Is There an Association between Bell Palsy in Pediatric Patients and COVID-19? by Mohamed E. El-Deeb, Saad Elzayat, Abeer Salamah, Ali Gamal, Shimaa Elgamal, Ahmed El-Sobki

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Marijuana Compounds: A Nonconventional Approach to Parkinson’s Disease Therapy by Mariana Babayeva, Haregewein Assefa, Paramita Basu, Sanjeda Chumki, Zvi Loewy

“…This therapy improves only motor symptoms of Parkinson’s disease and is associated with a number of adverse effects including dyskinesia. …”
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Microglial Ion Channels as Potential Targets for Neuroprotection in Parkinson’s Disease by Jason R. Richardson, Muhammad M. Hossain

“…It is thought that the loss of neurons and development of inclusion bodies occur gradually over decades until they progress to the point where ~60% of the dopamine neurons are lost and patients present with motor dysfunction. …”
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Olfactory dysfunction as potential biomarker in neurodegenerative diseases: a narrative review by Nicolas De Cleene, Katarína Schwarzová, Samuel Labrecque, Clancy Cerejo, Atbin Djamshidian, Klaus Seppi, Beatrice Heim

“…Neurodegenerative diseases represent a group of disorders characterized by progressive degeneration of neurons in the central nervous system, leading to a range of cognitive, motor, and sensory impairments. …”
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Brainstem serotonin amplifies nociceptive transmission in a mouse model of Parkinson’s disease by Zoé Grivet, Franck Aby, Aude Verboven, Rabia Bouali-Benazzouz, Benjamin Sueur, François Maingret, Frédéric Naudet, Thibault Dhellemmes, Philippe De Deurwaerdere, Abdelhamid Benazzouz, Pascal Fossat

“…Abstract Parkinson’s disease arises from the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to motor symptoms such as akinesia, rigidity, and tremor at rest. …”
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N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis by Mariana O. Ribeiro, Mafalda Oliveira, Verónica Nogueira, Vítor Costa, Vitor Teixeira

“…Mutations in BSCL2, particularly N88S and S90L, lead to seipinopathies, which correspond to a cohort of motor neuron diseases (MNDs) characterized by the accumulation of misfolded N88S seipin into inclusion bodies (IBs) and cellular dysfunctions. …”
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An Integrated Review of Psychological Stress in Parkinson’s Disease: Biological Mechanisms and Symptom and Health Outcomes by Kim Wieczorek Austin, Suzanne Weil Ameringer, Leslie Jameleh Cloud

“…The results revealed significant associations between psychological stress and increased motor symptom severity and loss of dopamine-producing neurons in animal models of PD and between psychological stress and increased symptom severity and poorer health outcomes in human subjects with PD. …”
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Crocetin Alleviates Inflammation in MPTP-Induced Parkinson’s Disease Models through Improving Mitochondrial Functions by Na Dong, Zhong Dong, Ying Chen, Xiaosu Gu

“…Our results showed that crocetin treatment attenuates MPTP-induced motor deficits and protects dopaminergic neurons. …”
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Case report: Suspected propofol associated Heinz body anemia in five mechanically ventilated dogs: a historical case series by Emily M. Ireland, Claire R. Sharp, Ellie M. Leister, Susan Boyd

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Cortical thickness correlated with peripheral inflammatory cytokines in amyotrophic lateral sclerosis by Jing Yang, Jing Yang, Jing Yang, Wenyi Li, Wenyi Li, Wenyi Li, Mei Tian, Mei Tian, Mei Tian, Lei Zhang, Fengping Du, Fengping Du, Fengping Du, Xin Li, Xin Li, Xin Li, Qi Liu, Qi Liu, Qi Liu, Rui Li, Rui Li, Rui Li, Zhenzhong Li, Zhenzhong Li, Zhenzhong Li, Hui Dong, Hui Dong, Hui Dong, Yaling Liu, Yaling Liu, Yaling Liu

