Modeling of Blood Flow Dynamics in Rat Somatosensory Cortex by Stéphanie Battini, Nicola Cantarutti, Christos Kotsalos, Yann Roussel, Alessandro Cattabiani, Alexis Arnaudon, Cyrille Favreau, Stefano Antonel, Henry Markram, Daniel Keller

“…We discovered that astrocytic activity impacted blood flow dynamics in a localized, clustered manner, with most vascular segments influenced by two to three neighboring endfeet. …”
Get full text

Paros armados y guerra interna en Colombia, 2000-2022 by Armando José Mercado Vega, Orlando Javier Higuera Torres

“…Se conceptualizaron los paros armados como un tipo de repertorio de violencia usado por grupos irregulares para ejercer su gobernanza armada y demostrar control territorial o mandar un mensaje. A partir de una revisión documental de fuentes secundarias se construyó una base de datos original sobre los paros armados ocurridos en los últimos 22 años en Colombia. …”
Get full text

The effects of the integrative strategy on fostering reflective thinking and imparting basic basketball offensive techniques to female students by Missaa Nadem, Nadeema Badr Mohammed, Huda Badwe Shbeeb, Iqbal Abdul Hussein Neamah, Najlaa Abbas AL-Zuhairi, Nihad Mohammed Alwan

“…Twenty students in-group (B) represent the experimental group, which follows the curriculum that the researcher has developed in an integrated, strategic manner. Result: The method of selecting the (integrative) strategy that was given to the students is right to the level of their skills and characteristics, as well as while taking into consideration the distinct characteristics among them by means of the presentation offered by the stations—from a complete demonstration of the skill, then a slow delivery, then the appearance of the integrated strategy—is also attributed as the reason for the superiority of the members of the experimental group. …”
Get full text

Twenty-Five Years of Evolution and Hurdles in Electronic Health Records and Interoperability in Medical Research: Comprehensive Review by Yun Shen, Jiamin Yu, Jian Zhou, Gang Hu

“…ResultsThe review yielded 2212 studies, all of which were then screened and processed in a structured manner. Of these 2212 studies, 2102 (93.03%) were included in the review analysis, of which 1079 (51.33%) studies were from 2000 to 2009, 582 (27.69%) were from 2010 to 2019, 251 (11.94%) were from 2020 to 2023, and 190 (9.04%) were from 2024. …”
Get full text

A guidance to intelligent metamaterials and metamaterials intelligence by Chao Qian, Ido Kaminer, Hongsheng Chen

“…For intelligent metamaterials, we discuss how artificial intelligence, exemplified by deep learning, streamline the photonic design, foster independent working manner, and unearth latent physics. For metamaterials intelligence, we particularly unfold three canonical categories, i.e., wave-based neural network, mathematical operation, and logic operation, all of which directly execute computation, detection, and inference task in physical space. …”
Get full text

Gastrodin Suppresses the Amyloid β-Induced Increase of Spontaneous Discharge in the Entorhinal Cortex of Rats by Peng-zhi Chen, Hui-hui Jiang, Bo Wen, Shuan-cheng Ren, Yang Chen, Wei-gang Ji, Bo Hu, Jun Zhang, Fenglian Xu, Zhi-ru Zhu

“…The results showed that the spontaneous discharge of EC neurons was increased by local application of soluble Aβ1−42 and that GAS can effectively reverse Aβ1−42-induced facilitation of spontaneous discharge in a concentration-dependent manner. Moreover, whole-cell patch clamp results indicated that the protective function of GAS on abnormal hyperexcitability may be partially mediated by its inhibitory action on Aβ1−42-elicited inward currents in EC neurons. …”
Get full text

How safety leadership, social capital, and safety awareness affect safety citizenship behavior: a mediation perspective by Andjar Budi Wibawanti, Lim Sanny, Denny Siahaan, Sundring Pantja Djati

“…The study employs a causal design and survey methods in a quantitative manner. 120 crew members of passenger ships that were docked at Tanjung Priok Port in Jakarta made up the sample. …”
Get full text

Dexamethasone potentiates the insulin-induced Srebp-1c expression in primary rat hepatocytes by Yan Zhang, Xiangming Fang, Fen Shuang, Guoxun Chen

“…Insulin treatment induced the Srebp-1c expression and suppressed the Pck1 expression in a time-dependent manner. Dex treatment alone reduced the Srebp-1c expression, whereas potentiated the insulin-induced its expression, which reached to a level that was higher than the insulin alone group. …”
Get full text

Narrative analysis of media coverage of Philippines’s tourism policies during the Covid-19 pandemic (2020-2021) by Dickyizmi Syahputra, Dyah Mutiarin

“…The primary objectives of the study are to investigate the manner in which the media in the Philippines covered the Covid-19 outbreak and to investigate the effects that the outbreak had on the public policy of the country with regard to the tourism industry. …”
Get full text

Flavonoids of Rosa rugosa Thunb. inhibit tumor proliferation and metastasis in human hepatocellular carcinoma HepG2 cells by Zhiguo Zhang, Meilin Wang, Shu Xing, Chen Zhang

“…The results indicated that rose flavonoids at low concentration (10–40 μg/mL) had a better inhibitory effect on migration and invasion of HepG2 cells in a dose-dependent manner, while rose flavonoids at high concentration (80–160 μg/mL) could induce apoptosis of HepG2 cells by up-regulating the expression of pro-apoptotic proteins p53 and Bax, and down-regulating the expression of anti-apoptotic proteins Bcl-2, leading to the functioning of caspase-3 and caspase-9. …”
Get full text

