Real‐world clinical diagnostics of heart failure patients with reduced or preserved ejection fraction by Jenni Huusko, Timo Purmonen, Iiro Toppila, Mariann Lassenius, Heikki Ukkonen

“…HFpEF {4580 [inter‐quartile range (IQR): 2065–9765] vs. 2900 [2065–9765] ng/L, P < 0.001}. Baseline co‐morbidities differed between HFpEF and HFrEF groups. …”
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Identifikasi Nyamuk Anopheles Sebagai Vektor Malaria dari Survei Larva di Kenagarian Sungai Pinang Kecamatan Koto XI Tarusan Kabupaten Pesisir Selatan by Suci Lestari, Adrial Adrial, Rosfita Rasyid

“…</p><p><strong>Kata kunci: </strong>nyamuk anopheles, larva anopheles, tempat perindukan, kepadatan larva</p><p> </p><p><strong><em>Abstract</em></strong></p><p>Malaria is a global health problem that causes high morbidity and mortality, especially in the tropics and subtropics areas. …”
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Risk Factors and Pharmacological Interventions Impacting Cerebrovascular Ischemic Events in Giant Cell Arteritis: A Narrative Review by Muhammad Osama Siddiqui, Mohammad Ali Syed, Ayaan Ahmed Qureshi, Mustafa Hussain Imam, Jatin Motwani, Verkha Kumari, Arooba Siddiqui, Noor Ul Ain, Mohammed Hammad Jaber

“…Identifying these risk factors is crucial for reducing morbidity and mortality, equipping physicians to better assess and mitigate the risk of CIE in GCA patients.…”
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Prevalence, cessation, and geographical variation of smoking among middle-aged and elderly adults in China: A population-based study by Qingjia Zeng, Chongyang Zhang, Feiyu Su, Yanli Wan, Wen-jun Tu, Hongpu Hu

“…Introduction Smoking significantly burdens human health, contributing to an increasing incidence of mortality and morbidity. This study aims to explore the prevalence of smoking, cessation, and the association between various risk factors and smoking intensity measured in pack-years among Chinese adults. …”
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Development of Cephradine-Loaded Gelatin/Polyvinyl Alcohol Electrospun Nanofibers for Effective Diabetic Wound Healing: In-Vitro and In-Vivo Assessments by Anam Razzaq, Zaheer Ullah Khan, Aasim Saeed, Kiramat Ali Shah, Naveed Ullah Khan, Bouzid Menaa, Haroon Iqbal, Farid Menaa

“…Diabetic wound infections caused by conventional antibiotic-resistant <i>Staphylococcus aureus</i> strains are fast emerging, leading to life-threatening situations (e.g., high costs, morbidity, and mortality) associated with delayed healing and chronic inflammation. …”
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Intra-articular Glenoid Fracture Managed by Arthroscopic Fixation and Open Reduction and Internal Fixation Techniques: An Analytical Study by Prahalad K Singhi, Sivakumar Raju, Chidambaram Muthu, Gopi Kumarasamy, Vinoth Thangamani, Muthukishore Marichamy

“…Conclusion: Intra-articular glenoid fractures are uncommon injuries but can end up in severe morbidity if neglected or not aptly treated. Anatomical restoration of the articular surface is the goal in management of intra-articular glenoid fractures. …”
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Dyslipidemia and metabolic syndrome in childhood-onset systemic lupus erythematosus: is it time to screen? by Sirin Nuntasri, Sirirat Charuvanij, Kraisoon Lomjansook, Puthita Saengpanit, Kwanjai Chotipanang, Maynart Sukharomana

“…Abstract Background Childhood-onset systemic lupus erythematosus (cSLE) is associated with significant morbidity and mortality. Dyslipidemia and metabolic syndrome are recognized risk factors for premature atherosclerosis. …”
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Eating "rubbish"? Exploring the herbal secrets of "Laji-He," a traditional herbal rice snack from southern China by Renchuan Hu, Qianyun Wang, Zhongxin Duan, Yunan Hu, Kedao Lai, Xiaohui Cai, Ya Peng, Binsheng Luo

“…The most commonly used plants, such as Paederia foetida, Piper sarmentosum, Houttuynia cordata, Centella asiatica, and Morus alba, were primarily utilized for their heat-clearing, detoxifying, and wind-dampness expelling properties. …”
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Three-year course of clinical high-risk symptoms for psychosis in the community: a latent class analysis by C. Michel, N. Osman, G. Rinaldi, B. G. Schimmelmann, J. Kindler, F. Schultze-Lutter

