Widely Targeted Metabolomics Reveal the Distribution of Metabolites in Shatian Pomelo Fruit by Jing Wen, Haocheng Liu, Huining Lai, Yujuan Xu, Jijun Wu, Yuanshan Yu, Wenqian Huang, Manqin Fu, Haiyang Liu

“…The differences in metabolite composition and abundance among different tissues were analyzed using multivariate statistical analysis methods. …”
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Development of a novel model for accurate prediction of secondary Candida pneumonia in patients with acute exacerbation of chronic obstructive pulmonary disease by Xiaodan Zhu, Changxing Shen

“…Data were treated and analyzed by R language statistical software.ResultsOf the 164 AECOPD patients, 87 were male and 77 were female, with a mean age of 77.28 ± 8.10 years. …”
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Association between cardiometabolic index and coronary artery calcification in young and middle-aged adults with coronary heart disease by Xi Wu, Mingxing Wu, Haobo Huang, Zhe Liu, He Huang, Lei Wang

“…Results A total of 439 patients were analyzed, of whom 128 were classified as having CAC. …”
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Abnormal GRHL2 Methylation Confers Malignant Progression to Acute Leukemia by Jing Hua, Congcong Ma, Chao Hui Wang, Yan Wang, Saran Feng, Taiwu Xiao, ChuanSheng Zhu

“…We used quantitative real-time polymerase chain reaction (qRT-PCR) for detecting the aberrant expression level of GRHL2 in 60 patients with acute leukemia and 60 normal controls. We analyzed the significant correlation between the expression level of GRHL2 with clinicopathological features and patients’ prognosis in acute leukemia using the corresponding statistical methods. …”
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Untargeted plasma metabolite detection in sudden sensorineural hearing loss: identifying key metabolic signatures by Rongyue Ma, Huangruici Zhang, Weijie Wang, Changping Yu, Guohang Xiong, Qing Li, Yan Wang, Li Zhou, Yu Zhang, Min Li, Min Guo

“…Metabolite profiling was performed, followed by multivariate statistical analyses, including orthogonal projections to latent structures-discriminant analysis (OPLS-DA) and partial least-squares discriminant analysis (PLS-DA) to find differentially expressed metabolites between the groups.ResultsThe results showed significant differences in the plasma metabolome when comparing each of the four SSNHL types with NC. …”
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Comparison of Acute Lobar Nephronia and Acute Pyelonephritis in Children: A Single-Center Clinical Analysis in Southern Taiwan by Wan-Ling Chen, I-Fei Huang, Jiun-Ling Wang, Chih-Hsin Hung, Jer-Shyung Huang, Yao-Shen Chen, Susan Shin-Jung Lee, Kai-Sheng Hsieh, Chia-Wan Tang, Jen-Hung Chien, Yee-Hsuan Chiou, Ming-Fang Cheng

“…The patients with ALN were febrile for longer after antimicrobial treatment, had more nausea/vomiting symptoms, higher neutrophil count, bandemia, and C-reactive protein (CRP) levels, and lower platelet count (all p < 0.05). In multivariate analysis, initial CRP levels, nausea/vomiting symptoms, and fever duration after admission were independent variables with statistical significance to predict ALN. …”
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H-NMR metabolomics identifies three distinct metabolic profiles differentially associated with cardiometabolic risk in patients with obesity in the Di@bet.es cohort by Enrique Ozcariz, Montse Guardiola, Núria Amigó, Sergio Valdés, Wasima Oualla-Bachiri, Pere Rehues, Gemma Rojo-Martinez, Josep Ribalta

“…Then, the association of these clusters with future development of cardiometabolic disease was evaluated using different univariate and multivariate statistical approaches. Moreover, machine learning-based models were built to predict the development of future cardiometabolic disease using BMI and waist-to-hip circumference ratio measures in combination with H-NMR metabolomics. …”
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Relationship Between Domestic Animals, Environmental and Behavioral Factors, and Under-Five Diarrhea in Sidama Region, Ethiopia: A Matched Case-Control Study by Gorfu Geremew, Argaw Ambelu, Dessalegn Dadi, Alemayehu Haddis

“…The random forest (RF) method with the classification RF model was used to compare its findings with those of the multivariate conditional regression analysis. The statistical analyses were conducted using R v.4.3.2 software. …”
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Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study by Mariano Marrodan, María A. Piedrabuena, María A. Zarate, Sofía Rodríguez Murúa, Ezequiel I. Surace, Mauricio F. Farez, Marcela P. Fiol, María C. Ysrraelit, Jorge Correale

“…Statistical analyses included multivariate analyses of covariance (MANCOVA) and Cox regression to identify independent predictors of treatment failure. …”
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Prognostic model of lung adenocarcinoma based on disulfidptosis-related genes and analysis of in vitro cell experiments for PPP1R14B in the model by Yuqing Dong, Ying Zhang, Haoran Liu, Xintong Jiang, Shuyang Xie, Pingyu Wang

“…A risk scores model was constructed through univariate Cox analysis, Lasso analysis, and multivariate Cox analysis. ROC curves and nomogram models were drawn to evaluate the risk model. …”
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Trends in Heart Transplantation and Outcome Analysis: Nationwide Study Using the National Inpatient Sample and Readmission Database by Vivek Joseph Varughese, Aditya Sunil Bhaskaran, Hadrian Hoang-Vu Tran, Nikita Wadhwani, Vignesh Krishnan Nagesh, Izage Kianifar Aguilar, Damien Islek, Simcha Weissman, Adam Atoot

