-
2741
Symmetric Dimethylarginine Is Not Associated with Cumulative Inflammatory Load or Classical Cardiovascular Risk Factors in Rheumatoid Arthritis: A 6-Year Follow-Up Study
Published 2015-01-01“…SDMA did not relate to CV disease risk factors in our population and its clinical significance as a surrogate marker of endothelial dysfunction in patients with RA remains to be determined.…”
Get full text
Article -
2742
Identification of retinol dehydrogenase 10 as a shared biomarker for metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus
Published 2025-01-01“…Similarly, serum levels of RDH10 were significantly lower in MASLD and T2DM model mice and humans than in controls.ConclusionOur study suggests that RDH10 is a common diagnostic marker for MASLD and T2DM and provides new research directions for the prevention and treatment of MASLD and T2DM.…”
Get full text
Article -
2743
Cystatin C Secretion in Blood Derivatives and Cellular Models of Idiopathic Parkinson’s Disease
Published 2025-01-01“…No statistically significant differences in cystatin C concentrations were found between the subjects in any of the biospecimen types. As a personalized marker, a higher cystatin C concentration was shown for some individual patients in the culture medium of midbrain organoids, suggesting a potential involvement in Parkinson’s disease physiopathology. …”
Get full text
Article -
2744
Anti-Inflammatory and Antioxidant Effects of Aqueous Extract on the Liver and Kidney of PCOS Mice
Published 2025-01-01“…Serum liver and kidney biochemical markers, levels of oxidative stress, and two pro-inflammatory markers were measured. …”
Get full text
Article -
2745
Development of volatiles and odor-active compounds in Chinese dry sausage at different stages of process and storage
Published 2021-05-01“…Level of heptanal, 1-octen-3-ol, the ethyl of 2-methylbutanoic, 3-methylbutanoic, butanoic, benzoic, hexanoic, heptanoic, octanoic and decanoic acid were best discriminators of process stage, while (E)-2-nonenal, ethyl hexanoate, ethyl heptanoate, and methyl decanoate, were marker compounds of storage time. An objective method was established to evaluate the stages of process and storage for samples.…”
Get full text
Article -
2746
Histological diagnosis of primary biliary cholangitis in one patient without cholestasis alterations: a case report that escaped guidelines
Published 2024-01-01“…However, many patients with these characteristics have been diagnosed with PBC disease only histologically, mainly patients with normal ALP and elevated gamma-glutamyl transferase (GGT), whose normalization has been used as a marker for the follow-up. In contrast, this is the case of a patient with autoantibody positivity and both ALP and GGT within the range, diagnosed for PBC by histology. …”
Get full text
Article -
2747
Identification of quantitative trait loci of pod dehiscence in a collection of soybean grown in the southeast of Kazakhstan
Published 2024-09-01“…The genotyping of the collection using a DNA marker for the Pdh1 gene, a major gene for PD, revealed that 244 accessions had the homozygous R (resistant) allele, 14 had the homozygous S (susceptible) allele, and 15 accessions showed heterozygosity. …”
Get full text
Article -
2748
N6-Methyladenosine in RNA and DNA: An Epitranscriptomic and Epigenetic Player Implicated in Determination of Stem Cell Fate
Published 2018-01-01“…Among the base modification markers extensively studied, 5-methylcytosine (5-mC) and its oxidative derivatives (5-hydroxymethylcytosine (5-hmC), 5-formylcytosine (5-fC), and 5-carboxylcytosine (5-caC)) dynamically occur in DNA and RNA and have been acknowledged as important epigenetic markers involved in regulation of cellular biological processes. …”
Get full text
Article -
2749
The mitochondrial gene order and CYTB gene evolution in insects
Published 2017-05-01“…Mitochondrial DNA genes (mtDNA) are quite often used as markers for phylogenetic research into many organisms including arthropods, because mtDNA is multicopied, is inherited maternally, does not undergo recombination and accumulates mutations quickly enough (relative to the nuclear genome). …”
Get full text
Article -
2750
The Application of Supervised Machine Learning Algorithms for Image Alignment in Multi-Channel Imaging Systems