“…Classes 1 and 2 included more participants with functional impairment and psychiatric morbidity. Class 3 participants had a low probability of having functional deficits or mental disorders at both time points, suggesting that Class 3 was the healthiest group and that their mental health and functioning remained stable throughout the study period. …”
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Assessment of upper respiratory and gut bacterial microbiomes during COVID-19 infection in adults: potential aerodigestive transmission by Hafez Al-Momani, Andrew Nelson, Hadeel Al Balawi, Dua’a Al Balawi, Iman Aolymat, Ashraf I. Khasawneh, Hala Tabl, Ayman Alsheikh, AbdelRahman M. Zueter, Jeffrey Pearson, Christopher Ward

“…Abstract SARS-CoV-2 is the viral pathogen responsible for COVID-19. Although morbidity and mortality frequently occur as a result of lung disease, the gastrointestinal (GI) tract is recognized as a primary location for SARS-CoV-2. …”
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Effect of zinc added to a daily small-quantity lipid-based nutrient supplement on diarrhoea, malaria, fever and respiratory infections in young children in rural Burkina Faso: a cl... by Elizabeth Yakes Jimenez, Sonja Y Hess, Souheila Abbeddou, Kenneth H Brown, Jean-Bosco Ouedraogo, Jérôme W Somé, Zinéwendé P Ouédraogo, Rosemonde M Guissou, Stephen A Vosti

“…Participants were visited weekly in their homes for morbidity surveillance for 9 months, and those with uncomplicated diarrhoea and malaria received treatment from the study field workers in the community.Main outcomes Incidence and longitudinal prevalence of diarrhoea, malaria, fever, and lower and upper RTI by intervention group.Results The incidence of diarrhoea, malaria and fever was 1.10 (±1.03 SD), 0.61 (±0.66 SD) and 1.49 (±1.12 SD) episodes per 100 child-days at risk, respectively, and did not differ by intervention group (p=0.589, p=0.856 and p=0.830, respectively). …”
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Health checks for autistic adults: study protocol for a cluster randomised controlled trial by Jeremy R. Parr, Helen Taylor, Colin Wilson, Clare Scarlett, Sarah Al-Asmori, Carole Buckley, Sally-Ann Cooper, Cristina Fernandez-Garcia, Tracy Finch, Rhianna Lees, Nicholas Lennox, Hannah Merrick, Sebastian Moss, Christina Nicolaidis, Malcolm Osbourne, Dora M. Raymaker, Tomos Robinson, Anna Urbanowicz, James M. S. Wason, Barry Ingham

“…These factors may lead to increased and earlier morbidity and lower average life expectancy for autistic people. …”
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Evaluation of Inflammatory Markers and Clinical Outcomes in COVID-19 Patients with Concurrent <i>Clostridioides difficile</i> Infection: A Comparative Cohort Analysis by Flavia Ignuta, Adrian Vlad, Teodor Cerbulescu, Stana Loredana, Felix Bratosin, Ovidiu Rosca, Lavinia Stelea, Daciana Nistor

“…Background and Objectives: Co-infection with <i>Clostridioides difficile</i> (<i>C. difficile</i>) in COVID-19 patients has emerged as a clinical challenge associated with increased morbidity and mortality. While both infections elicit systemic inflammation, the interplay between inflammatory markers, disease severity, and outcomes in patients with COVID-19 and concurrent <i>C. difficile</i> infection remains poorly characterized. …”
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Ligilactobacillus salivarius LZZAY01 accelerated autophagy and apoptosis in colon cancer cells and improved gut microbiota in CAC mice by Wenhong Yang, Tao Li, Shixiang An, Rong Chen, Yuxin Zhao, Jiaxian Cui, Mingyu Zhang, Jingkun Lu, Yunpeng Tian, Lili Bao, Pengwei Zhao

“…ABSTRACT Colorectal cancer (CRC) is one of the malignant tumors globally, with high morbidity and mortality rates. The mainstay treatment of CRC includes surgery, radiotherapy, and chemotherapy. …”
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Exploring the composition of placental microbiome and its potential origin in preterm birth by Marwa Saadaoui, Mohamed Nadhir Djekidel, Selvasankar Murugesan, Manoj Kumar, Duaa Elhag, Parul Singh, Basirudeen Syed Ahamed Kabeer, Basirudeen Syed Ahamed Kabeer, Alexandra Katharina Marr, Tomoshige Kino, Tobias Brummaier, Rose McGready, Rose McGready, François Nosten, François Nosten, Damien Chaussabel, Annalisa Terranegra, Souhaila Al Khodor

