A current review on animal models of anti-asthmatic drugs screening by Shivam Singh, Sunita Kularia, Shivakshi Shukla, Mithilesh Singh, Manish Kumar, Ashish Kumar Sharma

“…Asthma is a chronic inflammatory respiratory condition characterised by airway constriction, smooth muscle spasm, and severe morbidity. It affects around 300 million people globally, with children being especially vulnerable. …”
Get full text

KLEBSIELLA PNEUMONIAE NECROTIZING FASCIITIS OF THE LOWER EXTREMITY IN A 7-MONTH-OLD MALE: A CASE REPORT by Marelno Zakanito, Iswinarno Doso Saputro

“…This condition may result in gross morbidity and mortality if not treated in its early stages. …”
Get full text

Fetal Tetra-Amelia Birth: A Case Report by Eyob Asefa Belay, Anberbir Girma Asebot, Bezza Kedida Dabi

“…Tetra-amelia syndrome is associated with high mortality and morbidity than isolated tetra-amelia. In this case report, we present an extremely rare case, isolated tetra-amelia, born to G3P2 (Gravida 3, Para 2) mother at 36 weeks of gestation. …”
Get full text

Unveiling the Burden of Pruritus: Its Prevalence and Impact on Sleep Quality in Hemodialysis Patients in Somalia by Jeele MOO, Adam AM, Addow ROB

“…Also, age group, sex, presence of comorbidities, duration of hemodialysis, sessions of hemodialysis per week, and pruritus have shown R2 =  0.34, F (6,292) =  26, p < 0.001.Conclusion: Pruritus is associated with poor sleep and patients who were living with co-morbidities and patients who were going to hemodialysis for a long time tend to develop pruritus. …”
Get full text

Teeth and Covariates: Association with Risk of Falls by Shivani Kohli, Aaron Lam Wui Vun, Christopher Daryl Philip, Cassamally Muhammad Aadil, Mahenthiran Ramalingam

“…Falls occur commonly in geriatric populations and undesirably influence their life, morbidity, and mortality. The aim of this study was to analyze the association between the number of teeth present among the elderly population and covariates in relation to the risk of falls. …”
Get full text

Epigenetic Biomarkers and the Wnt/β-Catenin Pathway in Opisthorchis viverrini-associated Cholangiocarcinoma: A Scoping Review on Therapeutic Opportunities. by Alok Kafle, Sutas Suttiprapa, Mubarak Muhammad, Jan Clyden B Tenorio, Roshan Kumar Mahato, Norhidayu Sahimin, Shih Keng Loong

“…Considering the distinct etiological agent, pathogenic mechanisms, and pathological manifestations, epigenetic research plays a pivotal role in uncovering markers and potential targets related to the cancer-promoting and morbidity-inducing liver fluke parasite prevalent in the Great Mekong Subregion (GMS). …”
Get full text

Development and validation of a high-throughput qPCR platform for the detection of soil-transmitted helminth infections. by Nils Pilotte, Victor Omballa, Monica Voss, Leah Padgett, Malathi Manuel, Jeanne L Goodman, Tim Littlewood, Zayina Zondervenni Manoharan, Lisette van Lieshout, Jaco J Verweij, Manigandan Sekar, Ajith Kumar Muthukumar, Gretchen Walch, Abriana Warren, Mariyam Sheikh, Andrew Gonzalez, Sean R Galagan, Sitara Swarna Rao Ajjampur, Moudachirou Ibikounlé, Steven A Williams, Doug Rains, Ushashi Dadwal, Judd L Walson

“…While these efforts have succeeded in reducing morbidity associated with STH infection, recent modeling efforts have suggested that expanding intervention to treatment of the entire community could achieve transmission interruption in some settings. …”
Get full text

Acute fatty liver of pregnancy: An atypical case report by Riska Subono, Nurul Hikmah

“…Early screening, diagnosis, timely handling delivery, and intensive supportive care are essential to decrease morbidity and mortality for both mother and fetus. …”
Get full text

Clinical, biochemical and molecular characteristics of classic homocystinuria in Saudi Arabia and the impact of newborn screening on prevention of the complications: A tertiary cen... by Ahmed Sarar Mohamed, Talal AlAnzi, Amal Alhashem, Hadeel Alrukban, Fahad Al Harbi, Sarar Mohamed

“…The complication profile was vast, with neuropsychiatric, musculoskeletal, ophthalmic, and thromboembolic morbidities complicating the disease course in 28/33 (85%) of the patients. …”
Get full text

Non-pharmacological Methods Used in the Management of Type 2 Diabetes Mellitus by a Selected Group of People with T2DM in Colombo District, Sri Lanka: A Mixed-Method Study by Lakshani Herath, Manisha Kamalsiri, Perananthan Inthuja, Gayani P Gamage, Dinithi Vidanage

“…Abstract Aims and Objectives: Type 2 diabetes mellitus (T2DM) is one of the most common noncommunicable diseases, which causes high mortality and morbidity among adults. The prevalence of T2DM in Sri Lanka is high due to the unhealthy lifestyles of individuals. …”
Get full text

