The Impact of COVID-19 on Clinical Outcomes in Patients With Traumatic Brain Injury by Farnaz Mahdavi, Sima Fallah-Arzpeima, Zoheir Reihanian, Khatereh Asadi, Nooshin Zaresharifi, Roghaye Zare, Mohammad Ali Yazdanipour, Masoud Shabani Chobe

“…Background: Traumatic brain injury (TBI) is a leading cause of mortality and morbidity worldwide. COVID-19 can impact the central nervous system (CNS) and hematologic system and appears to affect clinical outcomes and the average cerebral hemorrhage volume (ACHV) in patients with TBI. …”
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Identification of Potential Biomarkers and Immune Features of Sepsis Using Bioinformatics Analysis by Fang-Chen Gong, Ran Ji, Yu-Ming Wang, Zhi-Tao Yang, Ying Chen, En-Qiang Mao, Er-Zhen Chen

“…Sepsis remains a major global concern and is associated with high mortality and morbidity despite improvements in its management. Markers currently in use have shortcomings such as a lack of specificity and failures in the early detection of sepsis. …”
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Longitudinal maternal glycemia during pregnancy and placental epigenetic age acceleration by Tesfa Dejenie Habtewold, Prabhavi Wijesiriwardhana, Richard J. Biedrzycki, Cuilin Zhang, Katherine L. Grantz, Jagteshwar Grewal, Fasil Tekola-Ayele

“…Abstract Background Dysregulation of maternal glucose homeostasis has been related to an increased risk of morbidity and mortality in mothers and fetuses, yet the mechanism remains unclear. …”
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Radiomics analysis of thoracic vertebral bone marrow microenvironment changes before bone metastasis of breast cancer based on chest CT by Hao-Nan Zhu, Yi-Fan Guo, YingMin Lin, Zhi-Chao Sun, Xi Zhu, YuanZhe Li

“…Background: Bone metastasis from breast cancer significantly elevates patient morbidity and mortality, making early detection crucial for improving outcomes. …”
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Beyond the fever: shotgun metagenomic sequencing of stool unveils pathogenic players in HIV-infected children with non-malarial febrile illness by Patricia Nabisubi, Stephen Kanyerezi, Grace Kebirungi, Ivan Sserwadda, Mike Nsubuga, Grace Kisitu, Patricia Ntege Nahirya, Bonny Mulindwa, George P. Akabwai, Sylvia Nantongo, Adeodata Kekitiinwa, Edgar Kigozi, Nsubuga Moses Luutu, Fred Ashaba Katabazi, Leymon Kalema, Andrew Katabalwa, Daudi Jjingo, Gerald Mboowa

“…Abstract Background Non-malarial febrile illnesses (NMFI) pose significant challenges in HIV-infected children, often leading to severe complications and increased morbidity. While traditional diagnostic approaches focus on specific pathogens, shotgun metagenomic sequencing offers a comprehensive tool to explore the microbial landscape underlying NMFI in this vulnerable population ensuring effective management. …”
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The Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Patterns: A Nine-Year Retrospective Study at St. Dominic Hospital, Akwatia, Ghana by John Gameli Deku, Mavis Puopelle Dakorah, Sylvester Yao Lokpo, Verner N. Orish, Francis Abeku Ussher, Godsway Edem Kpene, Vida Angmorkie Eshun, Eunice Agyei, Waldermer Attivor, James Osei-Yeboah

“…Bloodstream infections are among the top causes of morbidity and mortality in people of all ages, especially in immunocompromised patients in sub-Saharan Africa. …”
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Identifying malignant pleural effusion from tubercular pleural effusion by study of cancer ratio and cancer ratio plus by Subhankar Saren, Animesh Mandal, Amit Kumar Das, Ranjit Kumar Haldar, Sudipta Pandit

