Effect of Interferon-γ on the Basal and the TNFα-Stimulated Secretion of CXCL8 in Thyroid Cancer Cell Lines Bearing Either the RET/PTC Rearrangement Or the BRAF V600e Mutation by Mario Rotondi, Francesca Coperchini, Oriana Awwad, Patrizia Pignatti, Christian A. Di Buduo, Vittorio Abbonante, Flavia Magri, Alessandra Balduini, Luca Chiovato

“…IFNγ inhibited in a dose-dependent and significant manner both the basal (ANOVA F: 22.759; p<0.00001) and the TNFα-stimulated (ANOVA F: 15.309; p<0.00001) CXCL8 secretions in BCPAP but not in TPC-1 cells (NS). …”
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Cultural Dyphemisms in the Turkish Culture Region by İlhami Durmuş

“…Thus the life continued in a manner of searching new pastures and shuttling between plateau and winter quarters . …”
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Perception of Professional Practices from the voice of the student body of Pedagogy by Rosario Ordóñez-Sierra, Mª Teresa Gómez-del-Castillo-Segurado, Margarita Rodríguez-Gallego

“… This study highlights the importance of the practicum in the training of education professionals, since it is a key moment for students to reach the specific competences of the profession in an active and reflective manner. The main aim of research in this field is to assess the pedagogy students’ perception of the blog, videoconference, and peer mentoring as effective tools for reflection and communication in monitoring and evaluating professional practices. …”
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Levistolide A and periplogenin inhibit the growth of gastric cancer cells in vitro and in vivo by Jia Li Guo, Hong Mei Hu, Shao Chin Lee, Ji Zhong Zhao

“…Results: The results in the present study shown that the two compounds were able to inhibit the viability of the cancer cells in a dose- and time-dependent manner by MTT method. They could trigger apoptosis when used alone, and more potently, in combination with 5-FU detected by TUNEL positivity and the cleavage of caspase substrate PARP. …”
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Exploring RNA-Seq Data Analysis Through Visualization Techniques and Tools: A Systematic Review of Opportunities and Limitations for Clinical Applications by Farhana Manzoor, Cyruss A. Tsurgeon, Vibhuti Gupta

“…RNA sequencing (RNA-seq) has emerged as a prominent resource for transcriptomic analysis due to its ability to measure gene expression in a highly sensitive and accurate manner. With the increasing availability of RNA-seq data analysis from clinical studies and patient samples, the development of effective visualization tools for RNA-seq analysis has become increasingly important to help clinicians and biomedical researchers better understand the complex patterns of gene expression associated with health and disease. …”
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Characterization of LY3324954 a long-acting glucagon-receptor agonist by William Roell, Tamer Coskun, Teayoun Kim, Libbey O’Farrell, Jennifer A. Martin, Shelly Nason, Jasmin Hernandez-Alamillo, Saidharshana Dhantu, Daniel J. Drucker, Kyle W. Sloop, James P. Steele, Jorge Alsina-Fernandez, Kirk M. Habegger

“…In diet-induced obese mice, LY3324954 treatment stimulates energy expenditure, weight loss, and a reduction of adiposity in a dose-dependent manner. Benefit to whole-body lipid homeostasis was likewise observed in these mice. …”
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Experimental Investigation of Chemical Flooding Using Nanoparticles and Polymer on Displacement of Crude Oil for Enhanced Oil Recovery by Imran Akbar, Hongtao Zhou, Wei Liu, Muhammad Usman Tahir, Asadullah Memon, Ubedullah Ansari, Fengzhang Lv

“…Some reservoirs are very complex and require advanced enhanced oil recovery (EOR) techniques containing new materials and additives in order to produce maximum oil in economic and environmental friendly manners. In this work, the effects of nanosuspensions (KY-200) and polymer gel HPAM (854) on oil recovery and water cut were studied in the view of EOR techniques and their results were compared. …”
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A decentralized optimization framework for multi-MGs in distribution network considering parallel architecture by Dengyin Jiang, Xiaoqian Zhou, Qian Ai, Yuanjun Hou, Yuan Zhao

“…Accelerated ATC algorithm can be applied to perform decentralized optimization in a sequential manner between distribution network agents and microgrid agents in a faster convergence speed compared with the traditional ATC algorithm. …”
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Scalable and Privacy-Preserving Inter-AS Routing Through Machine-Learning-Based Graph Pruning by Davide Andreoletti, Cristina Rottondi, Silvia Giordano, Andrea Bianco

“…., a common policy in routing tasks) in a privacy-preserving manner have been proposed. These protocols are based on Multi-Party Computation (MPC) schemes, which guarantee privacy at the cost of high computational and communication complexity, thus limiting scalability. …”
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Development of a Multifunctional Chitosan-Based Composite Film from Crab Shell (<i>Portunus segnis</i>) and Algae (<i>Ulva lactuca</i>) with Enhanced Antioxidant and Antimicrobial... by Imen Zaghbib, Johar Amin Ahmed Abdullah, Alberto Romero

“…The antioxidant activity improved in a concentration-dependent manner, as evidenced by the high free-radical scavenging capacity. …”
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Spatially ordered recruitment of fast muscles in accordance with movement strengths in larval zebrafish by Sayaka Shimizu, Taisei Katayama, Nozomi Nishiumi, Masashi Tanimoto, Yukiko Kimura, Shin-ichi Higashijima

