Cordycepin Decreases Compound Action Potential Conduction of Frog Sciatic Nerve In Vitro Involving Ca2+-Dependent Mechanisms by Li-Hua Yao, Hui-Min Yu, Qiu-Ping Xiong, Wei Sun, Yan-Liang Xu, Wei Meng, Yu-Ping Li, Xin-Ping Liu, Chun-Hua Yuan

“…Results revealed that cordycepin significantly decreased CNAP amplitude and conductive velocity in a reversible and concentration-dependent manner. At 50 mg/L cordycepin, CNAP amplitude and conductive velocity decreased by 62.18 ± 8.06% and 57.34% ± 6.14% compared with the control amplitude and conductive velocity, respectively. …”
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Defense responses of the green microalgae Chlorella vulgaris to the vanadium pentoxide nanoparticles by Kalehjahi Hanifeh Akbarian, Kosari-Nasab Morteza, Amini Mojtaba, Movafeghi Ali

“…According to the obtained results, V2O5 NPs caused a significant reduction in cell number and biomass production of algae in a dose and time dependent manner. Moreover, flow cytometric analysis confirmed a reduction in the quantity of living cells. …”
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An Exponential Active Queue Management Method Based on Random Early Detection by Hussein Abdel-Jaber

“…In this paper, the RED-Exponential Technique (RED_E) is proposed to deal with this issue by dropping arriving packets in an exponential manner without utilizing the maximum packet dropping probability. …”
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Pectin‐decorated selenium nanoparticles as a nanocarrier of curcumin to achieve enhanced physicochemical and biological properties by Yan Wu, Hong Liu, Zhihua Li, Dongye Huang, Lizheng Nong, Zhengxing Ning, Zhizhong Hu, Chunping Xu, Jing‐Kun Yan

“…Antitumour activity assay in vitro demonstrated that pectin‐SeNPs@Cur could inhibit the growth of HepG2 cells in a concentration‐dependent manner, and the nanocarrier pectin‐SeNPs exhibited a low cytotoxic activity against HepG2 cells. …”
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Lactic acid in the vaginal milieu modulates the Candida-host interaction by Diletta Rosati, Marisa Valentine, Mariolina Bruno, Arnab Pradhan, Axel Dietschmann, Martin Jaeger, Ian Leaves, Frank L. van de Veerdonk, Leo A.B. Joosten, Sumita Roy, Mark H. T. Stappers, Neil A.R. Gow, Bernhard Hube, Alistair J.P. Brown, Mark S. Gresnigt, Mihai G. Netea

“…The cell wall of C. albicans cells grown in VSM+LA displayed a robust mannan fibrillar structure, β-glucan exposure, and low chitin content. …”
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CXCL1-Triggered Interaction of LFA1 and ICAM1 Control Glucose-Induced Leukocyte Recruitment during Inflammation In Vivo by Kirsten Buschmann, Lutz Koch, Natascha Braach, Hanna Mueller, David Frommhold, Johannes Poeschl, Peter Ruef

“…We demonstrated that a single injection of glucose rapidly increased blood glucose levels in a dose-dependent manner. Notably, during tumor necrosis factor (TNF) α-induced inflammation leukocyte recruitment was not further enhanced by glucose administration, whereas glucose injection profoundly augmented leukocyte adhesion and transmigration into inflamed tissue in the trauma model, indicating that proinflammatory properties of glucose are stimulus dependent. …”
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Trehalose enhances macrophage autophagy to promote myelin debris clearance after spinal cord injury by Zhida Ma, Congpeng Meng, Xiang Wang, Yuanzhe Zhao, Jingwen Wang, Yihao Chen, Yiteng Li, Yan Jiang, Fangru Ouyang, Jianjian Li, Meige Zheng, Li Cheng, Juehua Jing

“…Results We observed that trehalose significantly enhances macrophage phagocytosis and clearance of myelin in a dose-dependent manner in vitro. In vivo, trehalose administration markedly reduced myelin debris accumulation, inhibited foamy macrophage formation, suppressed inflammatory responses, decreased fibrotic scarring, and promoted axonal growth and motor function recovery after SCI. …”
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The mevalonate pathway contributes to breast primary tumorigenesis and lung metastasis by Javier Conde, Isabel Fernández‐Pisonero, L. Francisco Lorenzo‐Martín, Rocío García‐Gómez, Berta Casar, Piero Crespo, Xosé R. Bustelo

“…In the present study, we report that the expression of mevalonate pathway enzymes is mediated by the RHO guanosine nucleotide exchange factors VAV2 and VAV3 in a RAC1‐ and sterol regulatory element‐binding factor (SREBF)‐dependent manner in breast cancer cells. Furthermore, in vivo tumorigenesis experiments indicated that the two most upstream steps of this metabolic pathway [3‐hydroxy‐3‐methylglutaryl‐coenzyme A synthase 1 (HMGCS1) and 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase (HMGCR)] are important for primary tumorigenesis, angiogenesis, and cell survival in breast cancer cells. …”
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Inflammatory disease progression shapes nanoparticle biomolecular corona-mediated immune activation profiles by Jacob R. Shaw, Nicholas Caprio, Nhu Truong, Mehari Weldemariam, Anh Tran, Nageswara Pilli, Swarnima Pandey, Jace W. Jones, Maureen A. Kane, Ryan M. Pearson

