Unconventional hexagonal open Prussian blue analog structures by Jinwen Yin, Jing Wang, Mingzi Sun, Yajie Yang, Jia Lyu, Lei Wang, Xinglong Dong, Chenliang Ye, Haibo Bao, Jun Guo, Bo Chen, Xichen Zhou, Li Zhai, Zijian Li, Zhen He, Qinxin Luo, Xiang Meng, Yangbo Ma, Jingwen Zhou, Pengyi Lu, Yunhao Wang, Wenxin Niu, Zijian Zheng, Yu Han, Daliang Zhang, Shibo Xi, Ye Yuan, Bolong Huang, Peng Guo, Zhanxi Fan

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Association of rs3755319 and rs4148325 of the <i>UGT1A1</i> gene, rs2328136 of the <i>NUP153-AS</i> gene, and rs16928809 of the <i>SLC22A18</i> gene with benign unconjugated hyperb... by Anastasiya A. Ivanova, Natalia E. Apartseva, Anastasiia P. Kashirina, Elena G. Nemcova, Julija V. Ivanova, Margarita V. Kruchinina, Svetlana A. Kurilovich, Vladimir N. Maksimov

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Optimal timing of organs-at-risk-sparing adaptive radiation therapy for head-and-neck cancer under re-planning resource constraints by Fatemeh Nosrat, Cem Dede, Lucas B. McCullum, Raul Garcia, Abdallah S.R. Mohamed, Jacob G. Scott, James E. Bates, Brigid A. McDonald, Kareem A. Wahid, Mohamed A. Naser, Renjie He, Aysenur Karagoz, Amy C. Moreno, Lisanne V. van Dijk, Kristy K. Brock, Jolien Heukelom, Seyedmohammadhossein Hosseinian, Mehdi Hemmati, Andrew J. Schaefer, Clifton D. Fuller

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Diagnostic pathways for breast cancer in 10 International Cancer Benchmarking Partnership (ICBP) jurisdictions: an international comparative cohort study based on questionnaire and... by David Weller, Usha Menon, Alina Zalounina Falborg, Henry Jensen, Andriana Barisic, Anne Kari Knudsen, David H Brewster, Victoria Cairnduff, Eva Grunfeld, Elizabeth Harland, Mats Lambe, Rebecca-Jane Law, Yulan Lin, Martin Malmberg, Donna Turner, Richard D Neal, Victoria White, Samantha Harrison, Peter Vedsted, Una MacLeod, Conan Donnelly, Anna Gavin, Jon Emery, Oliver Bucher, Jatinderpal Kalsi, Chantelle Anandan, Evangelia Ourania Fourkala, Therese Kearney, Marie-Louise Essink-Bot, Sigrun Saur Almberg, Breann Hawryluk, Jacqueline Kelly, Jackie Boylan, Jan Willem Coebergh, David Brewster, Stefan Bergström, Victoria Hammersley, Rebecca Bergin, Alina Zalounina Falborg, Andriana Barisi, Kerry Moore, Maria Rejmyr Davis

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Sorafenib as Adjuvant Therapy Post–Liver Transplant: A Single-center Experience by Hala Hassanain, MD, Ashton A. Connor, MD, PhD, Elizabeth W. Brombosz, PhD, Khush Patel, MD, MS, Ahmed Elaileh, MD, Tamneet Basra, MD, Sudha Kodali, MD, MSPH, David W. Victor, III, MD, Caroline J. Simon, MD, Yee Lee Cheah, MD, Mark J. Hobeika, MD, Constance M. Mobley, MD, PhD, Ashish Saharia, MD, Sadhna Dhingra, MD, Mary Schwartz, MD, Anaum Maqsood, MD, Kirk Heyne, MD, Ahmed O. Kaseb, MD, Jean-Nicolas Vauthey, MD, A. Osama Gaber, MD, Maen Abdelrahim, MD, PhD, R. Mark Ghobrial, MD, PhD

