Flavins and Flavoproteins in the Neuroimmune Landscape of Stress Sensitization and Major Depressive Disorder by Schrier MS, Smirnova MI, Nemeth DP, Deth RC, Quan N

“…Besides the well-studied neurotransmission-related etiologies of MDD, several biological systems and phenomena, such as the hypothalamic-pituitary-adrenal (HPA) axis, reactive oxygen species (ROS) production, and cytokine signaling, have been implicated as being altered and contributing to depressive symptoms. However, the manner in which these factors interact with each other to induce their effects on MDD development has been less clear, but is beginning to be understood. …”
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The Role of Leadership, Religiousness and Work Environment in Supporting Employee Performance and How Motivation Affects The Relationship by Syafran Pardamean, Dodi Indrianto, Sekar Wulan

“…Originality/Value (State of The Art): This study highlights the importance of religiosity as a factor that has a positive impact on employee performance, especially if religious values are applied in a balanced and constructive manner. Leadership values driven by religiosity can improve employee performance and create a harmonious work environment. …”
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Lactoferrin Induces Osteoblast Growth through IGF-1R by Jian-Ming Hou, En-Yu Chen, Fan Lin, Qing-Ming Lin, Ying Xue, Xu-Hua Lan, Man Wu

“…Lactoferrin induced IGF-1/IGF-1R in a concentration-dependent manner. Lactoferrin promoted osteoblast proliferation while inhibiting apoptosis through IGF-1R. …”
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Syrian refugee and diaspora healthcare professionals: Case studies from the eastern mediterranean and European regions by Aula Abbara, Munzer Alkhalil, Kinan Wihba, Omer Abdrabbuh, Diana Rayes, Andrew Ghobrial, Manar Marzouk, Fadi Halabi, Mahmoud Hariri, Abdulkarim Ekzayez

“…Such policies that aim to invest in refugee HCPs’ skills, further develop their aptitudes, and potentially establish a connection between them and their homeland in a mutually beneficial manner for both health systems in exile and in their homeland. …”
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Interleukin-10 exhibit dose-dependent effects on macrophage phenotypes and cardiac remodeling after myocardial infarction by Jing J. Zhang, Rodrigue Rizk, Xiaoping Li, Brandon G. Lee, Mason L. Matthies, Kennedy A. Bietz, Kang Kim, Kang Kim, Kang Kim, Johnny Huard, Yadong Wang, William C. W. Chen

“…Moreover, different doses of IL-10 differentially modulated myocardial gene expression, phagocytic cell infiltration at the infarct, LV fibrosis, and revascularization post-MI, with some, but not all, doses exerting beneficial effects.DiscussionOur study suggested that IL-10 has an effective dose range on Mφ phenotypes, and intramyocardial IL-10 treatment may trigger cardioprotective or unwanted effects post-MI in a dose-dependent manner.…”
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Critical analysis of doctrinal approaches to the definition of “biological terrorism” by О. V. Shamsutdinov

“…Terrorism has been defined as socially dangerous criminal acts provided for by international and national law, which consist of demonstrative public violence in a generally dangerous manner or with particular cruelty, as well as threats, organisation, preparation, logistical, financial and other support or incitement to commit such acts aimed at intimidating the population, inducing specific institutions or individuals to commit or refuse to commit certain acts, or with the aim of destabilising or destroying law and order. …”
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The influence of e-trust on a job performance model based on employees’ dynamic capabilities during a crisis caused by a Black Swan event by Katarzyna Tworek, Guangyan Luo, Marcin Paska, Anna Sałamacha

“…The companies were selected on the basis of the purposive manner. The structured questionnaire was prepared and the CAWI (Computer-Assisted Web Interview) method was used in this research. …”
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Investigating the Relationships between Internet Addiction and Suicidal Ideation in Adolescent Girls by Zeynab Akbari, Fatemeh Serjouie, Jafar Sarani Yaztappeh, Mohammad Hossein Turkzadeh, Faeze Ziaei, Ali Bagheri, Maryam Sate Zohd, Amir Sam Kianimoghadam

“…Participants completed the Multidimensional Scale of Perceived Social Support (MSPSS), the Beck Scale for Suicidal Ideation (BSSI), the Cell-Phone Over-Use Scale (COS), the Youth Self-Report (YSR), and the Toronto Alexithymia Scale-20 (TAS-20) in a written manner. Data analysis was done using SPSS 25 and AMOS 22. …”
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Functional switching among dynamic neuronal hub-nodes in the brain induces maintenance/transition of cognitive states by Jasleen Gund, Yashaswee Mishra, B. N. Mallick, R. K. Brojen Singh

“…The switching behaviour in the ratio of hub/non-hub nodes between frontal and occipital regions during NREMS-Wake and Wake-NREMS transitions provides support as proof-of-principle of functional regional inactivation or activation of hub-nodes as the gradual switching mechanism towards transitioning of cognitive states in a graded (or non-flipping) manner, wake to sleep or vice versa; the detailed neuro-physio-chemical mechanism needs further study. …”
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Implementation of global health competencies: A scoping review on target audiences, levels, and pedagogy and assessment strategies. by Meike Schleiff, Bhakti Hansoti, Anike Akridge, Caroline Dolive, David Hausner, Anna Kalbarczyk, George Pariyo, Thomas C Quinn, Sharon Rudy, Sara Bennett

