Blood glucose-lowering activity of protocatechuic acid is mediated by inhibiting α-glucosidase by Huafang Ding, Shouhe Huang, Chui Yiu Chook, Erika Kwek, Chi Yan, Kaying Ma, Jianhui Liu, Hanyue Zhu, Zhenyu Chen

“…Driven by hydrogen bonds and van der Waals interactions, PCA reversibly bound with α-glucosidase to form a stable α-glucosidase-PCA complex in a spontaneous manner. The computational simulation found that PCA could insert into the active cavity of α-glucosidase and establish hydrogen bonds with catalytic amino acid residues. …”
Get full text

Defense against Malicious Users in Cooperative Spectrum Sensing Using Genetic Algorithm by Noor Gul, Ijaz Mansoor Qureshi, Atif Elahi, Imtiaz Rasool

“…In cognitive radio network (CRN), secondary users (SUs) try to sense and utilize the vacant spectrum of the legitimate primary user (PU) in an efficient manner. The process of cooperation among SUs makes the sensing more authentic with minimum disturbance to the PU in achieving maximum utilization of the vacant spectrum. …”
Get full text

Delineating Molecular Mechanisms of Squamous Tissue Homeostasis and Neoplasia: Focus on p63 by Kathryn E. King, Linan Ha, Tura Camilli, Wendy C. Weinberg

“…These isoforms can mimic or interfere with one another, and their balance ultimately determines biological outcome in a context-dependent manner. While not frequently mutated, p63, and in particular the ΔNp63 subclass, is commonly overexpressed in human squamous cell cancers. …”
Get full text

Phenazine biosynthesis-like domain-containing protein (PBLD) and Cedrelone promote antiviral immune response by activating NF-ĸB by Peili Hou, Hongchao Zhu, Fengyun Chu, Yan Gao, Xiaonan Sun, Fuzhen Zhang, Xiaomeng Wang, Yueyue Feng, Xingyu Li, Yu Liu, Jun Wang, Xiaoyun Wang, Daniel Chang He, Hongmei Wang, Hongbin He

“…Furthermore, the therapeutic potential of Cedrelone lies in its ability to enhance antiviral immunity in primary macrophages and to promote survival and reduce lung tissue damage in HSV-1-infected mice in a PBLD-dependent manner. Consequently, our findings provide a potential combination model that targets PBLD for Cedrelone antiviral drug therapy, potentially paving the way for the development of broad-spectrum antiviral agents.…”
Get full text

A Novel Trip Coverage Index for Transit Accessibility Assessment Using Mobile Phone Data by Zhengyi Cai, Dianhai Wang, Xiqun (Michael) Chen

“…It enables decision makers to assess transit accessibility in a finer-grained manner on the individual trip level and can be well transformed to measure transit services of other cities.…”
Get full text

Resilient routing in ad hoc wireless sensor networks by Tehmina Karamat Khan, Taimur Karamat, Asad Ullah Shah, Umair Aitimad

“…Ad hoc Wireless Sensor Networks (WSNs) are specialized networks comprising a collection of sensor nodes that communicate to perform a specific task or record data in a decentralized manner. A considerable amount of work has been done regarding security, power saving, and other issues related to ad hoc wireless sensor networks, but there have been fewer efforts to improve performance, optimal utilization, and minimize packet loss. …”
Get full text

An Unsupervised Deep Learning Framework for Retrospective Gating of Catheter-Based Cardiac Imaging by Zheng Sun, Yue Yao, Ru Wang

“…The network was trained on clinical data sets in an unsupervised manner, addressing the difficulty of obtaining the gold standard in deep learning-based motion suppression techniques. …”
Get full text

A New Coupled CFD/Neutron Kinetics System for High Fidelity Simulations of LWR Core Phenomena: Proof of Concept by Jorge Pérez Mañes, Victor Hugo Sánchez Espinoza, Sergio Chiva, Robert Stieglitz

“…By applying codes like CFD (computational fluid dynamics) and SP3 (simplified transport) reactor dynamics it is possible to describe the underlying phenomena in a more accurate manner than by the nodal/coarse 1D thermal hydraulic coupled codes. …”
Get full text

Novel UHF RFID Near-Field Reader Antenna with Uniform Vertical Electric Field Distribution by Yanbin Chen, Xiaojuan Ren, Jimin Zhao, Xin Chen, Yuan Yao, Junsheng Yu, Xiaodong Chen

“…Third, both antennas are fed in a coaxial manner at the center of the antenna. The simulation and measurement results can show that the proposed three-branch antenna and four-branch antenna achieve good impedance matching in the range of 883–960 MHz and 870–960 MHz, respectively, and achieve uniform distribution of the vertical electric field component in a certain area. …”
Get full text

