinogen (PG), which is indicative of gastric atrophy, could serve as a predictive marker for the development of gastric neoplasms in a Korean population. …”
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Single-cell sequencing provides clues about the developmental genetic basis of evolutionary adaptations in syngnathid fishes by Hope M Healey, Hayden B Penn, Clayton M Small, Susan Bassham, Vithika Goyal, Micah A Woods, William A Cresko

“…We created a single-cell RNA sequencing atlas of Gulf pipefish embryos to understand the developmental basis of four traits: derived head shape, toothlessness, dermal armor, and male pregnancy. We completed marker gene analyses, built genetic networks, and examined the spatial expression of select genes. …”
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Mechanistic elucidation of human pancreatic acinar development using single-cell transcriptome analysis on a human iPSC differentiation model by Atsushi Mima, Azuma Kimura, Ryo Ito, Yu Hatano, Hiraku Tsujimoto, Shin-Ichi Mae, Junko Yamane, Wataru Fujibuchi, Norimitsu Uza, Taro Toyoda, Hiroshi Seno, Kenji Osafune

“…Single-cell RNA-seq analysis of the retrieved grafts confirmed the differentiation of pancreatic acinar lineage cells and identified REG4 as a candidate marker for pancreatic acinar progenitor cells. Furthermore, differential gene expression analysis revealed upregulated pathways, including cAMP-related signals, involved in the differentiation of hiPSC-derived pancreatic acinar lineage cells in vivo, and we found that a cAMP activator, forskolin, facilitates the differentiation from hiPSC-derived pancreatic endoderm into pancreatic acinar progenitor cells in our in vitro differentiation culture. …”
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The Upregulation of COX2 in Human Degenerated Nucleus Pulposus: The Association of Inflammation with Intervertebral Disc Degeneration by Chang Liu, Guoyan Liang, Zhantao Deng, Jing Tan, Qiujian Zheng, Feng-Juan Lyu

“…We previously found upregulated markers of fibrosis, the late stage of chronic inflammation, in degenerated IVD with a small number of clinical specimens. …”
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Pendidikan keluarga dan riyadhah dalam pembentukan karakter penelitian terhadap pengamal tarekat Qodiriyah Naqsyabandiyah pondok pesantren Suryalaya Tasikmalaya by Sunarno Sunarno, Edwin Hadiyan, Suhrowardi Suhrowardi, Soni Sonjaya

“…Nilai-nilai karakter yang terdapat dalam ajaran TQN Pondok Pesantren Suryalaya, yang tidak terdapat dalam permen diknas yang 18, yaitu : (a). kesadaran diri, (b). pengenalan diri, (c). pengendaliah diri, (d). kesadaran akan adanya Allah yang maha segalanya, (e). kesadaran hati sebagai alat menghadap Allah, (f). rasa cinta kepada Allah, (g). rasa syukur kepada Allah, dan h. ikhlash dan istikomah.( 9). …”
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Differentiating Apical and Basal Left Ventricular Aneurysms Using Sphericity Index: A Clinical Study by Slobodan Tomić, Stefan Veljković, Armin Šljivo, Dragana Radoičić, Goran Lončar, Milovan Bojić

“…Surgical ventricular reconstruction (SVR) compensates for L-axis reduction, with preservation of the L axis critical for achieving a more physiological shape. SI thus serves as a marker for left ventricular geometry and surgical outcomes.…”
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Intestinal Organoids in Colitis Research: Focusing on Variability and Cryopreservation by Talke F. zur Bruegge, Andrea Liese, Sören Donath, Stefan Kalies, Maike Kosanke, Oliver Dittrich-Breiholz, Sandra Czech, Verena N. Bauer, André Bleich, Manuela Buettner

“…First, to analyze the impact of antibiotics/antimycotics, we performed kinetic experiments using ZellShield® and measured the gene expression levels of the tight junction markers Ocln, Zo-1, and Cldn4, the proliferation marker Ki67, and the proinflammatory cytokine Tnfα. …”
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Diagnostic Potential of Systemic Eosinophil-Associated Cytokines and Growth Factors in IBD by Katarzyna Neubauer, Malgorzata Matusiewicz, Iwona Bednarz-Misa, Sabina Gorska, Andrzej Gamian, Malgorzata Krzystek-Korpacka

“…GM-CSF, in turn, demonstrated to be an excellent indicator of bowel inflammation and may be taken into consideration as a noninvasive marker of mucosal healing. In summary, eosinophil-associated cytokines are elevated in IBD, more pronouncedly in UC, and may support the differential diagnosis of IBD and aid in monitoring of mucosal healing.…”
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Comparative analysis of viability, proliferation, and mineralization potential of human pulp and osteoblastic cells exposed to different bioceramic endodontic sealers by Marcos Coelho Santiago, Gustavo Henrique de Oliveira Salles, Gustavo Gomes de Lima, Laudimar Alves de Oliveira, Loise Pedrosa Salles

