The Clostridium difficile cell wall protein CwpV is antigenically variable between strains, but exhibits conserved aggregation-promoting function. by Catherine B Reynolds, Jenny E Emerson, Lucia de la Riva, Robert P Fagan, Neil F Fairweather

“…CwpV is the largest member of this family and is expressed in a phase variable manner. Here we show CwpV promotes C. difficile aggregation, mediated by the C-terminal repetitive domain. …”
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GEOPOLITICAL VARIATION IN THE REPORTAGE OF SECURITY BY THE NATION AND DAILY TRUST NEWSPAPERS (2010-2020): A PROGNOSIS by M. M. NURUDDEN, M. M. NURUDDEN

“…The two national dailies are expected to be nationalistic and report security issue in an objective manner instead of framing narratives that can exacerbate tension. …”
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Developmental changes of skin quality from breast, back, and thigh of Pekin ducks from 1 to 6 weeks of age by Hao Li, Wenxuan Zheng, Shuo Xin, Ye Hui, Yijun Zhu, Xi Lin, Huaqi Zhang, Yongwen Zhu

“…In conclusion, the developmental pattern of skin growth and structure of Pekin ducks in a linear manner with increased age. The skin quality was increased in a quadratic manner, which was associated with the changes in mRNA expression of target genes related to cell proliferation and collagen synthesis.…”
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The Anti-Inflammatory Effects of Shinbaro3 Is Mediated by Downregulation of the TLR4 Signalling Pathway in LPS-Stimulated RAW 264.7 Macrophages by Hwa-Jin Chung, Wonil Koh, Won Kyung Kim, Joon-Shik Shin, Jinho Lee, Sang Kook Lee, In-Hyuk Ha

“…In the present study, Shinbaro3 inhibited NO generation in LPS-induced RAW 264.7 cells in a dose-dependent manner. Shinbaro3 also downregulated the mRNA and protein expression of inflammatory mediators in a dose-dependent manner. …”
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Solanum Procumbens-Derived Zinc Oxide Nanoparticles Suppress Lung Cancer In Vitro through Elevation of ROS by Ibrahim Ibrahim Abdel Aziz, Almaimani A. Riyad, Almasmoum A. Hussian, Ghaith M. Mazen, Moorthy Kannaiyan

“…On the other hand, the SP-ZnONPs decrease nitric oxide level in A549 cells in a dose-dependent manner, which also supports the apoptosis. In conclusion, SP-ZnONPs would become a promising treatment option for lung cancer.…”
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Deregulated JNK signaling enhances apoptosis during hyperthermia by Atsushi Enomoto, Takemichi Fukasawa, Hiroshi Terunuma, Keiichi Nakagawa, Ayumi Yoshizaki, Shinichi Sato, Noriko Hosoya, Kiyoshi Miyagawa

“…Despite the reduced or transient phosphorylation of ASK1, MLK3, or SEK1, downstream JNK was phosphorylated in a temperature-dependent manner. In vitro kinase assays demonstrated that heat did not directly stimulate SEK1 or JNK. …”
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Anticancer Potential of Fruit Extracts from Vatica diospyroides Symington Type SS and Their Effect on Program Cell Death of Cervical Cancer Cell Lines by Atchara Chothiphirat, Kesara Nittayaboon, Kanyanatt Kanokwiroon, Theera Srisawat, Raphatphorn Navakanitworakul

“…MTT assay revealed that the extracts showed inhibition of cell survival in a dose-dependent manner and exhibited highly cytotoxic activity against both HeLa and SiHa cells with IC50 value less than 20 μg/mL along with less toxicity against L929 cells. …”
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The Stylistic and Generic Iconography in Selected Religious Epics with an Emphasis on Allusion by Zahra Faraj Nezhad Farhang

“…Some of these allusions which contain themes dealing with military tools and equipments and adverbs of manner and also paradox, have gained an epic format.  …”
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Adenosine-Induced NLRP11 in B Lymphoblasts Suppresses Human CD4+ T Helper Cell Responses by Irem Ozel, Ilgin Akkaya, Ece Oylumlu, Goksu Uzel, Ceren Ciraci

“…Taken together, our data indicate that adenosine is a negative regulator of Th1 and Th17 responses via NLRP11 in an inflammasome-independent manner.…”
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Exploring the potential effect and mechanisms of protocatechuic acid on human hair follicle melanocytes by Li Bo, Tan Jun, Zou Bosheng, Liu Xiaojia, Yu Yiling

