Study of Health-Related Quality of Life and Healthcare Utilization among Type 2 Diabetic Population in an Urban Area of Eastern Nepal by Sangita Shah, Nilambar Jha, Deepak Kumar Yadav, Prajjwal Pyakurel, Sanjib Kumar Sharma, Suman Bahadur Singh

“…Diabetes mellitus is a major cause of morbidity and mortality and places huge burden on public health funding. …”
Get full text

Evaluating a multicomponent intervention for managing kidney outcomes among patients with moderate or advanced chronic kidney disease (CKD): protocol for the Strategies for Kidney... by Tazeen Hasan Jafar, Ngiap Chuan Tan, Mihir Gandhi, Sungwon Yoon, Eric Finkelstein, Peter Moey Kirm Seng, Ruiheng Ong, Anandan Gerard Thiagarajah, Bing Long Lee, Ka Chi To, Aminath Shiwaza Moosa

“…Abstract Background Chronic kidney disease (CKD) poses a global health challenge with high morbidity and mortality rates. Early detection and prompt intervention are critical in preventing progression to end-stage kidney disease (ESKD) and cardiovascular complications. …”
Get full text

Mixed vulnerabilities: the biological risk of high parity is aggravated by emergency referral in Benin, Malawi, Tanzania and Uganda by Manuela Straneo, Lenka Beňová, Thomas van den Akker, Muzdalifat S. Abeid, Elizabeth Ayebare, Jean-Paul Dossou, Greta Handing, Bianca Kandeya, Andrea B. Pembe, Claudia Hanson

“…We used e-registry data collected in 16 hospitals included in the Action Leveraging Evidence to Reduce perinatal morbidity and morTality (ALERT) trial. Main outcomes were severe maternal outcomes and in-facility peripartum death (fresh stillbirth or very early neonatal death). …”
Get full text

Effect of Preoperative Nutritional Risk Screening on Postoperative Recovery in Patients with Laparoscopic-Assisted Radical Resection for Colorectal Cancer by Xiaolong Wang, Jianlin Wu, Sen Lei, Feng Tian, Ce Cao, Guangfeng Shi

“…There were no significant differences between the two groups regarding abdominal drainage volume, exhaust (flatus) time, hospitalization cost, morbidity, or 60 d readmission rate (all P>0.05). However, patients with nutritional risk had higher postoperative blood transfusion volumes, albumin infusions, weight difference before and after surgery, and postoperative hospital stays than the nonnutritional risk group (all P<0.05). …”
Get full text

The C825T Polymorphism of the G-Protein β3 Gene as a Risk Factor for Functional Dyspepsia: A Meta-Analysis by Yi-Zuo Song, He-Yi You, Zhe-Hui Zhu, Zheng-De Wen, Hui-Ying Xu, Bi-Cheng Chen, Zong-Jing Chen, Qing-Ke Huang

“…Functional dyspepsia (FD) is a functional upper gastrointestinal disorder with significant morbidity and medical costs. Previous studies investigated the association of G-protein β3 (GNB3) genetic polymorphisms with FD but with inconsistent results. …”
Get full text

Needs and views on eye health and women’s empowerment and theory of change map: implication on the development of a women-targeted eyecare programme for older Zanzibari craftswomen... by Ving Fai Chan, Fatma Omar, Eden Mashayo, Damaris Mulewa, Ai Chee Yong, Christine Graham, Ronnie Graham, Carlos Price-Sanchez, Omar Othman, Kayleigh McCluskey

“…In refining the initial ToC, we used insights from a qualitative study suggesting that improved near vision is perceived by craftswomen as a potential source of empowerment across economic, psychological, social, political and educational dimensions.Results The eye conditions experienced by the craftswomen were eye irritation caused by foreign bodies, the need for near spectacles and other eye morbidities. They were advised by the cooperatives to visit eye health centres for treatment. …”
Get full text

Case report: The Montgomery T tube may be the preferred transition option for achieving a smooth extubation after tracheotomy when complicating airway pathology is present by Jieqiong Wang, Xun Li, Weihua Xu, Nenghui Jiang, Bo Yang, Ming Chen

“…Herein, we present an efficacious strategy addressing these airway morbidities and facilitating rapid tube removal. A 44-year-old male patient, who had undergone tracheostomy due to underlying disease, demonstrated substantial recovery following rehabilitation and was poised for tracheostomy tube extraction. …”
Get full text

Synthesis and evaluation of nitrochromene derivatives as potential antileishmanial therapeutics through biological and computational studies by Niloofar Javid, Ali Asadipour, Ehsan Salarkia, Mohammad Amin Langarizadeh, Fatemeh Sharifi, Mohammad Mahdavi, Bagher Amirheidari, Aida Iraji, Hojjat Rezaiezadeh, Gholamreza Hassanpour, Yaghoub Pourshojaei

“…This disease leads to considerable morbidity and mortality, predominantly within tropical and subtropical regions. …”
Get full text

Mushroom Intoxication in Türkiye: A Nationwide Cohort Study Based on Demographic Trends, Seasonal Variations, and the Impact of Climate Change on Incidence by Dilara Turan Gökçe, Derya Arı, Naim Ata, Hale Gökcan, Ramazan İdilman, Mustafa Mahir Ülgü, Murat Harputluoglu, Mesut Akarsu, Zeki Karasu, Mustafa Okan Ayvalı, Şuayip Birinci, Meral Akdoğan Kayhan

“…Conclusion: Mushroom intoxication is a serious public health issue, with morbidity and mortality influenced by climate factors. …”
Get full text

Fluoroscopic Stenting as a Bridge to Surgery versus Emergency Management for Malignant Obstruction of the Colon by Fan Xue, Feng Lin, Jun Zhou, Ning Feng, You-Gang Cui, Xu Zhang, Yu-Peng Yi, Wen-Zhi Liu

