Modelling hepatocellular carcinoma microenvironment phenotype to evaluate drug efficacy by Sara Cherradi, Salomé Roux, Marie Dupuy, Séverine Tabone-Eglinger, Edouard Tuaillon, Marianne Ziol, Eric Assenat, Hong Tuan Duong

“…We demonstrated that our model reproduced the Barcelona Clinic Liver Cancer (BCLC) molecular classification, displayed known alterations of epigenetic players, and responded to tyrosine kinase inhibitors (TKIs) such as sorafenib, cabozantinib, and lenvatinib in a patient-dependent manner. Importantly, we reported for the first time that our model correctly predicted 34 clinical outcomes to TKIs out of 37 case studies on 32 HCC patients confirming that patient-centric spheroids, combined with our TICK exclusion strategy, are valuable models for drug discovery and opening a near perspective to personalized care.…”
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Skewing Technology for Permanent Magnet Synchronous Motors: A Comprehensive Review and Recent Trends by Ren Tsunata, Masatsugu Takemoto

“…The definition of skew angle varies across the literature, and one of the purposes of this article is to organize the definition in an easy-to-understand manner. In addition, this article offers three-dimensional finite element analysis (3D-FEA) results of various PMSMs employing the skew for quantitative comparison. …”
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Las mujeres zapatistas reconceptualizan su lucha by Sylvia Marcos

“…Se analizan las re-configuraciones de género emergentes en los discursos de mujeres zapatistas, que provienen de procesos móviles y complejos que revelan concepciones profundamente propias formadas por significados históricos, simbólicos, y epistémicos de enunciaciones como: la paridad-igualdad, la fluidez-dualidad de género, la Tierra Madre benevolente y destructora, el «mandar obedeciendo», la autoridad ejecutora de los acuerdos de la comunidad, el corazón: sede del conocimiento y la organización, la intersubjetividad con la tierra, el entorno y el todo comunal. …”
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A Practical Approach for Identity-Embodied 3D Artistic Face Modeling by Tanasai Sucontphunt

“…This approach can automatically extract the human identity from a 3D human face model and then transfer it to a 3D artistic face model in a controllable manner. Its core idea is to construct a face geometry space and a face texture space based on a precollected 3D face dataset. …”
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Lingual Fibrous Hyperplasia: Case Report and Literature Review by Edison Omar Sacaquirín Zhunio, Julián Alejandro Merel Guamán, Diana Priscila Llivichuzca Inga, Kevin Adrián Quishpe Peña

“…This case highlights the need to adequately characterize the lesions and act in a timely manner to optimize clinical management and patient prognosis.…”
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A Critical Review of Cooperation Systems in Libraries and Information Centers by Hamidreza Radfar, Maryam Salami, Solmaz Noori

“…This resource, which can be considered as an educational resource for students of information and knowledge science and an applied source for specialists and professionals in this science, was critically examined in a descriptive-analytical manner. In this article, after introducing the book, its author and publisher, the structure of the book is mentioned, and then the book is reviewed in both form and content terms. …”
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IMF Sovereign Debt Restructuring Framework: Origin, Evolution and Latest Updates of its Main Components by Alejandro Gabriel Manzo

“…This analytical perspective closes a logical circle that shows the IMF SDR framework in a historical and integral manner and also gives an idealistic insider view to what the Fund is and how it operates.…”
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Beef marbling measurement using spectral imaging: A multiple linear regression approach by Victor Aredo, Lía Ethel Velásquez Castillo, Nikol Siche

“…This study aimed at measuring beef marbling scores in an objective and simple manner through spectral imaging and multiple linear regression (MLR). …”
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Diversité des capitalismes et dispositifs institutionnels environnementaux by Luc Elie

“…The first chapter proposes to highlight the manner in which the coevolution between capitalism and environment was carried out by crossing the theoretical and empirical contributions of the régulation school with environmental history and ecological economics studies. …”
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A Mechanistic, Stochastic Model Helps Understand Multiple Sclerosis Course and Pathogenesis by Isabella Bordi, Renato Umeton, Vito A. G. Ricigliano, Viviana Annibali, Rosella Mechelli, Giovanni Ristori, Francesca Grassi, Marco Salvetti, Alfonso Sutera