The RNA-dependent association of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization. by Martin Sztacho, Jakub Červenka, Barbora Šalovská, Ludovica Antiga, Peter Hoboth, Pavel Hozák

“…Our results show for the first time that the RDPA protein Bromodomain-containing protein 4 (BRD4) associates with PIP2 in the RNA-dependent manner via electrostatic interactions, and that altered PIP2 levels affect the number of nuclear foci of BRD4 protein. …”
Get full text

Influence of Unloading Conditions of Confining Pressure on the Compressive Strength and Permeability of Deep Mudstone by Tianyu Xin, Yashengnan Sun, Junguang Wang, Weiji Sun

“…Under constant axial pressure and unloading of the confining pressure, the mudstone with a depth of 200 m exhibits brittle failure, and the strain fluctuates in a pointwise manner with the increase in axial stress. In this case, the mudstone with a depth of 1000 m exhibits a transition from brittle failure to ductile failure, and the strain fluctuates linearly with the axial stress. …”
Get full text

Nanoscale thickness Octave-spanning coherent supercontinuum light generation by Susobhan Das, Md Gius Uddin, Diao Li, Yadong Wang, Yunyun Dai, Juha Toivonen, Hao Hong, Kaihui Liu, Zhipei Sun

“…Up to octave-spanning coherent light generation with a −40dB spectral width covering from ~565 to 1906 nm is demonstrated in discreate manner via difference-frequency generation, a second-order nonlinear process in gallium selenide and niobium oxide diiodide crystals at the 100-nanometer scale. …”
Get full text

Surface and Catalytic Properties of NiO–FeO Solids Supported on AlO by G.A. El-Shobaky, A.M. Ghozza, N.M. Deraz

“…Furthermore, the amounts of NiO and Fe 2 O 3 in the different solids modified their catalytic activities in different manners.…”
Get full text

Midkine Is a Novel Regulator of Amphetamine-Induced Striatal Gliosis and Cognitive Impairment: Evidence for a Stimulus-Dependent Regulation of Neuroinflammation by Midkine by Marta Vicente-Rodríguez, Rosalía Fernández-Calle, Esther Gramage, Carmen Pérez-García, María P. Ramos, Gonzalo Herradón

“…We found that amphetamine-induced microgliosis and astrocytosis are enhanced in the striatum of MK−/− mice in a region-specific manner. Surprisingly, LPS-induced astrogliosis in the striatum was blocked in MK−/− mice. …”
Get full text

Tolerogenic Splenic IDO+ Dendritic Cells from the Mice Treated with Induced-Treg Cells Suppress Collagen-Induced Arthritis by Jie Yang, Yiming Yang, Huahua Fan, Hejian Zou

“…Collectively, these findings suggest that transferred iTregs could induce tolerogenic characteristics in splenic DCs and these cells could effectively dampen CIA in an IDO-dependent manner. Thus, the potential therapeutic effects of iTregs in CIA are likely maintained through the generation of tolerogenic DCs in vivo.…”
Get full text

Integration of ordered porous materials for targeted three-component gas separation by Xue Jiang, Yu Wang, Hui Wang, Lu Cheng, Jian-Wei Cao, Jin-Bo Wang, Rong Yang, Dong-Hui Zhang, Run-Ye Zhang, Xiu-Bo Yang, Su-Hang Wang, Qiu-Yu Zhang, Kai-Jie Chen

“…Abstract Separation of multi-component mixtures in an energy-efficient manner has important practical impact in chemical industry but is highly challenging. …”
Get full text

Analisis Manajemen Pengelolaan Dana Desa di Desa Jungke Kecamatan Permata Kabupaten Bener Meriah by Irhas Jaya, Humaizi Humaizi, Nurman Achmad

“…Likewise with the Responsibility for the use of village funds so that the community cannot evaluate the results of the work of the village government and the Accountability to the Regional Government which is not carried out in a timely manner. Second: Factors that influence the management of village funds include supporting and inhibiting factors. …”
Get full text

Malathion-Induced Hematoxicity and Its Recovery Pattern in Barbonymus gonionotus by Cynthia E. Mrong, Md. R. Islam, Kamrunnaher Kole, Nusrat N. Neepa, Md. J. Alam, Md. R. Haque, Umme O. Rahman, Golam M. Mostakim

“…Except in the case of the control group (0% of malathion), the obtained results revealed that malathion exposure resulted in significantly (p<0.05) higher prevalence and severity of micronucleus and lower values of Hb, PCV, and RBC and significantly higher values of WBC in a concentration- and time-dependent manner. The values of blood glucose, MCV, MCH, and MCHC showed mixed trends during the experiment. …”
Get full text

Modulation of Preactivation of PPAR-β on Memory and Learning Dysfunction and Inflammatory Response in the Hippocampus in Rats Exposed to Global Cerebral Ischemia/Reperfusion by Ge Kuang, Qin He, Yunmei Zhang, Ruichun Zhuang, Anling Xiang, Qingsong Jiang, Ying Luo, Junqing Yang

“…These effects were significantly improved by pretreatment with GW0742 in the dose-dependent manner. The expressions of IL-1β, IL-6, and TNF-α were increased after GCIRI, while the increases in these proinflammatory cytokines by GCIRI were inhibited by GW0742 pretreatment. …”
Get full text