Hyperuricemia-induced complications: dysfunctional macrophages serve as a potential bridge by Wenyi Gu, Wenyi Gu, Jiajing Zhao, Yu Xu, Yu Xu, Yu Xu

“…With the changes in modern life, hyperuricemia (HUA) has become a serious universal health issue, leading to rising morbidity and mortality. Characterized by elevated levels of UA, HUA has become an independent risk factor for gout, chronic kidney disease, insulin resistance, cardiovascular disease, nonalcoholic fatty liver disease, etc. …”
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Live birth prevalence of major congenital anomalies in the United Arab Emirates by Hiba Adam, Nadirah Ghenimi, Hassib Narchi, Amir Ahmad, Omniyat M. Al Hajeri, Iffat Elbarazi, Rami H. Al-Rifai, Luai A. Ahmed

“…Abstract Major congenital anomalies (MCAs) significantly contribute to perinatal mortality and morbidity. Globally, the United Arab Emirates has the sixth-highest prevalence rate of congenital anomalies. …”
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Canine distemper outbreak and laryngeal paralysis in captive tigers (Panthera tigris) by Sarin Suwanpakdee, Anuwat Wiratsudakul, Nattarun Chaisilp, Luxsana Prasittichai, Anurux Skulpong, Patarapol Maneeorn, Benjaporn Bhusri, Chalisa Mongkolpan, Ruangrat Buddhirongawatr, Jarupa Taowan, Peerawat Wongluechai, Nlin Arya, Parin Suwannaprapha, Natharin Ngamwongsatit, Witthawat Wiriyarat, Nareerat Sangkachai

“…We followed up on their infection from May 2016 to October 2020 with laboratory testing and veterinary medical records. The cumulative morbidity and mortality rates were relatively high. …”
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Effect of intermittent urethral catheter clamping combined with active urination training (ICCAUT) strategy on postoperative urinary dysfunction after radical rectal cancer surgery... by Yuchen Guo, Quan Wang, Tingting He, Sen Liang, Yunan Guan, Jianan Sun, Haiyan Hu

“…Secondary end points include urinary tract infection, time to first urination after catheter removal, catheter-related bladder discomfort syndrome, postoperative morbidity and mortality and urinary function within 30 days.Ethics and dissemination This trial was approved by the Ethics Review Committee of the First Hospital of Jilin University (24K047-001). …”
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The Effects of Thyroid Hormone Levels on Patent Ductus Arteriosus Closure in Newborns by Basak KAYA, Hasan AKDUMAN, Dilek DILLI, Semra CETINKAYA, Ahmet OKTEM, Utku Arman ORUN, Mehmet TASAR, Aysegul ZENCIROGLU

“…Conclusions: Because hs-PDA is associated with increased morbidity and mortality in the neonatal period, especially in premature infants, we hypothesize that thyroid hormone levels may play a role in the closure of hs-PDA.…”
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Risk Factors Associated with Prevalence of Candida albicans, Gardnerella vaginalis, and Trichomonas vaginalis among Women at the District Hospital of Dschang, West Region, Cameroon by Vincent Khan Payne, Tsonang Tassongwa Florence Cécile, Yamssi Cedric, Noumedem Anangmo Christelle Nadia, Ouaba José

“…Vaginal or genitourinary infections are a major cause of morbidity, sterility, and increase in the vulnerability to cancers and HIV/AIDS infection. …”
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Resistant Hypertension and Obstructive Sleep Apnea in the Primary-Care Setting by M. Demede, A. Pandey, F. Zizi, R. Bachmann, M. Donat, S. I. McFarlane, G. Jean-Louis, G. Ogedegbe

“…Logistic regression analysis, adjusting for effects of age, gender, and medical co morbidities, showed that patients with RH were nearly 2.5 times more likely to be at high OSA risk, relative to those with hypertension (OR = 2.46, 95% CI: 1.03–5.88, P<.05). …”
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The Role of PDGFs and PDGFRs in Colorectal Cancer by Roberta M. Manzat Saplacan, Loredana Balacescu, Claudia Gherman, Romeo I. Chira, Anca Craiu, Petru A. Mircea, Cosmin Lisencu, Ovidiu Balacescu

“…Colorectal cancer (CRC) is an important cause of morbidity and mortality worldwide. Angiogenesis was reported as one important mechanism activated in colorectal carcinogenesis. …”
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Feasibility and Safety of Bariatric Surgery in High-Risk Patients: A Single-Center Experience by Yusef Moulla, Orestis Lyros, Matthias Blüher, Philipp Simon, Arne Dietrich

“…Despite the feasibility and safety of bariatric procedures nowadays, high-risk patients with vast obesity and severe comorbidities demonstrate relatively high perioperative morbidity and mortality rates and, therefore, form a distinguished challenge for the bariatric surgeons. …”
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Case Report: Respiratory outcome in a preterm infant following previable rupture of membranes and persistent oligohydramnios by Akila Subramanian, Ong Kai Zhi, Arun Kumar Pugalenthi, Arun Kumar Pugalenthi, Arun Kumar Pugalenthi, Arun Kumar Pugalenthi, Victor Samuel Rajadurai, Victor Samuel Rajadurai, Victor Samuel Rajadurai, Victor Samuel Rajadurai, Lay Kok Tan, Suresh Chandran, Suresh Chandran, Suresh Chandran, Suresh Chandran

