Methicillin-Resistant Staphylococcus aureus: Docking-Based Virtual Screening and Molecular Dynamics Simulations to Identify Potential Penicillin-Binding Protein 2a Inhibitors from... by Motahareh Masumi, Fatemeh Noormohammadi, Fatemeh Kianisaba, Fatemeh Nouri, Mohammad Taheri, Amir Taherkhani

“…The binding affinity of SauPBP2a to beta-lactam antibiotics is low, and thus, it is necessary to discover new effective SauPBP2a inhibitors to combat mortality and morbidity in patients affected by MRSA. The binding affinity of 46 natural flavonoids to the SauPBP2a active site was examined via molecular docking analysis. …”
Get full text

Sarcopenia and Frailty in Older Adults in Medellin. SABE Colombia 2015 Survey by Patiño-Villada, Fredy Alonso, Deossa-Restrepo, Gloria Cecilia, Estrada-Restrepo, Alejandro, Benjumea-Rincón, María Victoria

“…Early detection of these syndromes and timely management will help reduce morbidity and mortality, contributing to healthier aging.…”
Get full text

A CASE REPORT: THE STAGED RETRO AURICULAR FLAPS FOR AURICLE RECONSTRUCTION AFTER TRAUMATIC AMPUTATIONS by Alexandria Stephanie Suparman, Doni Setiawan, Yugos Juli Fitra

“…Conclusion: SRF is an efficient ear reconstruction technique that offers relatively little operational morbidity and can restore the ear's size and shape with good to exceptional functional and cosmetic results when used on appropriately chosen helical ear abnormalities.…”
Get full text

Assessment of adherence to dietary recommendations and associated factors among type 2 diabetic patients in selected hospitals in Addis Ababa, Ethiopia by Wabi Temesgen Atinafu, Kefyalew Naniye Tilahun

“…BackgroundIn Ethiopia, diabetes and its complications are significant causes of morbidity and mortality, with huge economic implications. …”
Get full text

Investigating the Effect of Prompt Treatment on Malaria Prevalence in Children Aged below Five Years in Zambia: A Nested Case-Control Study in a Cross-Sectional Survey by Mukumbuta Nawa

“…In a highly malaria endemic country like Zambia, prompt treatment of cases is known to reduce morbidity and mortality; however, it is not known whether it has a role as an effective prevention strategy because of the presence of asymptomatic chronic carriers who do not seek treatment and maintain the reservoirs of infection in the population. …”
Get full text

Prevalence and determinants of restrictive lung disorder among quarry workers at the Umuoghara quarry site, Ebonyi State, Nigeria: a cross-sectional study by Ngozika Substance Ike-Samuel, Osaeloka C. Ekwueme, Susan Chioma Udeh

“…Abstract Introduction Respiratory disorders pose a serious health risk for quarry workers exposed to dust, as they are a leading source of morbidity and mortality globally, often resulting in irreversible lung conditions. …”
Get full text

Endovascular treatments, predictors and outcomes of cerebral aneurysm by Daniel Encarnación Santos, Gennady Chmutin, Ahmad Rami Kassar, Aysi Gordon Gullanyi, Ismail Bozkurt, Jack Wellignton, Bipin Chaurasia

“… Background: Recent studies in surgical techniques have significantly transformed therapeutic approaches, leading to substantial decreases in morbidity and mortality rates. Differential diagnosis plays a pivotal role in determining the most suitable surgical strategies for addressing aneurysms. …”
Get full text

Maternal And Fetal Outcome in Placenta Previa: A Multicenter Prospective Observational Study by Beenish Khan, Syeda Surayya Jabeen, Fatima Sharif Khan, Faria Mumtaz, Reema Gul, Qudsia Nawaz

“…It may lead to increased morbidity and mortality of the mother and the baby if not diagnosed and managed properly. …”
Get full text

Heart and skeletal muscle inflammation – novel dangerous disease of farmed Salmonidae by V. P. Melnikov, V. V. Pronin

“…Total cumulative mortality can reach 30% and morbidity can amount to 100%. Loss of quality of the commercial fish products due to melanised foci in the salmons’ muscles further increases the disease-associated economic losses. …”
Get full text

Effects of Retrofit Strategies on Thermal Comfort and Energy Performance in Social Housing for Current and Future Weather Scenarios by Lucienne G. Basaly, Arman Hashemi, Heba Elsharkawy, Darryl Newport, Nancy Mahmoud Badawy

“…With growing concerns over energy and heat-related mortality/morbidity rates, enhancing building performances is key to improving the health and well-being of building occupants while reducing CO₂ emissions, in line with the UK Government’s Net-Zero targets. …”
Get full text

Perinatal Outcome of Previable Premature Rupture of Membranes Before 24 Weeks of Gestation: A Single-Centered Retrospective Cohort Study by Yasemin Dogan, Ercan Kockaya, Muzeyyen Dilsad Eser, Ayla Gunlemez

“…Of the survivors, twelve babies (66%) were discharged without composite neonatal morbidity. Maternal complications in the expectant management group included clinical chorioamnionitis (n=12, 33%) and placental abruption (n=2, 5%). …”
Get full text

