Family relationships and caregiver burden among family caregivers of patients with terminal cancer by Boram Kim, In Cheol Hwang, Hong Yup Ahn, Jae-woo Lee

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Profile and outcomes of retinal artery occlusion: The underrealized need to expedite presentation by Yogita Kadam, Anthony V Das, Raja Narayanan, Neelima Balakrishnan, Praneet Telukunta, Brijesh Takkar

“…Methods: Demographic data were analyzed using descriptive statistics. The differential distribution of risk factors of RAO with age was studied. …”
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Bone turnover markers are risk factors for endplate injuries during lumbar interbody fusion: a retrospective case-control study by Tae Hoon Kang, Sung Taek Chung, In-Wook Seo, Minjoon Cho, Jae Hyup Lee

“…Additionally, the ratio (P1NP/CTX) and the subtype groups of BTMs were analyzed. Results The rate of total IEI was 38%. The sex, osteoporosis, spine BMD, femur BMD, CTX, P1NP/CTX, preoperative disc height, and the discrepancy between preoperative disc height and cage size were risk factors in multivariate logistic regression analyses. …”
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Risk factors and prognosis of pulmonary infection in hepatitis B-related acute-on-chronic liver failure: a retrospective cohort study by Neng Wang, Yu Zheng, Shuai Tao, Liang Chen

“…Methods We retrospectively analyzed the clinical data of 393 patients with HBV-ACLF. …”
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Secondary antifungal prophylaxis in hematological malignancy patients with previous invasive fungal disease: a retrospective analysis. by Mingjuan Liu, Yan Li, Yongqing Zhang, Xiaoli Zhao, Bing Zhai, Qingyi Zhang, Lijun Wang, Yu Zhao, Honghua Li, Quanshun Wang, Chunji Gao, Wenrong Huang, Li Yu

“…The clinical characteristics and diagnosis were analyzed according to the diagnostic criteria for IFD. …”
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Determining the Priority of Polysomnography in Obstructive Sleep Apnea Syndrome by Mehmet Sinan Bodur, Barış Çil

“…Statistically significant differences were observed between the groups regarding ESS, BMI, NC, BNP, IVST, ARD, RAD, and PAP max (p<0.05). …”
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Effect of anastomotic reinforcement with barded suture on anastomotic leakage prevention following laparoscopic low anterior resection for rectal cancer: a retrospective single-cen... by Xinyu Qi, Kai Xu, Maoxing Liu, Fei Tan, Pin Gao, Chuanyong Zhou, Zhendan Yao, Nan Zhang, Hong Yang, Chenghai Zhang, Jiadi Xing, Ming Cui, Xiangqian Su

“…Independent risk or protective factors for AL were analyzed using the multivariate logistic regression. …”
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High carbohydrate antigen 19–9 levels indicate poor prognosis in patients with bladder cancer following radical cystectomy by Sang Won So, Sang Won So, Jang Hee Han, Jang Hee Han, Hyeong Dong Yuk, Hyeong Dong Yuk, Chang Wook Jeong, Chang Wook Jeong, Cheol Kwak, Cheol Kwak, Ja Hyeon Ku, Ja Hyeon Ku, Seung-hwan Jeong, Seung-hwan Jeong

“…Recurrence-free survival and overall survival were analyzed using multivariate Cox regression and Kaplan-Meier analyses.ResultsSex distribution, age, body mass index, and underlying diseases (hypertension and diabetes mellitus) were similar between the two groups. …”
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Construction and analysis of a prognostic risk scoring model for gastric cancer anoikis-related genes based on LASSO regression by Ai CHEN, Xiaowei CHEN, Yanan WANG, Xiaobing SHEN

“…Gene expression levels in gastric cancer clinical samples and cells were detected by real-time quantitative PCR (RT-qPCR); Kaplan-Meier (KM) survival curves, univariate and multivariate Cox regression analyses were used to verify the predictive efficiency of the prognostic risk scoring model for the prognosis of gastric cancer patients; CIBERSORT and ESTIMATE algorithms were used to analyze the immune cell infiltration levels in patients with different risk groups; the correlation between risk scores and immune checkpoint expression levels in gastric cancer patients was analyzed using the R package "ggplot2" and "ggExtra", and the correlation between tumor mutation burden (TMB) and risk scores was assessed; chemotherapy drug sensitivity analysis was used to evaluate the value of the constructed prognostic risk scoring model in gastric cancer chemotherapy. …”
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Effects of Different Shaping Methods and Loading on Fruit Quality and Volatile Compounds in ‘Beibinghong’ Grapes by Yingxue Liu, Weiyu Cao, Baoxiang Zhang, Hongyan Qin, Yanli Wang, Yiming Yang, Peilei Xu, Yue Wang, Shutian Fan, Changyu Li, Jiaqi Li, Wenpeng Lu