“…Hepatocellular carcinoma (HCC) has a rising incidence and mortality in North America. Liver transplantation (LT) with adjunctive therapies offers excellent outcomes. …”
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Clinical Guidelines of the Russian Society of Surgeons, the Russian Gastroenterological Association, the Association of Surgeons-Hepatologists and the Endoscopic Society “REndO” o... by V. T. Ivashkin, A. G. Kriger, A. V. Okhlobystin, M. A. Anischenko, S. S. Kardasheva, S. A. Alekseenko, S. F. Bagnenko, M. I. Bykov, S. A. Budzinskiy, I.  M. Buriev, V. A. Vishnevskiy, E. I. Galperin, V. P. Glabay, V. R. Goltsov, T. G. Dyuzheva, G. G. Karmazanovskiy, M. P. Korolev, D. M. Krasilnikov, Yu. A. Kucheryavy, I. V. Maev, N. A. Maystrenko, M. F. Osipenko, M. I. Prudkov, V. I. Simanenkov, E. G. Solonitsin, A. V. Fedorov, E. D. Fedorov, I. B. Khlynov, M. V. Chikunova, A. V. Shabunin, S. G. Shapovalyants, A. A. Sheptulin, O. S. Shifrin

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Hard rock aquifer architecture and water circulation levels in the Strengbach critical zone observatory (France) by Chabaux, François, Négrel, Philippe, Gal, Frederick, Viville, Daniel, Ranchoux, Coralie, Van der Woerd, Jérome, Delay, Frederick, Ackerer, Julien, Aquilina, Luc, Diraison, Marc, Masson, Frédéric, Mériaux, Anne-Sophie, Labasque, Thierry, Lucas, Yann, Pezard, Philippe Adrien, Reuschlé, Thierry, Schmitt, Anne-Désirée, Stille, Peter, Wyns, Robert, Lerouge, Catherine, Dezayes, Chrystel

“…The latter is subdivided into a few meters thick saprock horizon, defined by open sub-horizontal fractures and a deeper fractured bedrock horizon with steeply dipping fractures (${>}$50°). In the north-facing slope, the vertical extension of the mobile saprolite horizon increases from ${\approx }$1–2 m at the top of the slope to ${\approx }$9 m downstream, close to the valley bottom. …”
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Frailty-adjusted therapy in Transplant Non-Eligible patients with newly diagnosed Multiple Myeloma (FiTNEss (UK-MRA Myeloma XIV Trial)): a study protocol for a randomised phase III... by Roger Owen, John Jones, David Meads, David A Cairns, Christopher Parrish, Gordon Cook, Neil Rabin, Matthew Jenner, Martin Kaiser, Kevin Boyd, Graham Jackson, Catherine Olivier, Amy Beth Coulson, Kara-Louise Royle, Charlotte Pawlyn, Anna Hockaday, Jennifer Bird, Stella Bowcock, Ruth de Tute, Hayley Gardner, Bryony Dawkins, Rowena Henderson, Phillip Best, Bhuvan Kishore, Mark Drayson

“…Following 12 cycles of induction treatment, participants alive and progression free will undergo a second (double-blind) randomisation on a 1:1 basis to maintenance treatment with lenalidomide+placebo versus lenalidomide+ixazomib until disease progression or intolerance.Ethics and dissemination Ethical approval has been obtained from the North East—Tyne &amp; Wear South Research Ethics Committee (19/NE/0125) and capacity and capability confirmed by local research and development departments for each participating centre prior to opening to recruitment. …”
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Assessing intrinsic capacity for person‐centred HIV care: a cross‐sectional study in ageing populations in Malaysia and Hong Kong by Reena Rajasuriar, Syaza Hisham, John Son Lim, Jean Yi Cheong, Wen Ying Ho, Siew Hwei Yap, Nurul Syuhada Zulhaimi, Malinee Neelamegam, Catherine Cheung, Vivian Wong, Ruhana Che Yusof, Kejal Hasmukharay, Shahrul Bahyah Kamaruzzaman, Sharifah Faridah Syed Omar, Meng Li Chong, Pui Li Wong, Grace Chung‐Yan Lui

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Prostate cancer incidence and mortality linked to metalworking fluid exposure: a systematic review and meta-analysis by Zahra Moradpour, Amin Barik, Goljamal Jorjani, Mohammad Reza Taherian, Sepideh Tousizadeh, Sepideh Tousizadeh, Aram Halimi, Aram Halimi, Yaser Soleimani, Mobina Karimian, Tina Khavari, Fateme Azizi Kalankari, Fatemeh Asadipour, Mojtaba Azari, Niloofar Yousefzadeh Shakouri, Saeideh Karamian, Nasser Bahari, Alireza Mosavi Jarrahi