Screening for Atrial Fibrillation by Digital Health Technology in Older People in Homecare Settings: A Feasibility Trial by Edvard Liljedahl Sandberg, Sigrun Halvorsen, Trygve Berge, Jostein Grimsmo, Dan Atar, Bjørnar Leangen Grenne, Jarle Jortveit

“…Atrial fibrillation (AF) is a common and frequently undiagnosed arrhythmia in the elderly and is associated with severe mortality, morbidity, and healthcare costs. Timely identification prevents associated complications through evidence-based treatment. …”
Get full text

Rapid Point-of-Care Influenza Testing for Patients in German Emergency Rooms – A Cost-Benefit Analysis by Roland Diel, Albert Nienhaus

“…**Background:** Each year, influenza causes significant morbidity and death worldwide and produces significant economic losses at the expense of the healthcare system. …”
Get full text

Prevalence of Cardiovascular Risk Factors in the Population of the Area I in the Municipality of Cienfuegos by Hilda María Delgado Acosta, Karelis Lastre Navarro, María Lina Valdés Gómez, Mikhail Benet Rodríguez, Alain Morejón Giraldoni

“…<strong>Background:</strong> since the beginning of the epidemiological transition, there was a prevalence of morbidity and mortality from non communicable diseases, mainly cardiovascular disease. …”
Get full text

Reconstruction by Pancreaticogastrostomy versus Pancreaticojejunostomy following Pancreaticoduodenectomy: A Meta-Analysis of Randomized Controlled Trials by YinFeng Shen, WenYin Jin

“…In the combined results of PG versus PJ, a significant difference in the morbidity of intra-abdominal complications (OR, 0.34; 95% CI, 0.23–0.49; 𝑃<0.00001) was found, but no significant difference could be found for pancreatic fistula (OR, 0.69; 95% CI, 0.42–1.12 , 𝑃=0.13) mortality (OR, 1.09; 95% CI, 0.42–2.83; 𝑃=0.87), recovery with no complications (OR, 1.26; 95% CI, 0.90–1.78; 𝑃=0.18), biliary fistula (OR, 0.55; 95% CI, 0.22–1.35; 𝑃=0.19), or in delayed gastric emptying (OR, 0.55; 95% CI, 0.33–1.01; 𝑃=0.06). …”
Get full text

Prevalence of acute kidney injury in Mexico; a systematic review and meta-analysis of pre-pandemic reports by Jose J. Zaragoza, Jonathan S. Chavez-Iñiguez, Armando Vazquez-Rangel

“…Background Acute Kidney Injury (AKI) is a health problem worldwide, accounting for high hospital morbidity and mortality. There is little available information regarding the characteristics and incidence of AKI in Latin America (LA), especially in Mexico.Objectives Systematically search the literature and perform a meta-analysis of the epidemiology of AKI in Mexico, to provide data on AKI and kidney replacement therapy (KRT) that would contribute to general knowledge in this matter.Methods We performed a systematic search for articles in pediatric and adult patients admitted to the general ward, Emergency Room or Intensive Care Unit published between January 1, 2000, and September 30, 2024. …”
Get full text

Manganese Neurotoxicity as a Complication of Chronic Total Parenteral Nutrition by Alisha Khan, Jonathan Hingre, Amit S. Dhamoon

“…However, when used over a period of several weeks to months, its associated risks and complications carry significant morbidity and mortality. One of the more rare complications of TPN use is manganese toxicity. …”
Get full text

A bird's eye view of the mental health systems in India by Satish Suhas, Banavaram A. Arvind, Gautham M. Sukumar, Pradeep S. Banandur, Lakshmi P. Nirisha, Channaveerachari N. Kumar, Vivek Benegal, Girish N. Rao, Mathew Varghese, Gopalkrishna Gururaj, NMHS National Collaborators Group

“…The methodology involved data collection from various sources and interviews with key stakeholders, yielding a set of 15 quantitative, 5 morbidity, and 10 qualitative indicators, which were employed to encapsulate the functional status of mental health systems within the surveyed states by using a scorecard framework. …”
Get full text

Nasopharyngeal carriage of Streptococcus pneumoniae in Latin America and the Caribbean: A systematic review and meta-analysis. by Martín Brizuela, María Carolina Palermo, Tomás Alconada, María Macarena Sandoval, Eugenia Ramirez Wierzbicki, Joaquín Cantos, Paula Gagetti, Agustín Ciapponi, Ariel Bardach, Silvina Ruvinsky

“…<h4>Background</h4>Streptococcus pneumoniae is a leading cause of morbidity and mortality globally, causing bacteremic pneumonia, meningitis, sepsis, and other invasive pneumococcal diseases. …”
Get full text

Job Description of Community Police Officers of the National Police of Ukraine by V. I. Barko, V. V. Barko

“…It has been emphasized that scientifically substantiated professional research of professional police activity will create favorable conditions for increasing the efficiency of professional selection of personnel and appointment of police officers, will promote more efficient use of personnel potential of police units, enable improvement of training, retraining and professional development of police officers, rationalization of working conditions, reduction of morbidity, etc. Based on a broad pilot study involving police officers from 25 regions of the state, the authors have established a list of the main professional qualities of community police officer, have defined qualitative and quantitative psychological and psycho-physiological indicators recommended for professional activity, the authors have also established psychological and psycho-physiological contraindications to the professional activity of community police officers.…”
Get full text