“…IntroductionAmyotrophic lateral sclerosis (ALS) is a rare, devastating neurodegenerative disease that affects upper and lower motor neurons, resulting in muscle atrophy, spasticity, hyperreflexia, and paralysis. …”
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Whole transcriptome analysis of unmutated sporadic ALS patients' peripheral blood reveals phenotype-specific gene expression signature by Francesca Dragoni, Maria Garofalo, Rosalinda Di Gerlando, Bartolo Rizzo, Matteo Bordoni, Eveljn Scarian, Camilla Viola, Veronica Bettoni, Giuseppe Fiamingo, Danilo Tornabene, Lucia Scanu, Orietta Pansarasa, Luca Diamanti, Stella Gagliardi

“…The work proposed stress the innovative view of ALS as a multi-systemic disorder rather than a pure motor neuron-associated and ‘neurocentric’ pathology. …”
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Safety and Efficacy of Nusinersen Focusing on Renal and Hematological Parameters in Spinal Muscular Atrophy by Hüseyin Bahadır Şenol, Gizem Yıldız, Ayşe İpek Polat, Adem Aydın, Ayşe Semra Hız, Alper Soylu, Uluç Yiş

“…ABSTRACT Background Spinal muscular atrophy (SMA) is a motor neuron disease caused by mutations in the SMN1 gene. …”
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M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b by Chiara Parisi, Giulia Napoli, Pablo Pelegrin, Cinzia Volonté

“…Mutations in over twenty genes associated with familial forms of ALS have provided insights into the mechanisms leading to motor neuron death. …”
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Identification of a metabolic brain network characterizing essential tremor by Solange Volnov, Hamzah Baagil, Oliver Winz, Hans-Juergen Kaiser, Sanne Katherina Meles, Joerg Bernhard Schulz, Kathrin Reetz, Felix Manuel Mottaghy, Florian Holtbernd

“…Our findings suggest ET is characterized by an abnormal brain network associated with disease phenotype.…”
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A riboflavin-responsive neuronopathy with unique characteristics: Brown-Vialetto- Van Laere syndrome by Soreya BELARBI, Samira Makri MOKRANE

“…Sometimes the clinical spectrum mimics juvenile-onset motor neuron disease (MND). It is important to identify BVVLS that may respond to high doses of riboflavin. …”
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A riboflavin-responsive neuronopathy with unique characteristics: Brown-Vialetto- Van Laere syndrome by Soreya BELARBI, Samira Makri MOKRANE

“…Sometimes the clinical spectrum mimics juvenile-onset motor neuron disease (MND). It is important to identify BVVLS that may respond to high doses of riboflavin. …”
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Current Status of Treatment of Spinal and Bulbar Muscular Atrophy by Fumiaki Tanaka, Masahisa Katsuno, Haruhiko Banno, Keisuke Suzuki, Hiroaki Adachi, Gen Sobue

“…Spinal and bulbar muscular atrophy (SBMA) is the first member identified among polyglutamine diseases characterized by slowly progressive muscle weakness and atrophy of the bulbar, facial, and limb muscles pathologically associated with motor neuron loss in the spinal cord and brainstem. …”
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Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity by Dwaine F. Emerich, Jeffrey H. Kordower, Yaping Chu, Chris Thanos, Briannan Bintz, Giovanna Paolone, Lars U. Wahlberg

“…Animals were evaluated using a battery of validated motor tests, and histology was performed to determine the extent of GDNF diffusion and associated prevention of neuronal cell loss and behavioral deficits. …”
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In vivo mapping of sodium homeostasis disturbances in individual ALS patients: A brain 23Na MRI study. by Aude-Marie Grapperon, Mohamed Mounir El Mendili, Adil Maarouf, Jean-Philippe Ranjeva, Maxime Guye, Annie Verschueren, Shahram Attarian, Wafaa Zaaraoui

“…ALS patients with limited TSC increase had slower progression of disability or predominant lower motor neuron phenotype or shorter disease duration.…”
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Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder by Claudia Fuchs, Laura Gennaccaro, Stefania Trazzi, Stefano Bastianini, Simone Bettini, Viviana Lo Martire, Elisa Ren, Giorgio Medici, Giovanna Zoccoli, Roberto Rimondini, Elisabetta Ciani

“…These defects are associated with neuroanatomical alterations, such as reduced dendritic arborization and spine density of hippocampal neurons. …”
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