Modelling Hollow Microneedle-Mediated Drug Delivery in Skin Considering Drug Binding by Tanmoy Bhuimali, Sarifuddin, Diganta Bhusan Das, Prashanta Kumar Mandal

“…<b>Methods:</b> The governing equations representing the flow of interstitial fluid, the transport of verapamil in the viable skin and the concentrations in the blood and tissue compartments are solved using combined Marker and Cell and Immersed Boundary Methods to gain a quantitative understanding of the model under consideration. …”
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The Potential of Antibodies Against the Phosphatidylserine / Prothrombin Complex as a Biomarker in Antiphospholipid Syndrome by Piotr Pasek, Witold Czyż, Julia Kulbacka, Julia Kacperczyk, Marta Chuncia-Ileczko, Michalina Wójcikiewicz, Filip Arczewski, Karol Dziedzic, Maciej Wojszczyk, Damian Zys, Julia Ryniecka

“…Testing for aPS/PT, in conjunction with other APS markers, is recommended to assess the risk of thrombotic events. …”
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Demand and Status of a Scientific Degree in the Non-Academic Labour Market: Regional Case by O. S. Ivanchenko, V. V. Sych

“…As a result of the study it was established that: in employment a scientific degree does not give competitive advantages to the applicant; a scientific degree has no value in the non-academic labour market, does not contribute to the advancement and occupation of a higher position in the enterprise; a scientific degree and the presence of employees with a scientific degree in the staff are considered as image-building, status marker and reputation capital of the enterprise; employers have stereotypes regarding scientific employees, which are associated both with the individual organization of labour processes and the compatibility of the scientific, creative and production process; the non-academic sector lacks a human resources strategy for dealing with such employees and a system of their incentives. …”
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A Diet Enriched in Docosahexanoic Acid Exacerbates Brain Parenchymal Extravasation of Apo B Lipoproteins Induced by Chronic Ingestion of Saturated Fats by Menuka M. Pallebage-Gamarallage, Virginie Lam, Ryusuke Takechi, Susan Galloway, John C. L. Mamo

“…The plasma concentration of brain-derived S100𝛽 was measured as a marker of cerebrovascular inflammation. In mice fed SFA for 3 months, provision thereafter of a DHA-enriched diet exacerbated parenchymal apo B retention, concomitant with a significant increase in plasma cholesterol. …”
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Establishment of Novel Limbus-Derived, Highly Proliferative ABCG2+/ABCB5+ Limbal Epithelial Stem Cell Cultures by Eung Kweon Kim, Ga-Hyun Lee, Boram Lee, Yong-Sun Maeng

“…These LESCs exhibited the LESC marker profile and differentiated into corneal epithelial cells. …”
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Il-6 signaling exacerbates hallmarks of chronic tendon disease by stimulating reparative fibroblasts by Tino Stauber, Greta Moschini, Amro A Hussien, Patrick Klaus Jaeger, Katrien De Bock, Jess G Snedeker

“…In human tendinopathic tendons, we also confirm the strong presence and co-localization of IL-6, IL-6R, and CD90, an established marker of reparative fibroblasts. To dissect the underlying causalities, we combine IL-6 knock-out mice with an explant-based assembloid model of tendon damage to successfully connect IL-6 signaling to reparative fibroblast activation and recruitment. …”
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Procoagulant Phospholipids and Tissue Factor Activity in Cerebrospinal Fluid from Patients with Intracerebral Haemorrhage by Patrick Van Dreden, Guy Hue, Jean-François Dreyfus, Barry Woodhams, Marc Vasse

“…TFa measurement in the CSF of patients with ICH could constitute a new prognostic marker.…”
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<i>Turbat al-Ḥusayn</i>: Modern Presentation of an Early Shīʿī Practice by S. M. Hadi Gerami, Zinab Aghagolizadeh

“…During the Safavid era, <i>turbat</i> became institutionalized as a marker of Shīʿī identity, with its economic significance expanding through the production of prayer tablets and rosaries. …”
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The protective effect of dietary flavonoid fraction from Acanthophora spicifera on streptozotocin induced oxidative stress in diabetic rats by Lavakumar Vuppalapati, Ravichandiran Velayudam, K.F.H. Nazeer Ahamed, Sowmya Cherukuri, Bhaskar Reddy Kesavan

“…The antioxidant consequences of FRF on STZ-induced diabetic rats were determined by the estimations of the oxidative stress marker like malonyldialdehyde and antioxidant enzymes such as superoxide dismutase, catalase and glutathione in tissue homogenates of heart, liver and kidney. …”
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Breast Carcinoma, Intratumour Heterogeneity and Histological Grading, Using Geostatistics by Vénus Sharifi‐Salamatian, Anne de Roquancourt, Jean Paul Rigaut