“…Further development is needed to understand how to assess competencies in a consistent and relevant manner.…”
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Ex vivo biotransformation of lady’s mantle extracts via the human gut microbiota: the formation of phenolic metabolites and their impact on human normal and colon cancer cell lines... by Katarzyna Jakimiuk, Aleksandra Kruk, Marta Kinga Lemieszek, Jakub W. Strawa, Sebastian Granica, Adrian Wiater, Michał Tomczyk

“…Samples from AVD1, AVD2, and AVD3 increase the lactate dehydrogenase (LDH) released from damaged colon cancer cells in a dose-dependent manner. At 250 μg/mL, AVD1, AVD2, and AVD3 elevated the LDH level by 12.6%, 25.3%, and 30.0%, respectively. …”
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An indole alkaloid from a tribal folklore inhibits immediate early event in HSV-2 infected cells with therapeutic efficacy in vaginally infected mice. by Paromita Bag, Durbadal Ojha, Hemanta Mukherjee, Umesh Chandra Halder, Supriya Mondal, Nidhi S Chandra, Suman Nandi, Ashoke Sharon, Mamta Chawla Sarkar, Sekhar Chakrabarti, Debprasad Chattopadhyay

“…The in vivo studies revealed that HM at its virucidal concentration was nontoxic and reduced virus yield in the brain of HSV-2 infected mice in a concentration dependent manner, compared to vaginal tissues. Thus, our results suggest that HM can serve as a prototype to develop non-nucleotide antiviral lead targeting the viral IE transcription for the management of HSV-2 infections.…”
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THE EFFECT OF ACTIVATING THE FOUNDATIONS OF SCENARIO THINKING IN INCREASING THE PERFORMANCE OF BUSINESS ORGANIZATIONS by Башир Гессаби, Муса Гессаби

“…There are not many organizations that are interested in analyzing the internal work system. economic and political variables directly and indirectly affect the strategic alternatives of organizations, which prompted many of them to develop alternative strategic options to confront these changes, by creating a set of possible scenarios in order to adapt in the face of obstacles and likely developments in the work environment in a more flexible and efficient manner. Nowadays the rapid changes in the environment and its complexities as a result of economic openness that business organizations in the household electrical industry have witnessed in the past decades have forced these organizations to operate in a highly competitive environment with local and international organizations having many years of experience in this fild, which in turn may expose them to numerous risks and lead to theif inbality to survive and continue their operations. …”
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Presenting the Model of Effective Factors on Smart Governance in the Country by Ghaem Gheiravani, Mohammad Montazeri, Shams Sadat Zahedi

“…The sampling method in this section was done in a random stratified manner. A semi-structured interview and a researcher-made questionnaire taken from the qualitative section were used to collect information. …”
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Propofol Regulates ER Stress to Inhibit Tumour Growth and Sensitize Osteosarcoma to Doxorubicin by Hua Wei, Xinhui Du, Huaping Zhao, Peipei Sun, Jianjun Yang

“…Propofol treatment led to significant growth inhibition in MG63 and 143B cells in a dose-dependent manner (p<0.05). Osteosarcoma migration (MG63 91.4 (82–102) vs. 56.8 (49–65), p<0.05; 143B 96.6 (77–104) vs. 45.4 (28–54), p<0.05) and invasion (MG63 68.6 (61–80) vs. 32 (25–39), p<0.05; 143B 90.6 (72–100) vs. 39.2 (26–55), p<0.05) were reduced after propofol treatment. …”
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Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis by Lei Xiang, Qingzhou Li, Zhiwei Guan, Guilin Wang, Xiankuo Yu, Xianwen Zhang, Guochen Zhang, Jushan Hu, Xue Yang, Mingrui Li, Xilinqiqige Bao, Yumei Wang, Dong Wang

“…The MOA was explored using L1000, Drug Gene DataBase (DGDB), and Western blotting analyses.ResultsORes significantly reduces breast cancer cell viability and proliferation in a concentration-dependent manner, with IC50 values of 104.8 μM, 150.2 μM, and 143.6 μM in MDA-MB-231, BT-549, and 4T1 cells, respectively. …”
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Shared genetics between breast cancer and predisposing diseases identifies novel breast cancer treatment candidates by Panagiotis N. Lalagkas, Rachel D. Melamed

“…Similarly, for all drugs treating the predisposing disease, we link their targets to pathways. In this manner, we are able to prioritize a list of drugs based on each predisposing disease, with each drug linked to a set of implicating pathways. …”
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Osmanlı Öncesi İpekçiliğe Dair İzler ve Osmanlı Dönemi Edirne İpekçiliği by Hüsnü YÜCEKAYA

“…The second aspect of the issue is that the silk farming culture was put into practice in a very rapid manner all over the Ottoman lands. A preliminary phase that requires centuries was realized in a very rapid fashion. …”
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Methane Extraction and Resource Utilization Based on Multisource Data Fusion by Wensheng Chen, Zhongliang Lu

“…For this consideration, supported by the surface assimilation figure of qualifier-enclose char, the magnificent orthodox whole Monte Carlo (GCMC) manner was interesting to ponder the elution conduct of CH4 in the wind-confine charcoal configuration after the farding bag of N2/CO2 under distinct enema stamp. …”
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Throughout Maximization for IRS-Assisted WPCN With Hybrid TDMA-NOMA Scheme by Yizheng Ma, Ruoyi Wu, Yi Zhang, Yupeng Shang, Linzhen Zhu

“…These devices firstly collect energy in a non-linear manner disseminated by a power station (PS) at downlink wireless energy transfer (WET) stage. …”
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