Development of Curcumin Encapsulated Liposomes in Chlorhexidine-Loaded Organogel Using Ternary Phase Systems for Treatment of Omphalitis in Infants by Ibilola Mary Cardoso-Daodu, Margaret Okonawan Ilomuanya

“…Infections in infants, after childbirth, remain a leading cause of neonatal morbidity and mortality, globally. A soaring percentage of these infections arise from bacterial colonization of the umbilicus. …”
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Drosophila Cul3 contributes to Diap2-mediated innate immune signaling for antimicrobial defense by Fanrui Kong, Zixuan Wang, Chuchu Zhang, Yihua Xiao, Muhammad Abdul Rehman Saeed, Weini Li, Akira Goto, Qingshuang Cai, Shanming Ji

“…We show that silencing of Cul3 leads to a decreased induction of antimicrobial peptides and high mortality in adult flies after bacterial infection. …”
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Understanding biofilm--phage interactions in cystic fibrosis patients using mathematical frameworks by Emerenini Blessing O., Hartung Doris, Reyes Grimaldo Ricardo N. G., Canner Claire, Williams Maya, Agyingi Ephraim, Osgood Robert

“…Our results show that, by increasing the phage mortality rate, the biofilm growth can be balanced, which makes it more vulnerable to antibiotics. …”
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Addressing the rising colorectal cancer burden in the older adult: examining modifiable risk and protective factors for comprehensive prevention strategies by Ke‐Jie He, Zhejun Liu, Guoyu Gong

“…Countries like Uruguay, Monaco, Croatia, Hungary, and Poland exhibited higher mortality and disability-adjusted life-year (DALY) rates, while regions like Bangladesh, Nepal, and much of Africa had relatively lower disease burden. …”
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Outcomes and physiologic responses associated with ketamine administration after traumatic brain injury in the United States and Canada: a retrospective analysis by Austin J. Peters, Saad A. Khan, Seiji Koike, Susan Rowell, Martin Schreiber

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Computer-Aided Construction and Evaluation of Poly-L-Lysine/Hyodeoxycholic Acid Nanoparticles for Hemorrhage and Infection Therapy by Qin Qin, Wenxing Wu, Ling Che, Xing Zhou, Diedie Wu, Xiaohui Li, Yumin Yang, Jie Lou

“…<b>Background:</b> Traumatic hemorrhage and infection are major causes of mortality in wounds caused by battlefield injuries, hospital procedures, and traffic accidents. …”
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Optimization, Characterization, and Antibacterial Activity of Copper Nanoparticles Synthesized Using Senna didymobotrya Root Extract by Bernard Otieno Sadia, Jackson Kiplagat Cherutoi, Cleophas Mecha Achisa

“…The economic burden and high mortality associated with multidrug-resistant bacteria is a major public health concern. …”
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Multidrug resistance of Pseudomonas aeruginosa: do virulence properties impact on resistance patterns? by Poulomi Saha, Rubaiya Binte Kabir, Chowdhury Rafiqul Ahsan, Mahmuda Yasmin

“…IntroductionPatients with nosocomial infections are at risk of multidrug-resistant (MDR) Pseudomonas aeruginosa since these bacteria slow down the entire treatment process, increasing the morbidity and mortality of patients staying in hospital. The purpose of the research was to assess the simultaneous presence of multidrug resistance and virulence factors among nosocomial strains of P. aeruginosa to evaluate significant association among them.MethodsOne hundred and eight clinical isolates of P. aeruginosa were found in a variety of samples taken from patients having nosocomial infection, including wound swabs, pus, sputum, tracheal aspirate, and urine. …”
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DNA vaccines as promising immuno-therapeutics against cancer: a new insight by Alireza Shariati, Arya Khezrpour, Fatemeh Shariati, Hamed Afkhami, Hamed Afkhami, Hamed Afkhami, Aref Yarahmadi, Sajad Alavimanesh, Sajad Alavimanesh, Sina Kamrani, Mohammad Hossein Modarressi, Pouria Khani