“…The ALP activity, an early marker of osteogenesis, was higher in hDPCs exposed to NEOMTA-P, while the osteoblastic cells showed higher ALP when exposed to AHP-B. …”
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Connections Across Open Water: A Bi‐Organelle, Genomics‐Scale Assessment of Atlantic‐Wide Population Dynamics in a Pelagic, Endangered Apex Predator Shark (Isurus oxyrinchus) by Andrea M. Bernard, Marissa R. Mehlrose, Kimberly A. Finnegan, Bradley M. Wetherbee, Mahmood S. Shivji

“…Complete mitochondrial genome (mitogenome) sequences and genome‐wide SNPs from sharks distributed across the Atlantic revealed contrasting patterns of population structure across marker types. Consistent with this species' long‐distance migratory capabilities, SNPs showed high connectivity and Atlantic panmixia overall. …”
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The Effects of Hyperacute Serum on the Elements of the Human Subchondral Bone Marrow Niche by Melinda Simon, Bálint Major, Gabriella Vácz, Olga Kuten, István Hornyák, Adél Hinsenkamp, Dorottya Kardos, Marcell Bagó, Domonkos Cseh, Adrienn Sárközi, Denes Horvathy, Stefan Nehrer, Zsombor Lacza

“…Viability measurements, RT-qPCR evaluation for gene expression and flow cytometry for cell surface marker analysis were performed to compare the effects of FCS-, PRP-, or HAS-supplemented culture media. …”
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Extracellular volume fraction and native T1 mapping in diabetic cardiomyopathy: a comprehensive meta-analysis by Ahmed Marey, Ali Alabdullah, Hossam Ghorab, Fatima Ali, Jawdat Abdulla, Akhil Narang, Muhammad Umair

“…Conclusions ECV is a promising marker for quantifying MF in T2DM, demonstrating significant differences between diabetics and controls. …”
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Quarantine nematode species and pathotypes potentially dangerous for domestic potato production: populations diversity and the genetics of potato resistance by N. V. Mironenko, T. A. Gavrilenko, A. V. Khiutti, O. S. Afanasenko

“…The results of molecular research on revealing the polymorphisms of loci involved in the control of resistance to cyst and gall nematodes, the development of molecular markers of certain genes and their use in marker-assisted selection for developing of new resistant cultivars, including those with group resistance, are considered.…”
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Dietary and plasma atherogenic and thrombogenic indices and cardiometabolic risk factors among overweight and individuals with obesity by Reyhaneh Mokhtari, Mahdieh Abbasalizad Farhangi

“…Apart from dyslipidemia, the Atherogenic Index of Plasma (AIP), which is associated with dietary consumption, is another marker for predicting the risk of CVD. Healthy fat quality indicators may impact AIP. …”
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Identification of Heat-Responsive Genes in Guar [Cyamopsis tetragonoloba (L.) Taub] by Aref Alshameri, Fahad Al-Qurainy, Abdel-Rhman Gaafar, Salim Khan, Mohammad Nadeem, Saleh Alansi

“…These results will provide a good start to dissect the molecular behaviour of plants induced by heat stress and could identify the key genes in stress response for marker-assisted selection in Guar and reveal their roles in stress adaptation in plants.…”
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Immunohistochemical Coexpression of Epithelial Cell Adhesion Molecule and Alpha-Fetoprotein in Hepatocellular Carcinoma by Leonardo do Prado Lima, Carla Jorge Machado, João Bernardo Sancio Rocha Rodrigues, Leonardo de Souza Vasconcellos, Eduardo Paulino Junior, Paula Vieira Teixeira Vidigal, Vivian Resende

“…The epithelial cell adhesion molecule (EpCAM) has been proposed as a marker for cancer stem cells in human hepatocellular carcinoma (HCC) as well as in the development of novel target therapies. …”
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GPX4 expression changes in proximal tubule cells highlight the role of ferroptosis in IgAN by Jianbo Qing, Lijuan Zhang, Ru Fan, Huiwen Zhi, Changqun Li, Yaheng Li, Junnan Wu, Chongyang Han, Yafeng Li

“…These findings demonstrate that ferroptosis inhibition may be a potential mechanism to alleviate OS injury in IgAN, and GPX4 could not only function as a specific marker for PTCs in IgAN but also represent a potential therapeutic target to halt the progression of the disease.…”
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Automated and code-free development of a risk calculator using ChatGPT-4 for predicting diabetic retinopathy and macular edema without retinal imaging by Eun Young Choi, Joon Yul Choi, Tae Keun Yoo

“…Logistic regression analysis was performed by ChatGPT-4 to predict DR and DME, followed by the automatic generation of Hypertext Markup Language (HTML) code for the web-based tool. …”
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