Classification of Wheezing Children in Rural Bangladesh by Intensity of Ascaris Infection, Total and Specific IgE Levels, History of Pneumonia, and Other Risk Factors by Haruko Takeuchi, Md Alfazal Khan, Khalequz Zaman, Sayaka Takanashi, S. M. Tafsir Hasan, Mohammad Yunus, Tsutomu Iwata

“…Ascaris lumbricoides is the most common soil-transmitted helminth and infects 447 million people in impoverished areas worldwide. It causes serious morbidity including wheezing and influences various aspects of human immunity, such as type 2 innate lymphoid cells, regulatory T cell function, and acquired immunity. …”
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Pulmonary Densitovolumetry Using Computed Tomography in Patients with Nontuberculous Mycobacteria: Correlation with Pulmonary Function Tests by Patricia Gomes Cytrangulo De Marca, Telma Goldenberg, Fernanda Carvalho Queiroz Mello, Alysson Roncally Silva Carvalho, Alan Ranieri Medeiros Guimarães, Roberto Mogami, Agnaldo José Lopes

“…Since nontuberculous mycobacterial pulmonary disease (NTM-PD) is a condition with increasing morbidity, a more detailed knowledge of radiological aspects and pulmonary function plays a relevant role in the diagnosis and appropriate therapeutic management of these patients. …”
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Single-cell multiomics reveal divergent effects of DNMT3A- and TET2-mutant clonal hematopoiesis in inflammatory response by Wazim Mohammed Ismail, Jenna A. Fernandez, Moritz Binder, Terra L. Lasho, Minsuk Kim, Susan M. Geyer, Amelia Mazzone, Christy M. Finke, Abhishek A. Mangaonkar, Jeong-Heon Lee, Liguo Wang, Kwan Hyun Kim, Vernadette A. Simon, Fariborz Rakhshan Rohakthar, Amik Munankarmy, Seul Kee Byeon, Susan M. Schwager, Jonathan J. Harrington, Melissa R. Snyder, Keith D. Robertson, Akhilesh Pandey, Eric D. Wieben, Nicholas Chia, Alexandre Gaspar-Maia, Mrinal M. Patnaik

“…Here, we make use of a natural inflammatory response occurring during coronavirus disease 2019 (COVID-19), to understand the association of these mutations with inflammatory morbidity (acute respiratory distress syndrome [ARDS]) and mortality. …”
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Impact of quality of life on overall work productivity impairment and activity impairment of patients with systemic lupus erythematosus: the PEONY study by Yoshiya Tanaka, Shintaro Hirata, Shingo Nakayamada, Yusuke Miyazaki, Kazuyoshi Saito, Kunihiro Yamaoka, Shigeru Iwata, Yoshiyuki Yamaguchi, Keisuke Nakatsuka, Shunpei Kosaka, Katsuhide Kusaka, Toshiki Yabe-Wada, Masakazu Fujiwara, Yoshifumi Arita, Mitsuru Hoshino, Naoko Ozaki

“…Other objectives were to investigate the relationship between overall work productivity impairment or activity impairment and other PRO or disease activity measures.Results The analysis set included 205 patients; 93.2% were female, mean (SD) age at index date was 52.5 (14.7) years, mean (SD) duration of morbidity was 167.2 (125.2) months and 164 were in LLDAS. …”
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Calprotectin and Calgranulin C as Biomarkers of Pancreatic Tumors: Baseline Levels and Level Changes after Surgery by Michal Holub, Eva Bartáková, Alžběta Stráníková, Eva Koblihová, Simona Arientová, Marie Blahutová, Jan Máca, Miroslav Ryska

“…Pancreatic tumors and their surgical resection are associated with significant morbidity and mortality, and the biomarkers currently used for these conditions have limited sensitivity and specificity. …”
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Gender inequalities in prescribing and initiation patterns of guideline-recommended drugs after acute myocardial infarction by Irene López-Ferreruela, Sara Malo, Blanca Obón-Azuara, María José Rabanaque, Adriana Gamba, Sara Castel-Feced, Isabel Aguilar-Palacio

