Spectral and coupling characteristics of somatosensory cortex and centromedian thalamus differentiate between pre- and inter-ictal 5–9 Hz oscillations in a genetic rat model of abs... by Eleni Nikalexi, Vladimir Maksimenko, Thomas Seidenbecher, Thomas Budde, Hans-Christian Pape, Annika Lüttjohann

“…The present study characterizes the profile of 5–9 Hz oscillations in thalamo-cortical circuits during pre- and inter-ictal states.Here we recorded local-field-potentials in S1, CM and the secondary motor cortex of GAERS. Time-frequency analysis was used to assess spectral power and non-linear-association analysis was used to determine coupling strength and directionality between brain areas. …”
Get full text

Prevalence and Risk Factors for Minor Hallucinations in Patients with Parkinson’s Disease by Min Zhong, Ruxin Gu, Sha Zhu, Yu Bai, Zhuang Wu, Xu Jiang, Bo Shen, Jun Zhu, Yang Pan, Jun Yan, Li Zhang

“…As the most frequent and earliest type of psychotic phenomenon in Parkinson’s disease (PD), minor hallucination (MH) can occur before the onset of motor symptoms. This sensation may be an early predictor of severe psychotic and cognitive states and is often overlooked in clinics. …”
Get full text

Cerebral Reorganization in Subacute Stroke Survivors after Virtual Reality-Based Training: A Preliminary Study by Xiang Xiao, Qiang Lin, Wai-Leung Lo, Yu-Rong Mao, Xin-chong Shi, Ryan S. Cates, Shu-Feng Zhou, Dong-Feng Huang, Le Li

“…Increased activation in the primary sensorimotor cortex of the lesioned hemisphere and supplementary motor areas of both sides for the paretic foot (p<0.01) was observed postintervention. …”
Get full text

Bioinspired activation strategies for Peano-HASEL artificial muscle. by Zhaozhen Liu, Harrison McAleese, Andrew Weightman, Glen Cooper

“…This versatile ability is believed to be associated with muscle activation strategies, such as the number and position of activated motor units within the muscle, as well as the frequency, magnitude and shape of the activation signal. …”
Get full text

Association of plasma biomarkers of Alzheimer’s pathology and neurodegeneration with gait performance in older adults by Farwa Ali, Jeremy A. Syrjanen, Dan J. Figdore, Walter K. Kremers, Michelle M. Mielke, Clifford R. Jack, David S. Knopman, Prashanthi Vemuri, Jonathan Graff-Radford, B. Gwen Windham, Leland R. Barnard, Ronald C. Petersen, Alicia Algeciras-Schimnich

“…Conclusion Plasma biomarkers of neurodegeneration and Alzheimer’s Disease pathology are not only markers of cognitive decline but also indicate motor decline in the aging population.…”
Get full text

Numbness and Weakness Recovered at a Less Extent in Patients with Lumbar Disc Herniation after Percutaneous Endoscopic Lumbar Discectomy by Yuming Wang, Fuqiang Gao, Haibo Zou

“…Patients with lumbar disc herniation (LDH) may present with motor disorders and various sensory disorders, among which pain and numbness are the most common ones. …”
Get full text

Xenopus laevis neural stem progenitor cells exhibit a transient metabolic shift toward glycolysis during spinal cord regeneration by Paula G. Slater, Paula G. Slater, Miguel E. Domínguez-Romero, Guillermo Campos, Guillermo Campos, Vania Aravena, Vania Aravena, Javier Cavieres-Lepe, Verónica Eisner

“…Spinal cord injury (SCI) results in severe disruption of communication between the brain and body, causing motor, sensory, and autonomic dysfunctions. While SCI in mammals leads to permanent impairment due to limited regenerative capacity, certain non-mammalian species, such as Xenopus laevis larval stages, exhibit remarkable regenerative abilities. …”
Get full text

A randomized controlled interventional study for analgesic effects of intrathecal versus intravenous dexmedetomidine on subarachnoid anesthesia with hyperbaric bupivacaine by Manu Dadhwal, Anupama Gupta, Ajay Kurian

“…The duration of sensory and motor block was prolonged in groups B and C. The Visual analog scale scores were comparatively higher in group A than in groups B and C. …”
Get full text

A case of 49,XXXYY followed-up from infancy to adulthood with review of literature by Junko Kanno, Akinobu Miura, Sayaka Kawashima, Hirohito Shima, Dai Suzuki, Miki Kamimura, Ikuma Fujiwara, Masayuki Kamimura, Mitsugu Uematsu, Masataka Kudo, Atsuo Kikuchi

“…Subsequent examinations were conducted due to various symptoms, including delayed motor development, intellectual disability, facial dysmorphisms, forearm deformities, hip dysplasia, cryptorchidism, micropenis, primary hypogonadism, and essential tremor. …”
Get full text

Electromyographic Characteristics of a Single Motion Shoulder Exercise: A Pilot Study Investigating a Novel Shoulder Exercise by Michael J Henehan, Tamar Brand-Perez, Jeffrey C Peng, Masaaki Tsuruike

“…# Background Shoulder exercises focused on strengthening the rotator cuff and scapular stabilizing muscles as well as addressing scapular dyskinesis and motor control have been shown to improve rotator cuff function and decrease shoulder pain. …”
Get full text