“…NP coronas alter cell associations in a disease-dependent manner, induce differential co-stimulatory and co-inhibitory molecule expression, and influence cytokine release. …”
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Phytochemical, Antioxidant and Mitochondrial Permeability Transition Studies on Fruit-Skin Ethanol Extract of Annona muricata by Wisdom O. Iyanda-Joel, Olusayo B. Ajetunmobi, Shalom N. Chinedu, Emeka E. J. Iweala, Oluwatobi S. Adegbite

“…Lipid peroxidation was induced in a concentration-dependent manner on both the cytosolic and mitochondrial hepatocyte fractions in vitro. …”
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Rosa moschata ameliorates haloperidol-induced Parkinson's disease via reduction of neurodegeneration and oxidative stress by Badriyah S. Alotaibi, Uzma Saleem, Maryam Farrukh, Zunera Chaudhary, Nabia Anwar, Ifat Alsharif, Abdullah R. Alanzi, Tasahil S. Albishi, Fatima A. Jaber, Wedad Saeed Al-Qahtani, Muhammad Ajmal Shah

“…Moreover, histopathological analysis indicated that neurofibrillary tangles and plaques were noticeably decreased in a dose-dependent manner in PD rats treated with R. moschata extract. …”
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Diagnosis of planktonic trophic network dynamics with sharp qualitative changes by Gaucherel, Cedric, Fayolle, Stolian, Savelli, Raphael, Philippine, Olivier, Pommereau, Franck, Dupuy, Christine

“…Aquatic trophic networks are especially dynamic and versatile, thus suggesting new approaches for identifying network structures and functioning in a comprehensive manner.In this study, a qualitative model was devised for this purpose. …”
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Synergistic Antitumour Properties of viscumTT in Alveolar Rhabdomyosarcoma by Rahel Mascha Stammer, Susann Kleinsimon, Jana Rolff, Sebastian Jäger, Angelika Eggert, Georg Seifert, Catharina I. Delebinski

“…Viscum and viscumTT inhibited cell proliferation and induced apoptosis effectively in a dose-dependent manner in vitro and ex vivo, whereas TT showed only moderate inhibitory effects. viscumTT proved to be more effective than the single extracts and displayed a synergistic effect in vitro and a stronger effect in vivo. viscumTT induced apoptosis via the extrinsic and intrinsic pathways, evidenced by the loss of mitochondrial membrane potential and activation of CASP8 and CASP9. …”
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The Transition "School-University": Predictors of Academic Performance of First-year Students by Tatyana Saprykina

“…The presupposition of this study is the notion that educational outcomes of students, among other things, meaningful manner associated with characteristics of learning in high school. …”
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About subjects authorized to carry out investigative (search) actions restricting the invalidity of the housing or other personal ownership by O. V. Salmanov

“…It is concluded that the subjects of investigative (search) actions that limit the inviolability of housing or other property of a person should be defined as persons who on the basis and in the manner prescribed by the criminal procedure legislation of Ukraine, enter into procedural legal relations in connection with conducting a set of cognitive and investigative actions related to the penetration of housing or other property of a person to obtain and verify evidence and information about them. …”
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Sensitive and label-free fluorescent microRNA detection via catalytic DNAzyme assembly initiated primer exchange reaction by Heng Wang, Yi Sun

“…Finally, the created G-quadruplex can fix thioflavin T (ThT) to generate fluorescence signals in a label-free manner. Based on this, the approach demonstrates a high miRNA detection sensitivity with a low limit of detection of 0.32 fM. …”
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Modified French Osteotomy for Cubitus Varus Correction – Our Experience by P. Madhuchandra, K. M. Pawankumar

“…Materials and Methods: Thirty-five patients out of the total 54 patients who underwent modified French osteotomy between January 2013 and December 2021 were evaluated in a retrospective manner. Patients were evaluated using the modified Mayo elbow performance scoring system. …”
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Synthesis of uniform two-dimensional nitrogen-doped graphene films via thermal evaporation as efficient oxygen reduction catalysts by Xue-Wei Lu, Xiaoliang Zhang, Ruxuan Chen, Shuwei Wang, Zile Wang, Huajun Tian, Liying Jiao

“…However, the conventional thermal evaporation techniques present challenges in producing nitrogen-rich NG thin films because of the difficulties of a controllable manner for doping graphene with N atoms. To address this, we designed a vacuum thermal evaporation system for the large-scale preparation of 2D NG thin films. …”
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PMA Induces Vaccine Adjuvant Activity by the Modulation of TLR Signaling Pathway by Dool-Ri Oh, Hu Won Kang, Jong-Ro Kim, Sunoh Kim, In-Kyu Park, Joon Haeng Rhee, Won Keun Oh, Young Ran Kim

“…The 90% EtOH extract from Croton tiglium showed significant NF-κB transactivation in a TLR5-independent manner along with the increase of a flagellin activity. …”
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Chronic Microvascular Complications in Sulfonylureas-Treated Diabetic Patients: Correlations with Glycemic Control, Risk Factors and Duration of the Disease by Luminita-Georgeta Confederat, Roxana Stefan, Mihaela-Iustina Condurache, Oana-Maria Dragostin

“…The information was obtained in a retrospective manner based on the observation sheets of the patients. …”
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