“…Patient characteristics, mortality rates, and readmission patterns were analyzed using ANOVA and multivariate logistic regression, with statistical significance defined as <i>p</i> < 0.05. …”
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Clinical Characteristics and Risk Factors for Severity and Prognosis of Convulsive Status Epilepticus by Zhen Tian, Yingchun Xu, Rundong He, Di Huang, Wanyu Liu, Peiwen Li, Jiasheng Yang, Jie Yang, Jing Ding, Wei Yue

“…Severity, defined as mSTESS ≥ 4, was observed in 65 patients (62.5%), while poor outcomes, indicated by GOS ≤ 3, were noted in 40 patients (38.5%). Multivariate logistic analysis demonstrated that the duration of CSE had a statistically significant impact on severity (mSTESS ≥ 4) (95% CI, 1.06–2.47; p < 0.05). …”
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Evaluation of Key Risk Factors Associated with Postoperative Complications in Colorectal Cancer Surgery by Silviu Stefan Marginean, Mihai Zurzu, Dragos Garofil, Anca Tigora, Vlad Paic, Mircea Bratucu, Florian Popa, Valeriu Surlin, Dan Cartu, Victor Strambu, Petru Adrian Radu

“…Statistical methods included chi-square tests and multivariate logistic regression (significance threshold: <i>p</i> < 0.05). …”
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Reduced Incidence of Aortic Dissection in Patients With Type 2 Diabetes Treated With Sodium Glucose Transporter 2 Inhibitors by Chi‐Jung Chung, Hsin‐Ying Lu, Mu‐Chi Chung, Laing‐You Wu, Chieh Huo, Li‐Kuo Kuo, Chun‐Chieh Liu, Chih‐Pin Chuu

“…The inverse probability of treatment weighting statistical method was performed, which avoids sample loss due to matching. …”
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Prevalence of occupational injuries and associated factors among small scale industry Workers in Harar Town, eastern Ethiopia by Desi Debelu, Sina Temesgen Tolera, Negga Baraki, Dechasa Adare Mengistu

“…Data were collected using pretested questionnaires and observational checklists, covering sociodemographic, occupational injuries, occupational health and safety practices, work environment, and behavioral related factors. The data were analyzed via SPSS version 22, and a p value of &lt;0.05 was considered the cut-off point for statistical significance in multivariate analysis.ResultsOut of the 639 small-scale industry workers included in the current study, 634 provided a response, resulting in a 99.2% response rate. …”
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Palliative care knowledge and self-efficacy: a comparative study between intensive care units and general units nurses by Sahar Fadaei, Mansooreh Azizzadeh Forouzi, Mitsunori Miyashita, Asmaa Jumaa Faleh, Mahlagha Dehghan

“…Convenience Sampling method was used. The data were analyzed using SPSS 23. Descriptive statistics (frequency, percentage, mean, and standard deviation) and inferential statistics (independent t-test, Mann-Whitney U test and multivariate stepwise regression) were employed. …”
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A nomogram integrating clinical stage and pre-EBV DNA to identify the cycles of induction chemotherapy for locoregionally advanced nasopharyngeal carcinoma by Sunqin Cai, Zongwei Huang, Zihan Chen, Ying Li, Jingjing Su, Ronghui Chen, Siqi Xu, Jing Wang, Sufang Qiu

“…Survival outcomes were analyzed using Kaplan-Meier curves, with statistical comparisons performed via the log-rank test. …”
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Wasting and short-term outcomes among children with cancer in resource-limited settings: A prospective study in Uganda. by Richard Nyeko, Jaques van Heerden, Joyce Balagadde Kambugu, Fadhil Geriga, Racheal Angom, Teresa de Rojas, Anouk Neven

“…<h4>Methods</h4>We assessed the wasting status at diagnosis, diagnostic accuracy of visible wasting, and 6-month outcomes of children newly diagnosed with cancer at the UCI (both ambulatory and hospitalized) between April 2022 and March 2023. Data were analyzed using SPSS version 26. Descriptive, bivariate, multivariate, and survival analyses were performed as appropriate. …”
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The predictive value of the preoperative albumin‐to‐fibrinogen ratio for postoperative hospital length of stay in liver cancer patients by Fang Li, Yuetong Ren, Jiacheng Fan, Jin Zhou

“…Methods This retrospective study involved 462 adult HCC patients who underwent partial hepatic lesion excision between February 2016 and August 2022. We analyzed demographic and clinical data, including preoperative blood samples, surgical approach, and LOS. …”
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Association Between High-Density Lipoprotein Cholesterol and Length of Hospital Stay in Acute Pancreatitis: A Retrospective Cohort Study by Qiu L, Xu F, Dong B

“…Data collection adhered to the STROBE guidelines, and baseline clinical and laboratory variables were analyzed. Statistical analysis comprised univariate and multivariate regression models, Generalized Additive Models (GAM), and stratified linear regression models to assess the relationship between HDL-C and LOS, while accounting for confounding factors.Results: After adjusting for key confounders, including age, sex, BMI, WBC, HB, PLT, CRP, ALT, AMY, TB, GLU, LDL-C, SCR, BUN, ALB, Ca2+, and the presence of comorbidities such as hypertension, gallstones, diabetes mellitus, liver dysfunction, renal insufficiency, smoking and alcohol consumption, the study revealed a nonlinear relationship between HDL-C levels and LOS, with an inflection point at 1.5 mmol/L. …”
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