Notch1 Signaling Regulates the Th17/Treg Immune Imbalance in Patients with Psoriasis Vulgaris by Lei Ma, HaiBo Xue, Tianqin Gao, MeiLan Gao, YuJie Zhang

“…DAPT treatment resulted in the obvious downregulation of Th17 cell percentage in cocultured CD4+ T cells, RORγt and IL-17 mRNA levels, and IL-17 concentration in cell-free supernatant from cocultured CD4+ T cells of PV patients in a dose-dependent manner, while there was no significant influence on Treg cell percentage, Foxp3, and IL-10 expression, therefore leading to the recovery of Th17/Treg immune imbalance. …”
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Quantum algorithms for enhanced educational technologies by Basil Hanafi, Mohammad Ali, Devyaani Singh

“…This is a novel approach, applying quantum algorithms to enhance educational technologies, with no previous studies addressing the integration of quantum computing for personalized learning, data security, and resource optimization in such a comprehensive manner. It is in this context that the present paper delves into the role of quantum algorithms in education ecosystems and focuses on their capacity for transforming both learner and institution personalization, resources management, and secure data protection in learning contexts. …”
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Phenolic Compounds from Water-Ethanol Extracts of Tetrapleura tetraptera Produced in Cameroon, as Potential Protectors against In Vivo CCl4-Induced Liver Injuries by Peter William Kemewele Saague, Bruno Moukette Moukette, Jacques Romain Njimou, Prosper Cabral Nya Biapa, Francine Nzufo Tankeu, Vicky Joseline Ama Moor, Constant Anatole Pieme, Jeanne Yonkeu Ngogang

“…In rats treated with the extract of T. tetraptera, in a dose-dependent manner, the levels of hepatotoxicity markers such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) significantly increased while the enzyme activities of superoxide dismutase (SOD), catalase (CAT), and the level of reduced glutathione (GHS) significantly increased compared to the control group. …”
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La Inserción internacional de Suramérica: la apuesta por la Unasur by Carlos Alberto Chaves García

“…The creation and launch of the Union of South American Nations (Unasur) is the most recent institutional expression of this new attempt at the integration of South American countries, which seeks to articulate the distinct regional agendas proposed by the region’s governments in recent years. In like manner, the new experience of regional cohesion responds to the projection of the geostrategic interests of Argentina, Brazil, and Venezuela, as an expression of the competence of the leadership of said scheme for regional cooperation and integration.…”
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Resveratrol, Acetyl-Resveratrol, and Polydatin Exhibit Antigrowth Activity against 3D Cell Aggregates of the SKOV-3 and OVCAR-8 Ovarian Cancer Cell Lines by Simon J. Hogg, Kenny Chitcholtan, Wafaa Hassan, Peter H. Sykes, Ashley Garrill

“…Results showed that resveratrol and acetyl-resveratrol reduced cell growth in the SKOV-3 and OVCAR-8 in a dose-dependant manner. The growth reduction was mediated by the induction of apoptosis via the cleavage of poly(ADP-ribose) polymerase (PARP-1). …”
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Measurement and identification of areas susceptible to flood spreading from the viewpoint of geological formations in Birjand watershed using RS / GIS by Parviz Ziaiian Firouz Abadi, Ayoub Badragh Nejad, Reza Sarli, Mahboub Babaie

“…The results of the study showed that the areas that the effort for exploiting floods was made have characteristics such as (existence of alluvium and colluvium sediments in the high steep feet of the slopes and watersheds with major stone occurrences, existence of fan-shaped sediments and alluvial fan in the external aperture of dry rivers and water ways with mountainous watersheds and hills leading to low steep fields, existence of low fields from the manner of altitude in proportionate to fields near). …”
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Evaluating translational science knowledge gains following an online short course for a general scientific audience by Amanda L. Vogel, Shadab F. Hussain, Jessica M. Faupel-Badger

“…Delivering this content in a highly accessible manner will help expand and diversify the workforce. …”
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Effects of Adding Clove (Syzygium aromaticum L.)  Seed Extract on Oxidative Stability, Microbial Activity, and Sensory Attributes in Beef Patties During Refrigerated Storage by Bestoon Hassan Ahmed, Naska Abdulqadir Mohammed Mohammed

“…Microbial growth was inhibited in a concentration-dependent manner; for instance, aerobic plate counts decreased from 5.31 to 4.68 Log10 colony forming unit (CFU)/g, and coliform counts declined from 2.92 to 2.57 Log10 CFU/g at 0.30% CSE. …”
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Multi-Task Learning for Alzheimer’s Disease Diagnosis and Mini-Mental State Examination Score Prediction by Jin Liu, Xu Tian, Hanhe Lin, Hong-Dong Li, Yi Pan

“…Therefore, it can be used as a reference for the clinical diagnosis of Alzheimer’s disease, and can also help doctors and patients track disease progression in a timely manner.…”
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Models of technological development: The influence of investment structure by Vilhelmina V. Glazunova, Oleg S. Sukharev

