SP600125 Attenuates Nicotine-Related Aortic Aneurysm Formation by Inhibiting Matrix Metalloproteinase Production and CC Chemokine-Mediated Macrophage Migration by Zhen-Zhen Guo, Qun-An Cao, Zong-Zhuang Li, Li-Ping Liu, Zhi Zhang, Ya-Juan Zhu, Guang Chu, Qiu-Yan Dai

“…In vitro, nicotine induced the expression of MCP-1 and RANTES in both RAW264.7 (mouse macrophage) and MOVAS (mouse vascular smooth muscle) cells in a dose-dependent manner; expression was upregulated by 0.5 ng/mL nicotine but strongly downregulated by 500 ng/mL nicotine. …”
Get full text

Development and Validation of a Stability-Indicating HPLC Method for the Simultaneous Determination of trans-Resveratrol and cis-Resveratrol in an Injectable Solution by Esmeralda Mota-Lugo, Mariana Dolores-Hernández, Elvia A. Morales-Hipólito, Iris A. Blanco-Alcántara, Hugo Cuatecontzi-Flores, Raquel López-Arellano

“…An analytical method was obtained by HPLC-PDA, which allowed quantifying the stability of trans-resveratrol in a fast and specific manner in the presence of its degradation products.…”
Get full text

Two-colour QCD phases and the topology at low temperature and high density by Kei Iida, Etsuko Itou, Tong-Gyu Lee

“…In addition, we newly find that around the boundary between the hadronic and BEC phases, nonzero quark number density occurs even in the hadronic phase in contrast to the prediction of the chiral perturbation theory (ChPT), while the diquark condensate approaches zero in a manner that is consistent with the ChPT prediction. …”
Get full text

Long-term stable laser injection locking for quasi-CW applications by Florian Kiesel, Kirill Karpov, Alexandre De Martino, Jonas Auch, Christian Gross

“…By periodical relocking, spectrally pure amplified light is maintained in a quasi-CW manner over long timescales. We characterize the performance of our method for laser diodes amplifying 671 nm light and demonstrate the general applicability by confirming the method to work also for laser diodes at 401 nm, 461 nm and 689 nm. …”
Get full text

Modulation of stress-related behaviour by preproglucagon neurons and hypothalamic projections to the nucleus of the solitary tract by Marie K. Holt, Natalia Valderrama, Maria J. Polanco, Imogen Hayter, Ellena G. Badenoch, Stefan Trapp, Linda Rinaman

“…Through chemogenetic manipulations we reveal that cNTS PPG neurons have the ability to moderately increase anxiety-like behaviours in mice in a sex-dependent manner. Using an intersectional approach, we show that input from the paraventricular nucleus of the hypothalamus (PVN) drives activation of both the cNTS as a whole and PPG neurons in particular in response to acute restraint stress, but that while this input is rich in corticotropin-releasing hormone (CRH), PPG neurons do not express significant levels of receptors for CRH and are not activated following lateral ventricle delivery of CRH. …”
Get full text

Changing Trends in Modeling Mobility by Aarti Munjal, Tracy Camp, Nils Aschenbruck

“…In this work, we summarize the changing trends in modeling human mobility as random movements to the current research efforts that model human walks in a more predictable manner. Mobility patterns significantly affect the performance of a routing protocol. …”
Get full text

On the Design and Development of Planar Monopole Antenna for Bone Crack/Void Detection by Ananda Venkatesan Boologam, Kalimuthu Krishnan, Sandeep Kumar Palaniswamy, Sachin Kumar, Shreya Bhowmik, Nivesh Sharma, Deepesh Vaish, Sourish Chatterjee

“…This method can detect bone fractures in a noninvasive manner. The human arm model is constructed, and the effect of bone cracks of different lengths on the resonating frequency is investigated. …”
Get full text

Norcantharidin induces G2/M arrest and apoptosis via activation of ERK and JNK, but not p38 signaling in human renal cell carcinoma ACHN cells by Huang Shuaishuai, Tuergong Gulimire, Zhu Hangjie, Wang Xue, Weng Guobin, Ren Yu

“…It had also markedly induced apoptosis and G2/M phase cell cycle arrest in a dose-dependent manner by decreasing the expressions of pro-caspase-3, pro-caspase-9, cyclin B1, and pCDC25C while increasing active caspase-3, cleaved-PARP, P21, and pCDC2 levels. …”
Get full text

Flow stress-strain curves and dynamic recrystallization behavior of high carbon low alloy steels during hot deformation by D.Z. Li, X.M. Zhao, H.L. Zhang, J. Li

“…Conversely, at low strain rates, both serrated and bulged grain boundaries can simultaneously be the nucleation sites of DRX grains in a uniform manner. In the DRX type curve, when the strain rate reduced from 0.1 s−1 to 0.01 s−1, the inoculation temperature for the rapid growth of DRX grains in HCLA steel was reduced from 1050 °C to 1000 °C. …”
Get full text

DyCeModel: a tool for 1D simulation for distribution of plant hormones controlling tissue patterning by D. S. Azarova, N. A. Omelyanchuk, V. V. Mironova, E. V. Zemlyanskaya, V. V. Lavrekha

“…Plant hormones are the main regulators of the cell dynamics in plant tissues; they form gradients and maxima and control molecular processes in a concentration-dependent manner. Here, we present DyCeModel, a software tool implemented in MATLAB for one-dimensional simulation of tissue with a dynamic cellular ensemble, where changes in hormone (or other active substance) concentration in the cells are described by ordinary differential equations (ODEs). …”
Get full text