Published 2025-01-01“…The images from the calibration setup in each channel determine the coordinates of the markers, and the displacements of the marker centers in the system’s channels relative to the coordinates of the centers in the reference channel are then determined. …”
Get full text
Article -
2751
Genome-Wide Association Study towards Genomic Predictive Power for High Production and Quality of Milk in American Alpine Goats
Published 2020-01-01“…Validation towards the development of marker-based selection that provides precision breeding methods will thereby increase the breeding value.…”
Get full text
Article -
2752
In Vivo Healing Potential of Aegle marmelos in Excision, Incision, and Dead Space Wound Models
Published 2014-01-01“…AME was studied for its wound breaking strength (incision wound), rate of contraction, period of epithelization and histology of skin (excision model), and granulation tissue free radicals, antioxidants, acute inflammatory marker, and connective tissue markers and deep connective tissue histology (dead space wound). …”
Get full text
Article -
2753
Deep learning classification of MGMT status of glioblastomas using multiparametric MRI with a novel domain knowledge augmented mask fusion approach
Published 2025-01-01“…MGMT methylation status of glioblastoma is an important prognostic marker and is also important for treatment decisions. …”
Get full text
Article -
2754
Zone Specific Fractal Dimension of Retinal Images as Predictor of Stroke Incidence
Published 2014-01-01“…A new methodology to measure FD of a specific zone in retinal images has been developed and tested as a marker for stroke prediction. Higuchi’s fractal dimension was measured in circumferential direction (FDC) with respect to optic disk (OD), in three concentric regions between OD boundary and 1.5 OD diameter from its margin. …”
Get full text
Article -
2755
Monocyte‐predominant engraftment, cytokine levels and early transplant‐related complications in pediatric hematopoietic stem cell recipients
Published 2019-03-01“…However, to date, sufficiently specific and sensitive diagnostic markers for the various forms of VES have not been identified. …”
Get full text
Article -
2756
A Case of Fibrous Pseudotumor in the Scrotum: Challenge for Diagnosis and Testicular Preservation
Published 2018-01-01“…Computed tomography and magnetic resonance imaging revealed paratesticular tumors. Testicular tumor marker levels were within normal limits. We scheduled the patient to undergo tumor biopsy combined with intraoperative rapid diagnosis. …”
Get full text
Article -
2757
Unraveling Community Potential Interactions by Environmental DNA in the Hong Kong Coastal Waters
Published 2024-11-01“…In this study, we employed environmental DNA (eDNA) metabarcoding, utilizing multiple marker genes, to comprehensively investigate interspecific interactions across various domains in the subtropical coastal waters of Hong Kong. …”
Get full text
Article -
2758
TIM-3 and TIM-1 Could Regulate Decidual γδTCR Bright T Cells during Murine Pregnancy
Published 2019-01-01“…In addition, compared to peripheral γδT lymphocytes, a greater proportion of decidual γδT cells expressed the cytotoxic marker CD107a and markers of Th1 or Th2 polarization (TIM-3, TIM-1), where decidual γδTCRbright cells were characterized by high TIM-3 and TIM-1 receptor expression. …”
Get full text
Article -
2759
Modern issues of sugar beet (<i>Beta vulgaris</i> L.) hybrid breeding
Published 2021-07-01“…Testing of the OP-S4 marker’s being in the same linkage group as the genes responsible for expression of the economically valuable trait monogermity demonstrates its relative reliability. …”
Get full text
Article -
2760
Sample Size and Statistical Power Calculation in Genetic Association Studies
Published 2012-06-01“…An analysis using a larger number of markers requires a larger sample size. Testing a single-nucleotide polymorphism (SNP) marker requires 248 cases, while testing 500,000 SNPs and 1 million markers requires 1,206 cases and 1,255 cases, respectively, under the assumption of an odds ratio of 2, 5% disease prevalence, 5% minor allele frequency, complete linkage disequilibrium (LD), 1:1 case/control ratio, and a 5% error rate in an allelic test. …”
Get full text
Article