“…In addition, the mRNA transcription and protein expression levels of TRP-1, TRP-2 and MITF significantly decreased with a dose-dependent manner after 24-hour PCA treated in HFM cells. Furthermore, PCA has significantly increased the SOD and GSH activity in a dose-dependent manner for 24-hour PCA treatment. …”
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Retsmedicinske findestedsundersøgelser by Peter Mygind Leth, Stine Hovvang, Asser Hedegård Thomsen

“…The goal was to determine the cause of death, the manner and mechanism of death, and the time of death. …”
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A Novel Energy-Efficient Reception Method Based on Random Network Coding in Cooperative Wireless Sensor Networks by Yulun Cheng, Longxiang Yang

“…In OR, the sensor nodes in intermediate cluster generate the independent coding vector through simple forwarding or decoding-recoding manners opportunistically, so that the number of received packets can be reduced. …”
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Inclusive mentorship of pediatric trainees: pediatric oncology as a microcosm by Sadhana Jackson, Sadhana Jackson, Jessica W. Tsai, Jessica W. Tsai, Kyle L. MacQuarrie, Kyle L. MacQuarrie

“…Mentoring consciously in an inclusive manner is a way to support all mentees, not just those who share identity with the mentor. …”
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Design and Kinematics Analysis of Wheel-leg Hybrid Robot with Four-legs by Zheng Hui, Wang Min, Wang Xinjie, Wang Caidong

“…According to the problem that the wheeled robots have poor ability to adapt terrain,and the legged robot moving speed is limited,a wheel-leg hybrid robot with four-legs is designed,which can both crawl and roll.And the robot is driven by steel wire rope with torsional spring scheme to realize switching function of working manner.In the overall design of the robot,the legs are detailed designed.The kinematic equation of standing leg is established by the D-H method,and the correctness of the kinematic equations is verified by Geometric method.The swinging leg motion space is obtained by MATLAB software.And the ability of the robot obstacle is analyzed.…”
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Imaginaires médiatiques de la résilience pastorale en Afrique subsaharienne by Étienne Damome, Nadège Soubiale

“…In the field of analysis of media content in ICS, this example provides an illustration of the manner in which the contents of the public and private press of West African countries reflect the contents of the sponsors’ speeches, which refer very explicitly to this paradigm.…”
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Upper Gastrointestinal Manifestation of Bezoars and the Etiological Factors: A Literature Review by Samiullah Khan, Kui Jiang, Lan-ping Zhu, Iftikhar-ahmad Khan, Kifayat Ullah, Saima Khan, Xin Chen, Bang-mao Wang

“…A gastric bezoar is a compact mass of indigestible foreign materials that accumulate and consolidate in the stomach; however, it can be found in other sites of the gastrointestinal tract. The causative manner of this condition is complex and multifactorial. …”
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Deux mois à la Légion : une autre vision de la forêt by François-Michel Le Tourneau

“…Besides describing the running of the course in the manner of a field book, I compare the teachings received on this occasion with others from other contexts, including with my experience among Native Americans. …”
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New Insights into Artesunate as a Pleiotropic Regulator of Innate and Adaptive Immune Cells by Lixian Lin, Zengqi Tang, Zhenrui Shi, Qing Guo, Hui Xiong

“…Of interest, emerging evidences suggest that artesunate also possesses an immunomodulatory effect during innate and adaptive immune responses in cell types and context-dependent manner. Although it shows promising application in many diseases, such as inflammatory diseases, hypersensitivity, autoimmune diseases, and cancers, little is known about underlying molecular. …”
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Inhibitory Effects of 4-(4-Methylbenzamino)benzoate on Adipocyte Differentiation by Jin Taek Hwang, Sanghee Kim, Bo-ra Yoon, Inwook Choi, Sang Yoon Choi

“…In addition, 4-(4-methylbenzamino)benzoate reduced the cellular expression of fatty acid synthase in a concentration-dependent manner, as well as suppressing PPAR-gamma activity, which controls fatty acid storage and glucose metabolism. …”
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Lectins from the Red Marine Algal Species Bryothamnion seaforthii and Bryothamnion triquetrum as Tools to Differentiate Human Colon Carcinoma Cells by Vicente P. T. Pinto, Henri Debray, Danuta Dus, Edson H. Teixeira, Taianá Maia de Oliveira, Victor Alves Carneiro, Alrieta H. Teixeira, Gerardo C. Filho, Celso S. Nagano, Kyria S. Nascimento, Alexandre H. Sampaio, Benildo S. Cavada

“…These lectins interacted with the cells tested in a dose-dependent manner. Moreover, the fluorescence spectra of both lectins clearly differentiated the cells used as shown by FACS profiles. …”
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