ET-1 Promotes Differentiation of Periodontal Ligament Stem Cells into Osteoblasts through ETR, MAPK, and Wnt/β-Catenin Signaling Pathways under Inflammatory Microenvironment by Li Liang, Wei Zhou, Nan Yang, Jifeng Yu, Hongchen Liu

“…ET-1 promoted differentiation of PDLSCs into osteoblasts by increasing secretion of TNF-α, IL-1β, and IL-6 in a dose- and time-dependent manner. ET-1 also increased expression of Runx2, OCN, and COL1. …”
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Simulating X-ray beam energy and detector signal processing of an industrial CT using implicit neural representations by Edwin Blum, Moritz Burmeister, Florian Stamer, Gisela Lanza

“…INRs excel at representing complex, high-dimensional data in a continuous and differentiable manner, making them a promising substitute for traditional analytical models. …”
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Real-world outcomes of maintenance therapy post-autologous stem cell transplantation in newly diagnosed multiple myeloma by Ka-Won Kang, Dae Sik Kim, Se Ryeon Lee, Mi Hwa Heo, Hyeon-Seok Eom, Jongheon Jung, Ji Hyun Lee, Sung-Hyun Kim, Youngil Koh, Chang-Ki Min, Seung Shin Lee, Sung-Nam Lim, Ho-Young Yhim, Myung-won Lee, Je-Jung Lee, Sung-Hoon Jung, Soo-Mee Bang, Kihyun Kim, the Korean Multiple Myeloma Working party [KMMWP]

“…Therefore, it may be prudent to consider implementing maintenance therapy in a feasible manner.…”
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Investigating the Allelopathic and Bioherbicidal Potential of <i>Solidago altissima</i> with a Focus on Chemical Signaling in <i>Trifolium repens</i> by Ho-Jun Gam, Arjun Adhikari, Yosep Kang, Md. Injamum-Ul-Hoque, Shifa Shaffique, Ji-In Woo, Jin Ryeol Jeon, Byeong-Kwan An, Min Young Back, Ki-Yong Kim, Sang-Mo Kang, In-Jung Lee

“…Moreover, SRE treatment significantly inhibited the seed germination of all tested weed species in a concentration-dependent manner. Gas chromatography-mass spectrometry analysis of <i>S. altissima</i> root extract identified a high concentration of methyl kolavenate, a clerodane diterpene predicted to act as a phytotoxic agent. …”
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Formation mechanism of multiple spallation and its penetration induced by shear localization in NiTi alloy under implosion loading by Xianye Wu, Xiaoyang Pei, Xiang Chen, Hao Zhang, Jin Wang, Xin Yang, Meizhen Xiang, Shang Gao, Fang Wang

“…For larger grain sizes, void nucleation at the first spallation occurs in a coexisting intergranular/transgranular manner, whereas with decreasing grain size, voids tend to nucleate along the grain boundaries. …”
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Research trends relating to body weight control: a systematic review and keyword network analysis of Korea Citation Index Journals (2004–2023) by Yunkyoung Oh, Eunsil Her

“…Conclusion The results of this study showed that weight control research reflecting the characteristics of the times has been steadily progressing in relation to the rapidly increasing obesity in Korea, and when developing policies or setting research directions related to weight loss in the future, research should be conducted in a prospective manner by subdividing it according to groups and interests.…”
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On the Use of SuperDARN Ground Backscatter Measurements for Ionospheric Propagation Model Validation by Joshua J. Ruck, David R. Themens, Pasha Ponomarenko, Angeline G. Burrell, Bharat Kunduri, J. Michael Ruohoniemi, Sean Elvidge

“…Abstract Prior to use in operational systems, it is essential to validate ionospheric models in a manner relevant to their intended application to ensure satisfactory performance. …”
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Hypoxia impairs decitabine-induced expression of HLA-DR in acute myeloid leukaemia cell lines by Sam Humphries, Sean M. Burnard, Courtney D. Eggins, Simon Keely, Danielle R. Bond, Heather J. Lee

“…HMAs act in a replication-dependent manner to remove DNA methylation from the genome. …”
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A division-dependent compartmental model for computing cell numbers in CFSE-based lymphocyte proliferation assays by H. Thomas Banks, W. Clayton Thompson, Cristina Peligero, Sandra Giest, Jordi Argilaguet, Andreas Meyerhans

“…Some key features of a mathematical description of an immune response are an estimate of the number of responding cells and the manner in which those cells divide, differentiate, and die. …”
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A minimal mathematical model for the initial molecular interactions of death receptor signalling by Christian Winkel, Simon Neumann, Christina Surulescu, Peter Scheurich

“…The model allows formation of two distict primary ligand/receptor complexes in a ligand concentration dependent manner. At extremely high ligand concentrations the system is dominated by ligated receptor homodimers.…”
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‘Heavy Waters’ of Punjab: A Hydro-critical Analysis of Bapsi Sidhwa’s Ice-Candy Man by Muhammad Ali

