New frontiers in CRISPR: Addressing antimicrobial resistance with Cas9, Cas12, Cas13, and Cas14 by Ahmed S.A. Ali Agha, Ali Al-Samydai, Talal Aburjai

“…Background: The issue of antimicrobial resistance (AMR) poses a major challenge to global health, evidenced by alarming mortality predictions and the diminishing efficiency of conventional antimicrobial drugs. …”
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Comprehensive Update on Rabies: A Neglected Zoonotic Disease of Public Health Concern by Kavitha Guladahalli Manjunatha, Chethana Chandrahasa, Sadanand Dangari Akshay, Akhila Dharnappa Sannejal, Rajeshwari Vittal, Govindaiah Kavitha, Khang Wen Goh, Shrikrishna Isloor, Devananda Devegowda

“…India carries the greatest share of worldwide mortalities resulting from rabies transmitted by dogs to humans. …”
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Adenine-induced animal model of chronic kidney disease: current applications and future perspectives by Qiao Yang, Songya Su, Nan Luo, Gang Cao

“…Chronic kidney disease (CKD) with high morbidity and mortality all over the world is characterized by decreased kidney function, a condition which can result from numerous risk factors, including diabetes, hypertension and obesity. …”
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Review of Current Strategies to Address Micronutrient Deficiencies (MNDs) in Ghana: A Scoping Review by Jolene Mateko Azagba-Nyako, Charles Tortoe, Paa Toah Akonor, Alice Padi, Jackline Boateng, Richard Otwey

“…To achieve the Sustainable Development Goals by 2030, low-income countries like Ghana will require strategizing towards sustainable reduction in micronutrient deficiency (MND) diseases and MND-related morbidity and mortality. A scoping review was conducted to identify the policy framework around MND intervention, the actors implementing MND-related strategies and documented evidence on which strategies worked across implementation stakeholders. …”
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Nutritional and lifestyle intervention strategies for metabolic syndrome in Southeast Asia: A scoping review of recent evidence. by Sze Mun Thor, Jun Wern Yau, Amutha Ramadas

“…To combat its increasing prevalence in Southeast Asia, numerous intervention programs have been implemented. …”
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In vitro triazophos suppresses innate and cell-mediated immune responses of lymphoid organs in snakehead fish, Channa punctatus by Rakesh Kumar Chandra, Ajay Kumar Bhardwaj, Neha Gupta, Devendra Kumar Patel, Manish Kumar Tripathi

“…The findings of this study will aid in developing appropriate measures to combat freshwater ecotoxicity.…”
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Jusvinza treatment resolution in confirmed COVID-19 patients. Santiago de Cuba, 2021 by Sandra Caridad Laurencio Vallina, Martha María Arias Carbonell, Leonardo Ramos Hechavarría, Dayami Lescay Balanquet, Roger Pina Núñez

“…In this context, the Cuban Biotechnology and Pharmaceutical Industries Group (BioCubaFarma) created therapeutic alternatives to combat COVID-19, including the use of Jusvinza, which is part of the protocol used in the country. …”
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The semi-wild mariculture of Caribbean King Crab (Maguimithrax spinosissimus) for coral reef restoration by Samantha Glover, Mark J. Butler, IV

“…For example, the in situ and ex situ rearing of corals for coral reef restoration is now implemented worldwide, but its success is limited by the lack of reef herbivores to combat the phase shift from coral-to-macroalgae-dominance on reefs, especially in the Caribbean. …”
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An efficient artificial neural network-based optimization techniques for the early prediction of coronary heart disease: comprehensive analysis by Subhash Mondal, Ranjan Maity, Amitava Nag

“…Abstract Coronary heart disease (CHD) is the world’s leading cause of death, contributing to a high mortality rate. This emphasizes the requirement for an advanced decision support system in order to evaluate the risk of CHD. …”
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Phage-Derived Endolysins Against Resistant Staphylococcus spp.: A Review of Features, Antibacterial Activities, and Recent Applications by Mina Golban, Javad Charostad, Hossein Kazemian, Hamid Heidari

“…In recent years, there has been growing interest in using endolysins to combat bacterial infections. These enzymes, which are also referred to as lysins, are a unique class of hydrolytic enzymes synthesized by double-stranded DNA bacteriophages. …”
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A novel strategy for eradication of staphylococcal biofilms using blood clots by Kayla E. Grooters, Sheridan L. Hayes, David M. Richter, Jennifer C. Ku, Robert Sawyer, Yong Li

