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  1. 4501

    Dietary Beliefs and Their Association with Overweight and Obesity in the Spanish Child Population by María Teresa Murillo-Llorente, Alma María Palau-Ferrè, María Ester Legidos-García, Javier Pérez-Murillo, Francisco Tomás-Aguirre, Blanca Lafuente-Sarabia, Adalberto Asins-Cubells, Miriam Martínez-Peris, Ignacio Ventura, Jorge Casaña-Mohedo, Marcelino Pérez-Bermejo

    Published 2025-01-01
    “…Background/Objectives: Childhood obesity is a multifactorial chronic disease that represents one of the main preventable causes of morbidity and mortality. This study analyzes how nutritional beliefs influence eating habits and the prevalence of overweight and obesity in Spanish children and adolescents. …”
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  2. 4502

    The Impact of Amniotic Fluid Interleukin-6, Interleukin-8, and Metalloproteinase-9 on Preterm Labor: A Narrative Review by Theodoros Karampitsakos, Despoina Mavrogianni, Nikolaos Machairiotis, Anastasios Potiris, Periklis Panagopoulos, Sofoklis Stavros, Panos Antsaklis, Peter Drakakis

    Published 2025-01-01
    “…Background/objectives: Preterm labor is a leading cause of neonatal morbidity and mortality worldwide. Previous research has indicated that an inflammatory response or microbial invasion of the amniotic cavity is a pathological condition linked to preterm birth; hence, inflammatory markers such as metalloproteinase-9 (MMP-9), interleukin-6 (IL-6), and interleukin-8 (IL-8) have been utilized to predict preterm delivery. …”
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  3. 4503

    Desmoglein-2 was a novel cancer-associated fibroblasts-related biomarker for oral squamous cell carcinoma by Jin Liu, Zhonghao Sun, Shihui Cao, Hao Dai, Ze Zhang, Jingtao Luo, Xudong Wang

    Published 2025-01-01
    “…Abstract Background Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer with alarmingly high morbidity. The cancer-associated fibroblasts (CAFs) play a pivotal role in tumor development, while their specific mechanisms in OSCC remains largely unclear. …”
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  4. 4504

    MUC2 expression modulates immune infiltration in colorectal cancer by Christophe M. Raynaud, Ayesha Jabeen, Eiman I. Ahmed, Eiman I. Ahmed, Satanay Hubrack, Apryl Sanchez, Shimaa Sherif, Ahmad A. Al-Shaibi, Bernice Lo, Bernice Lo, Jessica Roelands, Davide Bedognetti, Davide Bedognetti, Wouter Hendrickx, Wouter Hendrickx

    Published 2025-01-01
    “…IntroductionColorectal cancer (CRC) is a prevalent malignancy with significant morbidity and mortality worldwide. A deeper understanding of the interaction of cancer cells with other cells in the tumor microenvironment is crucial to devise effective therapeutic strategies. …”
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  5. 4505

    Renal transplant recipient and deceased-donor risk profiles at Wits Donald Gordon Medical Centre, Johannesburg, South Africa: A 9-year review by F van der Schyff, M Barnard, B Ströbele, M de Jager, R Britz, P Gaylard, J Loveland

    Published 2024-04-01
    “…Recipients who were allocated these grafts were characterised, and the Hennepin Transplant Risk Score and the Kidney Transplant Morbidity Index (KTMI) were calculated. Results. …”
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  6. 4506

    Opinions on hypertension care and therapy adherence at the healthcare provider and healthcare system level: a qualitative study in the Hague, Netherlands by Mattijs E Numans, Michiel L Bots, Sytske van Bruggen, Hedwig M M Vos, Rimke C Vos, Guy Rutten, Saskia E van Grondelle, Judith Meijer, Erik van Duin

    Published 2022-07-01
    “…Objectives Hypertension is a common cause of cardiovascular morbidity and mortality. Although hypertension can be effectively controlled by blood pressure-lowering drugs, uncontrolled blood pressure is common despite use of these medications. …”
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  7. 4507

    Unveiling the novel role of circadian rhythms in sepsis and septic shock: unexplored implications for chronotherapy by Stewart D. Ramsay, Stewart D. Ramsay, Stewart D. Ramsay, Marni A. Nenke, Marni A. Nenke, Emily J. Meyer, Emily J. Meyer, David J. Torpy, David J. Torpy, Richard L. Young, Richard L. Young, Richard L. Young, Richard L. Young