“…Background: Early detection of malignant pleural effusions (MPE) through routine biochemical tests will go a long way in improving morbidity and mortality of these patients. Aims and Objectives: The current study was aimed to observe the usefulness of cancer ratio (CR) and CR plus to diagnose malignant effusions early in disease evolution. …”
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Treatment of Spontaneous Subarachnoid Hemorrhage: A 20‐Year National Inpatient Sample Review by Joshua Feler, Dylan Wolman, Radmehr Torabi, Jia‐Shu Chen, Abigail Teshome, Rahul Sastry, Curtis Doberstein, Mahesh Jayaraman, Krisztina Moldovan, Ali Mahta

“…Background Aneurysmal subarachnoid hemorrhage (aSAH) is a major source of morbidity and mortality, and its management has undergone foundational changes over thepast 2 decades. …”
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Impact of empiric antibiotics on risk of Clostridioides difficile—a causal inference observational analysis by Matthew A. Pappas, Shoshana J. Herzig, Andrew D. Auerbach, Abhishek Deshpande, Eunice Blanchard, Michael B. Rothberg

“… Abstract Background: Clostridioides difficile infection (CDI) is a common and often nosocomial infection associated with increased mortality and morbidity. Antibiotic use is the most important modifiable risk factor, but many patients require empiric antibiotics. …”
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Peripheral neuropathy in the phase 3 ASPEN study of Bruton tyrosine kinase inhibitors for Waldenström macroglobulinemia by Benjamin M. Heyman, Stephen S. Opat, Björn E. Wahlin, Meletios-Athanasios C. Dimopoulos, Jorge J. Castillo, Alessandra Tedeschi, Constantine S. Tam, Christian Buske, Roger G. Owen, Véronique Leblond, Judith Trotman, Gisoo Barnes, Wai Y. Chan, Jingjing Schneider, Heather Allewelt, Aileen Cohen, Jeffrey V. Matous

“…Abstract: Peripheral neuropathy (PN) is a significant cause of morbidity associated with Waldenström macroglobulinemia (WM). …”
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Trends and Clinical Implications of Pediatric Pulmonary Function After Hematopoietic Stem Cell Transplantation: A Systematic Review by Xiaowei Zhao, Yuqi Zhao, Guoyu Ding, Xue Li, Xiaoyue Zhang, Yanli Leng, Hongmei Wang

“…However, post‐transplant pulmonary complications remain a significant cause of morbidity and mortality. Pulmonary Function Tests (PFTs) are essential for the early detection of pulmonary dysfunction, yet their application in pediatric HSCT recipients has yielded inconsistent results. …”
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The hypotension prediction index in major abdominal surgery – A prospective randomised clinical trial protocol by Jakub Szrama, Agata Gradys, Zuzanna Nowak, Ashish Lohani, Krzysztof Zwoliński, Tomasz Bartkowiak, Amadeusz Woźniak, Tomasz Koszel, Krzysztof Kusza

“…Background: Patients undergoing major abdominal surgery are at increased risk of developing perioperative hypotension, which is associated with increased mortality and morbidity. Despite using advanced technologies such as evaluating arterial pressure derived cardiac output, anaesthetic management to maintain hemodynamic stability is still reactive when the clinical decision is made after hypotension has developed. …”
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Long-Term Outcomes Following Inguinal Hernia Repair With Mesh Performed by Medical Doctors and Surgeons in Ghana by Jessica H. Beard, MD, Michael Ohene-Yeboah, MBChB, Emmanuel S. Kasu, MBChB, Nelson Affram, MBChB, Stephen Tabiri, MD, Joachim K. A. Amoako, MBChB, Francis A. Abantanga, MD, Jenny Löfgren, MD