“…Then, accord ing to the impact of investment in new technologies on technological modernisation it justifies the models “blockage”, “rigidity”, “modernisation”, “saturation”, and, in a similar manner, validates the models “degradation”, “backwardness”, “reliance on old technologies”, “reliance on new technologies” according to the impact of investment in old technologies on technological modernisation. …”
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ARRT Development for the Upcoming Human Exploration Missions by S. Hu, S. Monadjemi, J. E. Barzilla, E. Semones

“…To enable ARRT to handle variant scenarios of any possible ESPEs in an automatic manner for mission operation, two data sets were employed in developing its modules, one involving historical solar protons recorded over the past four decades and the other using the real‐time telemetry readings of dosimeters onboard International Space Station (ISS). …”
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Liquid biopsy in organ damage: introduction of an innovative tool for assessing the complexity of blunt splenic injury by Aliona Wöhler, Bingduo Wang, Robert Schwab, Veronika Lukacs-Kornek, Arnulf G. Willms, Miroslaw T. Kornek

“…These EVs were found to be significantly elevated in patients with complex spleen injuries (AAST I–IV with hemodynamic instability and need for operative management) in an incremental manner; these patients were typically classified as AAST grade II or higher, which frequently included accompanying solid organ injuries. …”
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Associations between environmental glyphosate exposure and glucose homeostasis indices in US general adults: a national population-based cross-sectional study by Xiaobing Feng, Min Wang, Yuji Wang, Ruyi Liang, Chunxiang Yan

“…Urinary glyphosate demonstrated a statistically significant positive association with FPG and HbA1c in a linear positive dose–response manner, while showing a linear negative association with HOMA2-β. …”
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Local and Deep Features Based Convolutional Neural Network Frameworks for Brain MRI Anomaly Detection by Sajad Einy, Hasan Saygin, Hemrah Hivehch, Yahya Dorostkar Navaei

“…This approach is designed according to combination of DBP-DAE and DSRCN in an end-to-end manner. Extensive experiments conducted based on brain tumor in MRI image public access databases and achieves significant results compared to state-of-the-art algorithms. …”
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Anti-Tumor Effect of Rutin on Human Neuroblastoma Cell Lines through Inducing G2/M Cell Cycle Arrest and Promoting Apoptosis by Hongyan Chen, Qing Miao, Miao Geng, Jing Liu, Yazhuo Hu, Lei Tian, Jingkun Pan, Yi Yang

“…The cell cycle arrest and apoptosis in a dose-dependent manner was measured by flow cytometric and fluorescent microscopy analyses. …”
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Anti-Inflammatory Prostanoids: Focus on the Interactions between Electrophile Signaling and Resolution of Inflammation by Beatriz Díez-Dacal, Dolores Pérez-Sala

“…As for other prostanoids, cyPG effects are highly dependent on context factors and they may exert pro- or anti-inflammatory actions in a cell type–dependent manner, or even biphasic or dual actions in a given cell type or tissue. …”
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English for Agriculture Vocational School Students: A Need Analysis Study at SMK Negeri 2 South Bengkulu by Desi Veranita, Syahrial Syahrial, Irwan Koto

“…Speaking sub-skills classified as; speaking with fluency, attention of choice and pronunciation and using the correct ways/ manners of speaking. Second, English topics for the students of agriculture were the English topics related to the agriculture term. …”
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Incidence and influencing factors of subsyndromal delirium in elderly patients with pancreatic surgery: a prospective study by Hui-Qing Xu, Yun Wang, Ning-Ning Xia, Kuei-Ching Pan, Kuei-Ching Pan

“…In the early postoperative period, special attention should be given to elderly patients with more preoperative comorbidities and lower education levels, and their temperature should be monitored in a timely manner.…”
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Moringa oleifera Flower Extract Suppresses the Activation of Inflammatory Mediators in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages via NF-κB Pathway by Woan Sean Tan, Palanisamy Arulselvan, Govindarajan Karthivashan, Sharida Fakurazi

“…However, it significantly increased the production of IL-10 and IκB-α (inhibitor of κB) in a concentration dependent manner (100 μg/mL and 200 μg/mL). Conclusion. These results suggest that 80% hydroethanolic extract of M. oleifera flower has anti-inflammatory action related to its inhibition of NO, PGE2, proinflammatory cytokines, and inflammatory mediator’s production in LPS-stimulated macrophages through preventing degradation of IκB-α in NF-κB signaling pathway.…”
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Efficacy of Benzocaine and Lidocaine Bioadhesive Patches in Various Minor Oral Surgical Procedures in Children - An Evaluative Study by Nisha E. John, Ramakrishnan Erakkodan, Natta Sreelakshmi

“…In Group 1, custom fabricated Benzocaine patches were placed for 5 minutes at the target site prior to the procedure, and in Group 2, Lidocaine patches were used in the same manner. Each subject completed a visual analogue scale (VAS) and Wong-Baker Faces pain scale (FPS) after each procedure. …”
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