    Published 2025-02-01
    “…This review details the circadian disruptions associated with sepsis and septic shock, the influence they have on morbidity and mortality, and the potential clinical benefits of circadian-modulating therapies.…”
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  8. 4508

    A pan-immune panorama of bacterial pneumonia revealed by a large-scale single-cell transcriptome atlas by Kun Xiao, Yan Cao, Zhihai Han, Yuxiang Zhang, Laurence Don Wai Luu, Liang Chen, Peng Yan, Wei Chen, Jiaxing Wang, Ying Liang, Xin Shi, Xiuli Wang, Fan Wang, Ye Hu, Zhengjun Wen, Yong Chen, Yuwei Yang, Haotian Yu, Lixin Xie, Yi Wang

    Published 2025-01-01
    “…Abstract Bacterial pneumonia is a significant public health burden, contributing to substantial morbidity, mortality, and healthcare costs. Current therapeutic strategies beyond antibiotics and adjuvant therapies are limited, highlighting the need for a deeper understanding of the disease pathogenesis. …”
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  9. 4509

    Creation of new anastomosis for management of obstructive symptoms related to gastrojejunal anastomosis in patients who undergo gastric bypass: a case series by Rohit Agrawal, MD, Ethan M. Cohen, MD, Ayowumi A. Adekolu, MD, Soban Maan, MD, Mouaz Haffar, MD, Monica Chowdhry, MD, Shyam Thakkar, MD, Shailendra Singh, MD

    Published 2025-01-01
    “…Surgical revision of the GJ anastomosis is technically challenging and carries significant morbidity, making endoscopic therapies such as endoscopic balloon dilation (EBD) and stent placement the preferred approach. …”
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  10. 4510

    Trends in the prevalence of Chronic Kidney Disease in the United States, 1999–2018 by Mansi Zhuang, Mansi Zhuang, Xiaogang Lv, Yanan Zhu, Nan Zheng, Yiqiang Zhan, Yiqiang Zhan

    Published 2025-01-01
    “…BackgroundChronic Kidney Disease (CKD) is an escalating public health concern in the United States, linked with significant morbidity, mortality, and healthcare costs. Despite known risk factors like age, hypertension, and diabetes, comprehensive studies examining temporal trends in CKD prevalence are scarce. …”
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  11. 4511

    The Global Burden of Emerging and Re-Emerging Orbiviruses in Livestock: An Emphasis on Bluetongue Virus and Epizootic Hemorrhagic Disease Virus by Shanta Barua, Eaftekhar Ahmed Rana, M. Asaduzzaman Prodhan, Syeda Hasina Akter, Jully Gogoi-Tiwari, Subir Sarker, Henry Annandale, Debbie Eagles, Sam Abraham, Jasim M. Uddin

    Published 2024-12-01
    “…These diseases cause significant economic impacts including morbidity, mortality, reduced production, high management costs, and the disruption of international trade. …”
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  12. 4512

    Effects of coenzyme Q10 on endothelial and cardiac function in patients undergoing haemodialysis: study protocol for a pilot randomised controlled trial by Yongxing Xu, Enhong Han, Jianjun Gao, Xinlou Li, Xiaowen Zuo, Huaping Jia, Fugui Liang, Lei Xie

    Published 2020-09-01
    “…Introduction Endothelial and cardiac dysfunction are highly prevalent and are associated with cardiovascular morbidity and mortality among patients undergoing dialysis. …”
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  13. 4513
  14. 4514

    The International Vitreoretinal B-Cell Lymphoma Registry: a protocol paper by David J Wilson, Valérie Touitou, Justine R Smith, Manabu Mochizuki, Hiroshi Takase, Steven Yeh, Alexandra L Farrall, H Nida Sen, Daniel V Vasconcelos-Santos, Joke H de Boer, Ninette H ten Dam-van Loon, Janet L Davis, Anthony J Hall, Mark H B Radford

    Published 2022-07-01
    “…Introduction Vitreoretinal lymphoma is a rare ocular cancer with high morbidity and mortality despite treatment. Diagnosis by cytopathology is often delayed, and various molecular and image-based investigations have been developed. …”
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  15. 4515