“…The proportion of subjects initiating treatment was similar in both genders. Overall, age and morbidity burden were the main contributors to differences in the prescribing patterns. …”
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Angioembolization performed by trauma surgeons for trauma patients: is it feasible in Korea? A retrospective study by Soonseong Kwon, Kyounghwan Kim, Soon Tak Jeong, Joongsuck Kim, Kwanghee Yeo, Ohsang Kwon, Sung Jin Park, Jihun Gwak, Wu Seong Kang

“…Results No significant differences were found between the interventional radiologists and the trauma surgeon in terms of re-embolization due to rebleeding, surgery due to rebleeding, or the overall failure rate of the first angioembolization. Mortality and morbidity rates were also similar between the two groups. …”
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Efforts to strengthen anatomic pathology diagnostic services for cancer in sub-Saharan Africa: a scoping review protocol by Katherine Van Loon, Elia John Mmbaga, Marcia Edelweiss, Dianna L. Ng, Asteria Herman Kimambo, Edda Vuhahula, Beatrice Paul Mushi, Omolade Adegoke, Johanna Goldberg, Pendo M. Ibrahim, Zainab Illonga, Julia Jackman, Luisa Jamisse

“…Introduction Sub-Saharan Africa bears a disproportionate burden of cancer-related morbidity and mortality compared with high-resource settings. …”
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On the fence: Factors associated with COVID-19 vaccine hesitancy among sexually Minoritized men who use substances in the United States by Renessa S. Williams, Acklynn M. Byamugisha, Leah Davis-Ewart, Omar R. Valentin, Samantha E. Dilworth, Christian Grov, Adam W. Carrico

“…Objective: Substance use during the COVID-19 (SARS-CoV-2) pandemic has exponentially increased among sexually minoritized men (SMM), who are more vulnerable to COVID-19 transmission, morbidity, and mortality than their heterosexual counterparts. …”
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Increased dicentric chromosome in peripheral lymphocytes is related to acute skin toxicity induced by radiotherapy in cancer patients by Minjie Li, Yu Gao, Lin Han, Ping Wang, Jie Li, Junhua Song, Shasha Du, Yunfei Zhang, Yumin Lyu

“…These patients were grouped according to the grade of acute skin and marrow toxicities determined based on the scoring criteria for acute morbidity developed by the Radiation Therapy Oncology Group (RTOG). …”
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Short-term Outcomes of Pancreatoduodenectomy in Patients with Liver Cirrhosis: A Systematic Review and Meta-analysis by Shahab Hajibandeh, MRCS, Shahin Hajibandeh, FRCS, Alwin Puthiyakunnel Saji, Ayman Ashabi, MRCS, Christopher Brown, FRCS, Nicholas G Mowbray, FRCS, Matthew Mortimer, FRCS, Guy Shingler, FRCS, Amir Kambal, FRCS, Bilal Al-Sarireh, FRCS, PhD

“…Robust evidence with high certainty suggests LC of any severity with or without portal hypertension results in at least a fourfold increase in mortality and a twofold increase in morbidity after pancreatoduodenectomy. Whether such risks increase with the severity of the liver disease or decrease with optimization of underlying liver disease should be the focus of future research.…”
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Improving health outcomes and quality at the subdistrict level: Evaluation of the ‘3 feet model’ in Waterberg District, Limpopo Province, South Africa by H Schneider, F Mukinda, J Cupido, J Wessels, P Kupa, P Leboho, N Nkoana, N Bosch, Y Pillay

“…The model is centred on systems of real-time morbidity/mortality surveillance and co-ordinated responses. …”
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Association between physical multimorbidity in middle adulthood and mortality: findings from two large cohort studies in Japan by Yosuke Inoue, Seitaro Suzuki, Norie Sawada, Naho Morisaki, Zui Narita, Taiki Yamaji, Yoshihiro Kokubo, Takehiko Doi, Yukiko Nishita, Motoki Iwasaki, Manami Inoue, Tetsuya Mizoue

“…Multimorbidity was defined as the presence of ≥ 2 of 10 morbidities or conditions based on self-reported information. …”
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Universal conditional networks (UniCoN) for multi-age embryonic cartilage segmentation with Sparsely annotated data by Nishchal Sapkota, Yejia Zhang, Zihao Zhao, Maria Jose Gomez, Yuhan Hsi, Jordan A. Wilson, Kazuhiko Kawasaki, Greg Holmes, Meng Wu, Ethylin Wang Jabs, Joan T. Richtsmeier, Susan M. Motch Perrine, Danny Z. Chen