“…BackgroundProstate cancer is the second most diagnosed cancer in men globally, with high prevalence in North America, Europe, and Australia. Occupational exposures, including metalworking fluids (MWFs), have emerged as a potential risk factor for prostate cancer, yet comprehensive studies on this association are limited.ObjectiveThis study aims to systematically review and conduct a meta-analysis to examine the incidence and mortality of prostate cancer linked to MWF exposure.MethodsA systematic review and meta-analysis were conducted following the PRISMA guidelines. …”
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Efficacy and Safety of High-dose versus Standard-dose Prazosin in Paediatric Scorpion Envenomation: A Single-blinded Randomised Controlled Study by Apoorva Gayatri Abbadi, Hidaytullah R Bijapure, Chandrika R Doddihal, Bhavana B Lakhkar, Y Rohith, VJ Prakash, Kumar BM Prasanna, Mallanagouda Patil

“…Aim: To evaluate and compare the efficacy and safety of standard-dose versus high-dose prazosin protocols in managing paediatric scorpion envenomation in a tertiary care hospital in North Karnataka, India. Materials and Methods: A single-blinded randomised controlled study was conducted in Paediatric Intensive Care Unit (PICU) at BLDE DU Shri BM Patil Medical College Hospital and Research Centre, Vijayapur, Karnataka, India, from January 2017 to December 2022. …”
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High prevalence of resistance to macrolides and fluoroquinolones in Mycoplasma genitalium isolated from patients in two Russian megalopolises – Moscow and St. Petersburg in 2021– 2... by Edelstein I.A., Gushchin A.E., Gladin D.P., Romanov A.V., Negasheva E.S., Frigo N.V., Kozlov R.S., Potekaev N.N., Kozlova N.S., Borukhovich D.G.

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Beneficial and harmful effects of duloxetine versus placebo, ‘active placebo’ or no intervention for adults with major depressive disorder: a systematic review with meta-analysis a... by Christian Gluud, Marija Barbateskovic, Joanna Moncrieff, Faiza Siddiqui, Janus C Jakobsen, Mathias Maagaard, Sophie Juul, Johanne Juul Petersen, Caroline Barkholt Kamp, Mark Abie Horowitz, Kiran Kumar Katakam

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Risk of SARS-CoV-2 infection among front-line healthcare workers in Northeast Brazil: a respondent-driven sampling approach by Thalia Velho Barreto de Araújo, Demócrito de Barros Miranda-Filho, Ricardo Arraes de Alencar Ximenes, Ulisses Ramos Montarroyos, Celina Maria Turchi Martelli, Maria de Fátima Pessoa Militão de Albuquerque, Wayner Vieira de Souza, Cresio Romeu Pereira, Cynthia Braga, Celia Landmann Szwarcwald, Paulo Roberto Borges de Souza-Junior, Morgana Nascimento Xavier, Clarice Neuenschwander Lins de Morais, Gabriela Diniz Militao de Albuquerque, Cristiane Bresani-Salvi, Carolline Araújo Mariz, Noemia Teixeira de Siqueira-Filha, Jadson Mendonça Galindo, Cláudio Luiz França-Neto, Jessyka Mary Vasconcelos Barbosa, Maria Amelia Sousa Mascena Veras, Luana Nepomuceno Gondim Costa Lima, Luciane Nascimento Cruz, Carl Kendall, Ligia Regina Franco Sansigolo Kerr

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Utilization of patient-reported outcomes to assess adherence to relugolix when combined with stereotactic body radiation therapy for intermediate to high-risk prostate cancer by Kelly Gaudian, Min Jung Koh, Min Ji Koh, Ryan R. Collins, Shaine Eden, Zoya Zwart, Malika Danner, Alan Zwart, Mark Fallick, Deepak Kumar, Paul Leger, Nancy A. Dawson, Simeng Suy, Sean P. Collins

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Investigating the Effect of Chicken Manure and Potassium Sulfate on the Physiological Properties of Fenugreek )Trigonella foenum-graecum L.( Medicinal Plant by Mohammad hossein Aminifard, Sajjad Nadafa, Hassan Hassan, Mehdi Jahani

