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3521
Multi-Temporal Analysis and Techno-Economic Evaluation of Offshore Wind Energy Integration to the Western Interconnection
Published 2024-01-01“…Through an iterative manner, the proposed approach identifies necessary upgrades to the transmission system based on PF results, builds the upgrades in the PCM, and re-runs. …”
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3522
Effect of probiotic-fermented milk containing Lactiplantibacillus pentoses strain HBUAS 53657 on serum glutathione peroxidase activity and pancreatic histopathology in hyperglycemi...
Published 2024-12-01“…PFM also increased the Langerhans islet area (p = 0.001) and reduced islet damage scores (p < 0.001) in a dose-dependent manner. Conclusion: Probiotic-fermented milk containing Lactiplantibacillus pentosus strain HBUAS 53657 increases serum GPx activity, expands Langerhans islet area, and reduces islet damage in hyperglycemic rats. …”
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3523
Relationship between Neovascular Density in Swept Source-Optical Coherence Tomography Angiography and Signs of Activity in Exudative Age-Related Macular Degeneration
Published 2019-01-01“…To assess the relationship between signs of activity in exudative neovascular age-related macular degeneration (nAMD) following anti-vascular endothelial growth factor (anti-VEGF) treatment and morphology of choroidal neovascularization (CNV) based on neovascular density as imaged using swept source-optical coherence tomography angiography (SS-OCTA) in a qualitative manner. Methods. A single-cohort retrospective data analysis from one tertiary eye care center. …”
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3524
Tire rubber-derived contaminants 6PPD and 6PPD-quinone reduce attachment and outgrowth of trophoblast spheroids onto endometrial epithelial cells
Published 2025-01-01“…Treatment with the chemicals for up to 48 h decreased the viability of the cells in a dose- and cell line-dependent manner (20–100 μM 6PPD and 10–100 μM 6PPDQ for both the cell lines). …”
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3525
A patient-led survey on information and communication needs of patients with metastatic breast cancer in Ireland and Northern Ireland (CTRIAL-IE 23–05)
Published 2025-02-01“…Most patients were satisfied with the manner of disclosure of their diagnosis but 77 % wanted more prognostic information. …”
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3526
Resistance of Biomphalaria alexandrina to Schistosoma mansoni and Bulinus truncatus to Schistosoma haematobium Correlates with Unsaturated Fatty Acid Levels in the Snail Soft Tissu...
Published 2020-01-01“…Diet manipulation directed to eliciting excessive increase of polyunsaturated fatty acids in snails may protect them from infection and interrupt disease transmission in a simple and effective manner.…”
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3527
An Empirical Study of Visitors’ Experience at Kuching Orchid Garden with Mobile Guide Application
Published 2018-01-01“…A limitation was providing relevant information in a timely and seamless manner due to inaccuracies of mapping between physical and digital environments. …”
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3528
Demethylnobiletin and its major metabolites: Efficient preparation and mechanism of their anti-proliferation activity in HepG2 cells
Published 2022-09-01“…The results showed that all 4 compounds inhibited the proliferation of HepG2 cells in a concentration-dependent manner. Their anti-proliferative activity was exerted through inducing G2/M phase arrestment, cell apoptosis and promoting expression of a key apoptotic protein called cleaved caspase-3. …”
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3529
Development, optimization and application of a universal fluorescence multiplex PCR-based assay to detect BCOR genetic alterations in pediatric tumors
Published 2025-01-01“…Methods that analyze these variants simultaneously in a sensitive and convenient manner are lacking in clinical practice. Methods This study validated a Universal Fluorescence Multiplex PCR-based assay that assessed BCOR ITDs, BCOR::CCNB3, BCOR::MAML3 and YWHAE::NUTM2 fusions simultaneously. …”
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3530
Complementary medicine in orthopaedic and trauma surgery: a cross-sectional survey on usage and needs
Published 2020-09-01“…They wish to be treated in a holistic manner and want to strengthen self-efficacy.Conclusions Usage of CAM of patients in orthopaedic and trauma surgery appears to be high. …”
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3531
SKF96365 Inhibits Tumor Proliferation by Inducing Apoptosis and Autophagy in Human Esophageal Squamous Cell Carcinoma