“…Cancer is one of the leading causes of mortality around the world and most of our conventional treatments are not efficient enough to combat this deadly disease. …”
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Exploring the anti-metastatic potential of sunitinib and novel analogs in colorectal cancer: insights into HIF-1α mediated metastasis by Fatemeh B. Rassouli, Maryam M. Matin, Maryam M. Matin, Farzin Hadizadeh, Farzin Hadizadeh, Masoud Nejabat, Hossein Allahverdizadeh, Hamidreza Jamali, Shahin Gharedaghi, Halimeh Hassanzadeh

“…IntroductionColorectal cancer (CRC) is a prevalent malignancy worldwide with high mortality rate. Metastasis, the primary cause of cancer-related deaths, is attributed to various factors including tumor hypoxia. …”
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The Impact of Nutritional Status and Tumor-Infiltrating Lymphocytes (CD4+ and CD8+) on Chemotherapy Response in Colorectal Cancer Patients by Lukman K, Septianto R, Rudiman R, Ruchimat T, Sribudiani Y, Nugraha P, Primastari E, Budiman D

“…The immune system plays a vital role in fighting cancer, and certain immune cells, called tumor-infiltrating lymphocytes (TILs), may help the body combat colorectal cancer. Specifically, we looked at two types of these immune cells, CD4+ and CD8+, and their connection to patients’ nutritional health during chemotherapy. …”
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mRNA-LNP vaccines combined with tPA signal sequence elicit strong protective immunity against Klebsiella pneumoniae by Ting Huang, Siyou Che, Zheng Lv, Danrui Hao, Runyu Wang, Qinxuan Yi, Ling Mei, Yang Yuan, Hang Zou, Yidong Guo, Xinrong Wang, Yiwen Chu, Kelei Zhao

“…Despite the widespread anti-microbial resistance and the high mortality rate, currently, no clinically vaccine is approved for battling K. pneumoniae. …”
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Biogenic silver nanoparticles produced by Trichoderma reesei inhibit SARS-CoV-2 infection, reduce lung viral load and ameliorate acute pulmonary inflammation by Marcus V.M.V. Amaral, Cláudia B. Carraro, Amanda C.C. Antoniêto, Mariana N. Costa, Thais F.C. Fraga-Silva, Ualter G. Cipriano, Rodrigo P.F. Abuná, Tamara S. Rodrigues, Ronaldo B. Martins, Andreia M. Luzenti, Glaucia R. Caruso, Priscyla D. Marcato, Vania L.D. Bonato, Dario S. Zamboni, Bergman M. Ribeiro, Sônia N. Báo, Joao S. da Silva, Flávio P. Veras, Roberto N. Silva

“…Nonetheless, our findings offer promising insights into the development of novel therapeutic strategies for combating COVID-19 and reducing its associated morbidity and mortality.…”
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Isolation of probiotics bacterium from coral reef for controlling vibriosis in tiger shrimp (Penaeus monodon) larvae by Ade Dwi Sasanti, . Widanarni, . Sukenda

“… Pathogenic Vibrio, especially luminous Vibrio harveyi, could cause mass mortality in tiger shrimp culture. One of the technique to work against luminous Vibrio is, using probiotic bacteria to inhibit the luminous Vibrio growth. …”
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Data recording and use of data tools for pig health management: perspectives of stakeholders in pig farming by Xiao Zhou, Andrea Knörr, Beatriz Garcia Morante, Beatriz Garcia Morante, Beatriz Garcia Morante, Carla Correia-Gomes, Lucia Dieste Pérez, Joaquim Segalés, Joaquim Segalés, Joaquim Segalés, Marina Sibila, Marina Sibila, Marina Sibila, Carles Vilalta, Carles Vilalta, Carles Vilalta, Alison Burrell, Tijs Tobias, Michael Siegrist, Angela Bearth