“…Abstract Osteochondrodysplasia, affecting 2–3% of newborns globally, is a group of bone and cartilage disorders that often result in head malformations, contributing to childhood morbidity and reduced quality of life. Current research on this disease using mouse models faces challenges since it involves accurately segmenting (precisely delineating) the developing cartilage in 3D micro-CT images of embryonic mice. …”
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Prevalence and risk factors of postpartum depression, general depressive symptoms, anxiety and stress (PODSAS) among mothers during their 4-week postnatal follow-up in five public... by Boon How Chew, Subashini Ambigapathy, Saidatul Akmar Mohammad Redzuan, Priyasini Suntharalingam, Thenmoli Palaniyappan, Venotha Ganasan, Puteri Normalina Megat Abu Bakar, Paream Kaur, Lili Zuryani Marmuji, V Paranthaman

“…Introduction Postpartum depression, general depressive symptoms, anxiety and stress (PODSAS) are often overlooked, and may cause morbidity to new mothers, their babies and families. …”
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Early Pregnancy Serum Metabolite Profiles Associated with Hypertensive Disorders of Pregnancy in African American Women: A Pilot Study by Erin P. Ferranti, Jennifer K. Frediani, Rebecca Mitchell, Jolyn Fernandes, Shuzhao Li, Dean P. Jones, Elizabeth Corwin, Anne L. Dunlop

“…Hypertensive disorders of pregnancy (HDP) are the most common cardiometabolic complications of pregnancy, affecting nearly 10% of US pregnancies and contributing substantially to maternal and infant morbidity and mortality. In the US, women of African American race are at increased risk for HDP. …”
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Estimating the global health impact of gender-based violence and violence against children: a systematic review and meta-analysis protocol by Joht Singh Chandan, Emmanuela Gakidou, Jaidev Kaur Chandan, Nicholas Metheny, Mariam Khalil, Cory N Spencer, María Jose Baeza, Alexandra Debure, Molly Herbert, Teresa Jewell, Rachel Qian Hui Lim, Sonica Minhas

“…Introduction Exposure to gender-based violence (GBV) and violence against children (VAC) can result in substantial morbidity and mortality. Previous reviews of health outcomes associated with GBV and VAC have focused on limited definitions of exposure to violence (ie, intimate partner violence) and often investigate associations only with predefined health outcomes. …”
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Focus on Depression in Parkinson’s Disease: A Delphi Consensus of Experts in Psychiatry, Neurology, and Geriatrics by Luis Agüera-Ortiz, Rocío García-Ramos, Francisco J. Grandas Pérez, Jorge López-Álvarez, José Manuel Montes Rodríguez, F. Javier Olazarán Rodríguez, Javier Olivera Pueyo, Carmelo Pelegrín Valero, Jesús Porta-Etessam

“…Major and minor forms of depression are significant contributors to Parkinson’s disease morbidity and caregiver burden, affecting up to 50% of these patients. …”
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Intraperitoneal paclitaxel for patients with primary malignant peritoneal mesothelioma: a phase I/II dose escalation and safety study—INTERACT MESO by Job P van Kooten, Jacobus W A Burger, Cornelis Verhoef, Joachim G J V Aerts, Eva V E Madsen, Alexandra R M Brandt-Kerkhof, Stijn L W Koolen, Ron H J Mathijssen, Michelle V Dietz, Niels A D Guchelaar

“…The benefit of systemic treatment for these patients is limited at the cost of considerable morbidity. Hence, there is a need for appropriate palliative treatment options for patients with MPM. …”
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Effect of smoking cessation on the likelihood of pancreatitis and pancreatic cancer by Xiao Han, Zouhua Xu, Dongmei Ma, Zhi Ling, Xiaowu Dong, Xuebing Yan, Yong Chen, Guotao Lu, Xudong Yin, Hongwei Xu

“…This study sought to determine whether smoking cessation would reduce pancreatitis and PC morbidity. Methods This cohort study used data from the UK Biobank (UKB) to examine the association between smoking status and the likelihood of pancreatitis and PC among 492855 participants. …”
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