Prevalence of the polymorphic H-ficolin (FCN3) genes and mannosebinding lectin-associated serine protease-2 (MASP2) in indigenous populations from the Russian Arctic regions by M. V. Smolnikova, S. Yu. Tereshchenko

“…An additional analysis of infectious morbidity in Arctic populations allows one to find phenotypic characteristics related to a high functional activity of the lectin pathway of complement activation as an most important factor for the first-line of anti-infectious defense, including such new viral diseases as COVID-19.…”
Get full text

Prevalence and Associated Factors of Perinatal Asphyxia in Neonates Admitted to Ayder Comprehensive Specialized Hospital, Northern Ethiopia: A Cross-Sectional Study by Gebrehiwot Teklehaimanot Gebregziabher, Fikaden Berhe Hadgu, Haftom Temesgen Abebe

“…It is one of the most common causes of neonatal mortality and morbidity. There are very few studies on perinatal asphyxia in Tigray, and so this study is aimed at assessing the prevalence and associated factors of perinatal asphyxia in Ayder Comprehensive Specialized Hospital NICU, Tigray, Ethiopia. …”
Get full text

Development of risk models for early detection and prediction of chronic kidney disease in clinical settings by Pegah Bahrami, Davoud Tanbakuchi, Monavar Afzalaghaee, Majid Ghayour-Mobarhan, Habibollah Esmaily

“…Abstract Chronic kidney disease (CKD) imposes a high burden with high mortality and morbidity rates. Early detection of CKD is imperative in preventing the adverse outcomes attributed to the later stages. …”
Get full text

Factors Associated with the Utilization of Traditional Health Services among People with Non-Communicable Diseases in Indonesia: Findings from a Nationwide Survey by Iwan Abdi Suandana, Putu Ayu Swandewi Astuti, Pande Putu Januraga

“… Globally, there is an increasing trend of morbidity and mortality from non-communicable diseases (NCDs). …”
Get full text

THE EFFECT OF PROPANOLOL ON C-REACTIVE PROTEIN IN PATIENTS WITH SEVERE BURNS AT DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA by Muhammad Aulia U H, Iswinarno Doso Saputro, Magda Rosalina Hutagalung

“…In severe burns, a hypermetabolic state can occur, which increases cardiac workload and causes muscle atrophy and other morbidities. The purpose of this study is to examine the effect of propranolol on the hypermetabolic state in severely burned patients by measuring various clinical & laboratory parameters. …”
Get full text

Unlocking the Potential of Cecostomies: A Valuable Lifesaving Procedure in Emergency Surgery for Colonic Obstructions by Constantin Popazu, Alexandra Toma, Daniela Mihalache, Oana-Monica Duca, Dorel Firescu, Dragoș F. Voicu

“…In several cases, cecostomies act as a bridge to more definitive surgical treatments, such as resection and anastomosis, and are associated with reduced morbidity and mortality. The selection of cecostomy as a preferred procedure depends on the patient’s condition, location of the obstruction, and surgeon expertise. …”
Get full text

Opioid-related harms and experiences of care among people in justice settings in New South Wales, Australia: evidence from the National Ambulance Surveillance System by Naomi Beard, Michael McGrath, Harry M. X. Lai, James Wilson, Anthony Hew, Amaya Muñoz Labiano, Dan I. Lubman, Rowan P. Ogeil

“…Abstract Background People in justice settings experience higher rates of psychiatric morbidity, including alcohol and drug use disorders, compared with the general population. …”
Get full text

Acute kidney injury, the present on admission (POA) indicator and sex disparities: observational study of inpatient real-world data in a Swiss tertiary healthcare system. Explorati... by Michael Simon, Sarah N Musy, Karen Triep, Olga Endrich

“…As our results show sex differences, that is, a lower morbidity of female patients for each stage, but a higher mortality, a deeper evaluation of the implied sex differences in staging of KD should follow.The general results confirm the necessity of a diagnosis-onset reporting in health statistics.…”
Get full text

Construction and validation of a nomogram predictive model for assessing the risk of surgical site infections following posterior lumbar fusion surgery by Jin-Zhou Luo, Jie-Zhao Lin, Qi-Fan Chen, Chang-Jian Yang, Chu-Song Zhou

“…Abstract Surgical site infections (SSIs) are a significant concern following posterior lumbar fusion surgery, leading to increased morbidity and healthcare costs. Accurate prediction of SSI risk is crucial for implementing preventive measures and improving patient outcomes. …”
Get full text

Harnessing artificial intelligence in sepsis care: advances in early detection, personalized treatment, and real-time monitoring by Fang Li, Shengguo Wang, Zhi Gao, Maofeng Qing, Shan Pan, Yingying Liu, Chengchen Hu

“…Sepsis remains a leading cause of morbidity and mortality worldwide due to its rapid progression and heterogeneous nature. …”
Get full text