“…Task sharing is a critical tool to address the substantial morbidity of unmet hernia surgery needs in Ghana.…”
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Analysis of clinical characteristics and risk factors for patients with heat stroke in western China in 2022: a multicenter retrospective study by Xin Zheng, Yuchun Gao, Qinli Xie, Qiulan Chen, Chuan Guo, Qionglan Dong, Jin Tang, Jun Luo, Ying Ge, Jian He, Xiaolin Hou, Guanghong Zhou, Yuan Chen, Haiquan Cao, Jiujia Xiao, An Lan, Qiu Chen, Yonghong Zeng, Jing Huang, Huaicong Long

“…The AUC values for the combined diagnostic model were 0.848 (95% CI: 0.781–0.914). Male morbidity, the number of patients with combined hypertension, the prognosis, and the APACHE II score and ALT level were all greater (p < 0.05) in the CHS group. …”
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Clustering of non-communicable disease risk factors among school teachers: A cross-sectional study in Kerala, India by Mini GK, Sangeeth KS, Anand Marthanda Pillai, Sarma PS, Thankappan KR

“…In hypertensives, the most common co-morbidity was being overweight, followed by physical inactivity. …”
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Acute Stroke in northern Portugal: outcomes and characteristics of patients in a Medical-Surgical Emergency Department by Sandra Domingues, Tiago Barros, João Correia, Arlindo Cruz, Nuno Araújo, Liliana Silva

“… Introduction: Stroke is a leading cause of morbidity and long-term disability worldwide, significantly impacting health systems and personal lives. …”
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Management of acute bacterial meningitis in a limited resource setting: an Egyptian consensus model by Samy Zaky, Mohamed Elbadry, Maysaa A. Saeed, Hanaa Fathelbab, Fatma Abdelsalam, Mohammed Gamal Abdel-Hamid, Alshaimaa Eid, Asmaa Bakr, Amira Maher, Mona Mohammed Abdelrahman, Mohamed A. Metwally, Mahmoud Saad Berengy, Enaam Ali AlMowafy, Hassan Goabar, Amin Abdel Baki, Ahmed Corie, Osama Hammad, Entesar Elsharkawy, Ahmed Saad, Fatma Ali-Eldin, Ahmed Mahdy, Ramadan Zaky, Reham Hammad, Gamal Essmat

“…Abstract Acute bacterial meningitis (ABM) is an emerging disease with high morbidity and mortality. It is a globally serious disease and is considered endemic in Egypt, affecting all age groups and being common in low-standard and overcrowded areas. …”
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Mitral Valve Repair in Pediatric Patients with Dilated Cardiomyopathy and Mitral Insufficiency: Single-Center Experience and Results by Mustafa Yılmaz, Başak Soran Türkcan, Ata Niyazi Ecevit, İbrahim Ece, Hazım Alper Gürsu, Atakan Atalay

“…The patients did not develop additional morbidities, and no mortality was observed during hospitalization. …”
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Large-scale prospective serum metabolomic profiling reveals candidate predictive biomarkers for suspected preeclampsia patients by Yan Cao, Lanlan Meng, Yifei Wang, Shenglong Zhao, Yuanyuan Zheng, Rui Ran, Jie Du, Hongqiang Wu, Jiaqi Han, Zhengwen Xu, Yifan Lu, Lin Liu, Lu Chen, Jing Wang, Youran Li, Yanhong Zhai, Zhi Sun, Zheng Cao

“…Abstract Preeclampsia (PE) is a serious pregnancy complication that contributes to maternal and perinatal morbidity and mortality. Understanding its pathogenesis and revealing predictive biomarkers are essential for guiding treatment decisions. …”
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Global, regional, and national incidence and mortality for enteric infections from 1990 to 2019 by Bo Wang, Dongwei Chen, Hua Chen, Wei Wu, Kaiyi Cheng, Yixiu Tao, Ling Zhang, Ce Liu, Ding Ou, Mingxiu Zhang, Xianmei Tang, Shouli Wang, Guangzhu Wang, Bin Luo

“…The aim of this article was to track the global trends in morbidity and mortality from enteric infections in 204 countries or territories from 1990 to 2019. …”
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