Published 2024-01-01“…SKF96365 induces apoptosis in three cell lines through the poly(adenosine diphosphate–ribose) polymerase (PARP), caspase-9, and BCL-2 pathways in a dose-dependent and time-dependent manner. Moreover, SKF96365 treatment also induced apoptosis and inhibited tumor growth in nude mice. …”
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3532
Antiviral Activity of Pistacia atlantica subsp. Kurdica Extract Against Herpes Simplex Virus Type 1
Published 2024-07-01“…Kurdica had an anti-HSV1 effect in a dose-dependent manner but at a higher dose than acyclovir. Ethanolic extract of P. atlantica subsp. …”
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3533
Experimental and Numerical Investigation on Seismic Performance of RC Exterior Beam-Column Joints with Slabs
Published 2022-01-01“…Consequently, the contribution of slab to the seismic resistance of structures is often ignored or just included in an approximate manner. In this study, the experiment of two 1/2-scaled exterior beam-column joints without slabs and three 1/2-scaled joints with slabs under the combination of quasi-static repeated cyclic loading and constant axial force was carried out to investigate the effect of the cast-in-place slab on the seismic performance of exterior beam-column joints. …”
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3534
Depth Penetration and Scope Extension of Failures in the Cascading of Multilayer Networks
Published 2020-01-01“…Real-world complex systems always interact with each other, which causes these systems to collapse in an avalanche or cascading manner in the case of random failures or malicious attacks. …”
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3535
THE "PACKAGE" OF HUNTING IN LA PAMPA AND ITS TERRITORIAL IMPLICATIONS
Published 2018-12-01“…The research indicates that the provincial government has intervened actively and in a sustained manner from different agencies over time. These elements were generating a territorial imaginary around hunting with different intentions according to the programs and institutions that promoted it. …”
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3536
Mapping Nanoscale‐To‐Single‐Cell Phosphoproteomic Landscape by Chip‐DIA
Published 2025-01-01“…The iPhosChip operates as an all‐in‐one station that accommodates both quantifiable cell capture/imaging and the entire phosphoproteomic workflow in a highly streamlined and multiplexed manner. Coupled with a sample size‐comparable library‐based DIA‐MS strategy, Chip‐DIA achieved ultra‐high sensitivity, detecting 1076±158 to 15869±1898 phosphopeptides from 10±0 to 1013±4 cells, and revealed the first single‐cell phosphoproteomic landscape comprising druggable sites and basal phosphorylation‐mediated networks in lung cancer. …”
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3537
Activation of the periaqueductal gray controls respiratory output through a distributed brain network
Published 2025-01-01“…We then stimulated PAG terminals in those regions to determine whether their activity can account for the observed effects of PAG stimulation.ResultsDirectly stimulating the PAG resulted in prominent changes to all recorded muscle activities and reset the breathing rhythm in either a phase-independent or phase-dependent manner. In contrast, stimulating PAG terminals in either preBötC or pFL with long or shorter timescale stimuli could not completely replicate the effects of direct PAG stimulation and also did not produce any respiratory reset.ConclusionsOur results show that the effects of PAG activity on respiration are not mediated solely by PAG inputs to either the preBötC or pFL and more likely involve integration across a larger network of brainstem areas.…”
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3538
Bexarotene-induced hypothyroidism and dyslipidemia; a nation-wide study
Published 2024-08-01“…Triglycerides (TG) increased in a bexarotene dose–dependent manner, and grade ≥3 AEs on hypertriglyceridemia was observed in 39% of the patients. …”
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3539
Investigation of newborn blood metabolomics in varying intrauterine growth conditions
Published 2025-01-01“…Conclusion: Continuous monitoring of the short-term and long-term growth and metabolic status of full-term SGA and LGA newborns is warranted with individualized dietary and nutritional adjustments to promote healthy growth in a timely manner. The findings of this research contribute to the broader understanding of SGA/LGA and shall inform future research on metabolomics, interventions, and long-term outcomes.…”
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3540
Monascus red pigment influence on hydroxyapatite nanoparticles-mediated renal toxicity in rats
Published 2025-01-01“…This was confirmed by pronounced improvement in the measured parameters along with the histological structural enhancement in a dose dependent manner compared to controls. To sum up, RP from M. purpureus has potential protective benefits in mitigating the adverse effects of HANPs.…”
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