“…In addition, there is an increased risk of miscarriage, preterm birth, and chorioamnionitis, contributing to septic morbidity in the mother–baby dyad. This case report describes the management and outcomes of an infant born at 32 weeks following the rupture of membranes at 16 weeks of gestation, resulting in severe oligohydramnios. …”
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Few Associations Found between Mold and Other Allergen Concentrations in the Home versus Skin Sensitivity from Children with Asthma after Hurricane Katrina in the Head-Off Environm... by L. F. Grimsley, J. Wildfire, M. Lichtveld, S. Kennedy, J. M. El-Dahr, P. C. Chulada, R. Cohn, H. Mitchell, E. Thornton, M. Mvula, Y. Sterling, W. Martin, K. Stephens, L. White

“…We evaluated allergen concentrations, skin test sensitivities, and asthma morbidity for 182 children, aged 4–12 years, with moderate to severe asthma, enrolled 18 months after Katrina, from the city of New Orleans and the surrounding parishes that were impacted by the storm, into the Head-off Environmental Asthma in Louisiana (HEAL) observational study. …”
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Incidental Phaeochromocytoma on Staging PET-CT in a Patient with a Sigmoid Tumour and Situs Inversalis Totalis by M. R. Boland, A. J. Lowery, S. Walsh, D. Beddy, R. S. Prichard, D. O’Shea, S. J. Skehan, E. W. McDermott

“…This case highlights the importance of accurately identifying functioning adrenal tumours before elective surgery as undiagnosed phaeochromocytomas carry significant intraoperative morbidity/mortality. Right adrenalectomy was made easier in this patient by the liver’s unique position. …”
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Atypical Presentation of Disseminated Zoster in a Patient with Rheumatoid Arthritis by Nirav Patel, Davinder Singh, Krunal Patel, Shadab Ahmed, Prachi Anand

“…High index of suspicion is needed to make the diagnosis promptly and to initiate therapy to decrease mortality and morbidity.…”
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The burden of hepatitis E virus infection among Ghanaian pregnant women by Husein Bagulo, Husein Bagulo, Ayodele O. Majekodunmi, Ayodele O. Majekodunmi, Susan C. Welburn, Susan C. Welburn, Langbong Bimi

“…Also, the drinking water source and the toilet type accurately predicted HEV IgG seroprevalence in both univariate and multivariate models.DiscussionPregnancy care must be significantly improved to reduce maternal and foetal morbidity and mortality.…”
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AMPK: An energy sensor for non-small cell lung cancer progression and treatment by Zhi-Ting Zhong, Xu-Yan Wang, Ying Pan, Ke Zhou, Jing-Hui Chen, Yu-Qi Gao, Bo Dai, Zhi-Ling Zhou, Rui-Qi Wang

“…Lung cancer (LC) is the leading cause of cancer-related morbidity and mortality in China, with non-small cell lung cancer (NSCLC) accounting for 85 % of the overall lung cancer cases. …”
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Chronic Microvascular Complications in Sulfonylureas-Treated Diabetic Patients: Correlations with Glycemic Control, Risk Factors and Duration of the Disease by Luminita-Georgeta Confederat, Roxana Stefan, Mihaela-Iustina Condurache, Oana-Maria Dragostin

“…<b>Background</b>: Diabetes has become one of the most challenging public health problems due to the alarming increase in prevalence and the morbidity and mortality attributed to its acute and chronic complications. …”
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Regulatory Role of GSK-3β on NF-κB, Nitric Oxide, and TNF-α in Group A Streptococcal Infection by Yu-Tzu Chang, Chia-Ling Chen, Chiou-Feng Lin, Shiou-Ling Lu, Miao-Huei Cheng, Chih-Feng Kuo, Yee-Shin Lin

“…Efforts to minimize the associated morbidity and mortality represent a critical issue. …”
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Identifying common pathways for doxorubicin and carfilzomib-induced cardiotoxicities: transcriptomic and epigenetic profiling by Conagh Kelly, Dylan J. Kiltschewskij, Angeline J.W. Leong, Tatt Jhong Haw, Amanda J. Croft, Lohis Balachandran, Dongqing Chen, Danielle R. Bond, Heather J. Lee, Murray J. Cairns, Aaron L. Sverdlov, Doan T. M. Ngo

“…Abstract Cancer therapy-related cardiovascular toxicity (CTR-CVT) is now recognised as one of the leading causes of long-term morbidity and mortality in cancer patients. To date, potential overlapping cardiotoxicity mechanism(s) across different chemotherapeutic classes have not been elucidated. …”
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Public health implications of the relationship between socioeconomic and cultural dimensions on immunization coverage in Bangkalan, East Java by Ulfah Nurnaningsih Herya, Rachmawat Windi Chusniah, Rahmawati Indana Tri, Katmawanti Septa, Samah Dea Aflah, Wahyuni Oktavia Sri, Aulia Syafa Nairah, Az Zahra Aulia Rizqia

“…Misconceptions regarding vaccinations are the cause of this poor coverage, which raises the risk of morbidity and death. According to WHO, 1.5 million children die each year from illnesses that may be prevented because they were not vaccinated, underscoring the wider impact on public health. …”
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Perceived husbands’ support during pregnancy and childbirth among women in yenagoa metropolis, bayelsa state by Jessica Agada Jimmy, Arunibebi Lamawal Lawrence, Maureen B Nkamare, Wonyinbarakemi Ladi Berefagha

“…Insufficient support from husbands can contribute to increased maternal morbidity and mortality. Objectives: This study evaluates the levels of perceived emotional, physical, and informational support provided by husbands to their wives during pregnancy and childbirth. …”
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