“…Additionally, it’s unclear whether the placental microbiome differs between healthy pregnancies and those with complications like preterm birth (PTB), which remains a leading cause of neonatal morbidity and mortality worldwide.MethodsIn this study, we performed 16S rRNA gene sequencing to investigate the composition of the oral and placental microbiome in samples collected from 18 women who experienced PTB and 36 matched controls who delivered at term (TB), all of whom were part of the Molecular Signature in Pregnancy (MSP) study. …”
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Clinical implication of NT-proBNP to predict mortality in patients with acute type A aortic dissection: a retrospective cohort study by Rui Zhang, Hao Wang, Chenxi Song, Rui Fu, Kefei Dou, Shuai Liu, Qianqian Liu, Xiaohui Bian, Weida Liu, Chengang Zhu, Jingjing Gao, Sheng Yuan, Xinming Cui, Sijia Qin, Yumeng Li

“…Objectives Acute type A aortic dissection is a life-threatening cardiovascular disease commonly seen in emergency department, resulting in substantial mortality and morbidity. We aimed to investigate the prognostic value of N-terminal pro-B type natriuretic peptide (NT-proBNP) among this critically ill population.Design The design of this study was a retrospective cohort study.Setting The study population was recruited in the Emergency Department of Fuwai hospital in China from 2018 to 2020.Participants We consecutively enrolled 829 patients with acute type A aortic dissection and measurable baseline NT-proBNP.Primary outcome The primary endpoint was 1-year all-cause death.Results Based on tertiles of NT-proBNP (pg/mL), patients were stratified into low (≤150.3, n=276), intermediate (150.3–667.6, n=277) and high (&gt;667.6, n=276) NT-proBNP groups. …”
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Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants by Gajalakshmi Ramanathan, Yuqi Zhao, Rajat Gupta, Siri Langmo, May Bhetraratana, Fen Yin, Will Driscoll, Jerry Ricks, Allen Louie, James A. Stewart, Timothy R. Gould, Timothy V. Larson, Joel Kaufman, Michael E. Rosenfeld, Xia Yang, Jesus A. Araujo

“…Abstract Background Exposure to air pollution is associated with worldwide morbidity and mortality. Diesel exhaust (DE) emissions are important contributors which induce vascular inflammation and metabolic disturbances by unknown mechanisms. …”
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Prevalence of Salmonella and Shigella species and their multidrug resistance patterns among pediatric populations in Ethiopia: a systematic review and meta-analysis by Mihret Tilahun, Melaku Ashagrie Belete, Alemu Gedefie, Habtu Debash, Ermiyas Alemayehu, Daniel Gebretsadik Weldehana, Hussein Ebrahim, Ousman Mohammed, Bruktawit Eshetu, Saba Gebremichael Tekele, Zewudu Mulatie, Agumas Shibabaw

“…They are pathogenic microbes that cause significant diarrheal morbidity and mortality in under five children in resource limited countries. …”
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Does high body mass index increase the risk of shoulder instability surgery? The LUXE prospective cohort study on 227 recurrent anterior shoulder instability by Vincent Roy, MD, MSc, Claire Bastard, MD, MSc, Emilie Sandman, MD, MSc, FRCSC, Alexis Rousseau-Saine, MD, FRCSC, Marie-Lyne Nault, MD, PhD, FRCSC, Dominique M. Rouleau, MD, MSc, FRCSC

“…Background: The aim of this study was to determine whether body mass index (BMI) plays a role in overall morbidity following shoulder instability surgery and whether some surgical techniques are BMI-sensitive. …”
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Determination of HLA Tissue Type According to the Etiology of Patients with Chronic Renal Failure by Burcu KARAKUS TURAN, Fahri UCAR, Vural Taner YILMAZ, Yahya KILINC, Sule DARBAŞ ARAS, Huseyin KOCAK, Nurten SAYIN EKINCI, Bulent AYDINLI, Habibe Sema ARSLAN

“…Conclusions: Since CKD shows serious morbidity and mortality, this comprehensive study of HLA subgroups gave an explanatory idea about which alleles associated with the disease in terms of susceptibility and protection.…”
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