Evaluating the antifibrotic potential of naringenin, asiatic acid, and icariin using murine and human precision‐cut liver slices by Ke Luo, Yana Geng, Dorenda Oosterhuis, Vincent E. deMeijer, Peter Olinga

“…Our findings indicate that NRG reduced collagen type 1 (COL1A1) expression in a concentration‐dependent manner in both mPCLS and chPCLS, decreased fibrosis‐related gene expression, and significantly lowered pro‐collagen type 1 (PCOL1A1) levels in the culture medium by 54 ± 21% (mPCLS) and 78 ± 35% (chPCLS). …”
Get full text

Agricola und das Verkehrte. Zum Umgang mit satztechnischen Idiosynkrasien in Musik des späten 15. Jahrhunderts by Markus Roth

“…. // This essay, starting with the Kyrie I of the Missa Sine Nomine, is dedicated to some remarkable compositional idiosyncracies of Alexander Agricola (1446–1506), of whom his contemporaries attested the talent of “turning things in an unexpected manner” (Hulrich Brätel 1536). Certain paradoxes in the formal composition of late 15th century music appear in Agricola’s work in a strange fashion. …”
Get full text

Crack growth simulation in heterogeneous material by S-FEM and comparison with experiments by Masanori Kikuchi, Yoshitaka Wada, Yulong Li

“…As a result, small surface crack grows in complicated manner.…”
Get full text

Unsupervised Identification for 2-Additive Capacity by Principal Component Analysis and Kendall’s Correlation Coefficient in Multi-Criteria Decision-Making by Xueting Guan, Kaihong Guo, Ran Zhang, Xiao Han

“…With these two kinds of indices, a desired monotone 2-additive capacity is finally identified in an objective and efficient manner. Numerical experiments demonstrate that our proposal can adequately consider the importance of criteria and accurately identify the types of Shapley interaction indices between criteria, and is thus able to produce more convincing and logical results compared with other unsupervised identification methods.…”
Get full text

Minority Narratives: The Voices of Women Architects from the School of Madrid in Early Democratic Spain (1975-1982) by Josenia Hervás y Heras, Eva Hurtado Torán

“…This paper aims to expose, through the chronological sequence of their graduation—initially in a testimonial and isolated manner and later forming small networks—how their professional careers developed. …”
Get full text

Role of lipid binding protein, Niemann pick type C-2, in enhancing shrimp sperm physiological function by Thitiporn Khongkha, Alyssa Rattanadechakul, Piyaporn Surinlert, Orawan Thongsum, Supawich Boonkua, Kessiri Kongmanas, Monsicha Somrit, Wattana Weerachatyanukul, Somluk Asuvapongpatana

“…Finally, the enhanced levels of protein tyrosine phosphorylation and ionophore-induced AR levels in the MrNPC2 treated Tsp significantly increased in a concentration-dependent manner, similar to that of the Vsp sperm. Altogether, our results indicated the importance of MrNPC2 as CHO moderator in sperm membrane, leading to an enhancement in sperm fertilizing ability.…”
Get full text

Voix de revenants dans les Pièces pour danseurs de W.B. Yeats. L’exemple de Ce que rêvent les os by Pierre Longuenesse

“…The action that unfolds before the spectator thus becomes a projection of his imaginary landscape, the “music of the lost kingdom” of memory, brought forth by the power of utterance. In this manner the writing itself becomes the place where dreams can emerge through its capacity to conjure up things that are simultaneously shown to be absent. …”
Get full text

Synthesis and characterization of nano dicalcium phosphate dihydrate from biogenic sources by Md. Kawcher Alam, Md. Sahadat Hossain, Mofassel Hossen Akash, Muhammad Shahriar Bashar, Newaz Mohammed Bahadur, Samina Ahmed

“…In the present study, calcium-enriched marine sources (Turritella, Cardium, and Conch shells) were used to prepare dicalcium phosphate dihydrate (DCPD) in an easy, affordable, and sustainable manner. To produce DCPD, orthophosphoric acid was subjected to a reaction with each type of shell powdered substance, resulting in DCPD in a sheet-like or irregular-type shape. …”
Get full text

A Recognition Method of Athletes’ Mental State in Sports Training Based on Support Vector Machine Model by Yu Li

“…For the opponent, by analyzing the opponent’s psychological state during exercise, the game strategy can be adjusted in real time in a targeted manner, and the probability of winning the game can be provided. …”
Get full text

Anti-Inflammatory and Antioxidant Effects of Carpesium cernuum L. Methanolic Extract in LPS-Stimulated RAW 264.7 Macrophages by Yea-Jin Park, Se-Yun Cheon, Dong-Sung Lee, Divina C. Cominguez, Zhiyun Zhang, Sangwoo Lee, Hyo-Jin An

“…CLME treatment also reduced reactive oxygen species (ROS) generation and enhanced the expression of heme oxygenase-1 (HO-1) protein in a dose-dependent manner in the LPS-stimulated RAW 264.7 cells. Moreover, CLME treatment abolished the nuclear translocation of nuclear factor-κB (NF-κB), enhanced the activation of nuclear factor-erythroid 2 p45-related factor 2 (Nrf2), and reduced the expression of extracellular signal-related kinase (ERK) and ERK kinase (MEK) phosphorylation in LPS-stimulated RAW 264.7 cells. …”
Get full text