Bayesian Approach for Sequential Probabilistic Back Analysis of Uncertain Geomechanical Parameters and Reliability Updating of Tunneling-Induced Ground Settlements by Cong Li, Shui-Hua Jiang, Jinhui Li, Jinsong Huang

“…The reliability of tunneling-induced ground settlements can be updated in a real-time manner by fully utilizing the time-series monitoring data. …”
Get full text

SPATIAL DISTRIBUTION OF SOME MICROELEMENTS IN SOIL IN THE AL-RIFAI DISTRICT OF THE DHI QAR GOVERNORATE by R. T. Al-Badiri, A. R. Jubier, M. S. Oleiwi

“…The horizons of the pedons were described in a basic morphological manner, and samples were collected from each site for laboratory analyses. …”
Get full text

An Intelligent Framework for Website Usability by Alexiei Dingli, Sarah Cassar

“…As a means of addressing this problem, an Intelligent Usability Evaluation (IUE) tool is proposed that automates the usability evaluation process by employing a Heuristic Evaluation technique in an intelligent manner through the adoption of several research-based AI methods. …”
Get full text

Quercetin as a radiosensitizer for enhanced efficacy of radiotherapy in MCF-7 breast cancer cells by Mohammad Banparvar, Hamid Saeidi Saedi, Mona Haddad Zahmatkesh

“…Conclusions: The study's findings demonstrated that quercetin has the ability to increase the sensitivity of MCF-7 breast cancer cells to ionizing radiation in a manner that depends on the dosage.…”
Get full text

Extensive Growth of an Anaplastic Meningioma by Hajrullah Ahmeti, Homajoun Maslehaty, Athanasios K. Petridis, Alexandros Doukas, Mehran Mahvash, Harald Barth, H. M. Mehdorn

“…A surgical procedure with the aim of complete tumor resection in a curative manner was not possible. Six months after the first operation, due to a new tumor progression, most extensive tumor resection was performed. …”
Get full text

Graph-Attention Diffusion for Enhanced Multivariate Time-Series Anomaly Detection by Vadim Lanko, Ilya Makarov

“…The masked time-series data is then corrupted by noise and reconstructed back by the diffusion model that removes noise in a step-by-step manner. Evaluation on four datasets from various sources demonstrates the effectiveness of our approach, achieving an average <inline-formula><tex-math notation="LaTeX">$F1$</tex-math></inline-formula>-score of 96.51&#x0025;, outperforming many existing baselines. …”
Get full text

Particle Filtering for Obstacle Tracking in UAS Sense and Avoid Applications by Anna Elena Tirri, Giancarmine Fasano, Domenico Accardo, Antonio Moccia

“…In fact, obstacles in the flight path must be detected and tracked in an accurate and timely manner in order to execute a collision avoidance maneuver in case of collision threat. …”
Get full text

Lightweight anomaly detection model for UAV networks based on memory-enhanced autoencoders by HU Tianzhu, SHEN Yulong, REN Baoquan, HE Ji, LIU Chengliang, LI Hongjun

“…The composite statistical characteristics of the data flow were calculated based on the damped window model, and the memory complexity in the calculation process was reduced in an incremental update manner. The hierarchical clustering algorithm was used to divide the composite statistical features, and the separated features were input to multiple small memory-enhanced autoencoders in the integrated architecture for independent training, which reduced the computational complexity and solved the problem of false negatives caused by the overfitting of the reconstruction effect of the traditional autoencoder. …”
Get full text

A Hybrid OFDM-TDM Architecture with Decentralized Dynamic Bandwidth Allocation for PONs by Taner Cevik

“…This information is fed to the bandwidth determination algorithm which is run by each ONU in a distributed manner. Furthermore, Light Load Penalty, which is a phenomenon in optical communications, is mitigated by limiting the amount of bandwidth that an ONU can demand.…”
Get full text

Rapid Sampling of Large Quantities of Interstitial Fluid from Human Skin Using Microneedles and a Vacuum-assisted Skin Patch by Elizabeth Wilkirson, Xue Jiang, Peter Lillehoj

“…The ability to collect ample volumes of ISF in a quick and minimally invasive manner will facilitate the analysis of ISF for biomarker discovery and its use for diagnostic testing.…”
Get full text

Development of unmanned remote smart rescue platform applying Internet of Things technology by Jung Woo Kim, Sang Hun Sul, Jae Boong Choi

“…The real-time monitoring system of unmanned remote smart rescue box is developed in such a manner that the equipment can be checked for theft and damage from external sources. …”
Get full text