“…Therefore, considering the mentioned cases and the lack of scientific information in the field of combining fertilizers, in this research, an attempt was made to find a suitable fertilizer combination consisting of chicken manure and potassium sulfate for the fenugreek plant.Materials and MethodsTo investigate the effect of chicken manure and potassium sulfate on the physiological characteristics of the fenugreek medicinal plant, factorial research was conducted based on randomized complete block design with three replications in the crop year 2021-2022 in Qochan city in the north of Razavi Khorasan province. Experimental treatments included chicken manure at three levels (0, 1000, and 2000 kg. h-1) and potassium sulfate at four levels (0, 1.5, 3, and 5 per thousand). …”
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Genome-Wide Approach Identifies Natural Large-Fragment Deletion in ASFV Strains Circulating in Italy During 2023 by Claudia Torresi, Roberta Biccheri, Cesare Cammà, Carmina Gallardo, Maurilia Marcacci, Simona Zoppi, Barbara Secondini, Caterina Riverso, Alejandro Soler, Cristina Casciari, Michela Pela, Elisabetta Rossi, Claudia Pellegrini, Carmen Iscaro, Francesco Feliziani, Monica Giammarioli

“…In this study, ASFV strains collected in Italy during 2022–2023 from two geographical clusters, North-West (Alessandria) and Calabria, were fully sequenced. …”
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MOMENT registry: Patients with advanced non-small-cell lung cancer harboring MET exon 14 skipping treated with systemic therapy by Michael Thomas, Petros Christopoulos, Wade T Iams, Julien Mazieres, Alexis B Cortot, Nir Peled, Gabriele Minuti, Egbert F Smit, Francois Audhuy, Karin Berghoff, S Peter Eggleton, Frank Fries, Maike Hildenbrand, Peter Liu, Seyed Hamidreza Mahmoudpour, Christoph Menzel, Dina Oksen

“…Registry site inclusion is dependent on confirmation that local METex14 skipping detectionmethods are sufficient to confirm METex14 skipping status.MOMENT is currently active at more than 60 sites across Europe and North America and approximately 700 patients are expected to be enrolled within the next 4 years. …”

Life after prostate cancer diagnosis: protocol for a UK-wide patient-reported outcomes study by David H Brewster, Victoria Cairnduff, Eila Watson, Amy Downing, Adam W Glaser, Penny Wright, William Cross, Conan Donnelly, Anna Gavin, Carol Rivas, Richard Wagland, Peter Selby, Luke Hounsome, Therese Kearney, Rebecca Mottram, Majorie Allen, Oonagh McSorley, Hugh Butcher, Paul Kind, James W H Catto, Dyfed Huws, Emma McNair, Lauren Matheson, Johana Nayoan, Mike Horton, Jessica Corner, Julia Verne

“…To ensure detailed understanding of issues of importance, qualitative interviews will be undertaken with a sample of men who complete the survey across the UK (n=∼150) along with a small number of partners/spouses (n=∼30).Ethics and dissemination The study has received the following approvals: Newcastle and North Tyneside 1 Research Ethics Committee (15/NE/0036), Health Research Authority Confidentiality Advisory Group (15/CAG/0110), NHS Scotland Public Benefit and Privacy Panel (0516-0364), Office of Research Ethics Northern Ireland (16/NI/0073) and NHS R&amp;D approval from Wales, Scotland and Northern Ireland. …”
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A multicenter, randomized, double-blind, placebo-controlled phase 3 study of Socazolimab or placebo combined with carboplatin and etoposide in the first-line treatment of extensive... by Zhiwei Chen, Jianhua Chen, Dingzhi Huang, Wei Zhang, Lin Wu, Tienan Yi, Qiming Wang, Liang Han, Liping Tan, Yinyin Li, Zhihong Zhang, Na Li, Jie li, Tongmei Zhang, Ying Hu, Hongmei Sun, Youhua Wu, Zhiyong He, Runxiang Yang, Peng Cheng, Xingya Li, Jianhua Shi, Guohua Yu, Daiyuan Ma, Benjamin Xiaoyi Li, Xiangrong Dai, Michael Wong, Yujie Li, Xiaohui Yu, Shun Lu, for the Socazolimab Study Group

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