“…The changes in quality and volatile components of ‘Beibinghong’ grape under different treatments were analyzed by multivariate statistics. The results showed that the inclined horizontal dragon tree significantly increased the net photosynthetic rate and chlorophyll content of leaves, and increased the soluble sugar content and sugar–acid ratio of fruits. …”
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A novel preoperative inflammatory marker prognostic score in patients with localized and metastatic renal cell carcinoma by Rishi R. Sekar, Dattatraya Patil, Yoram Baum, Jeffrey Pearl, Anna Bausum, Mehmet A. Bilen, Omer Kucuk, Wayne B. Harris, Bradley C. Carthon, Mehrdad Alemozaffar, Christopher P. Filson, John G. Pattaras, Peter T. Nieh, Kenneth Ogan, Viraj A. Master

“…Among patients with localized disease, AUC for RISK and LPS was 0.742 and 0.706, respectively (p = 0.456). On multivariate analysis, we observed a step-wise statistically significant inverse relationship between increasing RISK group and OS (all p < 0.001). …”
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Effects of pork protein ingestion prior to and following performing the Army Combat Fitness Test: markers of cognition by Claire Baetge, Kelly Hines, Hudson Lee, Sarah E. Johnson, Adriana Gil, Nicolas D. Barringer, Christopher J. Rasmussen, Ryan Sowinski, Drew E. Gonzalez, Richard B. Kreider

“…Participants returned to the lab in a fasted condition at 0600 after 24, 48, and 72 hours of recovery while being fed 3 MREs daily and having these markers of cognition assessed. Data were analyzed using general linear model statistics and percentage changes from baseline with 95% confidence intervals.Results Multivariate analysis revealed a time (p < 0.001, ηp2 = 0.281) with no treatment ×time effect (p = 0.330, ηp2 = 0.026) for the TMT, wherein the univariate analysis indicated improvements in the time required to complete TMT tasks A (p < 0.001, ηp2 = 0.386) and B (p < 0.001, ηp2 = 0.214) tests, with no interaction effects observed between treatments (p > 0.05). …”
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The Importance of Pan‐Immune‐Inflammation Value Score in Locally Advanced Rectal Cancer by Mahmut Uçar, Mukaddes Yılmaz, Eda Erdiş, Birsen Yücel

“…The 5‐ and 10‐year disease‐free survival (DFS) rates were 67% versus 54% and 56% versus 39% in the PIV‐L and PIV‐H groups, respectively, with the PIV‐H group showing a statistically significantly lower rate (p = 0.048). For DFS, the PIV score was found to be a statistically insignificant prognostic factor in univariate analysis (HR: 0.052, 95% CI: 0.99–2.86, p = 0.052) and recognized as an independent prognostic factor in multivariate analysis (HR: 1.87, 95% CI: 1.08–3.26, p = 0.026). …”
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Technical note: Spectral correction for cavity ring-down isotope analysis of plant and soil waters by G. J. Bowen, S. Banerjee, S. Chakraborty

“…Interference is minimal for soil water but widespread in plant samples, with 13 % and 54 % of samples exhibiting biases larger than 8 ‰ for <span class="inline-formula"><i>δ</i>²H</span> and 1 ‰ for <span class="inline-formula"><i>δ</i>¹⁸O</span>, respectively. We develop multivariate statistical models that use analyzer-reported spectral features to correct for interference. …”
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Chromosomal instability by low-coverage whole-genome sequencing assay predicts prognosis in bladder cancer patients underwent radical cystectomy by Qi Ding, Hailiang Zhu, Bo Fan, Lisheng Wang, Xiaohua Jin, Cheng Cao, Ying Shi, Zhijiang Fan, Wenjian Tu, Feng Li

“…The association between variables and overall and progression-free survival was analyzed using the Cox proportional hazards model. …”
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Cognitive status and influencing factors in maintenance dialysis patients with secondary hyperparathyroidism by LIU Gui-ling, LI Dan-dan, WANG Rui-feng, WANG Xue-rong, CHEN Xiao-li, HAO Li