“…IntroductionData-driven strategies might combat the spreading of infectious pig disease and improve the early detection of potential pig health problems. …”
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Twin to Twin Transfusion Syndrom by Yusrawati ., Rika Effendy

“…<p>Abstrak<br />Peningkatan mortalitas pada kembar monokorion disebabkan oleh adanya anastomosis vaskuler pada plasenta yang menyebabkan Twin to Twin Transfussion syndrome.Berikut laporan kasus yang ditangani di RS. …”
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CoviWall, a whole-virion-inactivated B.1.617.2 vaccine candidate, induces potent humoral and Th1 cell response in mice and protects against B.1.617.2 strain challenge in Syrian ham... by Jyotsna Dandotiya, Neeta Adhikari, Manas Ranjan Tripathy, Manas Ranjan Tripathy, Kamini Jakhar, Sudipta Sonar, Dibya Ranjan Pati, Vibhu Kanchan, Varsha S. Prasad, Jitendra Kumar, Nitesh K. Senapati, Arti Bharmoria, Neeraj Rani, Monika Lakhanpal, CS. Patil, Nishan Singh, Lovely Khan, Lavit Jambu, Naveen K. Jain, Syed Khalid Ali, Priyanka Priyadarsiny, Amulya K. Panda, Rajesh Jain, Shailendra Mani, Sweety Samal, Amit Awasthi, Amit Awasthi, Zaigham Abbas Rizvi, Zaigham Abbas Rizvi

“…Rapid development of coronavirus disease 2019 (COVID-19) vaccines and antiviral drugs have significantly reduced morbidity and mortality worldwide. Although most of the vaccines were developed initially with the ancestral Wuhan antigen, here, we report the development and immunological efficacy of a whole-virion–inactivated vaccine candidate (CoviWall) to combat the deadly B.1.617.2 (Delta strain) infection. …”
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The potential of bacteriophage for controlling Vibrio parahaemolyticus as in-vitro by Bagus Ansani Takwin, Dinamella Wahjuningrum, Widanarni Widanarni, Hasan Nasrullah

“… Vibrio parahaemolyticus infection is a major threat to Pacific white shrimp aquaculture, causing significant shrimp mortality. Bacteriophages (phages) provide a promising antibiotic alternative due to their specificity towards specific bacteria. …”
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Burden of bacterial antimicrobial resistance among hospitalised patients in Spain: findings from three nationwide prospective studiesResearch in context by Germán Peñalva, Rafael Cantón, María Teresa Pérez-Rodríguez, Juan José González-López, Jesús Rodríguez-Baño, Ester del Barrio-Tofiño, Cristina Kirkegaard-Biosca, Isabel Sánchez-Romero, Andrea Gutiérrez-Villanueva, Teresa Marrodán-Ciordia, José Manuel Guerra-Laso, Cristóbal del Rosario-Quintana, Laura Suárez-Hormiga, Jordi Cámara, Mireia Puig-Asensio, Eva Heredero, María Antonia Sepúlveda, Juan Carlos Rodríguez-Díaz, Esperanza Merino, Emilia Cercenado, Sofia de la Villa, María Siller, Francisco Arnaiz, Cristina Seral, José Antonio Lepe, José Miguel Cisneros, José Ramón Paño-Pardo

“…Interpretation: The burden of disease caused by MDRO infections among hospitalised patients in Spain is very high and remains stable over the study period. National actions to combat bacterial resistance need to be intensified. …”
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Timing of Antiretroviral Therapy for HIV in the Setting of TB Treatment by Damani A. Piggott, Petros C. Karakousis

“…The convergent human immunodeficiency virus (HIV) and tuberculosis (TB) pandemics continue to collectively exact significant morbidity and mortality worldwide. Highly active antiretroviral therapy (HAART) has been a critical component in combating the scourge of these two conditions as both a preemptive and therapeutic modality. …”
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