“…Compared to the ES group, the SEMS group has significantly more cases, which featured a laparoscopic approach (72.7% vs. 14.0%, P<0.001), lower overall stoma rate (0% vs. 34.0%, P<0.001), and lower overall postoperative morbidity (27.3% vs. 56.0%, P=0.010). The oncological outcomes did not differ significantly between the two groups in terms of three-year overall survival (P=0.125). …”
Get full text

The multidrug-resistant Candida auris, Candida haemulonii complex and phylogenetic related species: Insights into antifungal resistance mechanisms by Lívia S. Ramos, Pedro F. Barbosa, Carolline M.A. Lorentino, Joice C. Lima, Antonio L. Braga, Raquel V. Lima, Lucas Giovanini, Ana Lúcia Casemiro, Nahyara L.M. Siqueira, Stefanie C. Costa, Célia F. Rodrigues, Maryam Roudbary, Marta H. Branquinha, André L.S. Santos

“…Notably, C. auris is classified in the critical priority group on the World Health Organization's fungal priority pathogens list, which highlights fungal species capable of causing systemic infections with significant mortality and morbidity risks as well as the challenges posed by their MDR profiles, limited treatment and management options. …”
Get full text

Correlation between malondialdehyde level and FOXO3 and CASP3 mRNA expression changed in early-onset preeclampsia placenta by Ni Made Wiasty Sukanty, Febriana Catur Iswanti, Syarifah Dewi, Muhammad Faruqi, Alyssa Shafa Andiana, Ani Retno Prijanti

“… Background: Preeclampsia is one of the factors causing the high maternal mortality rate. The risk of morbidity and mortality is higher in Early Onset Preeclampsia (EOPE). …”
Get full text

UPLC-DAD-QTOF/MS Analysis of Flavonoids from 12 Varieties of Korean Mulberry Fruit by O-Chul Kwon, Wan-Taek Ju, Hyun-Bok Kim, Gyoo-Byung Sung, Yong-Soon Kim

“…Mulberry (Morus alba L.) has been used in East Asia (Korea, China, and Japan) as a medicine because of its various pharmacological effects including the excellent antioxidant properties of its fruit. …”
Get full text

Clinico-pathological profile of patients with HIV and tuberculosis co-infection by Cheryl Sarah Philipose, Sinchana KM, Haritha Haridas, John Ramapuram, Sharada Rai

“…Introduction Human immunodeficiency virus (HIV) and tuberculosis (TB) are two main leading global causes of mortality and morbidity. TB and HIV increase progressive deterioration of immunological functions by speeding progression of one another. …”
Get full text

Elevated Liver Function Tests as Predictors of Severe Maternal Outcomes in Women with Preeclampsia by Sadia Chaudhary, Hafiza Ateeqa Mubarak, Anila Sabir, Hina Sadaf, Anas Khalil, Zahid Mahmood, Marium Shoukat, Farah Naz Tahir

“… Background: Preeclampsia is a hypertensive disorder of pregnancy that ultimately led to high mortality and morbidity due to its complication HELP (Hemolysis, Elevated Liver Enzymes, and Low Platelet count), syndrome, and its association with elevated liver function tests. …”
Get full text

Sickle Cell Nephropathy and Associated Factors among Asymptomatic Children with Sickle Cell Anaemia by Uchenna Modestus Nnaji, Christian Chukwukere Ogoke, Henrietta Uche Okafor, Kingsley I. Achigbu

“…In Southeast Nigeria, few studies have evaluated renal function in paediatric SCA patients for early detection of renal impairment and early intervention to reduce morbidity and mortality. Therefore, this study evaluated the renal function of paediatric SCA patients in a steady state based on glomerular filtration rate and urinalysis findings (proteinuria and haematuria). …”
Get full text

Laparoendoscopic Rendezvous for Concomitant Cholecystocholedocholithiasis: A Successful Modality Even in the Most Difficult Presentations Including Pregnancy by Bader Hamza Shirah, Zaher Abdulaziz Mikwar, Akram Neyaz Ahmad, Yaser Mohammed Dahlan

“…Residual stone, postoperative complications, postoperative morbidity, and postoperative mortality were 0 (0%). …”
Get full text

Old Plants for New Food Products? The Diachronic Human Ecology of Wild Herbs in the Western Alps by Mousaab Alrhmoun, Aurora Romano, Naji Sulaiman, Andrea Pieroni

“…The study highlights the economic potential of several wild species in these alpine areas, such as <i>Achillea</i>, <i>Artemisia</i>, <i>Verbascum</i>, <i>Veronica</i>, <i>Viola</i>, <i>Polygonum</i>, <i>Bunium</i>, and <i>Sorbus</i> spp., which could be utilized for creating new herbal teas, artisanal beers, liqueurs, ice creams, sweets, and seasoned food products. …”
Get full text

Gambaran Penyakit Malaria di Puskesmas Tarusan dan Puskesmas Balai Selasa Kabupaten Pesisir Selatan periode Januari - Maret 2013 by Tuti Gusra, Nuzulia Irawati, Delmi Sulastri

“…The disease is still being a major health problem in Indonesia because it can cause morbidity and mortality. West Sumatra province is one of the provinces in Indonesia that has high malaria rate. …”
Get full text

miR-181a-5p Inhibits Pyroptosis in Sepsis-Induced Acute Kidney Injury through Downregulation of NEK7 by Meng Zhang, Deyuan Zhi, Jin Lin, Pei Liu, Yajun Wang, Meili Duan

“…Sepsis-induced acute kidney injury (S-AKI) has high morbidity and mortality, of which the pathophysiological mechanisms have not been completely illuminated, leading to nonspecific therapies. …”
Get full text