A study on the carbon emission reduction pathways of China’s digital economy from multiple perspectives by Xiaoyan Shi, Zhenhua Zhu, Jiaxin Wu, Zhijiang Li

“…Under the influence of urbanization, there is an inverted U-shaped relationship between DE and CE. (4) Heterogeneity analysis finds that, compared to other types of provinces, the CER effect of DE is stronger in non-resource-based and economically developed provinces. (5) We propose five tailored recommendations for CER: fostering the synergistic development of the DE and industrial structure, strengthening the role of technological innovation, advancing urbanization and carbon reduction in a differentiated manner, formulating distinct policies for resource-based and non-resource-based provinces, and enhancing the construction of digital infrastructure in less-developed regions. …”
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A microbiota-derived metabolite, 3-phenyllactic acid, prolongs healthspan by enhancing mitochondrial function and stress resilience via SKN-1/ATFS-1 in C. elegans by Juewon Kim, Yunju Jo, Gyumin Lim, Yosep Ji, Jong-Hwa Roh, Wan-Gi Kim, Hyon-Seung Yi, Dong Wook Choi, Donghyun Cho, Dongryeol Ryu

“…Our findings reveal that PLA treatment significantly extends the healthspan of C. elegans by promoting energy metabolism and stress resilience in a SKN-1/ATFS-1-dependent manner. Moreover, PLA-mediated longevity is associated with a novel age-related parameter, the Healthy Aging Index (HAI), introduced in this study, which comprises healthspan-related factors such as motility, oxygen consumption rate (OCR), and ATP levels. …”
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Spiking Neural Networks for Energy-Efficient Acoustic Emission-Based Monitoring by Federica Zonzini, Wenliang Xiang, Luca de Marchi

“…Furthermore, the event-driven capabilities of neuromorphic architectures (and spiking neural networks (SNNs) in particular) in processing spiky and sparse temporal information are exploited to retrieve ToA in a beyond state-of-the-art power-efficient manner and negligible loss of performance with respect to standard models. …”
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TEX10 Promotes the Tumorigenesis and Radiotherapy Resistance of Urinary Bladder Carcinoma by Stabilizing XRCC6 by Sheng Luo, Wenjin Wang, Jingfang Feng, Rui Li

“…Results showed that TEX10 is abundant in urinary bladder carcinoma, and its protein level was related to poor disease-free survival in a positive manner. Reduced TEX10 level inhibited urinary bladder carcinoma cell proliferating process and metastasis in vitro and xenograft tumorigenicity in vivo. …”
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Mini meta-analysis of anticholinesterase actions of atorvastatin, simvastatin and rosuvastatin, and in silico identification of their protein targets in Mus musculus by Fouad Kasim Mohammad, Rawnaq Faris Al-Shalchi

“…The findings highlight statin effects in mice by reducing blood and brain ChE activities, in a dose/concentration-dependent manner, that would potentially modulate the cholinergic system. …”
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Anti-Idiotypic Antibody as a Booster Vaccine Against Respiratory Syncytial Virus by Shreya Mukhopadhyay, Ioannis Manolaridis, Christopher Warren, Aimin Tang, Gregory O’Donnell, Bin Luo, Ryan P. Staupe, Kalpit A. Vora, Zhifeng Chen

“…One potential approach involves using anti-idiotypic antibodies (anti-IDs) to mimic specific antigenic sites and enhance preexisting immunity in an epitope-specific manner. RB1, a monoclonal antibody (mAb) that binds to site IV of the RSV fusion (RSV F) protein, is a potent and broadly neutralizing against RSV A and B viruses. …”
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Multi-dimensional performance-based intelligent optimization of atrium building prototype with informed approach by Yiquan Zou, Yanyan Li, Han Chen, Benlin Xiao, Zhou Li

“…Ultimately, architects were provided with prototype forms of the atrium space in an "Informed" manner, which expedited the architectural design process. …”
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A new approach for detecting HPV DNA in cervical swabs: comparison of nucleic acid extraction with direct PCR by Fatih Çubuk, Muhammet Çağrı Yıldız, Fikrican Balcı, Ahmet İrgin, Savaş Aşkın, Ekrem Sağtaş, Sedat kaygusuz

“…Cervical cancer screening programs require the ability to process a large number of samples in a simple and standardized manner and obtain reliable results. The workload, time, and cost associated with the number of samples to be processed encourage the development of alternative methods to the traditional nucleic acid extraction method for population-based screening. …”
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Establishment of Early Multi-Indicator Prediction Models of Moderately Severe Acute Pancreatitis and Severe Acute Pancreatitis by Shan-Shan He, Dan Li, Qi-Yong He, Xiao-Ping Chen, Yong-Xu Lin, Yun-Wen Yu, Feng-Lin Chen, Jian Ding

“…It is critical to accurately identify patients with severe acute pancreatitis (SAP) and moderately SAP (MSAP) in a timely manner. The study was done to establish two early multi-indicator prediction models of MSAP and SAP. …”
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1-Bromopropane induces mitochondrial damage and lipid metabolism imbalance in respiratory epithelial cells through the PGC-1α/PPARα pathway by Qiuyun Wu, Chunmeng Jin, Xue Liu, Qianyi Zhang, Biyang Jiao, Hongmin Yu