“… This research argues that the seminal Partition novel Ice-Candy Man, written by Bapsi Sidhwa, presents a vision of fluvial Punjab in a manner that fits the idea of “Heavy Waters” presented by Elizabeth DeLoughrey. …”
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Development of proactive mode of providing tax deductions for personal income tax by E. L. Gulkova, M. V. Karp, M. V. Tipalina

“…The authors analysed the practice of application of the simplified procedure for obtaining property and investment tax deductions; statistical data of the Federal Tax Service of Russia on the provision of tax deductions in a simplified manner (1-DDK statistical form “On the declaration of personal income”). …”
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Pharmacological inhibition of key metabolic pathways attenuates Leishmania spp infection in macrophages. by Elaine Carvalho de Oliveira, Rafael Tibúrcio, Gabriela Duarte, Amanda Lago, Léon de Melo, Sara Nunes, Gustavo Gastão Davanzo, Ana Júlia Martins, Bruno Vinagre Ribeiro, Deborah Mothé, Juliana B P Menezes, Patrícia Veras, Natalia Tavares, Pedro M Moraes-Vieira, Cláudia Ida Brodskyn

“…To investigate the metabolic pathways required for Leishmania amastigotes to persist in BMDMs, we pre-treated cells with small molecule drugs that target major metabolic pathways, revealing that perturbations in several metabolic processes affected parasite survival in a strain-independent manner. Treatments with inhibitors of the oxidative phosphorylation and glycolysis substantially reduced parasite loads. …”
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Larvicidal Effect of Vorticella microstoma (Ehrenberg, 1830) on Mosquito Larvae, and Morphological Changes under Induced Environmental Conditions by Achini Koshila Ranasinghe, L. D. Amarasinghe

“…The findings of this study would be considered as the first step for a new avenue to work on environmentally agreeable manner in reducing the Culex spp. mosquito populations.…”
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Case Study: Analyzing CFTR Mutations and SNPs in Pulmonary Fibrosis Patients with Unclear Symptoms by Sahar Yousaf, null Sumaira, Iqbal Bano, Atia Rehman, Samra Kousar, Muhammad Usman Ghani, Mariam Shahid

“…Cystic fibrosis (CF) is a genetic monogenic disorder inherited in an autosomal recessive manner, marked by persistent airway infections in the endobronchial region. …”
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Molecular aspects of cell-penetrating peptides: key amino acids, membrane partners, and non-covalent interactions by Walrant, Astrid, Tazi, Farah, Khemaissa, Sonia, Sagan, Sandrine

“…It separates the external environment from the cell interior and is composed of thousands of different lipids, proteins, and sulfated carbohydrates, all arranged in a complex and dynamic manner and at various length scales. Floating above the lipid bilayer, negatively charged proteoglycans and other polysaccharides form a viscous, anionic matrix layer surrounding animal cells, which CPPs have to go through to reach the lipid bilayer. …”
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β-Glucan induced plasma B cells differentiation to enhance antitumor immune responses by Dectin-1 by Yu Bai, Jun Ding, Liuyang He, Zhichao Zhu, Jie Pan, Chunjian Qi

“…Conclusions These findings reveal that β-glucan can serve as a potent adjuvant to modulate B cell immune responses in a Dectin-1 dependent manner and improve immune checkpoint blockade (ICB) therapy in antitumor. …”
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Mechanistic Insights into the Inhibition of Colorectal Cancer by BuShenFang through Adenomatous Polyposis Coli Expression and Wnt/β-catenin Pathway Regulation by Khang Wen Goh, Jie Ji, Hiu Ching Phang, Xian Gu, Rajesh Sreedharan Nair, Xiaohui Wei, Mohammed Tahir Ansari, Kai Bin Liew

“…Results demonstrated that BSF significantly inhibited the proliferation of CRC cells in a dose-dependent manner. The apoptotic rate was markedly increased in the 20% BSF group, while colony formation, migration, and invasion capabilities of CRC cells were notably suppressed. …”
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Patient's Attitudes Towards the Use of Complementary and Alternative Medicine in Finland: an Ethnomedical Insight Based on Cancer Narratives by Piret Paal

“…However, patients with long-term illnesses are eager to try all available cures in their desire to become well and this leads to a situation in which complementary treatments are used in a somewhat secretive manner. The article follows the discussion concerning the use of complementary and alternative medicine in cancer narratives in order to point out its significance as a part of a self-negotiation process characteristic to the patients with long-term illnesses.…”
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Electrical Stimulation Promotes Cardiac Differentiation of Human Induced Pluripotent Stem Cells by Damián Hernández, Rodney Millard, Priyadharshini Sivakumaran, Raymond C. B. Wong, Duncan E. Crombie, Alex W. Hewitt, Helena Liang, Sandy S. C. Hung, Alice Pébay, Robert K. Shepherd, Gregory J. Dusting, Shiang Y. Lim

“…Beating EBs were also shown to cycle calcium and were responsive to the chronotropic agents, isoproterenol and carbamylcholine, in a concentration-dependent manner. Conclusions. Our results demonstrate that brief electrical stimulation can promote cardiac differentiation of human iPS cells. …”
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