Evaluation of Risk Factors for Antibiotic Resistance in Patients with Nosocomial Infections Caused by Pseudomonas aeruginosa by Meliha Cagla Sonmezer, Gunay Ertem, Fatma Sebnem Erdinc, Esra Kaya Kilic, Necla Tulek, Ali Adiloglu, Cigdem Hatipoglu

“…Pseudomonas aeruginosa (P. aeruginosa) is resistant to various antibiotics and can cause serious nosocomial infections with high morbidity and mortality. In this clinical study, we investigated the risk factors in patients who were diagnosed with P. aeruginosa-related nosocomial infection. …”
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Association between bacterial presence in urinalysis and hypertension during pregnancy in women at Margono Hospital, Purwokerto: A single-center study in Indonesia by Dina Marlina, Aditya Utomo, Putri Nadhira Adinda Adriansyah, Herman Sumawan, Budi Handono, Muhammad Alamsyah Aziz

“…Hypertensive disorders of pregnancy, a leading cause of maternal morbidity, may be associated with urinary tract infections. …”
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Individualized prediction of stroke-associated pneumonia for patients with acute ischemic stroke by Lulu Zhang, Qi Wang, Qi Wang, Yidan Li, Qi Fang, Xiang Tang

“…BackgroundStroke-associated pneumonia (SAP) remains a neglected area despite its high morbidity and mortality. We aimed to establish an easy-to-use model for predicting SAP.MethodsTwo hundred seventy-five acute ischemic stroke (AIS) patients were enrolled, and 73 (26.55%) patients were diagnosed with SAP. …”
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Medical care in the fight against COVID-19. Cienfuegos Pediatric University Hospital 2021-2022 by Lairí García Ríos, Milenys Acosta Fonseca, Juan Carlos Yanes Macías, Jesús Alberto García Sosa, Aymé Marrero Gil, Diana Rosa Sánchez Cabrera

“…<br /><strong>Objective:</strong> to describe the medical services organization and hospital morbidity during COVID-19, from January 2021 to February 2022, at the Cienfuegos pediatric hospital.…”
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Enhancing glioblastoma therapy: unveiling synergistic anticancer effects of Onalespib - radiotherapy combination therapy by Julia Uffenorde, Mehran Hariri, Eleftherios Papalanis, Annika Staffas, Josefine Berg, Bo Stenerlöw, Hanna Berglund, Christer Malmberg, Diana Spiegelberg, Diana Spiegelberg

“…BackgroundGlioblastoma (GBM) is the deadliest form of brain cancer, impacting both adults and children, marked by exceptionally high morbidity and mortality rates, even with current standard treatments such as surgery, radiation therapy, and chemotherapy. …”
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Lack of reactivation of tuberculosis in patients with psoriasis treated with secukinumab in a real-world setting of latent tuberculosis infection by Matteo Megna, Cataldo Patruno, Maria Rita Bongiorno, Alessio Gambardella, Claudio Guarneri, Caterina Foti, Serena Lembo, Francesco Loconsole, Gabriella Fabbrocini

“…Background Some biologics for psoriasis, especially anti-tumor necrosis factor (TNF)-α therapies, may re-activate latent tuberculosis (TBC) infection with consequent morbidity and mortality. However, there is a low reported incidence of conversion to positive TBC status among patients with psoriasis treated with second-generation biologic therapies, particularly anti-interleukin (IL)-17 therapies such as secukinumab.Objectives To evaluate the safety profile of secukinumab in psoriasis patients with latent TBC infection.Methods Real-life data were collected by retrospective chart review on patients with moderate-to-severe psoriasis who showed positivity for TBC screening at baseline and underwent secukinumab treatment for psoriasis at six Italian centers. …”
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Extreme Environment Streptomyces: Potential Sources for New Antibacterial and Anticancer Drug Leads? by Periyasamy Sivalingam, Kui Hong, John Pote, Kandasamy Prabakar

“…Consequently, the increased morbidity and mortality, which are associated with multidrug resistance bacteria, urgently require the discovery of novel and more efficient drugs. …”
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Evaluation of Mannheim Peritonitis Index Score for predicting the outcomes in patients with peritonitis by Raiba Deshmukh, Avishkar K Barase, Rutik P Gandhi, Aniket Chaware, Avinash Dhumal

“…Conclusion: MPI score is a simple, effective, and useful system for predicting post-operative mortality and morbidity in cases of peritonitis. Patients with high MPI scores were found to be having higher mortality. …”
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Clonality and the Phenotype–Genotype Correlation of Antimicrobial Resistance in <i>Acinetobacter baumannii</i> Isolates: A Multicenter Study of Clinical Isolates from Romania by Adrian-Gabriel Pană, Pavel Șchiopu, Dan Alexandru Țoc, Vlad Sever Neculicioiu, Anca Butiuc-Keul, Anca Farkas, Matei-Ștefan Dobrescu, Mirela Flonta, Carmen Costache, Izabella Éva Szász, Lia-Monica Junie

“…Antibiotic resistance is on the WHO’s top 10 list of global public health threats due to its rapid emergence and spread but also because of the high morbidity and mortality associated with it. Amongst the main species driving this phenomenon is <i>A. baumannii</i>, a member of the ESKAPE group of medical assistance-associated infections causing species famous for its extensively drug-resistant phenotypes. …”
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Foodborne Event Detection Based on Social Media Mining: A Systematic Review by Silvano Salaris, Honoria Ocagli, Alessandra Casamento, Corrado Lanera, Dario Gregori