“…IntroductionInfections with coagulase negative staphylococcal species (CoNS) are a major cause of mortality and morbidity in joint and heart valve replacement procedures, largely due to biofilm formation. …”
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The role of PM2.5 exposure in lung cancer: mechanisms, genetic factors, and clinical implications by Chi-Yuan Chen, Kuo-Yen Huang, Chin-Chuan Chen, Ya-Hsuan Chang, Hsin-Jung Li, Tong-Hong Wang, Pan-Chyr Yang

“…While smoking is the primary risk factor, an increasing number of cases occur in nonsmokers, with lung cancer in nonsmokers (LCNS) now recognized as the fifth leading cause of cancer mortality worldwide. Recent evidence identifies air pollution, particularly fine particulate matter (PM2.5), as a significant risk factor in LCNS. …”
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Nano-biopesticide formulation comprising of silver nanoparticles anchored to Ocimum sanctum: a sustainable approach to pest control in jute farming by Avirup Ghosh, Dipanwita Majumdar, Himani Biswas, Anupam Chowdhury, Sanjoy Podder

“…The best eco-friendly methods to combat these jute pests involve administration of nano-biopesticides, as a successful alternative to the toxic chemicals. …”
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Improving Accuracy of Malaria Diagnosis in Underserved Rural and Remote Endemic Areas of Sub-Saharan Africa: A Call to Develop Multiplexing Rapid Diagnostic Tests by Rasheed O. Makanjuola, Andrew W. Taylor-Robinson

“…This is especially relevant to low-income countries in tropical and subtropical regions of the world where high rates of malaria-related morbidity and mortality are recorded. As a means to combat this major global public health threat, rapid and effective diagnosis remains the frontline action to initiate a timely and appropriate medical intervention. …”
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Integrating mandatory occupational health practice and workplace health promotion programs to reduce the high burden of work-related diseases by Francesco CHIRICO, Angelo SACCO, Nicola MAGNAVITA

“…Sedentary occupations and metabolic syndrome (MetS) are associated with an increased risk of type 2 diabetes mellitus (T2DM) and coronary heart disease, contributing to elevated mortality rates from CVDs. Occupational risk assessment and management are crucial for developing tailored plans to control and mitigate workplace hazards that lead to occupational and work-related diseases. …”
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Methicillin-Resistant Staphylococcus aureus: Docking-Based Virtual Screening and Molecular Dynamics Simulations to Identify Potential Penicillin-Binding Protein 2a Inhibitors from... by Motahareh Masumi, Fatemeh Noormohammadi, Fatemeh Kianisaba, Fatemeh Nouri, Mohammad Taheri, Amir Taherkhani

“…The binding affinity of SauPBP2a to beta-lactam antibiotics is low, and thus, it is necessary to discover new effective SauPBP2a inhibitors to combat mortality and morbidity in patients affected by MRSA. …”
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The global, regional, and national burden of oral cancer, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 by Junmeng Wu, He Chen, Yingjun Liu, Ruotong Yang, Na An

“…Policymakers are urged to implement screening programs and public health education to combat the disease.…”
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Effects of runoff harvesting through semi-circular bund on some soil characteristics by M. Heshmati, M. Gheitury, M. Hosseini

“…In this study, to investigate the effects of runoff harvesting on soil properties in the semiarid forest, runoff harvesting through semi-circular bund was considered as a method to conserve soil and thereby combat tree mortality. In order to evaluate this hypothesis, runoff was harvested through the semi-circular bund affecting soil quality and moisture storage. …”
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Genotype Diversity of Newcastle Disease Virus in Nigeria: Disease Control Challenges and Future Outlook by Muhammad Bashir Bello, Khatijah Mohd Yusoff, Aini Ideris, Mohd Hair-Bejo, Ben P. H. Peeters, Abdurrahman Hassan Jibril, Farouk Muhammad Tambuwal, Abdul Rahman Omar

“…The disease is associated with severe respiratory, gastrointestinal, and neurological lesions in chicken leading to high mortality and several other production related losses. …”
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In Vivo Antimalarial Activity of 80% Methanol and Aqueous Bark Extracts of Terminalia brownii Fresen. (Combretaceae) against Plasmodium berghei in Mice by Hana Biruk, Biruk Sentayehu, Yonatan Alebachew, Wondmagegn Tamiru, Abebe Ejigu, Solomon Assefa

“…Evergrowing resistance towards the currently available antimalarial drugs is a challenge to combat malaria. Medicinal plants are a promising source of new drugs to tackle this problem. …”
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