“…The assessment of a genetic marker for human tumours requires quantifiable measures of intratumoral heterogeneity. …”
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Distribution, Size, and Shape of Abdominal Aortic Calcified Deposits and Their Relationship to Mortality in Postmenopausal Women by Melanie Ganz, Marleen de Bruijne, Erik B. Dam, Paola Pettersen, Morten A. Karsdal, Claus Christiansen, Mads Nielsen

“…We investigated whether size, shape, and distribution of AACs are related to mortality and how such prognostic markers perform compared to the state-of-the-art AC24 marker introduced by Kauppila. …”
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Relative Fat Mass, A Better Predictor of Erectile Dysfunction: Insights From the NHANES 2001–2004 by BoWen Yang, HanYu Wang, Luyi Tang, JiuHuan Feng, ShuFang Hou

“…Our findings suggest that higher RFM levels are associated with an increased risk of ED, highlighting its potential utility as a predictive marker for this condition.…”
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Evaluation of Serum Zonulin Level and Intestinal Permeability in Patients with Chronic Spontaneous Urticaria and the Relationship Between Serum Zonulin Level and Disease Severity by Simge Ünal, Selda Pelin Kartal, Ahmet Ozsoy, Fevzi Nuri Aydın

“…Objective: This study aimed to investigate the role of intestinal permeability in the etiopathogenesis of CSU by measuring serum zonulin levels, a marker of intestinal permeability, in both CSU patients and control subjects. …”
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Serum Nerve Growth Factor Levels as a Predictor of Bull Candidate Semen Quality of Madura Cattle by Rimayanti Rimayanti, Nurul Azizah, Pudji Srianto, Sri Pantja Madyawati, Trilas Sardjito, Imam Mustofa

“…Therefore, NGF levels could be used as a marker of male fertility in Madura bull cattle candidates. …”
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Naked barley: taxonomy, breeding, and prospects of utilization by K. A. Lukina, O. N. Kovaleva, I. G. Loskutov

“…Hypotheses on the centers of its origin are discussed using DNA marker data. The main areas of its cultivation are shown, along with possible reasons for such a predominating or exclusive distribution of naked barley in highland areas. …”
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A study on the production of extracellular vesicles derived from novel immortalized human placental mesenchymal stromal cells by Yingying Tong, Jie Sun, Xin Jiang, Xu Jia, Huimin Xiao, Hua Wang, Guanghua Yang

“…Our findings indicate that the immortalization process preserves the particle size, quantity and surface marker profiles of EVs, providing a possible approach to produce high-yield EVs suitable for disease diagnosis and treatment.…”
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Selective Activation of Cancer Stem Cells by Size-Specific Hyaluronan in Head and Neck Cancer by Marisa Shiina, Lilly Y. W. Bourguignon

“…First, we observed that 200 kDa-HA (but not other sizes of HA) preferentially induces certain stem cell marker expression resulting in self-renewal and clonal formation of these cells. …”
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The Microbial Activity in PM2.5 in Indoor Air: As an Index of Air Quality Level by Hanlin Chen, Rui Du, Weishan Ren, Sujian Zhang, Pengrui Du, Yongtao Zhang

“…Thus, this study used a modified technique of fluorescein diacetate (FDA) hydrolysis to evaluate the activity of microorganisms in the PM2.5 during three seasons (summer, autumn and winter) in Beijing. 0.155–5.388 ng m−3 and 0.091–5.740 ng m−3 of sodium fluorescein, a marker of microbial activity, were measured indoors and outdoors, respectively; thus, no significant difference in concentration between the two environments was detected, but the indoor activity was affected by outdoor conditions to an extent. …”
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Extracellular cold-inducible RNA-binding protein in CNS injury: molecular insights and therapeutic approaches by Dmitriy Lapin, Archna Sharma, Ping Wang

“…We also explore eCIRP’s potential as a prognostic marker of CNS injury severity and outcome. Next, we provide an overview of eCIRP-targeting therapeutics and suggest strategies to develop these agents to ameliorate CNS injury. …”
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Multisystem inflammatory syndrome in children with COVID-19 in a multitransfused patient by Swarnalata Das, Manas Behera Ranjan, Palash Das

“…Ferritin is an acute phase reactant which is used as a marker of inflammation. Diagnosis of MIS-C in the background of transfusion dependent thalassemia with iron overload needs a strong clinical suspicion. …”
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