Breast reconstruction with deep inferior epigastric artery perforator flap (DIEP-flap). History of development by I. S. Duadze, A. D. Zikiryakhodzhaev, A. S. Sukhotko, M. V. Starkova, F. N. Usov, D. V. Bagdasarova, D. Sh. Dzhabrailova, Sh. G. Khakimova

“…Based on the literature review, it was found that breast reconstruction with the help of perforating flaps is still an area of innovation and constant progress: research in this area to date is mainly aimed at reducing the morbidity of the donor area and methods for isolating recipient vessels, shortening the rehabilitation period and developing reproducible reconstruction method.…”
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Hereditary Hyperferritinemia-Cataract Syndrome in 3 Generations of a Family in East Tennessee by Heidi A. Worth, Zachary Marlette, David Aljadir, Ronald Lands

“…The result is often an expensive, invasive evaluation for iron overload, followed by a well-intended prescription for a series of phlebotomies that delivers morbidity instead of benefit. We present a father with an elevated ferritin and heterozygosity for H63D HFE mutation whose clinical course followed this path. …”
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Bone-Targeted Therapies in Metastatic Castration-Resistant Prostate Cancer: Evolving Paradigms by Joelle El-Amm, Ashley Freeman, Nihar Patel, Jeanny B. Aragon-Ching

“…Majority of patients with metastatic castrate resistant prostate cancer (mCRPC) develop bone metastases which results in significant morbidity and mortality as a result of skeletal-related events (SREs). …”
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Coxiella Endocarditis as the Cause of Recurrent Fever and Brain Abscess in a Patient with Complex Congenital Heart Disease: A Case Report and Literature Review by Ioannis A. Ziogas, Alexandros P. Evangeliou, Olga Tsachouridou, Alexandra Arvanitaki, Afroditi Tsona, Vassilios Kamperidis, Marianthi Papagianni, Theofilos Panagiotidis, Ilias A. Tourtounis, George Giannakoulas, Symeon Metallidis

“…Blood culture-negative infective endocarditis (BCNIE) can present subtly and is associated with a diagnostic delay leading to increased morbidity and mortality. Case Report. We present the case of an 18-year-old male with a history of complex congenital heart disease and 3-year intermittent episodes of fever of unknown origin, who was referred to our hospital for upper and lower extremity focal seizures. …”
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A Preliminary Study: The Effect of Slow Deep Breathing Exercise (SDBE) on Resting Heart Rate and Respiration Rate of Hypertension Patients by Candrawati Susiana, Oktaviana Husnul Afifah Rizky, Bening Ati Viva Ratih, Mustofa Mustofa

“…Examination of vital signs such as resting pulse and respiratory rate are parameters of hypertension morbidity. One alternative therapy for hypertension is slow, deep breathing exercises. …”
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Epidemiology, Prognosis, and Evolution of Management of Septic Shock in a French Intensive Care Unit: A Five Years Survey by Nicolas Boussekey, Juliette Cantrel, Lise Dorchin Debrabant, Joachim Langlois, Patick Devos, Agnes Meybeck, Arnaud Chiche, Hugues Georges, Olivier Leroy

“…These six mortality risk factors recovered allow screening immediately septic shock patients with a high mortality risk. Morbidity improved with time (diminution of septic shock complications, increase of the number of days alive free from mechanical ventilation and vasopressors on day 28), concomitant to an evolution of the management (earlier institution of all replacement and medical therapies and more initial volume expansion). …”
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The Clinical and Radiological Outcome of Bovine Hydroxyapatite (Bio Hydrox) as Bone Graft by Arifin, Ferdiansyah Mahyudin, Mouli Edward

“…While autografting has long been considered the gold standard, it has limitations, including a restricted supply and donor site morbidity. These limitations, along with those associated with allografts, have led to the development of bovine hydroxyapatite (BHA) as a bone graft substitute. …”
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Systematic Review of the Relationship between Acute and Late Gastrointestinal Toxicity after Radiotherapy for Prostate Cancer by Matthew Sean Peach, Timothy N. Showalter, Nitin Ohri

“…In this systematic review of published reports, we found that late gastrointestinal toxicity following prostate radiotherapy seems to be statistically and potentially causally related to acute gastrointestinal morbidity as a consequential effect. We submit that acute gastrointestinal toxicity may be used to identify at-risk patients who may benefit from additional attention for medical interventions and close follow-up to prevent late toxicity. …”
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From Bilateral Periorbital Necrotic Wound to Fungal Brain Abscess: A Complicated Case of COVID-19-Associated Mucormycosis by Bahram Eshraghi, Nastaran-Sadat Hosseini, Rasoul Mohammadi, Seyed Hamid Reza Abtahi, Alireza Ramezani-Majd, Roya Azad, Mohsen Pourazizi

“…An alarming surge in morbidity and mortality attributed to mucormycosis concurrent with coronavirus disease 2019 (COVID-19) has emerged as a cause for concern during the current outbreak of COVID-19. …”
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The Role of Inflammation in the Pathogenesis of Preeclampsia by Michał Michalczyk, Aleksander Celewicz, Marta Celewicz, Paula Woźniakowska-Gondek, Rafał Rzepka