“…Objective To investigate the cognitive status and influencing factors in maintenance dialysis patients with hyperparathyroidism.Methods According to the level of parathyroid hormone and clinical symptoms,patients with duration of peritoneal dialysis ≥3 months were divided into PTH<630 ng/L group（group A,no-combined bone pain and skin itchy） and PTH >630 ng/L group（group B,combined bone pain and skin itchy）.Detailed history was asked and blood routine,biochemical routine,electrolytes,parathyroid hormone,and 25-dihydroxy vitamin D₃ were determined.Cognitive function was assessed using the modified mini-mental assessment amount（3MS） table in a week after blood tests.The differences in gender,age,history of cerebrovascular disease,hemoglobin,serum creatinine,blood urea nitrogen,uric acid,albumin before,serum albumin,calcium,phosphorus,parathyroid hormone,25-hydroxy vitamin D₃ and 3MS score were analyzed between two groups.The correlations between the 3MS score and other measurement indicators were analyzed.Results There was no significant difference（P>0.05） between two groups in the patient’s gender,age,history of cerebrovascular diseases,serum creatinine,blood urea nitrogen,uric acid,the former plasma albumin,and plasma albumia The levels of hemoglobin,serum calcium,25-hydroxyvitamin D₃levels and 3MS scores in group A were significantly higher than in group B（P<0.05）.The levels of serum phosphorus and serum parathyroid hormone in group B were significantly higher than in group A（P<0.05）.In group A,correlation analysis showed that the 3MS score was negatively correlated with age,the history of cerebral vascular disease and parathyroid hormone levels.In group B,correlation analysis showed that the 3MS score was positively correlated with serum calcium and concentration level of 25-hydroxyvitamin D₃,but negatively correlated with age,the history of cerebrovascular disease,serum phosphate levels and parathyroid hormone levels,and not with gender,hemoglobin concentration,serum creatinine,blood urea nitrogen,uric acid,pre-albumin and serum albumin level.Multivariate stepwise logistic regression analysis revealed statistically significant associations between3 MS and 25-hydroxyl vitamin D₃（P = 0.000）,serum calcium（P = 0.002）,serum phosphate（P =0.089） and parathyroid hormone（P = 0.002）.Conclusions In the maintenance peritoneal dialysis patients with secondary hyperparathyroidism,the overall cognitive level is decreased significantly as compared with those without secondary hyperparathyroidism in peritoneal dialysis patients.The overall cognitive level in the maintenance peritoneal dialysis patients with secondary hyperparathyroidism has a relationship with gender,age,serum calcium and phosphorus,25-hydroxy vitamin D₃ and parathyroid hormone levels.Correcting the metabolic disorders of calcium and phosphorus and reducing parathyroid hormone levels may be an important means to improve cognitive function in peritoneal dialysis patients with secondary hyperparathyroidism.…”
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Correlation between serum total bilirubin level and all cause death and cardiovascular event death in patients with peritoneal maintenance dialysis by LI Jing, LI Luo-hua, JIANG Hong-ying, DONG Yun-ping, LI Yu-feng

“…Spearman correlation analysis was used to analyze the influencing factors of low serum total bilirubin level. …”
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Association of dynamic changes in metabolic syndrome components with clinical outcomes in diffuse large B-cell lymphoma by Dewan Zhao, He Xu, Fengrao Tang, Tongcheng Cui, Xiuli Sun, Guirong Song

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Thinner Central Corneal Thickness is Associated with a Decreased Parapapillary Vessel Density in Normal Tension Glaucoma by Lan-Hsin Chuang, Yeo-Yang Koh, Henry S. L. Chen, Yun-Hsuan Lin, Chi-Chun Lai

“…CCT was measured using the Pentacam® system, optical coherence tomography angiography (OCT-A) was adopted to measure the peripapillary and macular area VDs, and spatial data were based on the Garway–Heath map as illustrated in OCT-A. Univariate and multivariate linear regressions were used to statistically analyze for associations between CCT and other factors. …”
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Survival Analysis of Diabetic Colorectal Cancer Patients on Metformin by Alex Brandon Wong, Ravi Patnaik, Li Ling Chaw, Shir Kiong Lu, Long Chiau Ming, Wen Han Chooi, Ya Chee Lim

“…The study was a retrospective cohort study that included colorectal cancer patients from The Brunei Cancer Center (TBCC) treated between July 2014 and July 2019. Kaplan-Meier and multivariate Cox proportional hazard regression models were used to analyze the data, construct survival curves, and adjust for comorbidities. …”
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