“…Foodborne illnesses represent a significant global health challenge, causing substantial morbidity and mortality. Conventional surveillance methods, such as laboratory-based reporting and physician notifications, often fail to enable early detection, prompting the exploration of innovative solutions. …”
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Epidemiologic characteristics, the length of hospital stay, and mortality of patients with organophosphate poisoning: A systematic review by Janet Alva, Elsa Sanatombi Devi, Ramesh Chandrababu, Julliet Abraham, Jayraj Mymbilly Balakrishnan

“…The mass awareness to be created for the public to ensure the victim reaches the hospital for immediate medical care to prevent mortality and minimize morbidity.…”
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Changes in Glucose Metabolism and Atherogenic Risk Factors in Diabetic Patients’ First-degree Relatives by María Teresa González Pedroso, Elizabeth Remis Rodríguez, Marlene Ferrer Arrocha, Marisela Nuez Villar, Ingrid Rodríguez Crespo, Héctor Pérez Assef

“…<strong>Foundation:</strong> diabetes mellitus is one of the diseases with the highest morbidity and mortality among non-communicable chronic conditions and its prevalence in individuals with a first-degree family history is high. …”
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Fungal Infections in Kidney Transplant Recipients: A Comprehensive Narrative Review by Maria Mazzitelli, Federico Nalesso, Alberto Enrico Maraolo, Vincenzo Scaglione, Lucrezia Furian, Annamaria Cattelan

“…Background: Despite kidney transplantation being a life-saving procedure, patients experience a high risk of developing fungal infections (FIs), with an increased risk of both morbidity and mortality, especially during the first year after transplant. …”
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Using maternal sepsis patient journeys to map and prioritise barriers to quality maternal healthcare in Malawi: a multidisciplinary stakeholder consultation workshop by Yamikani Chimwaza, Dalisto Ndaferankhande, Leonard Mndala, Chifundo Ndamala, Emily Lifa, Mercy Machilika, Esther Mwagomba, Bernard Dossie, Meliya Kwelepeta, Bertha Maseko, David Lissauer, Maria Lisa Odland

“…They have the potential to guide strategic improvements in maternal healthcare quality and ultimately reduce maternal morbidity and mortality.…”
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KLF12 Aggravates Angiotensin II‐Induced Cardiac Remodeling in Male Mice by Transcriptionally Inhibiting SMAD7 by Min Hu, Shi‐Yu Huang, Yi‐Peng Gao, Yu‐Xin Hu, Sha‐Sha Wang, Teng Teng, Xiao‐Feng Zeng, Qi‐Zhu Tang

“…Background Adverse left ventricular remodeling and subsequent heart failure remain a major cause of patient morbidity and mortality worldwide. The KLF family of transcription factors plays crucial roles in heart injury. …”
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Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association by Albin Abraham, Seth Lipka, Rabab Hajar, Bhuma Krishnamachari, Ravi Virdi, Bobby Jacob, Prakash Viswanathan, Paul Mustacchia

“…Overweight and obese subjects were significantly more likely to have ErE than individuals with a normal BMI, with the highest risk seen in the morbidly obese (OR 6.26; 95% CI 3.82–10.28; p<0.0001). …”
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Impact of Benign Prostatic Hyperplasia Pharmacological Treatment on Transrectal Prostate Biopsy Adverse Effects by Marina Zamuner, Ciro Eduardo Falcone, Arnaldo Amstalden Neto, Tomás Bernardo Costa Moretti, Luis Alberto Magna, Fernandes Denardi, Leonardo Oliveira Reis

“…Benign prostatic hyperplasia (BPH) pharmacological treatment may promote a decrease in prostate vascularization and bladder neck relaxation with theoretical improvement in prostate biopsy morbidity, though never explored in the literature. …”
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Obesity Status and Colorectal Cancer Screening in the United States by Karima A. Kendall, Euni Lee, Ilene H. Zuckerman, Linda Simoni-Wastila, Marlon Daniel, Pauline M. Green, Beatrice Adderley-Kelly, Anthony K. Wutoh

“…Of a 15,769 Medicare beneficiaries sample aged 50 years and older reflecting 39 million Medicare beneficiaries in the United States, 25% were classified as obese, consisting of 22.4% “obese” (30 ≤ body mass index (BMI) < 35) and 3.1% “morbidly obese” (BMI ≥ 35) beneficiaries. Almost 38% of the beneficiaries had a body mass index level equivalent to overweight (25 ≤ BMI < 30). …”
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Economics of Acute Kidney Injury in the Critical Care Setting: Kidneys Need More Time and Money! by Reema Nair, Somu G, Srinivas Vinayak Shenoy, Laxmitha Shetty, Aparna Satish

“…Background: Acute kidney injury (AKI) is a frequent complication among critically ill patients, contributing significantly to morbidity, mortality, and healthcare costs. Despite its impact, limited studies exist on the economic burden of AKI, particularly in the Indian healthcare context.Methods: From January to April 2021, we conducted a singlecenter, cross-sectional observational study at Kasturba Medical College, Manipal. …”
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A Comparative Study of the Effect of Sutureless Versus Multiple Sutures Technique on Complications following Third Molar Surgery in Nepalese Subpopulation by Arun Kr. Mahat, Ram Yadav, Anjani Kr. Yadav, Pradeep Acharya, Ashok Dongol, Alok Sagtani, Mehul R. Jaisani

“…Our results support the use of sutureless technique after third molar surgery to minimize postoperative morbidity and the overall operative time and reduce the cost within the Nepalese subpopulation.…”
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