“…Preeclampsia (PE) affects 5-8% of pregnant women, and it is the major cause of perinatal morbidity and mortality. It is defined as arterial hypertension in women after 20 weeks of gestation which cooccurs with proteinuria (300 mg/d) or as arterial hypertension which is accompanied by one of the following: renal failure, liver dysfunction, hematological or neurological abnormalities, intrauterine growth restriction, or uteroplacental insufficiency. …”
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Magnetic Apposition across the Epiglottis: Radiographic and Operative Correlation of a Rare Hypopharyngeal Foreign Body by Yeli Pi, Shilpa Radhakrishnan, Yaser Alrajhi, Ravi Bhargava

“…Rare-earth magnet ingestions are a subset of foreign body ingestions and can result in significant morbidity secondary to pressure necrosis. These magnets are best visualized radiographically, typically located in the gastrointestinal tract. …”
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Current Management of Pancreatic Neuroendocrine Tumors: From Demolitive Surgery to Observation by Ilenia Bartolini, Lapo Bencini, Matteo Risaliti, Maria Novella Ringressi, Luca Moraldi, Antonio Taddei

“…The risks of under/overtreatment should be carefully evaluated with the patient and balanced with the potential morbidities related to surgery. The importance of the Ki-67 index as a prognostic factor is still debated as well. …”
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Analysis of the Pro- and Anti-Inflammatory Cytokines Secreted by Adult Stem Cells during Differentiation by Amy L. Strong, Jeffrey M. Gimble, Bruce A. Bunnell

“…The abundance of ASCs in adipose tissue and easy accessibility with relatively little donor site morbidity make them attractive candidate cells for tissue engineering and regenerative medicine. …”
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Gallbladder Volvulus in a Patient with Type I Choledochal Cyst: A Case Report and Review of the Literature by George Younan, Max Schumm, Fadwa Ali, Kathleen K. Christians

“…Prompt diagnosis and surgical management of gallbladder volvulus is important to avoid the morbidity and mortality of gangrenous cholecystitis and biliary peritonitis in a frail old population of patients. …”
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The Second Canadian Symposium on Hepatitis C Virus: A Call to Action by Jason Grebely, Marc Bilodeau, Jordan J Feld, Julie Bruneau, Benedikt Fischer, Jennifer F Raven, Eve Roberts, Norma Choucha, Rob P Myers, Selena M Sagan, Joyce A Wilson, Frank Bialystok, D Lorne Tyrrell, Michael Houghton, Mel Krajden, on behalf of the National CIHR Research Training Program in Hepatitis C

“…In Canada, hepatitis C virus (HCV) infection results in considerable morbidity, mortality and health-related costs. Within the next three to 10 years, it is expected that tolerable, short-duration (12 to 24 weeks) therapies capable of curing >90% of those who undergo treatment will be approved. …”
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Prooxidant-Antioxidant Balance in Umbilical Cord Blood of Infants with Meconium Stained of Amniotic Fluid by Mohammad Hassan Arjmand, Farhat Ahmad Shah, Masoud Saleh Moghadam, Fatemeh Tara, Amin Jalili, Mojtaba Mosavi Bazaz, Daryoush Hamidi Alamdari

“…Passage of meconium in amniotic fluid is associated with increase of neonatal mortality and morbidity. This complication occurs in about 15% of infants and is more widespread in postterm neonates. …”
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Neuroinflammation as Fuel for Axonal Regeneration in the Injured Vertebrate Central Nervous System by Ilse Bollaerts, Jessie Van houcke, Lien Andries, Lies De Groef, Lieve Moons

“…Damage to the central nervous system (CNS) is one of the leading causes of morbidity and mortality in elderly, as repair after lesions or neurodegenerative disease usually fails because of the limited capacity of CNS regeneration. …”
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Gut-Heart Axis: Microbiome Involvement in Restrictive Cardiomyopathies by Samuel Jaimez-Alvarado, Itzel Ivonn López-Tenorio, Javier Barragán-De los Santos, Dannya Coral Bello-Vega, Francisco Javier Roldán Gómez, Amedeo Amedei, Enrique Alexander Berrios-Bárcenas, María Magdalena Aguirre-García

“…These cardiomyopathies are often difficult to diagnose and so result in significant morbidity and mortality. The human microbiome, composed of billions of microorganisms, influences various physiological and pathological processes, including cardiovascular health. …”
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Clinical Characteristics and Outcomes of Surgical Patients with Intensive Care Unit Lengths of Stay of 90 Days and Greater by Verena Martini, Ann-Kathrin Lederer, Claudia Laessle, Frank Makowiec, Stefan Utzolino, Stefan Fichtner-Feigl, Lampros Kousoulas

“…The aim of this study was to evaluate the influence of prolonged length of stay in an intensive care unit (ICU) on the mortality and morbidity of surgical patients. Methods. We performed a monocentric and retrospective observational study in the surgical critical care unit of the department of surgery at the Medical Center of the University of Freiburg, Germany. …”
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Case report: Advanced age at transplantation and pre-emptive treatment with dupilumab in DOCK8 deficiency by Sophia Trombello, Sophia Trombello, Andrea Jarisch, Andre Willasch, Eva Rettinger, Julia Fekadu-Siebald, Dirk Holzinger, Dirk Holzinger, Roland Adelmann, Peter Bader, Shahrzad Bakhtiar

“…Additionally, in a review of the literature, we summarize morbidity and outcome in DOCK8-deficient patients older than 8 years of age receiving alloHSCT. …”
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