    Post-craniotomy infections: A point-by-point approach by Giovanni Carone, Marta Bonada, Evelyn Gisell Belotti, Eugenia D'Angeli, Annica Piccardi, Fabio Martino Doniselli, Guido Gubertini, Cecilia Casali, Francesco DiMeco, Massimiliano Del Bene

    Published 2025-01-01
    “…Despite advances in surgical techniques and infection control protocols, PCNIs still contribute to surgical-related morbidity and mortality. Research question: To address these unresolved questions through a comprehensive literature review. …”
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  16. 4516

    Identification and validation of CDK1 as a promising therapeutic target for Eriocitrin in colorectal cancer: a combined bioinformatics and experimental approach by Jiemiao Shen, Xing Gong, Haili Ren, Xia Tang, Hairong Yu, Yilu Tang, Shen Chen, Minghui Ji

    Published 2025-01-01
    “…Abstract Background Colorectal cancer (CRC) is a prevalent malignancy worldwide, associated with significant morbidity and mortality. Cyclin-dependent kinase 1 (CDK1) plays a crucial role in cell cycle regulation and has been implicated in various cancers. …”
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  17. 4517

    Prenatal malaria exposure and risk of adverse birth outcomes: a prospective cohort study of pregnant women in the Northern Region of Ghana by Akbar Fotouhi, Masud Yunesian, Hawawu Hussein, Mansour Shamsipour, Mohammad Sadegh Hassanvand, Percival Delali Agordoh, Mashoud Alabi Seidu

    Published 2022-08-01
    “…Objective Malaria remains endemic in most of sub-Saharan Africa and has a negative impact among pregnant women, resulting in morbidity and poor birth outcomes. The purpose of this study was to assess the relationship between malaria and adverse birth outcomes among prenatal women in the Northern Region of Ghana.Design This is a prospective cohort study of singleton pregnancies at 28 weeks of gestational age and above recruited between July 2018 and May 2019 from four public hospitals in the Northern Region of Ghana.Outcome measures Low birth weight (LBW), preterm birth and perinatal death.Results A total of 1323 pregnant women completed the study out of the 1626 recruited, with an average age of 27.3±5.2 years. …”
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  18. 4518

    Head-to-head comparison of pre-hospital qSOFA and lactate-qSOFA for predicting sepsis in patients with and without suspected infection. A multicenter prospective cohort study by Francisco Martín-Rodríguez, Raúl López-Izquierdo, Miguel A. Castro Villamor, Carlos delPozo-Vegas, Irene Sánchez-Soberón, Juan F. Delgado-Benito, Virginia Carbajosa Rodíguez, Rodrigues Leonardo, José Luis Martín-Conty

    Published 2020-02-01
    “…Conclusions An appropriate strategy for reducing the morbidity and mortality from sepsis must necessarily include the prompt identification of this time-dependent pathology by using all the tools at our disposal. …”
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  19. 4519

    Gut mycobiome alterations and network interactions with the bacteriome in patients with atherosclerotic cardiovascular disease by Guangming Su, Ping Huang, Dan Liu, Guorui Xing, Ruochun Guo, Shenghui Li, Shao Fan, Lin Cheng, Qiulong Yan, Wei Yang

    Published 2025-01-01
    “…Our findings offer a thorough understanding of the link between the gut mycobiome and ACVD progression, which is vital for directing future therapeutic research.IMPORTANCEACVD is a leading cause of death and morbidity worldwide. While the role of the gut microbiome in ACVD development is recognized, the contribution of the gut mycobiome remains largely unexplored. …”
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  20. 4520

    Energy and Macronutrients Intakes among Childbearing Age Women Living in the Urban Area of Morocco: A Cross-Sectional Study by Fatima Barich, Fatima Zahra Laamiri, Slimane Mehdad, Souad Benaich, Anass Rami, Mohamed Idrissi, Chaimae Serbouti, Houria Lahmame, Hasnae Benkirane, Manelle Rjimati, Amina Barkat, El Arbi Rjimati, Hassan Aguenaou

    Published 2020-01-01
    “…In Morocco, these changes have led to serious nutritional disorders and increased risk of morbidity and mortality particularly among vulnerable groups such as women of childbearing age. …”
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