“…We found that exposure to 1-BP markedly reduced the viability of respiratory epithelial cells in a dose-dependent manner, and induced oxidative stress and vacuolation changes in respiratory epithelial cells. …”
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Impact of Gender on the Association of Epicardial Fat Thickness, Obesity, and Circadian Blood Pressure Pattern in Hypertensive Patients by In Kyoung Shim, Kyoung-Im Cho, Hyun-Su Kim, Jung-Ho Heo, Tae Joon Cha

“…The relationships among circadian BP variability, obesity, and EFT were affected by gender in different manners. EFT may be a more valuable parameter in the evaluation of BP severity and obesity in women than in men.…”
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Decreased S100A9 Expression Promoted Rat Airway Smooth Muscle Cell Proliferation by Stimulating ROS Generation and Inhibiting p38 MAPK by Lei-Miao Yin, Xiao-Jie Han, Ting-Ting Duan, Yu-Dong Xu, Yu Wang, Luis Ulloa, Yong-Qing Yang

“…Our previous study showed that S100A9 (S100 calcium-binding protein A9; 400 and 800 ng/mL) significantly inhibited rat ASMCs proliferation at 48 h, and 50–800 ng/mL S100A9 (50, 100, 200, 400, and 800 ng/mL) also induced a lasting effect by significantly inhibiting rat ASMCs proliferation at 72 h in a dose-dependent manner. However, the intracellular effects of S100A9 on ASMCs proliferation remain unknown. …”
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A cost‐effective video system for a rapid appraisal of deep‐sea benthic habitats: The Azor drift‐cam by Carlos Dominguez‐Carrió, Jorge Fontes, Telmo Morato

“…Rather, it aims to provide the means to perform quick assessments of deep‐sea benthic habitats in a simple and affordable manner. This drift‐cam system has the potential to make deep‐sea exploration more accessible, playing an important role in the Deep‐Ocean Observing Strategy and measuring some of the Essential Ocean Variables for deep‐sea monitoring and conservation strategies.…”
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Polysaccharide Fraction Isolated from <i>Saccharina japonica</i> Exhibits Anti-Cancer Effects Through Immunostimulating Activities by Min Seung Park, Seung-U Son, Tae Eun Kim, Se Hyun Shim, Bong-Keun Jang, Sunyoung Park, Kwang-Soon Shin

“…The release of immune-activating cytokines, including IL-6, IL-12, and TNF-α, was markedly stimulated by the SJP in a concentration-dependent manner within the range of 1 to 100 µg/mL. Furthermore, the prophylactic intravenous (<i>p.i.v.…”
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Out-of-distribution generalization for segmentation of lymph node metastasis in breast cancer by Yiannis Varnava, Kiran Jakate, Richard Garnett, Dimitrios Androutsos, Pascal N. Tyrrell, April Khademi

“…This work proposes a novel clustering and sampling method to automatically curate training datasets in an unsupervised manner with the aim of improving model generalization abilities. …”
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Interpretive structural modeling of factors affecting the internal development of cities in arid regions (Case study: Ardakan city by mohamad reza hatafi ardakani, mphammad hosein saraei, mohamad mahdi karimnejad, seyed ali almodaresi, saideh moayed far

“…In order to achieve the research objectives, using a new analytical methodology of interpretive structural modeling (ISM), the relationships between the factors were determined and analyzed in an integrated manner. Finally, using MICMAC analysis, the factors were analyzed according to the impact and effectiveness on other components. …”
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Manhaj Ithbat Salaf Scholars in Interacting with Characteristics of Khabariyyah According To The Explanation Of Imam Abu Al-Hasan Al-Ash`Ari by Mohd Saiba Yaacob, Syed Hadzrullathfi Syed Omar, Engku Ibrahim Engku Wok Zin

“…One of its main features is that it teaches the Sifat Khabariyyah's external meaning as worthy of Allah SWT by rejecting the existence of kayfiyyat (form, appearance, characteristics, and manner), without interpretation, without ta'wil (representation), without tamthil (equalisation), without tashbih (simulation), and denying the Sifat al-huduth (new attributes) like location, mass, movement, and displacement. …”
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Key health impacts and support systems for informal carers in the UK: A thematic review by Susanna A Cottagiri, Peter Sykes

“…Financial help, proper respite care, availability and accessibility of information and advice, provision of equipment in a timely manner and adequate support networks were found to be key factors useful in minimising musculoskeletal and psychological disorders. …”
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Attribution of a record-breaking cold event in the historically warmest year of 2023 and assessing future risks by Yangbo Ye, Cheng Qian, Aiguo Dai, Yuting Zhang, Jiacheng Jiang, Xiaoye Zhang

“…Abstract An unexpected record-breaking cold event struck eastern China in December 2023, causing widespread transportation shutdowns, power supply shortages, and agricultural crop damage. The manner in which such an extraordinary cold event was formed under global warming is unclear, as is the way in which anthropogenic climate change may affect the present and future frequency and intensity of similar cold events. …”
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Pyrroloquinoline Quinone Administration Alleviates Allergic Airway Inflammation in Mice by Regulating the JAK-STAT Signaling Pathway by Zhihui Min, Jiebai Zhou, Ruolin Mao, Bo Cui, Yunfeng Cheng, Zhihong Chen

“…Pretreatment with PQQ significantly decreased HDM-stimulated thymic stromal lymphopoietin (TSLP) production in a dose-dependent manner in 16-HBE cells and inhibited Th2 cell differentiation in vitro. …”
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