“…It is found that a mechanistic model with a random forcing describes in a satisfactory manner the occurrence of relapses and remissions, and the differences in the length of time spent in each one of the two states. …”
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Industrial intelligent network: deepening and upgrading of industrial Internet by Ping ZHANG, Huiyong LIU, Wenjing LI, Fanqin ZHOU

“…Based on the status quo and technological advantages of China's industrial intelligent manufacturing, and aiming to help large, medium and small-sized production enterprises achieve industrial intelligence in a flexible, smooth and cost-controllable manner, the concept of “industrial intelligent network” was proposed to integrate the conditions and advantages in aspects of China's information infrastructure construction, cognitive identification, artificial intelligence, etc., to build an industrial intelligent network, to provide industrial intelligent services to large, medium and small-sized enterprises, so that production enterprises within a broader scale can benefit from intelligent manufacturing with lower costs.…”
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Ni-catalysed acceptorless dehydrogenative aromatisation of cyclohexanones enabled by concerted catalysis specific to supported nanoparticles by Takehiro Matsuyama, Takafumi Yatabe, Tomohiro Yabe, Kazuya Yamaguchi

“…Ni is a promising candidate catalyst as a congener of Pd, but thermally Ni-catalysed dehydrogenative aromatisation has not been reported even in an oxidative manner because of the difficulty of β-hydride elimination and the fast re-insertion of Ni–H species. …”
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Design and Performance Investigation of a Robot-Assisted Flexible Ureteroscopy System by Jianchang Zhao, Jianmin Li, Liang Cui, Chaoyang Shi, Guowu Wei

“…Both phantom and animal experiments validate that the robot has significant advantages over manual operations, including the easy-to-use manner, reduced intraoperative time, and improved surgical ergonomics. …”
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MAIT cells protect against sterile lung injury by Xiawei Zhang, Shuailin Li, Wojciech Lason, Maria Greco, Paul Klenerman, Timothy S.C. Hinks

“…MAIT cells drive the accumulation of type 1 conventional dendritic cells (cDC1s), limiting tissue damage in a DNGR-1-dependent manner. Human scRNA-seq data revealed that MAIT cells were activated, with increased cDC populations in idiopathic pulmonary fibrosis patients. …”
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Achieving Network Localizability in Nonlocalizable WSN with Moving Passive Event by Xiaolei Zhou, Deke Guo, Tao Chen, Xueshan Luo

“…We design a corresponding algorithm in distributed manner for the implementation of our approach. Compared with the current works, our approach requires no extra hardware cost and any adjustment of the current topology of the network and hence is more feasible in practice. …”
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Computational Representation of White Matter Fiber Orientations by Adelino R. Ferreira da Silva

“…Based on experiments, we show that by clustering profile data using mixtures of von Mises-Fisher distributions it is possible to estimate multiple fiber configurations in a more robust manner than currently used approaches, without recourse to regularization or sharpening procedures. …”
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Dans l’ordinateur d’un médiéviste. Peut-on utiliser un logiciel de personal knowledge management pour appliquer une méthode de recherche historique ? by Simon Rozanès

“…Obsidian allows one to navigate through one’s own analyses in a powerful, rapid and easy manner. As for the Zettelkasten method, it can be used to structure one’s analysis, formalise it and build one’s thought.…”
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Converting a controlled vocabulary into an ontology: the case of GEM by Jian Qin, Stephen Paling

“…Conventional knowledge organization tools such as classifications and thesauri resemble ontologies in a way that they define concepts and relationships in a systematic manner, but they are less expressive than ontologies when it comes to machine language. …”
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SUSTAINABLE HUMAN RESOURCE MANAGEMENT RELATIONSHIP WITH THE HUMAN RESOURCE RISK REDUCTION by Azra Ahmić, Selma Smajlović

“…The true objective of this paper was to discover if shaping human resource management in a sustainable manner (with long-term perspective) leads to human resource risk reduction. …”
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Oublier la Renaissance, désapprendre l’humanisme : Le premier Baroque entre exploitation des acquis et table rase imaginaire by Itay Sapir

“…Art history has traditionally postulated a clear break between, on the one hand, late Mannerism, still dependent on Renaissance and humanistic culture, and, on the other hand, the artistic revolution that inaugurated the Baroque. …”
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