A novel “lateral approach short axis in-plane” technique vs. conventional “short-axis out-of-plane approach” for ultrasound-guided internal jugular vein access: a prospective rando... by Michal Kalina, Patricia Vargová, Adéla Bubeníková, Roman Škulec, Vladimír Černý, David Astapenko

Get full text

High-Intensity Interval Training Improves Physical Function, Prevents Muscle Loss, and Modulates Macrophage-Mediated Inflammation in Skeletal Muscle of Cerebral Ischemic Mice by Lu Luo, Meixi Liu, Hongyu Xie, Yunhui Fan, Jingjun Zhang, Li Liu, Yun Li, Qiqi Zhang, Junfa Wu, Congyu Jiang, Yi Wu

“…HIIT was more beneficial than MOD for improvements in muscle strength, motor coordination, walking competency, and cardiorespiratory fitness. …”
Get full text

Integrated analysis of chromatin and transcriptomic profiling of the striatum after cerebral hypoperfusion in mice by Shijia Le, Fengyiyang Xu, Zhi Luo, Weihao Shi, Shuangshuang Lu, Zengyu Zhang, Zimin Guo, Wenshi Xu, Mingqi Yang, Tianyi Li, Xu Li, Kun Liang, Lei Zhu

“…This study investigated the molecular and epigenetic changes in the striatum, a brain region critical for motor function and cognition, following chronic hypoperfusion using a bilateral common carotid artery stenosis (BCAS) model in mice. …”
Get full text

Acupuncture as prophylaxis for chronic migraine: a protocol for a single-blinded, double-dummy randomised controlled trial by Claire Shuiqing Zhang, Bin Li, Lin Zeng, Lu Liu, Luo-peng Zhao, Kelun Wang, Jingxia Zhao, Linpeng Wang, Xianghong Jing

Get full text

Neurocognitive Functioning among Children with Sickle Cell Anemia Attending SCA Clinic at MNH, Dar es Salaam, Tanzania by Limi O. Matondo, Edward Kija, Karim P. Manji

“…Children with sickle cell anemia are at a higher risk of developing neurological sequelae like abnormal intellectual functioning, poor academic performance, abnormal fine motor functioning, and attentional deficits. There is a paucity of data about neurocognitive impairment among children with sickle cell anemia in Tanzania. …”
Get full text

Spina Bifida Occulta with Bilateral Spondylolysis at the Thoracolumbar Junction Presenting Cauda Equina Syndrome by Kentaro Mataki, Masao Koda, Yosuke Shibao, Hiroshi Kumagai, Katsuya Nagashima, Kousei Miura, Hiroshi Noguchi, Toru Funayama, Tetsuya Abe, Masashi Yamazaki

“…A 37-year-old man presented with a gait disorder as a result of bilateral motor weakness of the lower extremities. A plain radiograph showed local kyphosis at L1-2 as a result of severe degenerative change and wedging of the vertebral body at L1. …”
Get full text

Disease-Associated Dopamine Receptor D2 Variants Exhibit Functional Consequences Depending on Different Heterotrimeric G-Protein Subunit Combinations by Nele Niebrügge, Olga Trovato, Roman Praschberger, Andreas Lieb

“…DRs are essential for mediating various downstream signaling cascades and play a critical role in regulating the dopaminergic nigrostriatal pathway, which is involved in motor control. Recently, mutations in DRD2 (WT), p.Ile212Phe (I212F), and p.Met345Arg (M345R) have been associated with hyperkinetic movement disorders and shown to alter heterotrimeric G-protein complex signaling and β-arrestin recruitment. …”
Get full text

Exploring Machine Learning Classification of Movement Phases in Hemiparetic Stroke Patients: A Controlled EEG-tDCS Study by Rishishankar E. Suresh, M S Zobaer, Matthew J. Triano, Brian F. Saway, Parneet Grewal, Nathan C. Rowland

“…Background/Objectives: Noninvasive brain stimulation (NIBS) can boost motor recovery after a stroke. Certain movement phases are more responsive to NIBS, so a system that auto-detects these phases would optimize stimulation timing. …”
Get full text

A review of parameter settings for galvanic vestibular stimulation in clinical applications by Yishai Valter, Yishai Valter, Linda Vataksi, Aaron R. Allred, Jeffrey R. Hebert, Tad T. Brunyé, Tad T. Brunyé, Torin K. Clark, Jorge Serrador, Abhishek Datta, Abhishek Datta

“…The method has been tested for decades for both medical and non-medical applications and has demonstrated promise in treating a variety of disorders including peripheral vestibular conditions, central vestibular pathology due to neurodegenerative diseases, and post-stroke motor rehabilitation. As GVS continues to grow in popularity and applications, the field lacks clarity on appropriate stimulation parameters, despite their importance for safe and efficacious neuromodulation. …”
Get full text

Wearable Sensors Measure Ankle Joint Changes of Patients with Parkinson’s Disease before and after Acute Levodopa Challenge by Zhuang Wu, Xu Jiang, Min Zhong, Bo Shen, Jun Zhu, Yang Pan, Jingde Dong, Pingyi Xu, Wenbin Zhang, Li Zhang

“…The improvement in the sum of rigidity items (UPDRS motor subsection item 22) was also correlated with HS (rs = 0.389, P=0.037) and 3-PF (rs = 0.373, P=0.046) improvement rates. …”
Get full text