“…As the speed or strength of the movements increases, more fast muscle cells are recruited in a spatially-ordered manner, progressively from lateral to medial. We also conducted anatomical studies to examine muscle fiber size. …”
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True cancer stem cells exhibit relative degrees of dormancy and genomic stability by Sanford H. Barsky, Krista Mcphail, Justin Wang, Jordan Dillard, Crystal J. Beard, Yin Ye

“…However, even if these properties can be demonstrated within a tumor cell subpopulation, it does not mean that they are truly hierarchical stem cells because they could have been derived from the proliferating population in a reversible manner. Methods: Using a human PDX, Mary-X, that overall expressed a strong cancer stem cell phenotype, the study conducted both GPP-labelled retroviral transfection and fluorescent microsphere uptake studies to distinguish proliferating from dormant cells and array CGH to identify regions of amplifications (gains) and deletions (losses) on the overall Mary-X population and then applied derived probes by FISH on individual cells to identify a genomically stable subpopulation. …”
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Variant of Organizational and Functional Adaptation Structures of a Typical Situational Centre to the Emergence of Crisis Situations by Volodymyr Mirnenko, Oleh Hudyma, Vadym Artamoshchenko

“…The article highlights the organization of information interaction between state structures during full-scale conflicts, the ways of resolving the SC in such conditions and the measures taken to respond effectively in a timely manner. Particular attention is paid to approaches to information counteraction in crisis management. …”
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The phenomenon of dormant inheritance in inheritance law by O. Ye. Kukhariev

“…It is emphasized that a necessary condition for the emergence of the right of ownership of the inheritance is its acceptance by the heir in the manner and terms determined by civil legislation. …”
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Approaching maximum resolution in structured illumination microscopy via accurate noise modeling by Ayush Saurabh, Peter T. Brown, J. Shepard Bryan IV, Zachary R. Fox, Rory Kruithoff, Cristopher Thompson, Comert Kural, Douglas P. Shepherd, Steve Pressé

“…Consequently, achieving high contrast near the maximum theoretical resolution in an unsupervised, physically principled manner remains an open problem. Here, we propose Bayesian-SIM (B-SIM), a Bayesian framework to quantitatively reconstruct SIM data, rectifying these shortcomings by accurately incorporating known noise sources in the spatial domain. …”
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Original Personalized Reconstruction Method for Certain Large Tumors of the Lower Lip (Not Including Oral Commissures) by Ovidiu Dan Grigorescu, Marius Irimie, Nadinne Roman, Roxana Steliana Miclaus, Maria-Cristina Cîmpeanu, Bogdan-Radu Necula, Christian-Gabriel Strempel, Simona Grigorescu, Marius Alexandru Moga, Dana Gabriela Festila

“…<i>Results</i>: Applied in a personalized manner, impressive results were obtained in several patients with lip tumors affecting about one-half of the lower lip length and in whom oncological surgical ablation produced defects in more than two-thirds of it. …”
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Empirical evidence for a process-based model of health-related quality of life using network analysis by Nicolette Stogios, Nicolette Stogios, Troy Francis, Troy Francis, Rachel G. Peiris, Aleksandra Stanimirovic, Aleksandra Stanimirovic, Valeria Rac, Valeria Rac, Robert P. Nolan, Robert P. Nolan

“…In support of this approach, we developed a novel HRQL assessment tool called the EUROIA: EvalUation of goal-diRected activities to prOmote wellbeIng and heAlth, which uses self-report data to assess the frequency with which individuals engage in a sample of goal-directed activities in pursuit of living well.MethodsWe conducted a network analysis to evaluate the hypothesis that the EUROIA subscales would demonstrate a meaningful pattern of associations with an established HRQL measure and associated indices of psychosocial functioning and efficacy in self-managing a chronic medical condition.ResultsThe EUROIA is associated with established indices of HRQL in a manner that is theoretically consistent with our process-based model. …”
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Factors affecting patient satisfaction during endoscopic procedures by Maryam Ghazala, E-Hinna Rashk, Sardar Saman, Khan Jahangir, Isram Javaria, Hassan Fayyaz

“…Additionally, the personal manner of the physician and nurses, as well as comprehensive explanations before and after the procedure, were also significant factors. …”
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Modulatory effects of rutin on the expression of cytochrome P450s and antioxidant enzymes in human hepatoma cells by Karakurt Sedar

“…Rutin inhibited proliferation of HEPG2 cells in a dose-dependent manner with the IC50 value of 52.7 μmol L-1 and invasion of HEPG2 cells (21.6 %, p = 0.0018) and colony formation of those invaded cells (57.4 %, p < 0.0001). …”
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Differentiation of Rat Adipose-Derived Stem Cells into Parathyroid-Like Cells by Ping Zhang, Hao Zhang, Wenwu Dong, Zhihong Wang, Yuan Qin, Changhao Wu, Qi Dong

“…SHH and activin A stimulated parathyroid hormone secretion by the adipose-derived stem cells and significantly increased the expression of calcium-sensing receptor (CaSR), parathyroid hormone, and glial cells missing homolog 2 (GCM2) in the cells in a time- and concentration-dependent manner. Conclusion. We successfully differentiated rat adipose-derived stem cells into parathyroid-like cells, which will pave a new route to curing hypoparathyroidism.…”
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